Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants

BMC Genomics

Volumn 9, Issue , 2008, Pages

  Huang, Lingkang ^a,b,c   Heinloth, Alexandra N ^a   Zeng, Zhao Bang ^b   Paules, Richard S ^a   Bushel, Pierre R ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DICHLOROBENZENE; 1,4 DICHLOROBENZENE; ALLYL ALCOHOL; AMINO ACID TRANSPORTER; BROMOBENZENE; CARBON TETRACHLORIDE; CHEMOKINE; DIQUAT; GALACTOSAMINE; GALAPTIN; HERMES ANTIGEN; LIPOCORTIN; LIPOCORTIN 2; MEMBRANE PROTEIN; MONOCROTALINE; NITROSOMORPHOLINE; PARACETAMOL; PHOSPHOPROTEIN; PROTEIN BCL 2; PROTEIN C JUN; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SEMAPHORIN; THIOACETAMIDE; TUMOR NECROSIS FACTOR ALPHA; POISON;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; CYTOTOXICITY; DATA ANALYSIS; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE INTERACTION; GENETIC ANALYSIS; GENETIC SELECTION; HYPOTHESIS; LIVER NECROSIS; LIVER PARENCHYMA; LIVER TOXICITY; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHENOTYPE; PREDICTION; RAT; TOXICOGENETICS; TRANSCRIPTION REGULATION; ANIMAL; BAYES THEOREM; BIOLOGICAL MODEL; CELL DEATH; CHEMICALLY INDUCED DISORDER; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETICS; INFLAMMATION; LIVER; METABOLISM; NECROSIS; PATHOLOGY; PREDICTION AND FORECASTING; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY;

RATTUS;

ANIMALS; APOPTOSIS; BAYES THEOREM; CELL DEATH; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; INFLAMMATION; LIVER; MODELS, BIOLOGICAL; NECROSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POISONS; PREDICTIVE VALUE OF TESTS; PRINCIPAL COMPONENT ANALYSIS; RATS; REPRODUCIBILITY OF RESULTS;

EID: 47949114934     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-9-288     Document Type: Article

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