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Volumn 23, Issue 1, 2014, Pages 145-156

Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; GLUCOSE 6 PHOSPHATE; HEXOKINASE; HEXOKINASE 1; HEXOKINASE 2; MESSENGER RNA; PARKIN; PHOSPHOTRANSFERASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; TETRAMETHYLRHODAMINE ETHYL ESTER; UNCLASSIFIED DRUG;

EID: 84890339047     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt407     Document Type: Article
Times cited : (77)

References (47)
  • 1
    • 84856463380 scopus 로고    scopus 로고
    • Autosomal recessive parkinsonism
    • Bonifati, V. (2012) Autosomal recessive parkinsonism. Parkinsonism Relat. Disord., 18(Suppl. 1), S4-S6.
    • (2012) Parkinsonism Relat. Disord. , vol.18 , Issue.SUPPL. 1
    • Bonifati, V.1
  • 2
    • 33745589773 scopus 로고    scopus 로고
    • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
    • Clark, I.E., Dodson, M.W., Jiang, C., Cao, J.H., Huh, J.R., Seol, J.H., Yoo, S.J., Hay, B.A. and Guo, M. (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature, 441, 1162-1166.
    • (2006) Nature , vol.441 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Cao, J.H.4    Huh, J.R.5    Seol, J.H.6    Yoo, S.J.7    Hay, B.A.8    Guo, M.9
  • 3
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra, D., Tanaka, A., Suen, D.F. and Youle, R.J. (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol., 183, 795-803.
    • (2008) J. Cell Biol. , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 4
    • 33745602748 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
    • Park, J., Lee, S.B., Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J.M. et al. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature, 441, 1157-1161.
    • (2006) Nature , vol.441 , pp. 1157-1161
    • Park, J.1    Lee, S.B.2    Lee, S.3    Kim, Y.4    Song, S.5    Kim, S.6    Bae, E.7    Kim, J.8    Shong, M.9    Kim, J.M.10
  • 5
    • 45249112594 scopus 로고    scopus 로고
    • Characterization of PINK1 processing, stability, and subcellular localization
    • Lin, W. and Kang, U.J. (2008) Characterization of PINK1 processing, stability, and subcellular localization. J. Neurochem., 106, 464-474.
    • (2008) J. Neurochem. , vol.106 , pp. 464-474
    • Lin, W.1    Kang, U.J.2
  • 6
    • 37549029702 scopus 로고    scopus 로고
    • Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1
    • Takatori, S., Ito, G. and Iwatsubo, T. (2008) Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1. Neurosci. Lett., 430, 13-17.
    • (2008) Neurosci. Lett. , vol.430 , pp. 13-17
    • Takatori, S.1    Ito, G.2    Iwatsubo, T.3
  • 9
    • 84876296881 scopus 로고    scopus 로고
    • Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    • 10.1038/ nature12043.
    • Sarraf, S.A., Raman, M., Guarani-Pereira, V., Sowa, M.E., Huttlin, E.L., Gygi, S.P. and Harper, J.W. (2013) Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature, 10.1038/ nature12043.
    • (2013) Nature
    • Sarraf, S.A.1    Raman, M.2    Guarani-Pereira, V.3    Sowa, M.E.4    Huttlin, E.L.5    Gygi, S.P.6    Harper, J.W.7
  • 11
    • 78649685455 scopus 로고    scopus 로고
    • Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
    • Jin, S.M., Lazarou, M.,Wang,C., Kane, L.A., Narendra, D.P. and Youle, R.J. (2010) Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J. Cell Biol., 191, 933-942.
    • (2010) J. Cell Biol. , vol.191 , pp. 933-942
    • Jin, S.M.1    Lazarou, M.2    Wang, C.3    Kane, L.A.4    Narendra, D.P.5    Youle, R.J.6
  • 13
    • 0942290437 scopus 로고    scopus 로고
    • In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death
    • Azoulay-Zohar, H., Israelson, A., Abu-Hamad, S. and Shoshan-Barmatz, V. (2004) In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem. J., 377, 347.
    • (2004) Biochem. J. , vol.377 , pp. 347
    • Azoulay-Zohar, H.1    Israelson, A.2    Abu-Hamad, S.3    Shoshan-Barmatz, V.4
  • 14
    • 39449114808 scopus 로고    scopus 로고
    • Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II
    • Miyamoto, S., Murphy, A.N. and Brown, J.H. (2008) Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II. Cell Death Differ., 15, 521-529.
    • (2008) Cell Death Differ. , vol.15 , pp. 521-529
    • Miyamoto, S.1    Murphy, A.N.2    Brown, J.H.3
  • 15
    • 0036510541 scopus 로고    scopus 로고
    • Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
    • Pastorino, J.G., Shulga, N. and Hoek, J.B. (2002) Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. J. Biol. Chem., 277, 7610-7618.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7610-7618
    • Pastorino, J.G.1    Shulga, N.2    Hoek, J.B.3
  • 16
    • 38549163731 scopus 로고    scopus 로고
    • Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II
    • Sun, L., Shukair, S., Naik, T.J., Moazed, F. and Ardehali, H. (2008) Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II. Mol. Cell. Biol., 28, 1007-1017.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1007-1017
    • Sun, L.1    Shukair, S.2    Naik, T.J.3    Moazed, F.4    Ardehali, H.5
  • 19
    • 0030058890 scopus 로고    scopus 로고
    • Functional organization of mammalian hexokinase II retention of catalytic and regulatory functions in both the NH2- and COOH-terminal halves
    • Ardehali, H., Yano, Y., Printz, R.L., Koch, S., Whitesell, R.R.,May,J.M. and Granner, D.K. (1996) Functional organization of mammalian hexokinase II retention of catalytic and regulatory functions in both the NH2- and COOH-terminal halves. J. Biol. Chem., 271, 1849-1852.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1849-1852
    • Ardehali, H.1    Yano, Y.2    Printz, R.L.3    Koch, S.4    Whitesell, R.R.5    May, J.M.6    Granner, D.K.7
  • 20
    • 84858701257 scopus 로고    scopus 로고
    • Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons
    • Cai, Q., Zakaria, H.M., Simone, A. and Sheng, Z.-H. (2012) Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons. Curr. Biol., 22, 545-552.
    • (2012) Curr. Biol. , vol.22 , pp. 545-552
    • Cai, Q.1    Zakaria, H.M.2    Simone, A.3    Sheng, Z.-H.4
  • 22
    • 79551603345 scopus 로고    scopus 로고
    • Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
    • Van Laar, V.S., Arnold, B., Cassady, S.J., Chu, C.T., Burton, E.A. and Berman, S.B. (2011) Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum. Mol. Genet., 20, 927-940.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 927-940
    • Van Laar, V.S.1    Arnold, B.2    Cassady, S.J.3    Chu, C.T.4    Burton, E.A.5    Berman, S.B.6
  • 23
    • 67650655625 scopus 로고    scopus 로고
    • Mitochondrial matters of the heart: a plethora of regulatory modes to maintain function for a long lifetime
    • Pedersen, P.L. (2009) Mitochondrial matters of the heart: a plethora of regulatory modes to maintain function for a long lifetime. J. Bioenerg. Biomembr., 41, 95-98.
    • (2009) J. Bioenerg. Biomembr. , vol.41 , pp. 95-98
    • Pedersen, P.L.1
  • 24
    • 84870918602 scopus 로고    scopus 로고
    • Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
    • USA
    • Cheung, E.C., Ludwig, R.L. and Vousden, K.H. (2012) Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death. Proc. Natl Acad. Sci. USA, 109, 20491-20496.
    • (2012) Proc. Natl Acad. Sci. , vol.109 , pp. 20491-20496
    • Cheung, E.C.1    Ludwig, R.L.2    Vousden, K.H.3
  • 25
    • 79951699777 scopus 로고    scopus 로고
    • Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme
    • Wolf, A., Agnihotri, S., Micallef, J., Mukherjee, J., Sabha, N., Cairns, R., Hawkins, C. and Guha, A. (2011) Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme. J. Exp. Med., 208, 313-326.
    • (2011) J. Exp. Med. , vol.208 , pp. 313-326
    • Wolf, A.1    Agnihotri, S.2    Micallef, J.3    Mukherjee, J.4    Sabha, N.5    Cairns, R.6    Hawkins, C.7    Guha, A.8
  • 26
    • 59149095449 scopus 로고    scopus 로고
    • Mitochondrial hexokinase II promotes neuronal survival and acts downstream of glycogen synthase kinase-3
    • Gimenez-Cassina, A., Lim, F., Cerrato, T., Palomo, G.M. and Diaz-Nido, J. (2009) Mitochondrial hexokinase II promotes neuronal survival and acts downstream of glycogen synthase kinase-3. J. Biol. Chem., 284, 3001-3011.
    • (2009) J. Biol. Chem. , vol.284 , pp. 3001-3011
    • Gimenez-Cassina, A.1    Lim, F.2    Cerrato, T.3    Palomo, G.M.4    Diaz-Nido, J.5
  • 27
    • 28544436922 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity
    • Pastorino, J.G., Hoek, J.B. and Shulga, N. (2005) Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity. Cancer Res., 65, 10545-10554.
    • (2005) Cancer Res. , vol.65 , pp. 10545-10554
    • Pastorino, J.G.1    Hoek, J.B.2    Shulga, N.3
  • 30
    • 77951181836 scopus 로고    scopus 로고
    • PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
    • Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C.A., Sou, Y.S., Saiki, S., Kawajiri, S., Sato, F. et al. (2010) PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol., 189, 211-221.
    • (2010) J. Cell Biol. , vol.189 , pp. 211-221
    • Matsuda, N.1    Sato, S.2    Shiba, K.3    Okatsu, K.4    Saisho, K.5    Gautier, C.A.6    Sou, Y.S.7    Saiki, S.8    Kawajiri, S.9    Sato, F.10
  • 32
    • 78650116597 scopus 로고    scopus 로고
    • Post-translational modifications of mitochondrial outer membrane proteins
    • Kerner, J., Lee, K. and Hoppel, C.L. (2011) Post-translational modifications of mitochondrial outer membrane proteins. Free Radic. Res., 45, 16-28.
    • (2011) Free Radic. Res. , vol.45 , pp. 16-28
    • Kerner, J.1    Lee, K.2    Hoppel, C.L.3
  • 33
    • 58149395816 scopus 로고    scopus 로고
    • RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation
    • Malagelada, C., Jin, Z.H. and Greene, L.A. (2008) RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. J. Neurosci., 28, 14363-14371.
    • (2008) J. Neurosci. , vol.28 , pp. 14363-14371
    • Malagelada, C.1    Jin, Z.H.2    Greene, L.A.3
  • 34
    • 70350347175 scopus 로고    scopus 로고
    • Akt signal transduction dysfunction in Parkinson's disease
    • Timmons, S., Coakley, M.F., Moloney, A.M. and O'Neill, C. (2009) Akt signal transduction dysfunction in Parkinson's disease. Neurosci. Lett., 467, 30-35.
    • (2009) Neurosci. Lett. , vol.467 , pp. 30-35
    • Timmons, S.1    Coakley, M.F.2    Moloney, A.M.3    O'Neill, C.4
  • 35
    • 81955160695 scopus 로고    scopus 로고
    • PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis
    • Akundi, R.S., Zhi, L. and Büeler, H. (2012) PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis. Neurobiol. Dis., 45, 469-478.
    • (2012) Neurobiol. Dis. , vol.45 , pp. 469-478
    • Akundi, R.S.1    Zhi, L.2    Büeler, H.3
  • 37
    • 84882321254 scopus 로고    scopus 로고
    • Akt phosphorylates HK-II at Thr473 and increases mitochondrial HK-II association to protect cardiomyocytes
    • 10.1074/ jbc.M113.482026.
    • Roberts, D.J., Tan-Sah, V.P., Smith, J.M. and Miyamoto, S. (2013) Akt phosphorylates HK-II at Thr473 and increases mitochondrial HK-II association to protect cardiomyocytes. J. Biol. Chem., 10.1074/ jbc.M113.482026.
    • (2013) J. Biol. Chem.
    • Roberts, D.J.1    Tan-Sah, V.P.2    Smith, J.M.3    Miyamoto, S.4
  • 38
    • 84884286745 scopus 로고    scopus 로고
    • Shared and cell type-specific mitochondrial defects and metabolic adaptations in primary cells from PINK1-deficient mice
    • 10.1159/000345689.
    • Akundi, R.S., Zhi, L., Sullivan, P.G. and Büeler, H. (2012) Shared and cell type-specific mitochondrial defects and metabolic adaptations in primary cells from PINK1-deficient mice. Neurodegener. Dis., 10.1159/000345689.
    • (2012) Neurodegener. Dis.
    • Akundi, R.S.1    Zhi, L.2    Sullivan, P.G.3    Büeler, H.4
  • 40
    • 84856929845 scopus 로고    scopus 로고
    • Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease
    • Yao, Z., Gandhi, S., Burchell, V.S., Plun-Favreau, H., Wood, N.W. and Abramov, A.Y. (2011) Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease. J. Cell Sci., 124, 4194-4202.
    • (2011) J. Cell Sci. , vol.124 , pp. 4194-4202
    • Yao, Z.1    Gandhi, S.2    Burchell, V.S.3    Plun-Favreau, H.4    Wood, N.W.5    Abramov, A.Y.6
  • 42
    • 78649463381 scopus 로고    scopus 로고
    • Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
    • Gegg, M.E., Cooper, J.M., Chau, K.-Y., Rojo, M., Schapira, A.H.V. and Taanman, J.-W. (2010) Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum. Mol. Genet., 19, 4861-4870.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 4861-4870
    • Gegg, M.E.1    Cooper, J.M.2    Chau, K.-Y.3    Rojo, M.4    Schapira, A.H.V.5    Taanman, J.-W.6
  • 43
    • 77950384477 scopus 로고    scopus 로고
    • Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
    • USA
    • Ziviani, E., Tao, R.N. and Whitworth, A.J. (2010) Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc. Natl Acad. Sci. USA, 107, 5018-5023.
    • (2010) Proc. Natl Acad. Sci. , vol.107 , pp. 5018-5023
    • Ziviani, E.1    Tao, R.N.2    Whitworth, A.J.3
  • 44
    • 0035212435 scopus 로고    scopus 로고
    • Glycolysis in neurons, not astrocytes, delays oxidative metabolism of human visual cortex during sustained checkerboard stimulation in vivo
    • Gjedde,A. andMarrett, S. (2001)Glycolysis in neurons, not astrocytes, delays oxidative metabolism of human visual cortex during sustained checkerboard stimulation in vivo. J. Cereb. Blood Flow Metab., 21, 1384-1392.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 1384-1392
    • Gjedde, A.1    Marrett, S.2
  • 46
    • 77649328234 scopus 로고    scopus 로고
    • The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation
    • Kumar, A., Greggio, E., Beilina, A., Kaganovich, A., Chan, D., Taymans, J.-M., Wolozin, B. and Cookson, M.R. (2010) The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. PLoS One, 5, e8730.
    • (2010) PLoS One , vol.5
    • Kumar, A.1    Greggio, E.2    Beilina, A.3    Kaganovich, A.4    Chan, D.5    Taymans, J.-M.6    Wolozin, B.7    Cookson, M.R.8
  • 47
    • 34247351646 scopus 로고    scopus 로고
    • High Ca2+-phosphate transfection efficiency in low-density neuronal cultures
    • Jiang,M.and Chen, G. (2006) High Ca2+-phosphate transfection efficiency in low-density neuronal cultures. Nat. Protoc., 1, 695-700.
    • (2006) Nat. Protoc. , vol.1 , pp. 695-700
    • Jiang, M.1    Chen, G.2


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