-
1
-
-
33745761352
-
Open probability of the epithelial sodium channel is regulated by intracellular sodium
-
Anantharam A, Tian Y, Palmer LG. Open probability of the epithelial sodium channel is regulated by intracellular sodium. J Physiol 574: 333-347, 2006.
-
(2006)
J Physiol
, vol.574
, pp. 333-347
-
-
Anantharam, A.1
Tian, Y.2
Palmer, L.G.3
-
2
-
-
0033695107
-
Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels
-
Askwith CC, Cheng C, Ikuma M, Benson C, Price MP, Welsh MJ. Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels. Neuron 26: 133-141, 2000.
-
(2000)
Neuron
, vol.26
, pp. 133-141
-
-
Askwith, C.C.1
Cheng, C.2
Ikuma, M.3
Benson, C.4
Price, M.P.5
Welsh, M.J.6
-
3
-
-
79960866459
-
PLUNC: A multifunctional surfactant of the airways
-
Bartlett JA, Gakhar L, Penterman J, Singh PK, Mallampalli RK, Porter E, McCray PB Jr. PLUNC: a multifunctional surfactant of the airways. Biochem Soc Trans 39: 1012-1016.
-
Biochem Soc Trans
, vol.39
, pp. 1012-1016
-
-
Bartlett, J.A.1
Gakhar, L.2
Penterman, J.3
Singh, P.K.4
Mallampalli, R.K.5
Porter, E.6
McCray Jr., P.B.7
-
4
-
-
0031967690
-
The BPI/LBP family of proteins: A structural analysis of conserved regions
-
Beamer LJ, Carroll SF, Eisenberg D. The BPI/LBP family of proteins: a structural analysis of conserved regions. Protein Sci 7: 906-914, 1998.
-
(1998)
Protein Sci
, vol.7
, pp. 906-914
-
-
Beamer, L.J.1
Carroll, S.F.2
Eisenberg, D.3
-
5
-
-
38749090635
-
Differential epithelial expression of the putative innate immune molecule SPLUNC1 in cystic fibrosis
-
Bingle L, Barnes FA, Cross SS, Rassl D, Wallace WA, Campos MA, Bingle CD. Differential epithelial expression of the putative innate immune molecule SPLUNC1 in cystic fibrosis. Respir Res 8: 79, 2007.
-
(2007)
Respir Res
, vol.8
, pp. 79
-
-
Bingle, L.1
Barnes, F.A.2
Cross, S.S.3
Rassl, D.4
Wallace, W.A.5
Campos, M.A.6
Bingle, C.D.7
-
6
-
-
78751647166
-
Effect of a temperature increase in the non-noxious range on proton-evoked ASIC and TRPV1 activity
-
Blanchard MG, Kellenberger S. Effect of a temperature increase in the non-noxious range on proton-evoked ASIC and TRPV1 activity. Pflügers Arch 461: 123-139, 2011.
-
(2011)
Pflügers Arch
, vol.461
, pp. 123-139
-
-
Blanchard, M.G.1
Kellenberger, S.2
-
7
-
-
16844362295
-
Flexible peptides and cytoplasmic gels
-
Bray D. Flexible peptides and cytoplasmic gels. Genome Biol 6: 106, 2005.
-
(2005)
Genome Biol
, vol.6
, pp. 106
-
-
Bray, D.1
-
8
-
-
0036012499
-
Transepithelial measurements of bicarbonate secretion in Calu-3 cells
-
Bridges RJ. Transepithelial measurements of bicarbonate secretion in Calu-3 cells. Methods Mol Med 70: 111-128, 2002.
-
(2002)
Methods Mol Med
, vol.70
, pp. 111-128
-
-
Bridges, R.J.1
-
9
-
-
34250207969
-
+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit
-
+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit. J Biol Chem 282: 6153-6160, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 6153-6160
-
-
Bruns, J.B.1
Carattino, M.D.2
Sheng, S.3
Maarouf, A.B.4
Weisz, O.A.5
Pilewski, J.M.6
Hughey, R.P.7
Kleyman, T.R.8
-
10
-
-
77954287478
-
Protein annotation and modelling servers at University College London
-
Buchan DW, Ward SM, Lobley AE, Nugent TC, Bryson K, Jones DT. Protein annotation and modelling servers at University College London. Nucleic Acids Res 38: W563-568.
-
Nucleic Acids Res
, vol.38
-
-
Buchan, D.W.1
Ward, S.M.2
Lobley, A.E.3
Nugent, T.C.4
Bryson, K.5
Jones, D.T.6
-
12
-
-
0027958441
-
+ channel is made of three homologous subunits
-
+ channel is made of three homologous subunits. Nature 367: 463-467, 1994.
-
(1994)
Nature
, vol.367
, pp. 463-467
-
-
Canessa, C.M.1
Schild, L.2
Buell, G.3
Thorens, B.4
Gautschi, I.5
Horisberger, J.D.6
Rossier, B.C.7
-
13
-
-
38349081051
-
Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel
-
Carattino MD, Passero CJ, Steren CA, Maarouf AB, Pilewski JM, Myerburg MM, Hughey RP, Kleyman TR. Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel. Am J Physiol Renal Physiol 294: F47-F52, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Carattino, M.D.1
Passero, C.J.2
Steren, C.A.3
Maarouf, A.B.4
Pilewski, J.M.5
Myerburg, M.M.6
Hughey, R.P.7
Kleyman, T.R.8
-
15
-
-
35748980587
-
Function and regulation of SPLUNC1 protein in Mycoplasma infection and allergic inflammation
-
Chu HW, Thaikoottathil J, Rino JG, Zhang G, Wu Q, Moss T, Refaeli Y, Bowler R, Wenzel SE, Chen Z, Zdunek J, Breed R, Young R, Allaire E, Martin RJ. Function and regulation of SPLUNC1 protein in Mycoplasma infection and allergic inflammation. J Immunol 179: 3995-4002, 2007.
-
(2007)
J Immunol
, vol.179
, pp. 3995-4002
-
-
Chu, H.W.1
Thaikoottathil, J.2
Rino, J.G.3
Zhang, G.4
Wu, Q.5
Moss, T.6
Refaeli, Y.7
Bowler, R.8
Wenzel, S.E.9
Chen, Z.10
Zdunek, J.11
Breed, R.12
Young, R.13
Allaire, E.14
Martin, R.J.15
-
16
-
-
0346103648
-
Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium
-
Coakley RD, Grubb BR, Paradiso AM, Gatzy JT, Johnson LG, Kreda SM, O'Neal WK, Boucher RC. Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium. Proc Natl Acad Sci USA 100: 16083-16088, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 16083-16088
-
-
Coakley, R.D.1
Grubb, B.R.2
Paradiso, A.M.3
Gatzy, J.T.4
Johnson, L.G.5
Kreda, S.M.6
O'Neal, W.K.7
Boucher, R.C.8
-
17
-
-
2342629343
-
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
-
Diochot S, Baron A, Rash LD, Deval E, Escoubas P, Scarzello S, Salinas M, Lazdunski M. A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons. EMBO J 23: 1516-1525, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 1516-1525
-
-
Diochot, S.1
Baron, A.2
Rash, L.D.3
Deval, E.4
Escoubas, P.5
Scarzello, S.6
Salinas, M.7
Lazdunski, M.8
-
18
-
-
0037040995
-
Regulation of the epithelial sodium channel by serine proteases in human airways
-
Donaldson SH, Hirsh A, Li DC, Holloway G, Chao J, Boucher RC, Gabriel SE. Regulation of the epithelial sodium channel by serine proteases in human airways. J Biol Chem 277: 8338-8345, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 8338-8345
-
-
Donaldson, S.H.1
Hirsh, A.2
Li, D.C.3
Holloway, G.4
Chao, J.5
Boucher, R.C.6
Gabriel, S.E.7
-
19
-
-
79959194221
-
SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice
-
Gally F, Di YP, Smith SK, Minor MN, Liu Y, Bratton DL, Frasch SC, Michels NM, Case SR, Chu HW. SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice. Am J Pathol 178: 2159-2167.
-
Am J Pathol
, vol.178
, pp. 2159-2167
-
-
Gally, F.1
Di, Y.P.2
Smith, S.K.3
Minor, M.N.4
Liu, Y.5
Bratton, D.L.6
Frasch, S.C.7
Michels, N.M.8
Case, S.R.9
Chu, H.W.10
-
20
-
-
67650488822
-
SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage
-
Garcia-Caballero A, Rasmussen JE, Gaillard E, Watson MJ, Olsen JC, Donaldson SH, Stutts MJ, Tarran R. SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage. Proc Natl Acad Sci USA 106: 11412-11417, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11412-11417
-
-
Garcia-Caballero, A.1
Rasmussen, J.E.2
Gaillard, E.3
Watson, M.J.4
Olsen, J.C.5
Donaldson, S.H.6
Stutts, M.J.7
Tarran, R.8
-
21
-
-
84885084821
-
Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways
-
Garland AL, Walton WG, Coakley RD, Tan CD, Gilmore RC, Hobbs CA, Tripathy A, Clunes LA, Bencharit S, Stutts MJ, Betts L, Redinbo MR, Tarran R. Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways. Proc Natl Acad Sci USA 110: 15973-15978, 2013.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 15973-15978
-
-
Garland, A.L.1
Walton, W.G.2
Coakley, R.D.3
Tan, C.D.4
Gilmore, R.C.5
Hobbs, C.A.6
Tripathy, A.7
Clunes, L.A.8
Bencharit, S.9
Stutts, M.J.10
Betts, L.11
Redinbo, M.R.12
Tarran, R.13
-
22
-
-
0030945484
-
Epithelial sodium channels: Function, structure, and regulation
-
Garty H, Palmer LG. Epithelial sodium channels: function, structure, and regulation. Physiol Rev 77: 359-396, 1997.
-
(1997)
Physiol Rev
, vol.77
, pp. 359-396
-
-
Garty, H.1
Palmer, L.G.2
-
23
-
-
38149032285
-
Hydroxyurea attenuates activated neutrophil-mediated sickle erythrocyte membrane phosphatidylserine exposure and adhesion to pulmonary vascular endothelium
-
Haynes J Jr, Obiako B, Hester RB, Baliga BS, Stevens T. Hydroxyurea attenuates activated neutrophil-mediated sickle erythrocyte membrane phosphatidylserine exposure and adhesion to pulmonary vascular endothelium. Am J Physiol Heart Circ Physiol 294: H379-H385, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Haynes Jr., J.1
Obiako, B.2
Hester, R.B.3
Baliga, B.S.4
Stevens, T.5
-
24
-
-
84884284486
-
Does epithelial sodium channel hyperactivity contribute to CF lung disease?
-
Hobbs CA, Da Tan C, Tarran R. Does epithelial sodium channel hyperactivity contribute to CF lung disease? J Physiol 591: 4377-4387, 2013.
-
(2013)
J Physiol
, vol.591
, pp. 4377-4387
-
-
Hobbs, C.A.1
da Tan, C.2
Tarran, R.3
-
25
-
-
0141621280
-
+ channel involves proteolytic processing of the alpha- and gamma-subunits
-
+ channel involves proteolytic processing of the alpha- and gamma-subunits. J Biol Chem 278: 37073-37082, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 37073-37082
-
-
Hughey, R.P.1
Mueller, G.M.2
Bruns, J.B.3
Kinlough, C.L.4
Poland, P.A.5
Harkleroad, K.L.6
Carattino, M.D.7
Kleyman, T.R.8
-
26
-
-
0033578684
-
Protein secondary structure prediction based on position-specific scoring matrices
-
Jones DT. Protein secondary structure prediction based on position-specific scoring matrices. J Mol Biol 292: 195-202, 1999.
-
(1999)
J Mol Biol
, vol.292
, pp. 195-202
-
-
Jones, D.T.1
-
27
-
-
78650934293
-
+ channel alpha subunit reveals a mechanism of channel activation by proteases
-
+ channel alpha subunit reveals a mechanism of channel activation by proteases. J Biol Chem 286: 649-660.
-
J Biol Chem
, vol.286
, pp. 649-660
-
-
Kashlan, O.B.1
Adelman, J.L.2
Okumura, S.3
Blobner, B.M.4
Zuzek, Z.5
Hughey, R.P.6
Kleyman, T.R.7
Grabe, M.8
-
29
-
-
0033950079
-
The importance of being proline: The interaction of proline-rich motifs in signaling proteins with their cognate domains
-
Kay BK, Williamson MP, Sudol M. The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J 14: 231-241, 2000.
-
(2000)
FASEB J
, vol.14
, pp. 231-241
-
-
Kay, B.K.1
Williamson, M.P.2
Sudol, M.3
-
30
-
-
58149529356
-
Tracheobronchial air-liquid interface cell culture: A model for innate mucosal defense of the upper airways?
-
Kesimer M, Kirkham S, Pickles RJ, Henderson AG, Alexis NE, Demaria G, Knight D, Thornton DJ, Sheehan JK. Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol 296: L92-L100, 2009.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.296
-
-
Kesimer, M.1
Kirkham, S.2
Pickles, R.J.3
Henderson, A.G.4
Alexis, N.E.5
Demaria, G.6
Knight, D.7
Thornton, D.J.8
Sheehan, J.K.9
-
31
-
-
84856324259
-
Mass spectrometric analysis of mucin core proteins
-
Kesimer M, Sheehan JK. Mass spectrometric analysis of mucin core proteins. Methods Mol Biol 842: 67-79.
-
Methods Mol Biol
, vol.842
, pp. 67-79
-
-
Kesimer, M.1
Sheehan, J.K.2
-
32
-
-
0036194724
-
Mucus clearance as a primary innate defense mechanism for mammalian airways
-
Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest 109: 571-577, 2002.
-
(2002)
J Clin Invest
, vol.109
, pp. 571-577
-
-
Knowles, M.R.1
Boucher, R.C.2
-
33
-
-
78049266320
-
The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway
-
McGillivary G, Bakaletz LO. The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway. PLoS One 5: e13224.
-
PLoS One
, vol.5
-
-
McGillivary, G.1
Bakaletz, L.O.2
-
34
-
-
4644243948
-
Selective regulation of acid-sensing ion channel 1 by serine proteases
-
Poirot O, Vukicevic M, Boesch A, Kellenberger S. Selective regulation of acid-sensing ion channel 1 by serine proteases. J Biol Chem 279: 38448-38457, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 38448-38457
-
-
Poirot, O.1
Vukicevic, M.2
Boesch, A.3
Kellenberger, S.4
-
36
-
-
30944452609
-
Restoring airway surface liquid in cystic fibrosis
-
Ratjen F. Restoring airway surface liquid in cystic fibrosis. N Engl J Med 354: 291-293, 2006.
-
(2006)
N Engl J Med
, vol.354
, pp. 291-293
-
-
Ratjen, F.1
-
38
-
-
77952891046
-
SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes
-
Rollins BM, Garcia-Caballero A, Stutts MJ, Tarran R. SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes. Channels (Austin) 4: 255-259.
-
Channels (Austin)
, vol.4
, pp. 255-259
-
-
Rollins, B.M.1
Garcia-Caballero, A.2
Stutts, M.J.3
Tarran, R.4
-
39
-
-
64149083549
-
Activation of the epithelial sodium channel (ENaC) by serine proteases
-
Rossier BC, Stutts MJ. Activation of the epithelial sodium channel (ENaC) by serine proteases. Annu Rev Physiol 71: 361-379, 2009.
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 361-379
-
-
Rossier, B.C.1
Stutts, M.J.2
-
41
-
-
33645698431
-
Proteomic analysis of nasal cells from cystic fibrosis patients and non-cystic fibrosis control individuals: Search for novel biomarkers of cystic fibrosis lung disease
-
Roxo-Rosa M, da Costa G, Luider TM, Scholte BJ, Coelho AV, Amaral MD, Penque D. Proteomic analysis of nasal cells from cystic fibrosis patients and non-cystic fibrosis control individuals: search for novel biomarkers of cystic fibrosis lung disease. Proteomics 6: 2314-2325, 2006.
-
(2006)
Proteomics
, vol.6
, pp. 2314-2325
-
-
Roxo-Rosa, M.1
da Costa, G.2
Luider, T.M.3
Scholte, B.J.4
Coelho, A.V.5
Amaral, M.D.6
Penque, D.7
-
42
-
-
70449623627
-
Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death
-
Sherwood TW, Askwith CC. Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death. J Neurosci 29: 14371-14380, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 14371-14380
-
-
Sherwood, T.W.1
Askwith, C.C.2
-
43
-
-
0033986427
-
Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface
-
Snyder PM. Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface. J Clin Invest 105: 45-53, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 45-53
-
-
Snyder, P.M.1
-
44
-
-
0028982894
-
CFTR as a cAMP-dependent regulator of sodium channels
-
Stutts MJ, Canessa CM, Olsen JC, Hamrick M, Cohn JA, Rossier BC, Boucher RC. CFTR as a cAMP-dependent regulator of sodium channels. Science 269: 847-850, 1995.
-
(1995)
Science
, vol.269
, pp. 847-850
-
-
Stutts, M.J.1
Canessa, C.M.2
Olsen, J.C.3
Hamrick, M.4
Cohn, J.A.5
Rossier, B.C.6
Boucher, R.C.7
-
45
-
-
0034885663
-
The CF salt controversy: In vivo observations and therapeutic approaches
-
Tarran R, Grubb BR, Parsons D, Picher M, Hirsh AJ, Davis CW, Boucher RC. The CF salt controversy: in vivo observations and therapeutic approaches. Mol Cell 8: 149-158, 2001.
-
(2001)
Mol Cell
, vol.8
, pp. 149-158
-
-
Tarran, R.1
Grubb, B.R.2
Parsons, D.3
Picher, M.4
Hirsh, A.J.5
Davis, C.W.6
Boucher, R.C.7
-
46
-
-
33646138489
-
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia
-
Tarran R, Trout L, Donaldson SH, Boucher RC. Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia. J Gen Physiol 127: 591-604, 2006.
-
(2006)
J Gen Physiol
, vol.127
, pp. 591-604
-
-
Tarran, R.1
Trout, L.2
Donaldson, S.H.3
Boucher, R.C.4
-
48
-
-
0036238921
-
N-linked gly-cosylation is critical for the plasma membrane localization of nephrin
-
Yan K, Khoshnoodi J, Ruotsalainen V, Tryggvason K. N-linked gly-cosylation is critical for the plasma membrane localization of nephrin. J Am Soc Nephrol 13: 1385-1389, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1385-1389
-
-
Yan, K.1
Khoshnoodi, J.2
Ruotsalainen, V.3
Tryggvason, K.4
-
49
-
-
38649121475
-
Effect of SPLUNC1 protein on the Pseudomonas aeruginosa and Epstein-Barr virus
-
Zhou HD, Li XL, Li GY, Zhou M, Liu HY, Yang YX, Deng T, Ma J, Sheng SR. Effect of SPLUNC1 protein on the Pseudomonas aeruginosa and Epstein-Barr virus. Mol Cell Biochem 309: 191-197, 2008.
-
(2008)
Mol Cell Biochem
, vol.309
, pp. 191-197
-
-
Zhou, H.D.1
Li, X.L.2
Li, G.Y.3
Zhou, M.4
Liu, H.Y.5
Yang, Y.X.6
Deng, T.7
Ma, J.8
Sheng, S.R.9
|