-
1
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
PMID:21376230
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID:21376230; http://dx.doi.org/10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0034663989
-
HIF-1 and human disease: One highly involved factor
-
PMID:10950862
-
Semenza GL. HIF-1 and human disease: one highly involved factor. Genes Dev 2000; 14:1983-91; PMID:10950862
-
(2000)
Genes Dev
, vol.14
, pp. 1983-1991
-
-
Semenza, G.L.1
-
3
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
PMID:17925579
-
Semenza GL. Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007; 2007:cm8; PMID:17925579; http://dx.doi.org/10.1126/stke.4072007cm8
-
(2007)
Sci STKE
, vol.2007
-
-
Semenza, G.L.1
-
4
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
PMID:11902584
-
Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2002; 2:38-47; PMID:11902584; http://dx.doi.org/10.1038/nrc704
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
5
-
-
56149089262
-
Hypoxia-inducible factor 1 and cancer pathogenesis
-
PMID:18506846
-
Semenza GL. Hypoxia-inducible factor 1 and cancer pathogenesis. IUBMB Life 2008; 60:591-7; PMID:18506846; http://dx.doi.org/10.1002/iub.93
-
(2008)
IUBMB Life
, vol.60
, pp. 591-597
-
-
Semenza, G.L.1
-
6
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
PMID:7539918
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 1995; 92:5510-4; PMID:7539918; http://dx.doi.org/10.1073/ pnas.92.12.5510
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
7
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
(Bethesda) PMID:15304631
-
Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology (Bethesda) 2004; 19:176-82; PMID:15304631; http://dx.doi.org/10.1152/physiol.00001.2004
-
(2004)
Physiology
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
8
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
PMID:11598268
-
Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001; 294:1337-40; PMID:11598268; http://dx.doi.org/10.1126/ science.1066373
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
9
-
-
0035917313
-
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
-
PMID:11292862
-
Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG Jr. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001; 292:464-8; PMID:11292862; http://dx.doi.org/10.1126/science.1059817
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
10
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
PMID:10353251
-
Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999; 399:271-5; PMID:10353251; http://dx.doi.org/10.1038/20459
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
11
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
PMID:16234508
-
Wenger RH, Stiehl DP, Camenisch G. Integration of oxygen signaling at the consensus HRE. Sci STKE 2005; 2005:re12; PMID:16234508
-
(2005)
Sci STKE
, vol.2005
-
-
Wenger, R.H.1
Stiehl, D.P.2
Camenisch, G.3
-
12
-
-
40949142209
-
The role of hypoxia-inducible factors in tumorigenesis
-
PMID:18259193
-
Rankin EB, Giaccia AJ. The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 2008; 15:678-85; PMID:18259193; http://dx.doi.org/10.1038/cdd.2008.21
-
(2008)
Cell Death Differ
, vol.15
, pp. 678-685
-
-
Rankin, E.B.1
Giaccia, A.J.2
-
13
-
-
77952773418
-
VHL and HIF signalling in renal cell carcinogenesis
-
PMID:20225241
-
Baldewijns MM, van Vlodrop IJ, Vermeulen PB, Soetekouw PM, van Engeland M, de Bruïne AP. VHL and HIF signalling in renal cell carcinogenesis. J Pathol 2010; 221:125-38; PMID:20225241; http://dx.doi.org/10.1002/path.2689
-
(2010)
J Pathol
, vol.221
, pp. 125-138
-
-
Baldewijns, M.M.1
Van Vlodrop, I.J.2
Vermeulen, P.B.3
Soetekouw, P.M.4
Van Engeland, M.5
De Bruïne, A.P.6
-
14
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
PMID:10749120
-
Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 2000; 60:1541-5; PMID:10749120
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
-
15
-
-
0032725554
-
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
-
PMID:10551817
-
Richard DE, Berra E, Gothié E, Roux D, Pouysségur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. J Biol Chem 1999; 274:32631-7; PMID:10551817; http://dx.doi.org/10.1074/jbc.274.46. 32631
-
(1999)
J Biol Chem
, vol.274
, pp. 32631-32637
-
-
Richard, D.E.1
Berra, E.2
Gothié, E.3
Roux, D.4
Pouysségur, J.5
-
16
-
-
33845403070
-
Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha
-
PMID:16954218
-
Mylonis I, Chachami G, Samiotaki M, Panayotou G, Paraskeva E, Kalousi A, Georgatsou E, Bonanou S, Simos G. Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. J Biol Chem 2006; 281:33095-106; PMID:16954218; http://dx.doi.org/10.1074/jbc.M605058200
-
(2006)
J Biol Chem
, vol.281
, pp. 33095-33106
-
-
Mylonis, I.1
Chachami, G.2
Samiotaki, M.3
Panayotou, G.4
Paraskeva, E.5
Kalousi, A.6
Georgatsou, E.7
Bonanou, S.8
Simos, G.9
-
17
-
-
34247583794
-
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner
-
PMID:17325032
-
Flügel D, Görlach A, Michiels C, Kietzmann T. Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner. Mol Cell Biol 2007; 27:3253-65; PMID:17325032; http://dx.doi.org/10.1128/MCB.00015-07
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3253-3265
-
-
Flügel, D.1
Görlach, A.2
Michiels, C.3
Kietzmann, T.4
-
18
-
-
0037119415
-
Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway
-
PMID:12052835
-
Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, Neckers LM. Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway. J Biol Chem 2002; 277:29936-44; PMID:12052835; http://dx.doi.org/10.1074/jbc.M204733200
-
(2002)
J Biol Chem
, vol.277
, pp. 29936-29944
-
-
Isaacs, J.S.1
Jung, Y.J.2
Mimnaugh, E.G.3
Martinez, A.4
Cuttitta, F.5
Neckers, L.M.6
-
19
-
-
78649814934
-
Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha
-
PMID:20889502
-
Xu D, Yao Y, Lu L, Costa M, Dai W. Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha. J Biol Chem 2010; 285:38944-50; PMID:20889502; http://dx.doi.org/10. 1074/jbc.M110.160325
-
(2010)
J Biol Chem
, vol.285
, pp. 38944-38950
-
-
Xu, D.1
Yao, Y.2
Lu, L.3
Costa, M.4
Dai, W.5
-
20
-
-
0036528246
-
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
-
PMID:12086860
-
Kondo K, Klco J, Nakamura E, Lechpammer M, Kaelin WG Jr. Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 2002; 1:237-46; PMID:12086860; http://dx.doi.org/10.1016/S1535-6108(02) 00043-0
-
(2002)
Cancer Cell
, vol.1
, pp. 237-246
-
-
Kondo, K.1
Klco, J.2
Nakamura, E.3
Lechpammer, M.4
Kaelin Jr., W.G.5
-
21
-
-
0027742184
-
Distinct roles for cyclin-dependent kinases in cell cycle control
-
PMID:8266103
-
van den Heuvel S, Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 1993; 262:2050-4; PMID:8266103; http://dx.doi.org/10.1126/science.8266103
-
(1993)
Science
, vol.262
, pp. 2050-2054
-
-
Van Den Heuvel, S.1
Harlow, E.2
-
22
-
-
0033166064
-
Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
-
PMID:10395539
-
Hagting A, Jackman M, Simpson K, Pines J. Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal. Curr Biol 1999; 9:680-9; PMID:10395539; http://dx.doi.org/10.1016/S0960- 9822(99)80308-X
-
(1999)
Curr Biol
, vol.9
, pp. 680-689
-
-
Hagting, A.1
Jackman, M.2
Simpson, K.3
Pines, J.4
-
23
-
-
36349030360
-
Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase
-
PMID:17893151
-
Chen D, Gould C, Garza R, Gao T, Hampton RY, Newton AC. Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase. J Biol Chem 2007; 282:33776-87; PMID:17893151; http://dx.doi.org/10.1074/jbc.M703320200
-
(2007)
J Biol Chem
, vol.282
, pp. 33776-33787
-
-
Chen, D.1
Gould, C.2
Garza, R.3
Gao, T.4
Hampton, R.Y.5
Newton, A.C.6
-
24
-
-
0345491599
-
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
-
PMID:14645546
-
Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol 2003; 23:9361-74; PMID:14645546; http://dx.doi.org/10. 1128/MCB.23.24.9361-9374.2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9361-9374
-
-
Hu, C.J.1
Wang, L.Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
25
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
PMID:16517406
-
Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006; 3:187-97; PMID:16517406; http://dx.doi.org/10. 1016/j.cmet.2006.01.012
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
26
-
-
80755125565
-
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity
-
PMID:22037377
-
Anastassiadis T, Deacon SW, Devarajan K, Ma H, Peterson JR. Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nat Biotechnol 2011; 29:1039-45; PMID:22037377; http://dx.doi.org/10.1038/nbt.2017
-
(2011)
Nat Biotechnol
, vol.29
, pp. 1039-1045
-
-
Anastassiadis, T.1
Deacon, S.W.2
Devarajan, K.3
Ma, H.4
Peterson, J.R.5
-
27
-
-
84860406130
-
Spectral imaging-based methods for quantifying autophagy and apoptosis
-
PMID:21757995
-
Dolloff NG, Ma X, Dicker DT, Humphreys RC, Li LZ, El-Deiry WS. Spectral imaging-based methods for quantifying autophagy and apoptosis. Cancer Biol Ther 2011; 12:349-56; PMID:21757995; http://dx.doi.org/10.4161/cbt.12.4.17175
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 349-356
-
-
Dolloff, N.G.1
Ma, X.2
Dicker, D.T.3
Humphreys, R.C.4
Li, L.Z.5
El-Deiry, W.S.6
-
28
-
-
79960958978
-
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1
-
PMID:21646472
-
Mayes PA, Dolloff NG, Daniel CJ, Liu JJ, Hart LS, Kuribayashi K, Allen JE, Jee DI, Dorsey JF, Liu YY, et al. Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1. Cancer Res 2011; 71:5265-75; PMID:21646472; http://dx.doi.org/10.1158/0008-5472.CAN-11-1383
-
(2011)
Cancer Res
, vol.71
, pp. 5265-5275
-
-
Mayes, P.A.1
Dolloff, N.G.2
Daniel, C.J.3
Liu, J.J.4
Hart, L.S.5
Kuribayashi, K.6
Allen, J.E.7
Jee, D.I.8
Dorsey, J.F.9
Liu, Y.Y.10
-
29
-
-
33746094659
-
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
-
PMID:16818887
-
Vassilev LT, Tovar C, Chen S, Knezevic D, Zhao X, Sun H, Heimbrook DC, Chen L. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci U S A 2006; 103:10660-5; PMID:16818887; http://dx.doi.org/10.1073/pnas.0600447103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10660-10665
-
-
Vassilev, L.T.1
Tovar, C.2
Chen, S.3
Knezevic, D.4
Zhao, X.5
Sun, H.6
Heimbrook, D.C.7
Chen, L.8
-
30
-
-
9444228344
-
Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts
-
PMID:15542782
-
Fry DW, Harvey PJ, Keller PR, Elliott WL, Meade M, Trachet E, Albassam M, Zheng X, Leopold WR, Pryer NK, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther 2004; 3:1427-38; PMID:15542782
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1427-1438
-
-
Fry, D.W.1
Harvey, P.J.2
Keller, P.R.3
Elliott, W.L.4
Meade, M.5
Trachet, E.6
Albassam, M.7
Zheng, X.8
Leopold, W.R.9
Pryer, N.K.10
-
31
-
-
33645802169
-
Cyclin-dependent kinase pathways as targets for cancer treatment
-
PMID:16603719
-
Shapiro GI. Cyclin-dependent kinase pathways as targets for cancer treatment. J Clin Oncol 2006; 24:1770-83; PMID:16603719; http://dx.doi.org/10. 1200/JCO.2005.03.7689
-
(2006)
J Clin Oncol
, vol.24
, pp. 1770-1783
-
-
Shapiro, G.I.1
-
32
-
-
0033954247
-
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
-
PMID:10640274
-
Ravi R, Mookerjee B, Bhujwalla ZM, Sutter CH, Artemov D, Zeng Q, Dillehay LE, Madan A, Semenza GL, Bedi A. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev 2000; 14:34-44; PMID:10640274
-
(2000)
Genes Dev
, vol.14
, pp. 34-44
-
-
Ravi, R.1
Mookerjee, B.2
Bhujwalla, Z.M.3
Sutter, C.H.4
Artemov, D.5
Zeng, Q.6
Dillehay, L.E.7
Madan, A.8
Semenza, G.L.9
Bedi, A.10
-
33
-
-
84857047339
-
PhosphoSitePlus: A comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
-
PMID:22135298
-
Hornbeck PV, Kornhauser JM, Tkachev S, Zhang B, Skrzypek E, Murray B, Latham V, Sullivan M. PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res 2012; 40(Database issue):D261-70; PMID:22135298; http://dx.doi.org/10.1093/nar/gkr1122
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.DATABASE ISSUE
-
-
Hornbeck, P.V.1
Kornhauser, J.M.2
Tkachev, S.3
Zhang, B.4
Skrzypek, E.5
Murray, B.6
Latham, V.7
Sullivan, M.8
-
34
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
-
PMID:12615733
-
Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi P, et al. Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res 2003; 63:1138-43; PMID:12615733
-
(2003)
Cancer Res
, vol.63
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
Iyer, N.7
LaRusch, J.8
Pak, B.9
Taghavi, P.10
-
35
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
-
PMID:10934146
-
Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 2000; 157:411-21; PMID:10934146; http://dx.doi.org/10. 1016/S0002-9440(10)64554-3
-
(2000)
Am J Pathol
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
Harris, A.L.7
-
36
-
-
34047156190
-
HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
-
PMID:17418410
-
Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell 2007; 11:335-47; PMID:17418410; http://dx.doi.org/10.1016/j.ccr.2007.02.006
-
(2007)
Cancer Cell
, vol.11
, pp. 335-347
-
-
Gordan, J.D.1
Bertout, J.A.2
Hu, C.J.3
Diehl, J.A.4
Simon, M.C.5
-
37
-
-
0037214282
-
Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia
-
PMID:12482987
-
Goda N, Ryan HE, Khadivi B, McNulty W, Rickert RC, Johnson RS. Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol Cell Biol 2003; 23:359-69; PMID:12482987; http://dx.doi.org/10. 1128/MCB.23.1.359-369.2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 359-369
-
-
Goda, N.1
Ryan, H.E.2
Khadivi, B.3
McNulty, W.4
Rickert, R.C.5
Johnson, R.S.6
-
38
-
-
16644373473
-
Role of VHL gene mutation in human cancer
-
PMID:15611513
-
Kim WY, Kaelin WG. Role of VHL gene mutation in human cancer. J Clin Oncol 2004; 22:4991-5004; PMID:15611513; http://dx.doi.org/10.1200/JCO.2004.05. 061
-
(2004)
J Clin Oncol
, vol.22
, pp. 4991-5004
-
-
Kim, W.Y.1
Kaelin, W.G.2
-
39
-
-
1342267616
-
The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer
-
PMID:14760118
-
Yoshida T, Tanaka S, Mogi A, Shitara Y, Kuwano H. The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer. Ann Oncol 2004; 15:252-6; PMID:14760118; http://dx.doi.org/10.1093/annonc/mdh073
-
(2004)
Ann Oncol
, vol.15
, pp. 252-256
-
-
Yoshida, T.1
Tanaka, S.2
Mogi, A.3
Shitara, Y.4
Kuwano, H.5
-
40
-
-
0036300779
-
Significance of cyclin B1 expression as an independent prognostic indicator of patients with squamous cell carcinoma of the esophagus
-
PMID:11895914
-
Nozoe T, Korenaga D, Kabashima A, Ohga T, Saeki H, Sugimachi K. Significance of cyclin B1 expression as an independent prognostic indicator of patients with squamous cell carcinoma of the esophagus. Clin Cancer Res 2002; 8:817-22; PMID:11895914
-
(2002)
Clin Cancer Res
, vol.8
, pp. 817-822
-
-
Nozoe, T.1
Korenaga, D.2
Kabashima, A.3
Ohga, T.4
Saeki, H.5
Sugimachi, K.6
-
41
-
-
0031046787
-
WAF1 expression and p53 mutations in human colorectal cancers
-
PMID:9030251
-
Wang A, Yoshimi N, Ino N, Tanaka T, Mori H. WAF1 expression and p53 mutations in human colorectal cancers. J Cancer Res Clin Oncol 1997; 123:118-23; PMID:9030251; http://dx.doi.org/10.1007/BF01269890
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, pp. 118-123
-
-
Wang, A.1
Yoshimi, N.2
Ino, N.3
Tanaka, T.4
Mori, H.5
-
42
-
-
63949088181
-
High cyclin B1 expression is associated with poor survival in breast cancer
-
PMID:19293801
-
Aaltonen K, Amini RM, Heikkilä P, Aittomäki K, Tamminen A, Nevanlinna H, Blomqvist C. High cyclin B1 expression is associated with poor survival in breast cancer. Br J Cancer 2009; 100:1055-60; PMID:19293801; http://dx.doi.org/10.1038/sj.bjc.6604874
-
(2009)
Br J Cancer
, vol.100
, pp. 1055-1060
-
-
Aaltonen, K.1
Amini, R.M.2
Heikkilä, P.3
Aittomäki, K.4
Tamminen, A.5
Nevanlinna, H.6
Blomqvist, C.7
-
43
-
-
77952751368
-
Cdc25 phosphatases are required for timely assembly of CDK1-cyclin B at the G2/M transition
-
PMID:20360007
-
Timofeev O, Cizmecioglu O, Settele F, Kempf T, Hoffmann I. Cdc25 phosphatases are required for timely assembly of CDK1-cyclin B at the G2/M transition. J Biol Chem 2010; 285:16978-90; PMID:20360007; http://dx.doi.org/10. 1074/jbc.M109.096552
-
(2010)
J Biol Chem
, vol.285
, pp. 16978-16990
-
-
Timofeev, O.1
Cizmecioglu, O.2
Settele, F.3
Kempf, T.4
Hoffmann, I.5
-
44
-
-
34250865564
-
CDC25 phosphatases in cancer cells: Key players? Good targets?
-
PMID:17568790
-
Boutros R, Lobjois V, Ducommun B. CDC25 phosphatases in cancer cells: key players? Good targets? Nat Rev Cancer 2007; 7:495-507; PMID:17568790; http://dx.doi.org/10.1038/nrc2169
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 495-507
-
-
Boutros, R.1
Lobjois, V.2
Ducommun, B.3
-
45
-
-
23644453277
-
Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity
-
PMID:16098463
-
Moeller BJ, Dreher MR, Rabbani ZN, Schroeder T, Cao Y, Li CY, Dewhirst MW. Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity. Cancer Cell 2005; 8:99-110; PMID:16098463; http://dx.doi.org/10.1016/j.ccr.2005.06.016
-
(2005)
Cancer Cell
, vol.8
, pp. 99-110
-
-
Moeller, B.J.1
Dreher, M.R.2
Rabbani, Z.N.3
Schroeder, T.4
Cao, Y.5
Li, C.Y.6
Dewhirst, M.W.7
-
46
-
-
34447117505
-
Review: Implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions
-
PMID:17602059
-
Wouters A, Pauwels B, Lardon F, Vermorken JB. Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions. Oncologist 2007; 12:690-712; PMID:17602059; http://dx.doi.org/10. 1634/theoncologist.12-6-690
-
(2007)
Oncologist
, vol.12
, pp. 690-712
-
-
Wouters, A.1
Pauwels, B.2
Lardon, F.3
Vermorken, J.B.4
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