Is pomegranate juice a potential perpetrator of clinical drug-drug interactions? Review of the in vitro, preclinical and clinical evidence

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 38, Issue 4, 2013, Pages 223-229

  Srinivas, Nuggehally R ^a  

^a Suramus Biopharm   (India)

Author keywords

Clinical; Cytochrome P450; Drug drug interaction; Pharmacokinetics; Pomegranate juice

Indexed keywords

BUSPIRONE; CARBAMAZEPINE; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DICLOFENAC; FLUCONAZOLE; FLURBIPROFEN; MIDAZOLAM; NITRENDIPINE; POMEGRANATE EXTRACT; SULFOTRANSFERASE 1A1; TOLBUTAMIDE; TRIAZOLAM;

AREA UNDER THE CURVE; DISTRIBUTION VOLUME; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISPOSITION; DRUG ELIMINATION; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG PENETRATION; DRUG POTENTIATION; FOOD DRUG INTERACTION; GRAPEFRUIT JUICE; HUMAN; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; POMEGRANATE JUICE; REVIEW;

ANIMALS; ANTI-ANXIETY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARYL HYDROCARBON HYDROXYLASES; BEVERAGES; BUSPIRONE; CACO-2 CELLS; CALCIUM CHANNEL BLOCKERS; CARBAMAZEPINE; CYTOCHROME P-450 CYP3A; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; FLURBIPROFEN; FOOD-DRUG INTERACTIONS; HUMANS; HYPNOTICS AND SEDATIVES; HYPOGLYCEMIC AGENTS; MIDAZOLAM; NITRENDIPINE; PUNICACEAE; TOLBUTAMIDE; TRIAZOLAM;

EID: 84890234379     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-013-0137-x     Document Type: Review

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