Increased sarcolemmal Na+/H+ exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block

Frontiers in Physiology

Volumn 4 NOV, Issue , 2013, Pages

  van Borren, Marcel M G J ^a   Vos, Marc A ^b   Houtman, Marien J C ^b   Antoons, Gudrun ^b   Ravesloot, Jan H ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

AE; CHE; Compensated cardiac hypertrophy; NBC; NHE 1

Indexed keywords

BICARBONATE SODIUM COTRANSPORTER; CARRIER PROTEINS AND BINDING PROTEINS; CHLORIDE BICARBONATE EXCHANGER; CHLORIDE HYDROXIDE EXCHANGER; PROTON; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR BLOCK; CELL MEMBRANE TRANSPORT; CELL PH; CELLULAR DISTRIBUTION; CHEMICAL PARAMETERS; CHRONIC DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE; MALE; NONHUMAN; NORMALIZED PER LITER CELL WATER; PROTON SODIUM EXCHANGE; SODIUM CELL LEVEL; STEADY STATE; SURFACE TO VOLUME RATIO;

EID: 84890303624     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00322     Document Type: Article

References (53)

1. + exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits. Cardiovasc. Res. 63, 273-282. doi: 10.1016/j.cardiores.2004.04.014
2. Andersen, G. O., Oie, E., Vinge, L. E., Yndestad, A., Attramadal, H., Skomedal, T., et al. (2006). Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts. Basic Res. Cardiol. 101, 471-478. doi: 10.1007/s00395-006-0604-5
3. Antoons, G., Oros, A., Beekman, H., Houtman, M., Engelen, M., Belardinelli, L., et al. (2008). Inhibition of late Na-current by ranolazine reduces Torsade de Pointes arrhythmias in the dog with chronic atrio-ventricular block. Heart Rhythm Abstr. 5, S115.
4. Antoons, G., Oros, A., Bito, V., Sipido, K. R., and Vos, M. A. (2007). Cellular basis for triggered ventricular arrhythmias that occur in the setting of compensated hypertrophy and heart failure: considerations for diagnosis and treatment. J. Electrocardiol. 40, S8-S14. doi: 10.1016/j.jelectrocard.2007.05.022
5. +-exchanger in the heart. Curr. Vasc. Pharmacol. 4, 23-29. doi: 10.2174/157016106775203117
6. Baartscheer, A., and van Borren, M. M. G. J. (2008). Sodium ion transporters as new therapeutic targets in heart failure. Cardiovasc. Hematol. Agents Med. Chem. 6, 229-236. doi: 10.2174/187152508785909546
7. +-exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodeling. Br. J. Pharmacol. 154, 1266-1275. doi: 10.1038/bjp.2008.189
8. +-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure. Cardiovasc. Res. 65, 83-92. doi: 10.1016/j.cardiores.2004.09.024
9. +]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model. Cardiovasc. Res. 57, 1015-1024. doi: 10.1016/S0008-6363(02)00809-X
10. + in normal and failing cardiac myocytes. Ann. N.Y. Acad. Sci. 1080, 165-77. doi: 10.1196/annals.1380.015
11. Bikkina, M., Larson, M. G., and Levy, D. (1993). Asymptomatic ventricular arrhythmias and mortality risk in subjects with left ventricular hypertrophy. J. Am. Coll. Cardiol. 22, 1111-1116. doi: 10.1016/0735-1097(93)90424-Y
12. + exchanger. Cardiovasc. Res. 53, 862-868. doi: 10.1016/S0008-6363(01)00544-2
13. + exchange inhibitor cariporide. J. Pharmacol. Exp. Ther. 298, 469-476.
14. - anion-exchanger in the hypertrophied myocardium. Cardiovasc. Res. 51, 71-79. doi: 10.1016/S0008-6363(01)00276-0
15. Cingolani, H. E., Perez, N. G., Aiello, E. A., Ennis, I. L., Garciarena, C. D., Villa-Abrille, M. C., et al. (2008). Early signals after stretch leading to cardiac hypertrophy. Key role of NHE-1. Front. Biosci. 13, 7096-7114. doi: 10.2741/3213
16. + exchange inhibition. Hypertension 41, 373-377. doi: 10.1161/01.HYP.0000051502.93374.1C
17. + exchanger in the mammalian myocardium. Mol. Cell. Biochem. 302, 145-155. doi: 10.1007/s11010-007-9436-3
18. + exchanger contributes to left ventricular hypertrophy in the Goto-Kakizaki rat model of type 2 diabetes: critical role of Akt. Diabetologia 50, 1335-1344. doi: 10.1007/s00125-007-0628-x
19. - symport in the sheep cardiac Purkinje fibre. J. Physiol. 451, 365-385.
20. Di Diego, J. M., Cordeiro, J. M., Goodrow, R. J., Fish, J. M., Zygmunt, A. C., Perez, G. J., et al. (2002). Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males. Circulation 106, 2004-2011. doi: 10.1161/01.CIR.0000032002.22105.7A
21. + exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice. Circ. Res. 90, 814-819. doi: 10.1161/01.RES.0000014966.97486.C0
22. + exchanger-1 (NHE-1) inhibition. Can. J. Physiol. Pharmacol. 85, 301-310. doi: 10.1139/y06-072
23. Gerdes, A. M. (2002). Cardiac myocyte remodeling in hypertrophy and progression to failure. J. Card. Fail. 8, S264-S268. doi: 10.1054/jcaf.2002.129280
24. Gray, R. P., McIntyre, H., Sheridan, D. S., and Fry, C. H. (2001). Intracellular sodium and contractile function in hypertrophied human and guinea-pig myocardium. Pflügers Arch. 442, 117-123. doi: 10.1007/s004240000512
25. + exchange inhibition-induced cardioprotection in dogs: effects on neutrophils versus cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol. 279, H1563-H1570.
26. Gumina, R. J., El Schultz, J., Moore, J., Beier, N., Schelling, P., and Gross, G. J. (2005). Cardioprotective-mimetics reduce myocardial infarct size in animals resistant to ischemic preconditioning. Cardiovasc. Drugs Ther. 19, 315-322. doi: 10.1007/s10557-005-3693-8
27. + exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice. Circulation 112, 2307-2317. doi: 10.1161/CIRCULATIONAHA.105.542209
28. Kondo, R. P., Dederko, D. A., Teutsch, C., Chrast, J., Catalucci, D., Chien, K. R., et al. (2006). Comparison of contraction and calcium handling between right and left ventricular myocytes from adult mouse heart: a role for repolarization waveform. J. Physiol. 571, 131-146. doi: 10.1113/jphysiol.2005.101428
29. + exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats. Am. J. Physiol. Heart Circ. Physiol. 280, H738-H745.
30. Lagadic-Gossmann, D., Buckler, K. J., and Vaughan-Jones, R. D. (1992). Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte. J. Physiol. 458, 361-384.
31. 3-dependent alkalinizing transporter in adult rat ventricular myocytes: characterization and modulation. Am. J. Physiol. 273, H2596-H2603.
32. Leem, C. H., Lagadic-Gossmann, D., and Vaughan-Jones, R. D. (1999). Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte. J. Physiol. 517(Pt 1), 159-180. doi: 10.1111/j.1469-7793.1999.0159z.x
33. Leem, C. H., and Vaughan-Jones, R. D. (1998). Out-of-equilibrium pH transients in the guinea-pig ventricular myocyte. J. Physiol. 509(Pt 2), 471-485. doi: 10.1111/j.1469-7793.1998.471bn.x
34. 2+ signals that induce cardiac hypertrophy and heart failure. Circ. Res. 103, 891-899. doi: 10.1161/CIRCRESAHA.108.175141
35. + exchanger-1 inhibitor, on ischemia and reperfusion-induced myocardial infarction in rats and dogs. Fundam. Clin. Pharmacol. 21, 255-263. doi: 10.1111/j.1472-8206.2007.00491.x
36. Oikarinen, L., Nieminen, M. S., Viitasalo, M., Toivonen, L., Wachtell, K., Papademetriou, V., et al. (2001). Relation of QT interval and QT dispersion to echocardiographic left ventricular hypertrophy and geometric pattern in hypertensive patients. The LIFE study. The Losartan Intervention For Endpoint Reduction. J. Hypertens. 19, 1883-1891. doi: 10.1097/00004872-200110000-00025
37. Pogwizd, S. M., Sipido, K. R., Verdonck, F., and Bers, D. M. (2003). Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis. Cardiovasc. Res. 57, 887-896. doi: 10.1016/S0008-6363(02)00735-6
38. 3 symporter in the rat heart after myocardial infarction. J. Am. Coll. Cardiol. 37, 2154-2165. doi: 10.1016/S0735-1097(01)01287-6
39. Satoh, H., Delbridge, L. M., Blatter, L. A., and Bers, D. M. (1996). Surface:volume relationship in cardiac myocytes studied with confocal microscopy and membrane capacitance measurements: species-dependence and developmental effects. Biophys. J. 70, 1494-1504. doi: 10.1016/S0006-3495(96)79711-4
40. Schoenmakers, M., Ramakers, C., van Opstal, J. M., Leunissen, J. D., Londono, C., and Vos, M. A. (2003). Asynchronous development of electrical remodeling and cardiac hypertrophy in the complete AV block dog. Cardiovasc. Res. 59, 351-359. doi: 10.1016/S0008-6363(03)00430-9
41. 2+ release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractile adaptation and arrhythmogenesis. Circulation 102, 2137-2144. doi: 10.1161/01.CIR.102.17.2137
42. Thomsen, M. B., Verduyn, S. C., Stengl, M., Beekman, J. D., de Pater, G., van Opstal, J., et al. (2004). Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs. Circulation 110, 2453-2459. doi: 10.1161/01.CIR.0000145162.64183.C8
43. Tomaselli, G. F., and Marban, E. (1999). Electrophysiological remodeling in hypertrophy and heart failure. Cardiovasc. Res. 42, 270-283. doi: 10.1016/S0008-6363(99)00017-6
44. van Borren, M. M. G. J., Baartscheer, A., Wilders, R., and Ravesloot, J. H. (2004). NHE-1 and NBC during pseudo-ischemia/reperfusion in rabbit ventricular myocytes. J. Mol. Cell. Cardiol. 37, 567-577. doi: 10.1016/j.yjmcc.2004.05.017
45. van Borren, M. M. G. J., Zegers, J., Baartscheer, A., and Ravesloot, J. H. (2006). Contribution of NHE-1 to cell length shortening of normal and failing rabbit cardiac myocytes. J. Mol. Cell. Cardiol. 41, 706-715. doi: 10.1016/j.yjmcc.2006.07.001
46. van Opstal, J. M., Verduyn, S. C., Leunissen, H. D., de Groot, S. H., Wellens, H. J., and Vos, M. A. (2001). Electrophysiological parameters indicative of sudden cardiac death in the dog with chronic complete AV-block. Cardiovasc. Res. 50, 354-361. doi: 10.1016/S0008-6363(01)00226-7
47. + concentration and altered Na/K pump activity in hypertrophied canine ventricular cells. Cardiovasc. Res. 57, 1035-1043. doi: 10.1016/S0008-6363(02)00734-4
48. Verduyn, S. C., Vos, M. A., van der Zande, J., Kulcsar, A., and Wellens, H. J. (1997). Further observations to elucidate the role of interventricular dispersion of repolarization and early afterdepolarizations in the genesis of acquired torsade de pointes arrhythmias: a comparison between almokalant and d-sotalol using the dog as its own control. J. Am. Coll. Cardiol. 30, 1575-1584. doi: 10.1016/S0735-1097(97)00333-1
49. Volders, P. G., Sipido, K. R., Carmeliet, E., Spatjens, R. L., Wellens, H. J., and Vos, M. A. (1999). Repolarizing K+ currents ITO1 and IKs are larger in right than left canine ventricular midmyocardium. Circulation 99, 206-210. doi: 10.1161/01.CIR.99.2.206
50. Vos, M. A., de Groot, S. H., Verduyn, S. C., van der Zande, J., Leunissen, H. D., Cleutjens, J. P., et al. (1998). Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling. Circulation 98, 1125-1135. doi: 10.1161/01.CIR.98.11.1125
51. 3 cotransport in pressure overload hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 293, H1254-H1264. doi: 10.1152/ajpheart.00964.2006
52. 3 cotransport in ventricular myocytes from rat, rabbit and guinea pig. J. Physiol. 562, 455-475. doi: 10.1113/jphysiol.2004.071068
53. + exchanger activity and expression in human ventricular myocardium. J. Am. Coll. Cardiol. 36, 534-540. doi: 10.1016/S0735-1097(00)00730-0