Pomegranate juice inhibits sulfoconjugation in caco-2 human colon carcinoma cells

Journal of Medicinal Food

Volumn 11, Issue 4, 2008, Pages 623-628

  Saruwatari, Ayako ^a   Okamura, Shigeaki ^a   Nakajima, Yoko ^a   Narukawa, Yuji ^a   Takeda, Tadahiro ^a   Tamura, Hiroomi ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Caco 2; Pomegranate; Sulfoconjugation

Indexed keywords

1 NAPHTHOL; ANTIOXIDANT; ARYL SULFOTRANSFERASE; BREAST CANCER RESISTANCE PROTEIN; POMEGRANATE EXTRACT; PUNICALAGIN; SULFOTRANSFERASE 1A1; UNCLASSIFIED DRUG;

APPLE JUICE; ARTICLE; CARCINOMA CELL; COLON CARCINOMA; CONCENTRATION RESPONSE; CONJUGATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG GLUCURONIDATION; DRUG ISOLATION; DRUG POTENCY; DRUG PURIFICATION; ENZYME INHIBITION; FRUIT JUICE; GRAPEFRUIT JUICE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INTESTINE EPITHELIUM; INTESTINE FUNCTION; ORANGE JUICE; PEACH; PINEAPPLE JUICE; POMEGRANATE JUICE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIOXIDANTS; ATP-BINDING CASSETTE TRANSPORTERS; BEVERAGES; CACO-2 CELLS; COLONIC NEOPLASMS; FOOD-DRUG INTERACTIONS; GENE EXPRESSION REGULATION; HUMANS; HYDROLYZABLE TANNINS; INTESTINAL MUCOSA; METABOLIC DETOXICATION, PHASE I; NAPHTHOLS; NEOPLASM PROTEINS; PLANT PREPARATIONS; PUNICACEAE; SULFOTRANSFERASES;

ANANAS COMOSUS; CITRUS X PARADISI; LYTHRACEAE; MALUS X DOMESTICA; PRUNUS PERSICA;

EID: 57349144983     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2007.0050     Document Type: Article

References (24)

1. Langley P: Why a pomegranate? BMJ 2005;321:1153-1154.
2. Malik A, Afaq F, Sarfaeaz S, Adhami VM, Syed DN, Mukhtar H: Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer. Proc Natl Acad Sci U S A 2005;102:14813-14818.
3. De Nigris F, Williams-Ignarro S, Lerman LO, Crimi E, Botti C, Mansueto G, D'Armiento FP, De Rosa G, Sica V, Ignarro LJ, Napoli C: Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthetase activity at sites of perturbed shear stress. Proc Natl Acad Sci U S A 2005;102:4896-4901.
4. Hidaka M, Fujita K, Ogikubo T, Yamasaki K, Iwakiri T, Okumura M, Kodama H, Arimori K: Potent inhibition by star fruit of human cytochrome P450 3A (CYP3A) activity. Drug Metab Dispos 2004;32:581-583.
5. Hidaka M, Okumura M, Fujita K, Ogikubo T, Yamasaki K, Iwakiri T, Setoguchi N, Arimori K: Effects of pomegranate juice on human cytochrome P450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug Metab Dispos 2005;33:644-648.
6. Isozaki T, Tamura H: Epigallocatechin gallate (EGCG) inhibits the sulfation of 1-naphthol in a human colon carcinoma cell line, Caco-2. Biol Pharm Bull 2001;24:1076-1078.
7. Okamura S, Tamura H: Effect of herbal teas on conjugation reactions in a human colon carcinoma cell line, Caco-2. J Health Sci 2004;50:189-192.
8. Okamura S, Suzuki K, Yanase M, Koizumi M, Tamura H: The effects of coffee on conjugation reactions in human colon carcinoma cells. Biol Pharm Bull 2005;28:271-274.
9. Naganuma M, Saruwatari A, Okamura S, Tamura H: Turmeric and curcumin modulate the conjugation of 1-naphthol in Caco-2 cells. Biol Pharm Bull 2006;29:1476-1479.
10. Gan LS, Thakker DR: Applications of the Caco-2 model in the design and development of orally active drugs: elucidation of biochemical and physical barriers posed by the intestinal epithelium. Adv Drug Deliv Rev 1997;23:77-98.
11. Tanaka T, Nonaka G, Nishioka I: Tannins and related compounds. XL. Revision of the structures of punicalin and punicalagin, and isolation and characterization of 2-O-galloylpunicalin from the bark of Punica granatum L. Chem Pharm Bull 1986;34:656-663.
12. Foldes A, Meek JL: Rat brain phenolsulfotransferase: partial purification and some properties. Biochim Biophys Acta 1973;327:365-374.
13. Higuchi, R, Fockler C, Dollinger G, Watson R: Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology 1993;11:1026-1030.
14. Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA: Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem 2000;48:4581-4589.
15. Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D: Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. J Agric Food Chem 2006;54:980-985.
16. Zhou S, Gao Y, Jiang W, Huang M, Xu A, Paxton JW: Interactions of herbs with cytochrome P450. Drug Metab Rev 2003;35:35-98.
17. Venkataramanan R, Komoroski B, Strom S: In vitro and in vivo assessment of herb drug interactions. Life Sci 2006;78:2105-2115.
18. Nagata K, Yamazoe Y: Pharmacogenetics of sulfotransferase. Annu Rev Pharmacol Toxicol 2000;40:159-176.
19. Imai Y, Asada S, Tsukahara S, Ishikawa E, Tsuruo T, Sugimoto Y: Breast cancer resistance protein exports sulfated estrogens but not free estrogens. Mol Pharmacol 2003;64:610-618.
20. Zhou S, Lin LY, Chowbay B: Herbal modulation of P-glycoprotein. Drug Metab Rev 2004;36:57-104.
21. Hadjeri M, Barbier M, Ronot X, Mariotte AM, Boumendjel A, Boutonnat J: Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues. J Med Chem 2003;46:2125-2131.
22. Falany CN: Molecular enzymology of human liver cytosolic sulfotransferases. FASEB J 1991;12:255-259.
23. Podder SK, Nakashima M, Nakamura T, Sasaki H, Nakamura J, Shibasaki J: Conjugation of salicylamide in the intestine wall of dogs and rabbits. J Pharmacobiodyn 1986;9:917-922.
24. Kern SN, Bennett RN, Needs PW, Mellon FA, Kroon PA, Garcia-Conesa MT: Characterization of metabolites of hydroxycinnamates in the in vitro model of human small intestinal epithelium Caco-2 cells. J Agric Food Chem 2003;51:7884-7891.