-
1
-
-
24344500211
-
Initial sequence of the chimpanzee genome and comparison with the human genome
-
Chimpanzee Sequencing and Analysis Consortium 10.1038/nature04072
-
Chimpanzee Sequencing and Analysis Consortium. (2005). Initial sequence of the chimpanzee genome and comparison with the human genome. Nature, 437, 69-87.
-
(2005)
Nature
, vol.437
, pp. 69-87
-
-
-
2
-
-
84890310117
-
-
(eds) 3 Columbia University Press New York
-
Dobzhansky, T. (Ed.). (1951). Genetics and the origin of species (3rd ed., pp. 73-118). New York: Columbia University Press.
-
(1951)
Genetics and the Origin of Species
, pp. 73-118
-
-
Dobzhansky, T.1
-
3
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
21376230 10.1016/j.cell.2011.02.013 1:CAS:528:DC%2BC3MXjsFeqtrk%3D
-
Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
0034614637
-
The hallmarks of cancer
-
10647931 10.1016/S0092-8674(00)81683-9 1:CAS:528:DC%2BD3cXks1CktA%3D%3D
-
Hanahan, D., & Weinberg, R. A. (2000). The hallmarks of cancer. Cell, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
68849129170
-
A strategy for constructing aneuploid yeast strains by transient nondisjunction of a target chromosome
-
19594932 10.1186/1471-2156-10-36
-
Anders, K., Kudrna, J., Keller, K., Kinghorn, B., Miller, E., et al. (2009). A strategy for constructing aneuploid yeast strains by transient nondisjunction of a target chromosome. BMC Genetics, 10, 36.
-
(2009)
BMC Genetics
, vol.10
, pp. 36
-
-
Anders, K.1
Kudrna, J.2
Keller, K.3
Kinghorn, B.4
Miller, E.5
-
6
-
-
34548131710
-
Effects of aneuploidy on cellular physiology and cell division in haploid yeast
-
17702937 10.1126/science.1142210 1:CAS:528:DC%2BD2sXptVaisro%3D
-
Torres, E. M., Sokolsky, T., Tucker, C. M., Chan, L. Y., Boselli, M., et al. (2007). Effects of aneuploidy on cellular physiology and cell division in haploid yeast. Science, 317, 916-924.
-
(2007)
Science
, vol.317
, pp. 916-924
-
-
Torres, E.M.1
Sokolsky, T.2
Tucker, C.M.3
Chan, L.Y.4
Boselli, M.5
-
7
-
-
33751339726
-
Molecular-genetic biodiversity in a natural population of the yeast Saccharomyces cerevisiae from "evolution Canyon": Microsatellite polymorphism, ploidy and controversial sexual status
-
16980391 10.1534/genetics.106.062745 1:CAS:528:DC%2BD2sXktlCntQ%3D%3D
-
Ezov, T. K., Boger-Nadjar, E., Frenkel, Z., Katsperovski, I., Kemeny, S., et al. (2006). Molecular-genetic biodiversity in a natural population of the yeast Saccharomyces cerevisiae from "Evolution Canyon": microsatellite polymorphism, ploidy and controversial sexual status. Genetics, 174, 1455-1468.
-
(2006)
Genetics
, vol.174
, pp. 1455-1468
-
-
Ezov, T.K.1
Boger-Nadjar, E.2
Frenkel, Z.3
Katsperovski, I.4
Kemeny, S.5
-
8
-
-
17444446946
-
Widespread aneuploidy revealed by DNA microarray expression profiling
-
Hughes T. R., Roberts C. J., Dai H., Jones A. R., Meyer M. R., et al. (2000). Widespread aneuploidy revealed by DNA microarray expression profiling. Nat Genet, 25, 333-337.
-
(2000)
Nat Genet
, vol.25
, pp. 333-337
-
-
Hughes, T.R.1
Roberts, C.J.2
Dai, H.3
Jones, A.R.4
Meyer, M.R.5
-
9
-
-
0014923955
-
The tolerance of aneuploidy in yeast
-
5512257 10.1017/S0016672300002597 1:STN:280:DyaE3M3ltVeqsQ%3D%3D
-
Parry, E. M., & Cox, B. S. (1970). The tolerance of aneuploidy in yeast. Genetical Research, 16, 333-340.
-
(1970)
Genetical Research
, vol.16
, pp. 333-340
-
-
Parry, E.M.1
Cox, B.S.2
-
10
-
-
0019579741
-
Differential mitotic stability of yeast disomes derived from triploid meiosis
-
7035289 1:CAS:528:DyaL3MXmtFOmt7g%3D
-
Campbell, D., Doctor, J. S., Feuersanger, J. H., & Doolittle, M. M. (1981). Differential mitotic stability of yeast disomes derived from triploid meiosis. Genetics, 98, 239-255.
-
(1981)
Genetics
, vol.98
, pp. 239-255
-
-
Campbell, D.1
Doctor, J.S.2
Feuersanger, J.H.3
Doolittle, M.M.4
-
11
-
-
78149464968
-
Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae
-
10.1534/genetics.110.121533
-
Charles, J. S., Hamilton, M. L., & Petes, T. D. (2010). Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. Genetics, 186, 537-550.
-
(2010)
Genetics
, vol.186
, pp. 537-550
-
-
Charles, J.S.1
Hamilton, M.L.2
Petes, T.D.3
-
12
-
-
78149423336
-
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
-
20962780 10.1038/nature09529 1:CAS:528:DC%2BC3cXhtlWmu7vM
-
Pavelka, N., Rancati, G., Zhu, J., Bradford, W. D., Saraf, A., et al. (2010). Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast. Nature, 468, 321-325.
-
(2010)
Nature
, vol.468
, pp. 321-325
-
-
Pavelka, N.1
Rancati, G.2
Zhu, J.3
Bradford, W.D.4
Saraf, A.5
-
13
-
-
80051871652
-
Aneuploidy drives genomic instability in yeast
-
21852501 10.1126/science.1206412 1:CAS:528:DC%2BC3MXhtVWrtr7F
-
Sheltzer, J. M., Blank, H. M., Pfau, S. J., Tange, Y., George, B. M., et al. (2011). Aneuploidy drives genomic instability in yeast. Science, 333, 1026-1030.
-
(2011)
Science
, vol.333
, pp. 1026-1030
-
-
Sheltzer, J.M.1
Blank, H.M.2
Pfau, S.J.3
Tange, Y.4
George, B.M.5
-
14
-
-
22944471146
-
Differential chromosome control of ploidy in the yeast Saccharomyces cerevisiae
-
16034824 10.1002/yea.1226 1:CAS:528:DC%2BD2MXnt1Oqtro%3D
-
Waghmare, S. K., & Bruschi, C. V. (2005). Differential chromosome control of ploidy in the yeast Saccharomyces cerevisiae. Yeast, 22, 625-639.
-
(2005)
Yeast
, vol.22
, pp. 625-639
-
-
Waghmare, S.K.1
Bruschi, C.V.2
-
15
-
-
0036227470
-
Chromosome v loss due to centromere knockout or MAD2-deletion is immediately followed by restitution of homozygous diploidy in Saccharomyces cerevisiae
-
11921104 10.1002/yea.859 1:CAS:528:DC%2BD38Xjt1eis7Y%3D
-
Zang, Y., Garrè, M., Gjuracic, K., & Bruschi, C. V. (2002). Chromosome V loss due to centromere knockout or MAD2-deletion is immediately followed by restitution of homozygous diploidy in Saccharomyces cerevisiae. Yeast, 19, 553-564.
-
(2002)
Yeast
, vol.19
, pp. 553-564
-
-
Zang, Y.1
Garrè, M.2
Gjuracic, K.3
Bruschi, C.V.4
-
16
-
-
84863691442
-
Karyotypic determinants of chromosome instability in aneuploid budding yeast
-
22615582 10.1371/journal.pgen.1002719 1:CAS:528:DC%2BC38XnvFShtrY%3D
-
Zhu, J., Pavelka, N., Bradford, W. D., Rancati, G., & Li, R. (2012). Karyotypic determinants of chromosome instability in aneuploid budding yeast. PLoS Genetics, 8, e1002719.
-
(2012)
PLoS Genetics
, vol.8
, pp. 1002719
-
-
Zhu, J.1
Pavelka, N.2
Bradford, W.D.3
Rancati, G.4
Li, R.5
-
18
-
-
0030238423
-
Structural instability of a transgene locus in tobacco is associated with aneuploidy
-
8811861 10.1046/j.1365-313X.1996.10030469.x 1:CAS:528:DyaK28XmtF2lt74%3D
-
Papp, I., Iglesias, V. A., Moscone, E. A., Michalowski, S., Spiker, S., et al. (1996). Structural instability of a transgene locus in tobacco is associated with aneuploidy. The Plant Journal, 10, 469-478.
-
(1996)
The Plant Journal
, vol.10
, pp. 469-478
-
-
Papp, I.1
Iglesias, V.A.2
Moscone, E.A.3
Michalowski, S.4
Spiker, S.5
-
19
-
-
0033153475
-
Mouse autosomal trisomy: Two's company, three's a crowd
-
10354585 10.1016/S0168-9525(99)01743-6 1:CAS:528:DyaK1MXjvVGqtbw%3D
-
Hernandez, D., & Fisher, E. M. (1999). Mouse autosomal trisomy: two's company, three's a crowd. Trends in Genetics, 15, 241-247.
-
(1999)
Trends in Genetics
, vol.15
, pp. 241-247
-
-
Hernandez, D.1
Fisher, E.M.2
-
20
-
-
79954600431
-
Sporadic aneuploidy in PHA-stimulated lymphocytes of trisomies 21, 18, and 13
-
21252489 10.1159/000323504 1:STN:280:DC%2BC3MvivFSjsg%3D%3D
-
Reish, O., Regev, M., Kanesky, A., Girafi, S., & Mashevich, M. (2011). Sporadic aneuploidy in PHA-stimulated lymphocytes of trisomies 21, 18, and 13. Cytogenetic and Genome Research, 133, 184-189.
-
(2011)
Cytogenetic and Genome Research
, vol.133
, pp. 184-189
-
-
Reish, O.1
Regev, M.2
Kanesky, A.3
Girafi, S.4
Mashevich, M.5
-
21
-
-
33745745310
-
Sporadic aneuploidy in PHA-stimulated lymphocytes of Turner's syndrome patients
-
16823615 10.1007/s10577-006-1050-9 1:CAS:528:DC%2BD28XmsFOmu7Y%3D
-
Reish, O., Brosh, N., Gobazov, R., Rosenblat, M., Libman, V., et al. (2006). Sporadic aneuploidy in PHA-stimulated lymphocytes of Turner's syndrome patients. Chromosome Research, 14, 527-534.
-
(2006)
Chromosome Research
, vol.14
, pp. 527-534
-
-
Reish, O.1
Brosh, N.2
Gobazov, R.3
Rosenblat, M.4
Libman, V.5
-
22
-
-
83255185464
-
Myeloid leukemia in Down syndrome
-
22150305 10.1615/CritRevOncog.v16.i1-2.40
-
Khan, I., Malinge, S., & Crispino, J. (2011). Myeloid leukemia in Down syndrome. Critical Reviews in Oncogenesis, 16, 25-36.
-
(2011)
Critical Reviews in Oncogenesis
, vol.16
, pp. 25-36
-
-
Khan, I.1
Malinge, S.2
Crispino, J.3
-
23
-
-
40749104900
-
Cancer incidence in women with Turner syndrome in Great Britain: A national cohort study
-
18282803 10.1016/S1470-2045(08)70033-0
-
Schoemaker, M. J., Swerdlow, A. J., Higgins, C. D., Wright, A. F., & Jacobs, P. A. (2008). Cancer incidence in women with Turner syndrome in Great Britain: a national cohort study. The Lancet Oncology, 9, 239-246.
-
(2008)
The Lancet Oncology
, vol.9
, pp. 239-246
-
-
Schoemaker, M.J.1
Swerdlow, A.J.2
Higgins, C.D.3
Wright, A.F.4
Jacobs, P.A.5
-
24
-
-
23844435408
-
Cancer incidence and mortality in men with Klinefelter syndrome: A cohort study
-
16106025 10.1093/jnci/dji240
-
Swerdlow, A. J., Schoemaker, M. J., Higgins, C. D., Wright, A. F., & Jacobs, P. A. (2005). Cancer incidence and mortality in men with Klinefelter syndrome: a cohort study. Journal of the National Cancer Institute, 97, 1204-1210.
-
(2005)
Journal of the National Cancer Institute
, vol.97
, pp. 1204-1210
-
-
Swerdlow, A.J.1
Schoemaker, M.J.2
Higgins, C.D.3
Wright, A.F.4
Jacobs, P.A.5
-
25
-
-
34250344874
-
Mortality and cancer incidence in males with y polysomy in Britain: A cohort study
-
17457613 10.1007/s00439-007-0365-8
-
Higgins, C. D., Swerdlow, A. J., Schoemaker, M. J., Wright, A. F., & Jacobs, P. A. (2007). Mortality and cancer incidence in males with Y polysomy in Britain: a cohort study. Human Genetics, 121, 691-696.
-
(2007)
Human Genetics
, vol.121
, pp. 691-696
-
-
Higgins, C.D.1
Swerdlow, A.J.2
Schoemaker, M.J.3
Wright, A.F.4
Jacobs, P.A.5
-
26
-
-
0025033233
-
Microcell-mediated chromosome transfer: A strategy for studying the genetics and molecular pathology of human hereditary diseases with abnormal responses to DNA damage
-
2183771 1:STN:280:DyaK3c3is1ajug%3D%3D
-
Friedberg, E. C., Henning, K., Lambert, C., Saxon, P. J., Schultz, R. A., et al. (1990). Microcell-mediated chromosome transfer: a strategy for studying the genetics and molecular pathology of human hereditary diseases with abnormal responses to DNA damage. Basic Life Sciences, 52, 257-267.
-
(1990)
Basic Life Sciences
, vol.52
, pp. 257-267
-
-
Friedberg, E.C.1
Henning, K.2
Lambert, C.3
Saxon, P.J.4
Schultz, R.A.5
-
27
-
-
80053300903
-
Dysregulation of gene expression in the artificial human trisomy cells of chromosome 8 associated with transformed cell phenotypes
-
21980425 10.1371/journal.pone.0025319 1:CAS:528:DC%2BC3MXhtlGmtrfM
-
Nawata, H., Kashino, G., Tano, K., Daino, K., Shimada, Y., et al. (2011). Dysregulation of gene expression in the artificial human trisomy cells of chromosome 8 associated with transformed cell phenotypes. PLoS One, 6, e25319.
-
(2011)
PLoS One
, vol.6
, pp. 25319
-
-
Nawata, H.1
Kashino, G.2
Tano, K.3
Daino, K.4
Shimada, Y.5
-
28
-
-
3142615823
-
Microcell-mediated chromosome transfer provides evidence that polysomy promotes structural instability in tumor cell chromosomes through asynchronous replication and breakage within late-replicating regions
-
10.1002/gcc.20054 1:CAS:528:DC%2BD2cXmsVSgtLc%3D
-
Kost-Alimova, M., Fedorova, L., Yang, Y., Klein, G., & Imreh, S. (2004). Microcell-mediated chromosome transfer provides evidence that polysomy promotes structural instability in tumor cell chromosomes through asynchronous replication and breakage within late-replicating regions. Genes, Chromosomes & Cancer, 40, 316-324.
-
(2004)
Genes, Chromosomes & Cancer
, vol.40
, pp. 316-324
-
-
Kost-Alimova, M.1
Fedorova, L.2
Yang, Y.3
Klein, G.4
Imreh, S.5
-
29
-
-
76349126361
-
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
-
20123995 10.1083/jcb.200905057 1:CAS:528:DC%2BC3cXitVahs7k%3D
-
Thompson, S. L., & Compton, D. A. (2010). Proliferation of aneuploid human cells is limited by a p53-dependent mechanism. The Journal of Cell Biology, 188, 369-381.
-
(2010)
The Journal of Cell Biology
, vol.188
, pp. 369-381
-
-
Thompson, S.L.1
Compton, D.A.2
-
30
-
-
4944234694
-
Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells
-
15466185 10.1158/0008-5472.CAN-04-0474 1:CAS:528:DC%2BD2cXotFals7g%3D
-
Upender, M. B., Habermann, J. K., McShane, L. M., Korn, E. L., Barrett, J. C., et al. (2004). Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells. Cancer Research, 64, 6941-6949.
-
(2004)
Cancer Research
, vol.64
, pp. 6941-6949
-
-
Upender, M.B.1
Habermann, J.K.2
McShane, L.M.3
Korn, E.L.4
Barrett, J.C.5
-
31
-
-
84868290476
-
Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
-
22968442 10.1038/msb.2012.40
-
Stingele, S., Stoehr, G., Peplowska, K., Cox, J., Mann, M., et al. (2012). Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells. Molecular Systems Biology, 8, 608.
-
(2012)
Molecular Systems Biology
, vol.8
, pp. 608
-
-
Stingele, S.1
Stoehr, G.2
Peplowska, K.3
Cox, J.4
Mann, M.5
-
32
-
-
55349112533
-
Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells
-
18974345 10.1126/science.1160058 1:CAS:528:DC%2BD1cXht12ltb7O
-
Williams, B. R., Prabhu, V. R., Hunter, K. E., Glazier, C. M., Whittaker, C. A., et al. (2008). Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells. Science, 322, 703-709.
-
(2008)
Science
, vol.322
, pp. 703-709
-
-
Williams, B.R.1
Prabhu, V.R.2
Hunter, K.E.3
Glazier, C.M.4
Whittaker, C.A.5
-
33
-
-
17444446946
-
Widespread aneuploidy revealed by DNA microarray expression profiling
-
10888885 10.1038/77116 1:CAS:528:DC%2BD3cXkvFKktrY%3D
-
Hughes, T. R., Roberts, C. J., Dai, H., Jones, A. R., Meyer, M. R., et al. (2000). Widespread aneuploidy revealed by DNA microarray expression profiling. Nature Genetics, 25, 333-337.
-
(2000)
Nature Genetics
, vol.25
, pp. 333-337
-
-
Hughes, T.R.1
Roberts, C.J.2
Dai, H.3
Jones, A.R.4
Meyer, M.R.5
-
34
-
-
56349088536
-
Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor
-
19041751 10.1016/j.cell.2008.09.039 1:CAS:528:DC%2BD1cXhsV2jtr%2FL
-
Rancati, G., Pavelka, N., Fleharty, B., Noll, A., Trimble, R., et al. (2008). Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor. Cell, 135, 879-893.
-
(2008)
Cell
, vol.135
, pp. 879-893
-
-
Rancati, G.1
Pavelka, N.2
Fleharty, B.3
Noll, A.4
Trimble, R.5
-
35
-
-
0037403505
-
Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain
-
12706104 10.1016/S0888-7543(03)00035-1 1:CAS:528:DC%2BD3sXivVCrtL0%3D
-
Mao, R., Zielke, C. L., Zielke, H. R., & Pevsner, J. (2003). Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain. Genomics, 81, 457-467.
-
(2003)
Genomics
, vol.81
, pp. 457-467
-
-
Mao, R.1
Zielke, C.L.2
Zielke, H.R.3
Pevsner, J.4
-
36
-
-
0037115492
-
Transcriptome analysis of human autosomal trisomy
-
12471051 10.1093/hmg/11.26.3249 1:CAS:528:DC%2BD38XpsFelsr4%3D
-
FitzPatrick, D. R., Ramsay, J., McGill, N. I., Shade, M., Carothers, A. D., et al. (2002). Transcriptome analysis of human autosomal trisomy. Human Molecular Genetics, 11, 3249-3256.
-
(2002)
Human Molecular Genetics
, vol.11
, pp. 3249-3256
-
-
Fitzpatrick, D.R.1
Ramsay, J.2
McGill, N.I.3
Shade, M.4
Carothers, A.D.5
-
37
-
-
34548264230
-
Classification of human chromosome 21 gene-expression variations in Down syndrome: Impact on disease phenotypes
-
17701894 10.1086/520000 1:STN:280:DC%2BD2svotlCksg%3D%3D
-
Ait Yahya-Graison, E., Aubert, J., Dauphinot, L., Rivals, I., Prieur, M., et al. (2007). Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes. American Journal of Human Genetics, 81, 475-491.
-
(2007)
American Journal of Human Genetics
, vol.81
, pp. 475-491
-
-
Ait Yahya-Graison, E.1
Aubert, J.2
Dauphinot, L.3
Rivals, I.4
Prieur, M.5
-
38
-
-
77957237291
-
Identification of aneuploidy-tolerating mutations
-
20850176 10.1016/j.cell.2010.08.038 1:CAS:528:DC%2BC3cXht1Cmu73E
-
Torres, E. M., Dephoure, N., Panneerselvam, A., Tucker, C. M., Whittaker, C. A., et al. (2010). Identification of aneuploidy-tolerating mutations. Cell, 143, 71-83.
-
(2010)
Cell
, vol.143
, pp. 71-83
-
-
Torres, E.M.1
Dephoure, N.2
Panneerselvam, A.3
Tucker, C.M.4
Whittaker, C.A.5
-
39
-
-
79960319131
-
Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosis
-
21593209 10.1091/mbc.E09-01-0029 1:CAS:528:DC%2BC3MXpslKkt7g%3D
-
Barnhart, E. L., Dorer, R. K., Murray, A. W., & Schuyler, S. C. (2011). Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosis. Molecular Biology of the Cell, 22, 2448-2457.
-
(2011)
Molecular Biology of the Cell
, vol.22
, pp. 2448-2457
-
-
Barnhart, E.L.1
Dorer, R.K.2
Murray, A.W.3
Schuyler, S.C.4
-
40
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
17426725 10.1038/nrm2163 1:CAS:528:DC%2BD2sXksFSjsr0%3D
-
Musacchio, A., & Salmon, E. D. (2007). The spindle-assembly checkpoint in space and time. Nature Reviews Molecular Cell Biology, 8, 379-393.
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
41
-
-
33846428426
-
Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice
-
17210695 10.1158/0008-5472.CAN-06-3326 1:CAS:528:DC%2BD2sXisFShtg%3D%3D
-
Iwanaga, Y., Chi, Y. H., Miyazato, A., Sheleg, S., Haller, K., et al. (2007). Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. Cancer Research, 67, 160-166.
-
(2007)
Cancer Research
, vol.67
, pp. 160-166
-
-
Iwanaga, Y.1
Chi, Y.H.2
Miyazato, A.3
Sheleg, S.4
Haller, K.5
-
42
-
-
77949773695
-
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
-
20173739 10.1038/nature08803 1:CAS:528:DC%2BC3cXit1SmtL0%3D
-
Sotillo, R., Schvartzman, J. M., Socci, N. D., & Benezra, R. (2010). Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal. Nature, 464, 436-440.
-
(2010)
Nature
, vol.464
, pp. 436-440
-
-
Sotillo, R.1
Schvartzman, J.M.2
Socci, N.D.3
Benezra, R.4
-
43
-
-
0042978646
-
Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
-
12925705 10.1083/jcb.200303167 1:CAS:528:DC%2BD3sXms1Sqtr0%3D
-
Weaver, B. A., Bonday, Z. Q., Putkey, F. R., Kops, G. J., Silk, A. D., et al. (2003). Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. The Journal of Cell Biology, 162, 551-563.
-
(2003)
The Journal of Cell Biology
, vol.162
, pp. 551-563
-
-
Weaver, B.A.1
Bonday, Z.Q.2
Putkey, F.R.3
Kops, G.J.4
Silk, A.D.5
-
44
-
-
70749158525
-
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity
-
19962666 10.1016/j.ccr.2009.10.023 1:CAS:528:DC%2BC3cXht1eqsbs%3D
-
Baker, D. J., Jin, F., Jeganathan, K. B., & van Deursen, J. M. (2009). Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell, 16, 475-486.
-
(2009)
Cancer Cell
, vol.16
, pp. 475-486
-
-
Baker, D.J.1
Jin, F.2
Jeganathan, K.B.3
Van Deursen, J.M.4
-
45
-
-
34247105784
-
Mutant mice with small amounts of BubR1 display accelerated age-related gliosis
-
16781018 10.1016/j.neurobiolaging.2006.05.012 1:CAS:528: DC%2BD2sXksFWnt7g%3D
-
Hartman, T. K., Wengenack, T. M., Poduslo, J. F., & van Deursen, J. M. (2007). Mutant mice with small amounts of BubR1 display accelerated age-related gliosis. Neurobiology of Aging, 28, 921-927.
-
(2007)
Neurobiology of Aging
, vol.28
, pp. 921-927
-
-
Hartman, T.K.1
Wengenack, T.M.2
Poduslo, J.F.3
Van Deursen, J.M.4
-
46
-
-
32644435114
-
Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice
-
16476774 10.1083/jcb.200507081 1:CAS:528:DC%2BD28XhsFKgtro%3D
-
Baker, D. J., Jeganathan, K. B., Malureanu, L., Perez-Terzic, C., Terzic, A., et al. (2006). Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice. The Journal of Cell Biology, 172, 529-540.
-
(2006)
The Journal of Cell Biology
, vol.172
, pp. 529-540
-
-
Baker, D.J.1
Jeganathan, K.B.2
Malureanu, L.3
Perez-Terzic, C.4
Terzic, A.5
-
47
-
-
59349098193
-
The consequences of tetraploidy and aneuploidy
-
19020304 10.1242/jcs.039537 1:CAS:528:DC%2BD1MXptFWntA%3D%3D
-
Storchova, Z., & Kuffer, C. (2008). The consequences of tetraploidy and aneuploidy. Journal of Cell Science, 121, 3859-3866.
-
(2008)
Journal of Cell Science
, vol.121
, pp. 3859-3866
-
-
Storchova, Z.1
Kuffer, C.2
-
48
-
-
84865156842
-
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons
-
22778409 10.1073/pnas.1201911109 1:CAS:528:DC%2BC38XhsVamt73L
-
Ryan, S. D., Britigan, E. M., Zasadil, L. M., Witte, K., Audhya, A., et al. (2012). Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons. Proceedings of the National Academy of Sciences of the United States of America, 109, E2205-E2214.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
-
-
Ryan, S.D.1
Britigan, E.M.2
Zasadil, L.M.3
Witte, K.4
Audhya, A.5
-
49
-
-
33845986330
-
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
-
17189715 10.1016/j.ccr.2006.10.019 1:CAS:528:DC%2BD2sXhtFKmt74%3D
-
Sotillo, R., Hernando, E., Diaz-Rodriguez, E., Teruya-Feldstein, J., Cordon-Cardo, C., et al. (2007). Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell, 11, 9-23.
-
(2007)
Cancer Cell
, vol.11
, pp. 9-23
-
-
Sotillo, R.1
Hernando, E.2
Diaz-Rodriguez, E.3
Teruya-Feldstein, J.4
Cordon-Cardo, C.5
-
50
-
-
79959416796
-
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
-
21646403 10.1083/jcb.201012035 1:CAS:528:DC%2BC3MXnvFWqu7k%3D
-
Ricke, R. M., Jeganathan, K. B., & van Deursen, J. M. (2011). Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. The Journal of Cell Biology, 193, 1049-1064.
-
(2011)
The Journal of Cell Biology
, vol.193
, pp. 1049-1064
-
-
Ricke, R.M.1
Jeganathan, K.B.2
Van Deursen, J.M.3
-
51
-
-
51349147655
-
Overexpression of Separase induces aneuploidy and mammary tumorigenesis
-
18728194 10.1073/pnas.0801610105 1:CAS:528:DC%2BD1cXhtFSmtrbP
-
Zhang, N., Ge, G., Meyer, R., Sethi, S., Basu, D., et al. (2008). Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 105, 13033-13038.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 13033-13038
-
-
Zhang, N.1
Ge, G.2
Meyer, R.3
Sethi, S.4
Basu, D.5
-
52
-
-
0242468471
-
Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells
-
12960092 10.1210/en.2003-0305 1:CAS:528:DC%2BD3sXosleru74%3D
-
Yu, R., Lu, W., Chen, J., McCabe, C. J., & Melmed, S. (2003). Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells. Endocrinology, 144, 4991-4998.
-
(2003)
Endocrinology
, vol.144
, pp. 4991-4998
-
-
Yu, R.1
Lu, W.2
Chen, J.3
McCabe, C.J.4
Melmed, S.5
-
53
-
-
79958733630
-
Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition
-
21665145 10.1016/j.ccr.2011.04.017 1:CAS:528:DC%2BC3MXnsVClu7w%3D
-
Schvartzman, J. M., Duijf, P. H., Sotillo, R., Coker, C., & Benezra, R. (2011). Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell, 19, 701-714.
-
(2011)
Cancer Cell
, vol.19
, pp. 701-714
-
-
Schvartzman, J.M.1
Duijf, P.H.2
Sotillo, R.3
Coker, C.4
Benezra, R.5
-
54
-
-
84859587548
-
Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells
-
22405866 10.1016/j.cub.2012.02.030 1:CAS:528:DC%2BC38XjsFKqsr8%3D
-
Kabeche, L., & Compton, D. A. (2012). Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells. Current Biology, 22, 638-644.
-
(2012)
Current Biology
, vol.22
, pp. 638-644
-
-
Kabeche, L.1
Compton, D.A.2
-
55
-
-
80655123645
-
Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation
-
22033440 10.4161/cc.10.21.18156 1:CAS:528:DC%2BC38XmsFejtA%3D%3D
-
Ricke, R. M., & van Deursen, J. M. (2011). Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation. Cell Cycle, 10, 3645-3651.
-
(2011)
Cell Cycle
, vol.10
, pp. 3645-3651
-
-
Ricke, R.M.1
Van Deursen, J.M.2
-
56
-
-
58149334818
-
Genome stability is ensured by temporal control of kinetochore- microtubule dynamics
-
19060894 10.1038/ncb1809 1:CAS:528:DC%2BD1MXhtVKjsA%3D%3D
-
Bakhoum, S. F., Thompson, S. L., Manning, A. L., & Compton, D. A. (2009). Genome stability is ensured by temporal control of kinetochore- microtubule dynamics. Nature Cell Biology, 11, 27-35.
-
(2009)
Nature Cell Biology
, vol.11
, pp. 27-35
-
-
Bakhoum, S.F.1
Thompson, S.L.2
Manning, A.L.3
Compton, D.A.4
-
57
-
-
1542373746
-
Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments
-
14699064 10.1091/mbc.E03-08-0581 1:CAS:528:DC%2BD2cXitlGgsr4%3D
-
Kline-Smith, S. L., Khodjakov, A., Hergert, P., & Walczak, C. E. (2004). Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments. Molecular Biology of the Cell, 15, 1146-1159.
-
(2004)
Molecular Biology of the Cell
, vol.15
, pp. 1146-1159
-
-
Kline-Smith, S.L.1
Khodjakov, A.2
Hergert, P.3
Walczak, C.E.4
-
58
-
-
80053364894
-
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
-
21960636 10.1126/science.1210214 1:CAS:528:DC%2BC3MXht1aitrzN
-
Janssen, A., van der Burg, M., Szuhai, K., Kops, G. J., & Medema, R. H. (2011). Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science, 333, 1895-1898.
-
(2011)
Science
, vol.333
, pp. 1895-1898
-
-
Janssen, A.1
Van Der Burg, M.2
Szuhai, K.3
Kops, G.J.4
Medema, R.H.5
-
59
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
22258507 10.1038/nature10802 1:CAS:528:DC%2BC38XhtVKjtrw%3D
-
Crasta, K., Ganem, N. J., Dagher, R., Lantermann, A. B., Ivanova, E. V., et al. (2012). DNA breaks and chromosome pulverization from errors in mitosis. Nature, 482, 53-58.
-
(2012)
Nature
, vol.482
, pp. 53-58
-
-
Crasta, K.1
Ganem, N.J.2
Dagher, R.3
Lantermann, A.B.4
Ivanova, E.V.5
-
60
-
-
34548037643
-
Mitotic cell death by chromosome fragmentation
-
17699772 10.1158/0008-5472.CAN-07-0472 1:CAS:528:DC%2BD2sXptVGlsb4%3D
-
Stevens, J. B., Liu, G., Bremer, S. W., Ye, K. J., Xu, W., et al. (2007). Mitotic cell death by chromosome fragmentation. Cancer Research, 67, 7686-7694.
-
(2007)
Cancer Research
, vol.67
, pp. 7686-7694
-
-
Stevens, J.B.1
Liu, G.2
Bremer, S.W.3
Ye, K.J.4
Xu, W.5
-
61
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
21215367 10.1016/j.cell.2010.11.055 1:CAS:528:DC%2BC3MXksFGjug%3D%3D
-
Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., et al. (2011). Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell, 144, 27-40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
Yang, F.4
Bignell, G.R.5
-
62
-
-
80053027921
-
Evolutionary mechanisms and diversity in cancer
-
21925306 10.1016/B978-0-12-387688-1.00008-9 1:CAS:528:DC%2BC38XhvV2ns7fL
-
Heng, H. H., Stevens, J. B., Bremer, S. W., Liu, G., Abdallah, B. Y., et al. (2011). Evolutionary mechanisms and diversity in cancer. Advances in Cancer Research, 112, 217-253.
-
(2011)
Advances in Cancer Research
, vol.112
, pp. 217-253
-
-
Heng, H.H.1
Stevens, J.B.2
Bremer, S.W.3
Liu, G.4
Abdallah, B.Y.5
-
63
-
-
77955907833
-
Understanding cytokinesis failure
-
20687468 10.1007/978-1-4419-6199-0-3 1:CAS:528:DC%2BC3cXhs1Wrsr3I
-
Normand, G., & King, R. W. (2010). Understanding cytokinesis failure. Advances in Experimental Medicine and Biology, 676, 27-55.
-
(2010)
Advances in Experimental Medicine and Biology
, vol.676
, pp. 27-55
-
-
Normand, G.1
King, R.W.2
-
64
-
-
27144518175
-
Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines
-
16222248 10.1038/nature03958 1:CAS:528:DC%2BD2MXhtV2ktrnO
-
Shi, Q., & King, R. W. (2005). Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. Nature, 437, 1038-1042.
-
(2005)
Nature
, vol.437
, pp. 1038-1042
-
-
Shi, Q.1
King, R.W.2
-
65
-
-
0035877638
-
Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p
-
11274158 10.1074/jbc.M101096200 1:CAS:528:DC%2BD3MXksFGks70%3D
-
Routhier, E. L., Burn, T. C., Abbaszade, I., Summers, M., Albright, C. F., et al. (2001). Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p. Journal of Biological Chemistry, 276, 21670-21677.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 21670-21677
-
-
Routhier, E.L.1
Burn, T.C.2
Abbaszade, I.3
Summers, M.4
Albright, C.F.5
-
66
-
-
33750610006
-
Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis
-
16950109 10.1016/j.cub.2006.07.020 1:CAS:528:DC%2BD28XptFSkt7c%3D
-
Kouranti, I., Sachse, M., Arouche, N., Goud, B., & Echard, A. (2006). Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis. Current Biology, 16, 1719-1725.
-
(2006)
Current Biology
, vol.16
, pp. 1719-1725
-
-
Kouranti, I.1
Sachse, M.2
Arouche, N.3
Goud, B.4
Echard, A.5
-
67
-
-
0032581530
-
Role of citron kinase as a target of the small GTPase Rho in cytokinesis
-
9697773 10.1038/28873 1:CAS:528:DyaK1cXltVGqtrs%3D
-
Madaule, P., Eda, M., Watanabe, N., Fujisawa, K., Matsuoka, T., et al. (1998). Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature, 394, 491-494.
-
(1998)
Nature
, vol.394
, pp. 491-494
-
-
Madaule, P.1
Eda, M.2
Watanabe, N.3
Fujisawa, K.4
Matsuoka, T.5
-
68
-
-
23944499922
-
An ECT2-centralspindlin complex regulates the localization and function of RhoA
-
16103226 10.1083/jcb.200501097
-
Yuce, O., Piekny, A., & Glotzer, M. (2005). An ECT2-centralspindlin complex regulates the localization and function of RhoA. The Journal of Cell Biology, 170, 571-582.
-
(2005)
The Journal of Cell Biology
, vol.170
, pp. 571-582
-
-
Yuce, O.1
Piekny, A.2
Glotzer, M.3
-
69
-
-
0022587338
-
Dicentric chromosomes and the inactivation of the centromere
-
3456974 10.1007/BF00291876 1:STN:280:DyaL287ms1CrtQ%3D%3D
-
Therman, E., Trunca, C., Kuhn, E. M., & Sarto, G. E. (1986). Dicentric chromosomes and the inactivation of the centromere. Human Genetics, 72, 191-195.
-
(1986)
Human Genetics
, vol.72
, pp. 191-195
-
-
Therman, E.1
Trunca, C.2
Kuhn, E.M.3
Sarto, G.E.4
-
70
-
-
34247505472
-
DNA repair pathways involved in anaphase bridge formation
-
10.1002/gcc.20425 1:CAS:528:DC%2BD2sXkslGhsbg%3D
-
Acilan, C., Potter, D. M., & Saunders, W. S. (2007). DNA repair pathways involved in anaphase bridge formation. Genes, Chromosomes & Cancer, 46, 522-531.
-
(2007)
Genes, Chromosomes & Cancer
, vol.46
, pp. 522-531
-
-
Acilan, C.1
Potter, D.M.2
Saunders, W.S.3
-
71
-
-
59049101302
-
Aurora B-mediated abscission checkpoint protects against tetraploidization
-
19203582 10.1016/j.cell.2008.12.020
-
Steigemann, P., Wurzenberger, C., Schmitz, M. H., Held, M., Guizetti, J., et al. (2009). Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell, 136, 473-484.
-
(2009)
Cell
, vol.136
, pp. 473-484
-
-
Steigemann, P.1
Wurzenberger, C.2
Schmitz, M.H.3
Held, M.4
Guizetti, J.5
-
72
-
-
33751579138
-
Origins and consequences of centrosome aberrations in human cancers
-
10.1002/ijc.22245 1:CAS:528:DC%2BD28Xht1yqt7rE
-
Nigg, E. A. (2006). Origins and consequences of centrosome aberrations in human cancers. International Journal of Cancer, 119, 2717-2723.
-
(2006)
International Journal of Cancer
, vol.119
, pp. 2717-2723
-
-
Nigg, E.A.1
-
73
-
-
67649467032
-
A mechanism linking extra centrosomes to chromosomal instability
-
19506557 10.1038/nature08136 1:CAS:528:DC%2BD1MXntVWjtbs%3D
-
Ganem, N. J., Godinho, S. A., & Pellman, D. (2009). A mechanism linking extra centrosomes to chromosomal instability. Nature, 460, 278-282.
-
(2009)
Nature
, vol.460
, pp. 278-282
-
-
Ganem, N.J.1
Godinho, S.A.2
Pellman, D.3
-
74
-
-
68549096165
-
Centrosomes and cancer: How cancer cells divide with too many centrosomes
-
19156503 10.1007/s10555-008-9163-6 1:CAS:528:DC%2BD1MXjsVWntr0%3D
-
Godinho, S. A., Kwon, M., & Pellman, D. (2009). Centrosomes and cancer: how cancer cells divide with too many centrosomes. Cancer and Metastasis Reviews, 28, 85-98.
-
(2009)
Cancer and Metastasis Reviews
, vol.28
, pp. 85-98
-
-
Godinho, S.A.1
Kwon, M.2
Pellman, D.3
-
75
-
-
78650542319
-
Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis
-
21059955 10.1073/pnas.1006829107 1:CAS:528:DC%2BC3cXhsFWltLrF
-
Gisselsson, D., Jin, Y., Lindgren, D., Persson, J., Gisselsson, L., et al. (2010). Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis. Proceedings of the National Academy of Sciences of the United States of America, 107, 20489-20493.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 20489-20493
-
-
Gisselsson, D.1
Jin, Y.2
Lindgren, D.3
Persson, J.4
Gisselsson, L.5
-
76
-
-
50049085789
-
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
-
10.1101/gad.1700908 1:CAS:528:DC%2BD1cXhtVehtr3O
-
Kwon, M., Godinho, S. A., Chandhok, N. S., Ganem, N. J., Azioune, A., et al. (2008). Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes & Development, 22, 2189-2203.
-
(2008)
Genes & Development
, vol.22
, pp. 2189-2203
-
-
Kwon, M.1
Godinho, S.A.2
Chandhok, N.S.3
Ganem, N.J.4
Azioune, A.5
-
77
-
-
27144507868
-
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
-
16222300 10.1038/nature04217 1:CAS:528:DC%2BD2MXhtV2ktrnM
-
Fujiwara, T., Bandi, M., Nitta, M., Ivanova, E. V., Bronson, R. T., et al. (2005). Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature, 437, 1043-1047.
-
(2005)
Nature
, vol.437
, pp. 1043-1047
-
-
Fujiwara, T.1
Bandi, M.2
Nitta, M.3
Ivanova, E.V.4
Bronson, R.T.5
-
78
-
-
34047274772
-
Tetraploidy, aneuploidy and cancer
-
17324569 10.1016/j.gde.2007.02.011 1:CAS:528:DC%2BD2sXkt1ahs74%3D
-
Ganem, N. J., Storchova, Z., & Pellman, D. (2007). Tetraploidy, aneuploidy and cancer. Current Opinion in Genetics and Development, 17, 157-162.
-
(2007)
Current Opinion in Genetics and Development
, vol.17
, pp. 157-162
-
-
Ganem, N.J.1
Storchova, Z.2
Pellman, D.3
-
79
-
-
84860782006
-
Absolute quantification of somatic DNA alterations in human cancer
-
22544022 10.1038/nbt.2203 1:CAS:528:DC%2BC38Xmt1Gktb4%3D
-
Carter, S. L., Cibulskis, K., Helman, E., McKenna, A., Shen, H., et al. (2012). Absolute quantification of somatic DNA alterations in human cancer. Nature Biotechnology, 30, 413-421.
-
(2012)
Nature Biotechnology
, vol.30
, pp. 413-421
-
-
Carter, S.L.1
Cibulskis, K.2
Helman, E.3
McKenna, A.4
Shen, H.5
-
80
-
-
77958004840
-
The ploidy conveyor of mature hepatocytes as a source of genetic variation
-
20861837 10.1038/nature09414 1:CAS:528:DC%2BC3cXhtFynsbfL
-
Duncan, A. W., Taylor, M. H., Hickey, R. D., Hanlon Newell, A. E., Lenzi, M. L., et al. (2010). The ploidy conveyor of mature hepatocytes as a source of genetic variation. Nature, 467, 707-710.
-
(2010)
Nature
, vol.467
, pp. 707-710
-
-
Duncan, A.W.1
Taylor, M.H.2
Hickey, R.D.3
Hanlon Newell, A.E.4
Lenzi, M.L.5
-
81
-
-
83755169599
-
Frequent aneuploidy among normal human hepatocytes
-
22057114 10.1053/j.gastro.2011.10.029
-
Duncan, A. W., Hanlon Newell, A. E., Smith, L., Wilson, E. M., Olson, S. B., et al. (2012). Frequent aneuploidy among normal human hepatocytes. Gastroenterology, 142, 25-28.
-
(2012)
Gastroenterology
, vol.142
, pp. 25-28
-
-
Duncan, A.W.1
Hanlon Newell, A.E.2
Smith, L.3
Wilson, E.M.4
Olson, S.B.5
-
82
-
-
84866000846
-
Aneuploidy as a mechanism for stress-induced liver adaptation
-
22863619 10.1172/JCI64026 1:CAS:528:DC%2BC38XhtlChsbjJ
-
Duncan, A. W., Hanlon Newell, A. E., Bi, W., Finegold, M. J., Olson, S. B., et al. (2012). Aneuploidy as a mechanism for stress-induced liver adaptation. The Journal of Clinical Investigation, 122, 3307-3315.
-
(2012)
The Journal of Clinical Investigation
, vol.122
, pp. 3307-3315
-
-
Duncan, A.W.1
Hanlon Newell, A.E.2
Bi, W.3
Finegold, M.J.4
Olson, S.B.5
-
83
-
-
84862777815
-
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
-
22286062 1:CAS:528:DC%2BC38XhtlOrsr8%3D
-
Chen, G., Bradford, W. D., Seidel, C. W., & Li, R. (2012). Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy. Nature, 482, 246-250.
-
(2012)
Nature
, vol.482
, pp. 246-250
-
-
Chen, G.1
Bradford, W.D.2
Seidel, C.W.3
Li, R.4
-
84
-
-
0042166174
-
Chromosome aberrations in solid tumors
-
12923544 10.1038/ng1215 1:CAS:528:DC%2BD3sXmt1Skuro%3D
-
Albertson, D. G., Collins, C., McCormick, F., & Gray, J. W. (2003). Chromosome aberrations in solid tumors. Nature Genetics, 34, 369-376.
-
(2003)
Nature Genetics
, vol.34
, pp. 369-376
-
-
Albertson, D.G.1
Collins, C.2
McCormick, F.3
Gray, J.W.4
-
85
-
-
0032506125
-
Genetic instability of cancer cells is proportional to their degree of aneuploidy
-
9811862 10.1073/pnas.95.23.13692 1:CAS:528:DyaK1cXnsVGht7s%3D
-
Duesberg, P., Rausch, C., Rasnick, D., & Hehlmann, R. (1998). Genetic instability of cancer cells is proportional to their degree of aneuploidy. Proceedings of the National Academy of Sciences of the United States of America, 95, 13692-13697.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 13692-13697
-
-
Duesberg, P.1
Rausch, C.2
Rasnick, D.3
Hehlmann, R.4
-
86
-
-
84857192718
-
Causes and consequences of aneuploidy in cancer
-
22269907 1:CAS:528:DC%2BC38XhtFSnu7k%3D
-
Gordon, D. J., Resio, B., & Pellman, D. (2012). Causes and consequences of aneuploidy in cancer. Nature Reviews Genetics, 13, 189-203.
-
(2012)
Nature Reviews Genetics
, vol.13
, pp. 189-203
-
-
Gordon, D.J.1
Resio, B.2
Pellman, D.3
-
87
-
-
33846065784
-
Aneuploidy acts both oncogenically and as a tumor suppressor
-
17189716 10.1016/j.ccr.2006.12.003 1:CAS:528:DC%2BD2sXhtFClsLs%3D
-
Weaver, B. A., Silk, A. D., Montagna, C., Verdier-Pinard, P., & Cleveland, D. W. (2007). Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell, 11, 25-36.
-
(2007)
Cancer Cell
, vol.11
, pp. 25-36
-
-
Weaver, B.A.1
Silk, A.D.2
Montagna, C.3
Verdier-Pinard, P.4
Cleveland, D.W.5
-
88
-
-
80052186209
-
P53: Guardian of ploidy
-
21852209 10.1016/j.molonc.2011.07.007 1:CAS:528:DC%2BC3MXhtVyqtL7K
-
Aylon, Y., & Oren, M. (2011). p53: guardian of ploidy. Molecular Oncology, 5, 315-323.
-
(2011)
Molecular Oncology
, vol.5
, pp. 315-323
-
-
Aylon, Y.1
Oren, M.2
-
89
-
-
77955363995
-
TP53 mutations in human cancers: Origins, consequences, and clinical use
-
20182602 10.1101/cshperspect.a001008
-
Olivier, M., Hollstein, M., & Hainaut, P. (2010). TP53 mutations in human cancers: origins, consequences, and clinical use. Cold Spring Harbor Perspectives in Biology, 2, a001008.
-
(2010)
Cold Spring Harbor Perspectives in Biology
, vol.2
, pp. 001008
-
-
Olivier, M.1
Hollstein, M.2
Hainaut, P.3
-
90
-
-
70450270900
-
Awakening guardian angels: Drugging the p53 pathway
-
19935675 10.1038/nrc2763 1:CAS:528:DC%2BD1MXhsVGlur%2FM
-
Brown, C. J., Lain, S., Verma, C. S., Fersht, A. R., & Lane, D. P. (2009). Awakening guardian angels: drugging the p53 pathway. Nature Reviews. Cancer, 9, 862-873.
-
(2009)
Nature Reviews. Cancer
, vol.9
, pp. 862-873
-
-
Brown, C.J.1
Lain, S.2
Verma, C.S.3
Fersht, A.R.4
Lane, D.P.5
-
91
-
-
0034676455
-
Surfing the p53 network
-
11099028 10.1038/35042675 1:CAS:528:DC%2BD3cXosVemtrY%3D
-
Vogelstein, B., Lane, D., & Levine, A. J. (2000). Surfing the p53 network. Nature, 408, 307-310.
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
92
-
-
33847271089
-
Coping with stress: Multiple ways to activate p53
-
17322916 10.1038/sj.onc.1210263 1:CAS:528:DC%2BD2sXitVKhsLY%3D
-
Horn, H. F., & Vousden, K. H. (2007). Coping with stress: multiple ways to activate p53. Oncogene, 26, 1306-1316.
-
(2007)
Oncogene
, vol.26
, pp. 1306-1316
-
-
Horn, H.F.1
Vousden, K.H.2
-
94
-
-
79951689086
-
Identification of aneuploidy-selective antiproliferation compounds
-
21315436 10.1016/j.cell.2011.01.017 1:CAS:528:DC%2BC3MXit1Gqu7w%3D
-
Tang, Y. C., Williams, B. R., Siegel, J. J., & Amon, A. (2011). Identification of aneuploidy-selective antiproliferation compounds. Cell, 144, 499-512.
-
(2011)
Cell
, vol.144
, pp. 499-512
-
-
Tang, Y.C.1
Williams, B.R.2
Siegel, J.J.3
Amon, A.4
-
95
-
-
20044379205
-
Constitutional aneuploidy in the normal human brain
-
15745943 10.1523/JNEUROSCI.4560-04.2005 1:CAS:528:DC%2BD2MXisVOmtro%3D
-
Rehen, S. K., Yung, Y. C., McCreight, M. P., Kaushal, D., Yang, A. H., et al. (2005). Constitutional aneuploidy in the normal human brain. Journal of Neuroscience, 25, 2176-2180.
-
(2005)
Journal of Neuroscience
, vol.25
, pp. 2176-2180
-
-
Rehen, S.K.1
Yung, Y.C.2
McCreight, M.P.3
Kaushal, D.4
Yang, A.H.5
|