메뉴 건너뛰기




Volumn 7, Issue 1, 2013, Pages

Update on the Kelch-like (KLHL) gene family

Author keywords

BTB domain; Cancer; Evolution; Gene family; Gene nomenclature; Kelch domain; KLHL; Mendelian disease; Ubiquitination

Indexed keywords

CULLIN; E3 LIGASE CULLIN 3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CARRIER PROTEIN; KLHL6 PROTEIN, HUMAN; PROTEIN BINDING;

EID: 84890307627     PISSN: 14739542     EISSN: 14797364     Source Type: Journal    
DOI: 10.1186/1479-7364-7-13     Document Type: Article
Times cited : (196)

References (52)
  • 1
    • 0026655315 scopus 로고
    • A family of DNA virus genes that consists of fused portions of unrelated cellular genes
    • Koonin EV, Senkevich TG, Chernos VI: A family of DNA virus genes that consists of fused portions of unrelated cellular genes. Trends Biochem Sci 1992, 17:213-214.
    • (1992) Trends Biochem Sci , vol.17 , pp. 213-214
    • Koonin, E.V.1    Senkevich, T.G.2    Chernos, V.I.3
  • 2
    • 0028110129 scopus 로고
    • The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila
    • DOI 10.1073/pnas.91.22.10717
    • Zollman S, Godt D, Prive GG, Couderc JL, Laski FA: The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc Natl Acad Sci USA 1994, 91:10717-10721. (Pubitemid 24329070)
    • (1994) Proceedings of the National Academy of Sciences of the United States of America , vol.91 , Issue.22 , pp. 10717-10721
    • Zollman, S.1    Godt, D.2    Prive, G.G.3    Couderc, J.-L.4    Laski, F.A.5
  • 3
    • 84866753205 scopus 로고    scopus 로고
    • The BTB-ZF transcription factors
    • Siggs OM, Beutler B: The BTB-ZF transcription factors. Cell Cycle 2012, 11:3358-3369.
    • (2012) Cell Cycle , vol.11 , pp. 3358-3369
    • Siggs, O.M.1    Beutler, B.2
  • 4
    • 0028040875 scopus 로고
    • The POZ domain: A conserved protein-protein interaction motif
    • Bardwell VJ, Treisman R: The POZ domain: a conserved protein-protein interaction motif. Genes Dev 1994, 8:1664-1677. (Pubitemid 24236245)
    • (1994) Genes and Development , vol.8 , Issue.14 , pp. 1664-1677
    • Bardwell, V.J.1    Treisman, R.2
  • 5
    • 0029099016 scopus 로고
    • The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins
    • Albagli O, Dhordain P, Deweindt C, Lecocq G, Leprince D: The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins. Cell Growth Differ 1995, 6:1193-1198.
    • (1995) Cell Growth Differ , vol.6 , pp. 1193-1198
    • Albagli, O.1    Dhordain, P.2    Deweindt, C.3    Lecocq, G.4    Leprince, D.5
  • 6
    • 33845534761 scopus 로고    scopus 로고
    • Born to bind: The BTB protein-protein interaction domain
    • DOI 10.1002/bies.20500
    • Perez-Torrado R, Yamada D, Defossez PA: Born to bind: the BTB protein-protein interaction domain. Bioessays 2006, 28:1194-1202. (Pubitemid 44925439)
    • (2006) BioEssays , vol.28 , Issue.12 , pp. 1194-1202
    • Perez-Torrado, R.1    Yamada, D.2    Defossez, P.-A.3
  • 8
    • 0034268781 scopus 로고    scopus 로고
    • The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel
    • Minor DL, Lin YF, Mobley BC, Avelar A, Jan YN, Berger JM: The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell 2000, 102:657-670.
    • (2000) Cell , vol.102 , pp. 657-670
    • Minor, D.L.1    Lin, Y.F.2    Mobley, B.C.3    Avelar, A.4    Jan, Y.N.5    Berger, J.M.6
  • 9
    • 0033838360 scopus 로고    scopus 로고
    • In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions
    • DOI 10.1128/MCB.20.17.6550-6567.2000
    • Melnick A, Ahmad KF, Arai S, Polinger A, Ball H, Borden KL, Carlile GW, Prive GG, Licht JD: In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions. Mol Cell Biol 2000, 20:6550-6567. (Pubitemid 30650240)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.17 , pp. 6550-6567
    • Melnick, A.1    Ahmad, F.K.2    Arai, S.3    Polinger, A.4    Ball, H.5    Borden, K.L.6    Carlile, G.W.7    Prive, G.G.8    Licht, J.D.9
  • 10
    • 0242575197 scopus 로고    scopus 로고
    • Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases
    • DOI 10.1038/ncb1056
    • Furukawa M, He YJ, Borchers C, Xiong Y: Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. Nat Cell Biol 2003, 5:1001-1007. (Pubitemid 37406914)
    • (2003) Nature Cell Biology , vol.5 , Issue.11 , pp. 1001-1007
    • Furukawa, M.1    He, Y.J.2    Borchers, C.3    Xiong, Y.4
  • 11
    • 0141493447 scopus 로고    scopus 로고
    • BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3
    • DOI 10.1038/nature01985
    • Xu L, Wei Y, Reboul J, Vaglio P, Shin TH, Vidal M, Elledge SJ, Harper JW: BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. Nature 2003, 425:316-321. (Pubitemid 37158409)
    • (2003) Nature , vol.425 , Issue.6955 , pp. 316-321
    • Xu, L.1    Wei, Y.2    Reboul, J.3    Vaglio, P.4    Shin, T.-H.5    Vidal, M.6    Elledge, S.J.7    Harper, J.W.8
  • 12
    • 0033961690 scopus 로고    scopus 로고
    • The kelch repeat superfamily of proteins: Propellers of cell function
    • DOI 10.1016/S0962-8924(99)01673-6, PII S0962892499016736
    • Adams J, Kelso R, Cooley L: The kelch repeat superfamily of proteins: propellers of cell function. Trends Cell Biol 2000, 10:17-24. (Pubitemid 30017862)
    • (2000) Trends in Cell Biology , vol.10 , Issue.1 , pp. 17-24
    • Adams, J.1    Kelso, R.2    Cooley, L.3
  • 13
    • 8544277232 scopus 로고    scopus 로고
    • The BACK domain in BTB-kelch proteins
    • DOI 10.1016/j.tibs.2004.10.003, PII S0968000404002634
    • Stogios PJ, Prive GG: The BACK domain in BTB-kelch proteins. Trends Biochem Sci 2004, 29:634-637. (Pubitemid 39491260)
    • (2004) Trends in Biochemical Sciences , vol.29 , Issue.12 , pp. 634-637
    • Stogios, P.J.1    Prive, G.G.2
  • 15
    • 4043067989 scopus 로고    scopus 로고
    • Genetic alterations of the NRP/B gene are associated with human brain tumors
    • DOI 10.1038/sj.onc.1207776
    • Liang XQ, Avraham HK, Jiang S, Avraham S: Genetic alterations of the NRP/B gene are associated with human brain tumors. Oncogene 2004, 23:5890-5900. (Pubitemid 39093533)
    • (2004) Oncogene , vol.23 , Issue.35 , pp. 5890-5900
    • Liang, X.-Q.1    Avraham, H.K.2    Jiang, S.3    Avraham, S.4
  • 17
    • 53049105119 scopus 로고    scopus 로고
    • Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer
    • 1368 e1351-1354
    • Shibata T, Kokubu A, Gotoh M, Ojima H, Ohta T, Yamamoto M, Hirohashi S: Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer. Gastroenterology 2008, 135:1358-1368. 1368 e1351-1354.
    • (2008) Gastroenterology , vol.135 , pp. 1358-1368
    • Shibata, T.1    Kokubu, A.2    Gotoh, M.3    Ojima, H.4    Ohta, T.5    Yamamoto, M.6    Hirohashi, S.7
  • 20
    • 84900990099 scopus 로고    scopus 로고
    • MyHits. [http://myhits.isb-sib.ch]
    • MyHits
  • 21
    • 84900991284 scopus 로고    scopus 로고
    • National Center for Biotechnology Information (NCBI). [http://www.ncbi.nlm.nih.gov/protein]
  • 22
    • 84900991287 scopus 로고    scopus 로고
    • European Bioinformatics Institute (EBI). [http:/www.ebi.ac.uk/Tools/msa/ clustalo]
  • 23
    • 84900991288 scopus 로고    scopus 로고
    • Bioinformatics Services. [http://www.ebi.ac.uk/Tools/phylogeny/clustalw2- phylogeny]
    • Bioinformatics Services
  • 25
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M: Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999, 13:76-86. (Pubitemid 29045117)
    • (1999) Genes and Development , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 26
    • 33845682863 scopus 로고    scopus 로고
    • Carcinogenesis and transcriptional regulation through Maf recognition elements
    • DOI 10.1111/j.1349-7006.2006.00358.x
    • Motohashi H, Yamamoto M: Carcinogenesis and transcriptional regulation through Maf recognition elements. Cancer Sci 2007, 98:135-139. (Pubitemid 44941863)
    • (2007) Cancer Science , vol.98 , Issue.2 , pp. 135-139
    • Motohashi, H.1    Yakamoto, M.2
  • 27
    • 0036668466 scopus 로고    scopus 로고
    • Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
    • DOI 10.1046/j.1365-2443.2002.00561.x
    • Kobayashi M, Itoh K, Suzuki T, Osanai H, Nishikawa K, Katoh Y, Takagi Y, Yamamoto M: Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 2002, 7:807-820. (Pubitemid 34947084)
    • (2002) Genes to Cells , vol.7 , Issue.8 , pp. 807-820
    • Kobayashi, M.1    Itoh, K.2    Suzuki, T.3    Osanai, H.4    Nishikawa, K.5    Katoh, Y.6    Takagi, Y.7    Yamamoto, M.8
  • 28
    • 3543008924 scopus 로고    scopus 로고
    • Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
    • DOI 10.1128/MCB.24.16.7130-7139.2004
    • Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, Igarashi K, Yamamoto M: Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 2004, 24:7130-7139. (Pubitemid 39014439)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.16 , pp. 7130-7139
    • Kobayashi, A.1    Kang, M.-I.2    Okawa, H.3    Ohtsuji, M.4    Zenke, Y.5    Chiba, T.6    Igarashi, K.7    Yamamoto, M.8
  • 29
    • 11144264663 scopus 로고    scopus 로고
    • BTB protein keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase
    • DOI 10.1128/MCB.25.1.162-171.2005
    • Furukawa M, Xiong Y: BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Mol Cell Biol 2005, 25:162-171. (Pubitemid 40039808)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.1 , pp. 162-171
    • Furukawa, M.1    Xiong, Y.2
  • 30
    • 0037821802 scopus 로고    scopus 로고
    • Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
    • DOI 10.1074/jbc.M300931200
    • McMahon M, Itoh K, Yamamoto M, Hayes JD: Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J Biol Chem 2003, 278:21592-21600. (Pubitemid 36792558)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.24 , pp. 21592-21600
    • McMahon, M.1    Itoh, K.2    Yamamoto, M.3    Hayes, J.D.4
  • 32
    • 33845981493 scopus 로고    scopus 로고
    • PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex
    • DOI 10.1074/jbc.M606539200
    • Lo SC, Hannink M: PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex. J Biol Chem 2006, 281:37893-37903. (Pubitemid 46042093)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.49 , pp. 37893-37903
    • Lo, S.-C.1    Hannink, M.2
  • 33
    • 84878681301 scopus 로고    scopus 로고
    • The Keap1-Nrf2 system in cancers: Stress response and anabolic metabolism
    • Mitsuishi Y, Motohashi H, Yamamoto M: The Keap1-Nrf2 system in cancers: stress response and anabolic metabolism. Frontiers in oncology 2012, 2:200.
    • (2012) Frontiers in Oncology , vol.2 , pp. 200
    • Mitsuishi, Y.1    Motohashi, H.2    Yamamoto, M.3
  • 38
    • 14844282064 scopus 로고    scopus 로고
    • Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven
    • DOI 10.1111/j.1471-4159.2004.02946.x
    • Jiang S, Avraham HK, Park SY, Kim TA, Bu X, Seng S, Avraham S: Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven. J Neurochem 2005, 92:1191-1203. (Pubitemid 40344309)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.5 , pp. 1191-1203
    • Jiang, S.1    Avraham, H.K.2    Park, S.-Y.3    Kim, T.-A.4    Bu, X.5    Seng, S.6    Avraham, S.7
  • 39
    • 77952625341 scopus 로고    scopus 로고
    • Subcellular localization of Mayven following expression of wild type and mutant EGFP tagged cDNAs
    • Montague P, Kennedy PG, Barnett SC: Subcellular localization of Mayven following expression of wild type and mutant EGFP tagged cDNAs. BMC Neurosci 2010, 11:63.
    • (2010) BMC Neurosci , vol.11 , pp. 63
    • Montague, P.1    Kennedy, P.G.2    Barnett, S.C.3
  • 40
  • 41
    • 79960193538 scopus 로고    scopus 로고
    • Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis
    • Tseng LA, Bixby JL: Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis. Mol Cell Neurosci 2011, 47:254-264.
    • (2011) Mol Cell Neurosci , vol.47 , pp. 254-264
    • Tseng, L.A.1    Bixby, J.L.2
  • 42
    • 77953627257 scopus 로고    scopus 로고
    • Phenotype associated with mutation in the recently identified autosomal dominant retinitis pigmentosa KLHL7 gene
    • Hugosson T, Friedman JS, Ponjavic V, Abrahamson M, Swaroop A, Andréasson S: Phenotype associated with mutation in the recently identified autosomal dominant retinitis pigmentosa KLHL7 gene. Arch Ophthalmol 2010, 128:772-778.
    • (2010) Arch Ophthalmol , vol.128 , pp. 772-778
    • Hugosson, T.1    Friedman, J.S.2    Ponjavic, V.3    Abrahamson, M.4    Swaroop, A.5    Andréasson, S.6
  • 44
    • 80052981806 scopus 로고    scopus 로고
    • Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation
    • Kigoshi Y, Tsuruta F, Chiba T: Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation. J Biol Chem 2011, 286:33613-33621.
    • (2011) J Biol Chem , vol.286 , pp. 33613-33621
    • Kigoshi, Y.1    Tsuruta, F.2    Chiba, T.3
  • 47
    • 84884200851 scopus 로고    scopus 로고
    • Giant axonal neuropathy caused by a novel compound heterozygous mutation in the gigaxonin gene
    • doi:10.1177/0883073812467688
    • Xu M, Da YW, Liu L, Wang F, Jia JP: Giant axonal neuropathy caused by a novel compound heterozygous mutation in the gigaxonin gene. J Child Neurol 2012. doi:10.1177/0883073812467688.
    • (2012) J Child Neurol
    • Xu, M.1    Da, Y.W.2    Liu, L.3    Wang, F.4    Jia, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.