Lysine-based surfactants in nanovesicle formulations: the role of cationic charge position and hydrophobicity in in vitro cytotoxicity and intracellular delivery

Nanotoxicology

Volumn 8, Issue 4, 2014, Pages 404-421

  Nogueira, Daniele Rubert ^a   Carmen Morán, Maria Del ^a,c   Mitjans, Montserrat ^a,c   Pérez, Lourdes ^b   Ramos, David ^a   De Lapuente, Joaquín ^a   Pilar Vinardell, Maria ^a,c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^c CSIC   (Spain)

Author keywords

Cell culture; Cell internalisation; Drug delivery; Nanotoxicity; PH sensitivity

Indexed keywords

AMPHOPHILE; CHOLESTEROL; DIMYRISTOYLPHOSPHATIDYLCHOLINE; LACTATE DEHYDROGENASE; LYSINE; NANOPARTICLE; NANOVESICLE; SURFACTANT; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BLOOD COMPATIBILITY; CELL CYCLE; CELL LINE; CELL PH; CELL VIABILITY; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DNA DAMAGE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENDOCYTOSIS; GENOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; INTERNALIZATION; MITOCHONDRIAL TOXICITY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SURFACE CHARGE;

3T3 CELLS; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CATIONS; CELL CYCLE; CELL SURVIVAL; DNA DAMAGE; DRUG CARRIERS; ERYTHROCYTES; HELA CELLS; HEMOLYSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTRACELLULAR SPACE; LYSINE; MICE; NANOSTRUCTURES; RATS; SURFACE-ACTIVE AGENTS;

EID: 84890361800     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2013.793779     Document Type: Article

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