Mouse autosomal trisomy: Two's company, three's a crowd

Trends in Genetics

Volumn 15, Issue 6, 1999, Pages 241-247

  Hernandez, Diana ^a   Fisher, Elizabeth M C ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; AUTOSOME MOSAICISM; CHROMOSOME 16; CHROMOSOME 17; GENE ISOLATION; GENETIC ENGINEERING; GENETIC MANIPULATION; MOLECULAR GENETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYNDROME DELINEATION; TRISOMY;

ABORTION, SPONTANEOUS; ANIMALS; CROSSES, GENETIC; FEMALE; HUMANS; MALE; MICE; MODELS, GENETIC; PREGNANCY; SYNDROME; TRISOMY;

ANIMALIA; RODENTIA;

EID: 0033153475     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(99)01743-6     Document Type: Review

References (60)

1. Shaffer L.G.et al. Systematic search for uniparental disomy in early fetal losses: the results and a review of the literature. Am. J. Med. Genet. 79:1998;366-372.
2. Hernandez D., Fisher E.M.C. Down syndrome genetics: unravelling a multifactorial disorder. Hum. Mol. Genet. 5:1996;1411-1416.
3. Gearhart J.D.et al. Developmental consequences of autosomal aneuploidy in mammals. Dev. Genet. 8:1987;249-265.
4. Smith D.et al. Functional screening of 2Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome. Nat. Genet. 16:1997;28-36.
5. Gropp A.et al. Trisomy in the fetal backcross progeny of male and female metacentric heterozygotes of the mouse. I. Cytogenet. Cell Genet. 13:1974;511-535.
6. Gropp A.et al. Systematic approach to the study of trisomy in the mouse. II. Cytogenet. Cell Genet. 14:1975;42-62.
7. Epstein C. Genetic control of survival of murine trisomy 16 fetuses. Teratology. 42:1990;571-580.
8. Demczuk S., Vekemans M. Genetic analysis of the maternal factors controlling the survival of trisomy 16 mouse fetuses. Teratology. 47:1993;311-319.
9. Stubbs L.et al. Generation and characterization of heritable reciprocal translocations in mice. Methods. 13:1997;397-408.
10. Cattanach B.M.et al. Large deletions and other gross forms of chromosome imbalance compatible with viability and fertility in the mouse. Nat. Genet. 3:1993;56-61.
11. Davisson M.et al. Segmental trisomy as a mouse model for Down syndrome. Prog. Clin. Biol. Res. 384:1993;117-133.
12. Reeves R.et al. A mouse model for Down syndrome exhibits learning and behaviour deficits. Nat. Genet. 11:1995;177-184.
13. Sago H.et al. Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities. Proc. Natl. Acad. Sci. U. S. A. 95:1998;6256-6261.
14. Kola I., Hertzog P. Down syndrome and mouse models. Curr. Opin. Genet. Dev. 8:1998;316-321.
15. Fournier R.E.K., Ruddle F.H. Microcell mediated transfer of murine chromosomes into mouse, chinese hamster, and human somatic cells. Proc. Natl. Acad. Sci. U. S. A. 74:1977;319-323.
16. Koi M.et al. Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11. Science. 260:1993;361-364.
17. Hernandez D.et al. Transchromosomal mouse embryonic stem cell lines that contain a freely segregating whole or partial human chromosome 21. Hum. Mol. Genet. 8:1999;923-933.
18. Tomizuka K.et al. Functional expression and germline transmission of a human chromosome fragment in chimeric mice. Nat. Genet. 16:1997;133-143.
19. Itzhaki J.E.et al. Construction by gene targeting in human cells of a `conditional' CDC2 mutant that rereplicates its DNA. Nat. Genet. 15:1997;258-265.
20. Dieken E.S.et al. Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids. Nat. Genet. 12:1996;174-182.
21. Grimes B., Cooke H. Engineering mammalian chromosomes. Hum. Mol. Genet. 7:1998;1635-1640.
22. Kuroiwa Y.et al. Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells. Nucleic Acids Res. 26:1998;3447-3448.
23. Buerstedde J.M., Takeda S. Increased ratio of targeted to random integration after transfection of chicken B cell lines. Cell. 67:1991;179-188.
24. Shen M.H.et al. Human mini-chromosomes in mouse embryonal stem cells. Hum. Mol. Genet. 6:1997;1375-1382.
25. Sauer B. Inducible gene targeting in mice using the Cre/lox system. Methods. 14:1998;381-392.
26. Ramirez-Solis R.et al. Chromosome engineering in mice. Nature. 378:1995;720-724.
27. Liu P.et al. Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics. 150:1998;1155-1168.
28. Smith A.J.H.et al. A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. Nat. Genet. 9:1995;376-384.
29. Van Deursen J.et al. Cre-mediated site-specific translocation between nonhomologous mouse chromosomes. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7376-7380.
30. Herault Y.et al. Engineering chromosomes in mice through targeted meiotic recombination (TAMERE). Nat. Genet. 20:1998;381-384.
31. Tease C., Fisher G. A long-lived trisomy 19 mouse. Mouse News Letter. 72:1985;105.
32. de Boer P. Fertile tertiary trisomy in the mouse (Mus musculus). Cytogenet. Cell Genet. 12:1973;435-442.
33. Smith D.et al. Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2. Genomics. 27:1995;425-434.
34. Dyban A., Baranov V. Cytogenetics of Mammalian Embryonic Development. 1987;Clarendon Press.
35. Gropp A.et al. Murine trisomy: developmental profiles of the embryo, and isolation of trisomic cellular systems. J. Exp. Zool. 228:1983;253-269.
36. Smith B., Walker N. Lens and mesenchyme ultrastructure in gestational day 11 trisomy 1 mice. Teratology. 46:1992;583-598.
37. Cacheiro N.et al. Cytogenetic analysis of malformed mouse fetuses derived from balanced translocation heterozygotes. Cytogenet. Cell Genet. 66:1994;139-148.
38. Ninomiya T.et al. Mouse fetal trisomy 13 and hypotrophy of the spinal cord: effect on calbindin-D28k and calretinin expressed by neurons of the spinal cord and dorsal root ganglia. Neuroscience. 57:1993;1109-1120.
39. Morriss-Kay G., Putz B. Abnormal neural fold development in mouse trisomy 12 and trisomy 14. Brain Res. Bull. 16:1986;825-832.
40. Beechey C., Searle A. Effects of zero to four copies of chromosome 15 on mouse embryonic development. Cytogenet. Cell Genet. 47:1988;66-71.
41. Webb S.et al. Cardiac morphology at late fetal stages in the mouse with trisomy 16: consequences for different formation of the atrioventricular junction when compared to humans with trisomy 21. Cardiovasc. Res. 34:1997;515-524.
42. Haydar T.et al. Consequences of trisomy 16 for mouse brain development: corticogenesis in a model of Down syndrome. J. Neurosci. 16:1996;6175-6182.
43. 2 exposure or glutamate receptor stimulation. Brain Res. 787:1998;292-298.
44. Holtzman D.M.et al. Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proc. Natl. Acad. Sci. U. S. A. 93:1996;13333-13338.
45. Gearhart J.et al. Autosomal aneuploidy in mice: generation and developmental consequences. Brain Res. Bull. 16:1986;789-801.
46. Lorke D. Developmental characteristics of trisomy 19 mice. Acta Anat. 150:1994;159-169.
47. Epstein C.et al. Mouse trisomy 16: An animal model of human trisomy 21 (Down syndrome). Ann. New York Acad. Sci. 450:1985;157-168.
48. Demas G.et al. Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice. Behav. Brain Res. 90:1998;199-201.
49. Dierssen M.et al. Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome. Brain Res. 749:1997;238-244.
50. Sterz H.et al. Defects of skeletal morphology, density, and structure in mouse fetuses with trisomy 16. Teratology. 40:1989;627-639.
51. Ewart J., Auerbach R. Defects in thymocyte differentiation and thymocyte-stromal interactions in the trisomy 16 mouse. Dev. Immunol. 2:1992;215-226.
52. Berger C., Epstein C. Delayed thymocyte maturation in the trisomy 16 mouse fetus. J. Immunol. 143:1989;389-396.
53. Escorihuela R.et al. A behavioral assessment of Ts65Dn mice: a putative Down syndrome model. Neurosci. Lett. 199:1995;143-146.
54. Lane N.et al. A fine structural study of the hippocampus and dorsal root ganglion in mouse trisomy 16, a model of Down's syndrome. Cell Biol. Int. 20:1996;673-680.
55. Shetty H.U.et al. Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome. Biochem. J. 313:1996;31-33.
56. Singer H.et al. Morphologic and neurochemical studies of embryonic brain development in murine trisomy 16. Brain Res. 317:1984;155-166.
57. Coussons-Read M., Crnic L. Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: altered behavior in the elevated plus maze and open field. Behav. Genet. 26:1996;7-13.
58. Megias M.et al. Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice. NeuroReport. 8:1997;3475-3478.
59. Cefalu J.et al. Jejunal function and plasma amino acid concentrations in the segmental trisomic Ts65Dn mouse. Growth Dev. Aging. 62:1998;47-59.
60. Siarey R.et al. Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. Neuropharmacology. 36:1997;1549-1554.