Metal-free, mild, nonepimerizing, chemo- and enantio- or diastereoselective N-alkylation of amines by alcohols via oxidation/imine-iminium formation/reductive amination: A pragmatic synthesis of octahydropyrazinopyridoindoles and higher ring analogues

Journal of Organic Chemistry

Volumn 78, Issue 23, 2013, Pages 11656-11669

  Khan, Imran A ^a   Saxena, Anil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACID CATALYSIS; ACID CATALYST; CHIRAL AMINES; DIASTEREOSELECTIVE; ENANTIOSELECTIVE; NON-ENZYMATIC; NONENZYMATIC KINETIC RESOLUTIONS; OPTIMIZED CONDITIONS;

AMINES;

ENANTIOSELECTIVITY;

ALCOHOL DERIVATIVE; AMINE; CARBOLINE DERIVATIVE; IMINE; METAL; OCTAHYDROPYRAZINOPYRIDOINDOLE; PHOSPHORIC ACID; UNCLASSIFIED DRUG;

ALKYLATION; AMINATION; ARTICLE; CATALYSIS; ENANTIOSELECTIVITY; EPIMERIZATION; NUCLEOPHILICITY; OXIDATION; REACTION TIME; STEREOCHEMISTRY; SYNTHESIS; TEMPERATURE;

ALCOHOLS; ALKYLATION; AMINATION; AMINES; IMINES; INDOLES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PYRAZINES; PYRIDINES; STEREOISOMERISM;

EID: 84890216937     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo4012249     Document Type: Article

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