Mechanism for the protective effect of diallyl disulfide against cyclophosphamide acute urotoxicity in rats

Food and Chemical Toxicology

Volumn 64, Issue , 2014, Pages 110-118

  Kim, Sung Hwan ^a   Lee, In Chul ^a   Baek, Hyung Seon ^a   Shin, In Sik ^a,b   Moon, Changjong ^a   Bae, Chun Sik ^a   Kim, Sung Ho ^a   Kim, Jong Choon ^a   Kim, Hyoung Chin ^b  

^a Chonnam National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Cyclophosphamide; Cytochrome P450; Diallyl disulfide; Nrf 2; Oxidative stress; Urotoxicity

Indexed keywords

ACROLEIN; CATALASE; CYCLOPHOSPHAMIDE; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2C11; CYTOCHROME P450 3A1; DIALLYL DISULFIDE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; MALONALDEHYDE; QUINONE OXIDOREDUCTASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BLADDER INJURY; BLADDER TOXICITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HEMORRHAGIC CYSTITIS; MALE; METABOLIC ACTIVATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; TOXICITY;

RATTUS;

CYCLOPHOSPHAMIDE; CYTOCHROME P450; DIALLYL DISULFIDE; NRF-2; OXIDATIVE STRESS; UROTOXICITY;

ALLYL COMPOUNDS; ANIMALS; APOPTOSIS; CATALASE; CYCLOPHOSPHAMIDE; DISULFIDES; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MALE; MALONDIALDEHYDE; ORGAN SIZE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; URINARY BLADDER;

EID: 84890419214     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.11.023     Document Type: Article

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