Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Siddall, Hilary K ^a   Yellon, Derek M ^a   Ong, Sang Bing ^b   Mukherjee, Uma A ^a   Burke, Niall ^a   Hall, Andrew R ^a   Angelova, Plamena R ^a   Ludtmann, Marthe H R ^a   Deas, Emma ^a   Davidson, Sean M ^a   Mocanu, Mihaela M ^a   Hausenloy, Derek J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITI TEKNOLOGI MALAYSIA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN KINASE; PTEN INDUCIBLE KINASE 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; OXYGEN; PTEN-INDUCED PUTATIVE KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISOLATED HEART; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN TARGETING; REPERFUSION INJURY; SIMULATION; ANIMAL; CELL LINE; DEFICIENCY; ENZYMOLOGY; GENE INACTIVATION; GENETICS; HEART MUSCLE; METABOLISM; MITOCHONDRION; PATHOLOGY;

MUS;

ANIMALS; CELL LINE; DISEASE SUSCEPTIBILITY; GENE KNOCKOUT TECHNIQUES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDATIVE STRESS; OXYGEN; PROTEIN KINASES; REPERFUSION INJURY;

EID: 84876889535     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062400     Document Type: Article

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