메뉴 건너뛰기




Volumn 37, Issue 10, 2013, Pages 2424-2437

Genes and environments in schizophrenia: The different pieces of a manifold puzzle

Author keywords

CNV; Environment; Gene environment interaction; Genetic; In vitro disease modeling; Next generation sequencing; Schizophrenia; SNP

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CANNABIS; DEXTRO AMINO ACID OXIDASE ACTIVATOR; DOPAMINE TRANSPORTER; DYSBINDIN; ENZYME ACTIVATOR; GLUTAMATE RECEPTOR 3; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN; MATRIX METALLOPROTEINASE 16; MICRORNA; MICRORNA 137; NEU DIFFERENTIATION FACTOR; NEUROGRANIN; PROTEIN KINASE B; RGS4 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 4; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 84890144483     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2013.04.010     Document Type: Review
Times cited : (47)

References (148)
  • 1
    • 84877012641 scopus 로고    scopus 로고
    • Childhood adversity and psychosis: examining whether the association is due to genetic confounding using a monozygotic twin differences approach
    • Alemany S., Goldberg X., van Winkel R., Gasto C., Peralta V., Fananas L. Childhood adversity and psychosis: examining whether the association is due to genetic confounding using a monozygotic twin differences approach. Eur. Psychiatry 2012, 10.1016/j.eurpsy.2012.03.001.
    • (2012) Eur. Psychiatry
    • Alemany, S.1    Goldberg, X.2    van Winkel, R.3    Gasto, C.4    Peralta, V.5    Fananas, L.6
  • 3
    • 33749063363 scopus 로고    scopus 로고
    • Modeling madness in mice: one piece at a time
    • Arguello P.A., Gogos J.A. Modeling madness in mice: one piece at a time. Neuron 2006, 52:179-196.
    • (2006) Neuron , vol.52 , pp. 179-196
    • Arguello, P.A.1    Gogos, J.A.2
  • 4
    • 78651275279 scopus 로고    scopus 로고
    • Childhood trauma and children's emerging psychotic symptoms: a genetically sensitive longitudinal cohort study
    • Arseneault L., Cannon M., Fisher H.L., Polanczyk G., Moffitt T.E., Caspi A. Childhood trauma and children's emerging psychotic symptoms: a genetically sensitive longitudinal cohort study. Am. J. Psychiatry 2011, 168:65-72.
    • (2011) Am. J. Psychiatry , vol.168 , pp. 65-72
    • Arseneault, L.1    Cannon, M.2    Fisher, H.L.3    Polanczyk, G.4    Moffitt, T.E.5    Caspi, A.6
  • 5
    • 0037164390 scopus 로고    scopus 로고
    • Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
    • Arseneault L., Cannon M., Poulton R., Murray R., Caspi A., Moffitt T.E. Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ 2002, 325:1212-1213.
    • (2002) BMJ , vol.325 , pp. 1212-1213
    • Arseneault, L.1    Cannon, M.2    Poulton, R.3    Murray, R.4    Caspi, A.5    Moffitt, T.E.6
  • 6
    • 69249229726 scopus 로고    scopus 로고
    • Animal models of gene-environment interactions in schizophrenia
    • Ayhan Y., Sawa A., Ross C.A., Pletnikov M.V. Animal models of gene-environment interactions in schizophrenia. Behav. Brain Res. 2009, 204:274-281.
    • (2009) Behav. Brain Res. , vol.204 , pp. 274-281
    • Ayhan, Y.1    Sawa, A.2    Ross, C.A.3    Pletnikov, M.V.4
  • 10
  • 11
    • 77955379566 scopus 로고    scopus 로고
    • Copy number variations in schizophrenia: critical review and new perspectives on concepts of genetics and disease
    • Bassett A.S., Scherer S.W., Brzustowicz L.M. Copy number variations in schizophrenia: critical review and new perspectives on concepts of genetics and disease. Am. J. Psychiatry 2010, 167:899-914.
    • (2010) Am. J. Psychiatry , vol.167 , pp. 899-914
    • Bassett, A.S.1    Scherer, S.W.2    Brzustowicz, L.M.3
  • 13
    • 84870053882 scopus 로고    scopus 로고
    • Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of delta-9-tetrahydrocannabinol on midbrain and striatal function
    • Bhattacharyya S., Atakan Z., Martin-Santos R., Crippa J.A., Kambeitz J., Prata D., Williams S., Brammer M., Collier D.A., McGuire P.K. Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of delta-9-tetrahydrocannabinol on midbrain and striatal function. Mol. Psychiatry 2012, 17:1152-1155.
    • (2012) Mol. Psychiatry , vol.17 , pp. 1152-1155
    • Bhattacharyya, S.1    Atakan, Z.2    Martin-Santos, R.3    Crippa, J.A.4    Kambeitz, J.5    Prata, D.6    Williams, S.7    Brammer, M.8    Collier, D.A.9    McGuire, P.K.10
  • 14
    • 80051918472 scopus 로고    scopus 로고
    • The genetics of cognitive impairment in schizophrenia: a phenomic perspective
    • Bilder R.M., Howe A., Novak N., Sabb F.W., Parker D.S. The genetics of cognitive impairment in schizophrenia: a phenomic perspective. Trends Cogn. Sci. 2011, 15:428-435.
    • (2011) Trends Cogn. Sci. , vol.15 , pp. 428-435
    • Bilder, R.M.1    Howe, A.2    Novak, N.3    Sabb, F.W.4    Parker, D.S.5
  • 15
    • 70350459011 scopus 로고    scopus 로고
    • Understanding the role of DISC1 in psychiatric disease and during normal development
    • Brandon N.J., Millar J.K., Korth C., Sive H., Singh K.K., Sawa A. Understanding the role of DISC1 in psychiatric disease and during normal development. J. Neurosci. 2009, 29:12768-12775.
    • (2009) J. Neurosci. , vol.29 , pp. 12768-12775
    • Brandon, N.J.1    Millar, J.K.2    Korth, C.3    Sive, H.4    Singh, K.K.5    Sawa, A.6
  • 17
    • 78249256348 scopus 로고    scopus 로고
    • The environment and susceptibility to schizophrenia
    • Brown A.S. The environment and susceptibility to schizophrenia. Prog. Neurobiol. 2011, 93:23-58.
    • (2011) Prog. Neurobiol. , vol.93 , pp. 23-58
    • Brown, A.S.1
  • 20
    • 11844301246 scopus 로고    scopus 로고
    • Schizophrenia and migration: a meta-analysis and review
    • Cantor-Graae E., Selten J.P. Schizophrenia and migration: a meta-analysis and review. Am. J. Psychiatry 2005, 162:12-24.
    • (2005) Am. J. Psychiatry , vol.162 , pp. 12-24
    • Cantor-Graae, E.1    Selten, J.P.2
  • 22
    • 33745684557 scopus 로고    scopus 로고
    • Gene-environment interactions in psychiatry: joining forces with neuroscience
    • Caspi A., Moffitt T.E. Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat. Rev. Neurosci. 2006, 7:583-590.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 583-590
    • Caspi, A.1    Moffitt, T.E.2
  • 23
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene×environment interaction
    • Caspi A., Moffitt T.E., Cannon M., McClay J., Murray R., Harrington H., Taylor A., Arseneault L., Williams B., Braithwaite A., Poulton R., Craig I.W. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene×environment interaction. Biol. Psychiatry 2005, 57:1117-1127.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3    McClay, J.4    Murray, R.5    Harrington, H.6    Taylor, A.7    Arseneault, L.8    Williams, B.9    Braithwaite, A.10    Poulton, R.11    Craig, I.W.12
  • 26
    • 33745473238 scopus 로고    scopus 로고
    • Genetic mouse models of schizophrenia: from hypothesis-based to susceptibility gene-based models
    • Chen J., Lipska B.K., Weinberger D.R. Genetic mouse models of schizophrenia: from hypothesis-based to susceptibility gene-based models. Biol. Psychiatry 2006, 59:1180-1188.
    • (2006) Biol. Psychiatry , vol.59 , pp. 1180-1188
    • Chen, J.1    Lipska, B.K.2    Weinberger, D.R.3
  • 27
    • 79953048441 scopus 로고    scopus 로고
    • Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation
    • Chiang C.H., Su Y., Wen Z., Yoritomo N., Ross C.A., Margolis R.L., Song H., Ming G.L. Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Mol. Psychiatry 2011, 16:358-360.
    • (2011) Mol. Psychiatry , vol.16 , pp. 358-360
    • Chiang, C.H.1    Su, Y.2    Wen, Z.3    Yoritomo, N.4    Ross, C.A.5    Margolis, R.L.6    Song, H.7    Ming, G.L.8
  • 28
    • 69949109765 scopus 로고    scopus 로고
    • Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia
    • Clarke M.C., Tanskanen A., Huttunen M., Whittaker J.C., Cannon M. Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia. Am. J. Psychiatry 2009, 166:1025-1030.
    • (2009) Am. J. Psychiatry , vol.166 , pp. 1025-1030
    • Clarke, M.C.1    Tanskanen, A.2    Huttunen, M.3    Whittaker, J.C.4    Cannon, M.5
  • 29
    • 77956636824 scopus 로고    scopus 로고
    • Genome-wide association studies: a primer
    • Corvin A., Craddock N., Sullivan P.F. Genome-wide association studies: a primer. Psychol. Med. 2010, 40:1063-1077.
    • (2010) Psychol. Med. , vol.40 , pp. 1063-1077
    • Corvin, A.1    Craddock, N.2    Sullivan, P.F.3
  • 36
    • 0017576627 scopus 로고
    • The need for a new medical model: a challenge for biomedicine
    • Engel G.L. The need for a new medical model: a challenge for biomedicine. Science 1977, 196:129-136.
    • (1977) Science , vol.196 , pp. 129-136
    • Engel, G.L.1
  • 38
    • 78649908087 scopus 로고    scopus 로고
    • The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis
    • Fett A.K., Viechtbauer W., Dominguez M.D., Penn D.L., van Os J., Krabbendam L. The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: a meta-analysis. Neurosci. Biobehav. Rev. 2011, 35:573-588.
    • (2011) Neurosci. Biobehav. Rev. , vol.35 , pp. 573-588
    • Fett, A.K.1    Viechtbauer, W.2    Dominguez, M.D.3    Penn, D.L.4    van Os, J.5    Krabbendam, L.6
  • 41
  • 43
    • 79951497637 scopus 로고    scopus 로고
    • Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: an analysis of patient-sibling and sibling-control pairs
    • Genetic Risk and Outcome in Psychosis (GROUP) Investigators
    • Genetic Risk and Outcome in Psychosis (GROUP) Investigators Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: an analysis of patient-sibling and sibling-control pairs. Arch. Gen. Psychiatry 2011, 68:138-147.
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 138-147
  • 45
    • 85028094366 scopus 로고    scopus 로고
    • Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia
    • Green M.J., Cairns M.J., Wu J., Dragovic M., Jablensky A., Tooney P.A., Scott R.J., Carr V.J. Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia. Mol. Psychiatry 2012, 10.1038/mp.2013.48.
    • (2012) Mol. Psychiatry
    • Green, M.J.1    Cairns, M.J.2    Wu, J.3    Dragovic, M.4    Jablensky, A.5    Tooney, P.A.6    Scott, R.J.7    Carr, V.J.8
  • 47
    • 78149461645 scopus 로고    scopus 로고
    • Reduced cortical thickness as an outcome of differential sensitivity to environmental risks in schizophrenia
    • Habets P., Marcelis M., Gronenschild E., Drukker M., van Os J. Reduced cortical thickness as an outcome of differential sensitivity to environmental risks in schizophrenia. Biol. Psychiatry 2011, 69:487-494.
    • (2011) Biol. Psychiatry , vol.69 , pp. 487-494
    • Habets, P.1    Marcelis, M.2    Gronenschild, E.3    Drukker, M.4    van Os, J.5
  • 49
    • 11244260452 scopus 로고    scopus 로고
    • Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people
    • Henquet C., Krabbendam L., Spauwen J., Kaplan C., Lieb R., Wittchen H.U., van Os J. Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people. BMJ 2005, 330:11.
    • (2005) BMJ , vol.330 , pp. 11
    • Henquet, C.1    Krabbendam, L.2    Spauwen, J.3    Kaplan, C.4    Lieb, R.5    Wittchen, H.U.6    van Os, J.7
  • 50
    • 24344470642 scopus 로고    scopus 로고
    • The environment and schizophrenia: the role of cannabis use
    • Henquet C., Murray R., Linszen D., van Os J. The environment and schizophrenia: the role of cannabis use. Schizophr. Bull. 2005, 31:608-612.
    • (2005) Schizophr. Bull. , vol.31 , pp. 608-612
    • Henquet, C.1    Murray, R.2    Linszen, D.3    van Os, J.4
  • 51
    • 58449110608 scopus 로고    scopus 로고
    • COMT ValMet moderation of cannabis-induced psychosis: a momentary assessment study of 'switching on' hallucinations in the flow of daily life
    • Henquet C., Rosa A., Delespaul P., Papiol S., Fananas L., van Os J., Myin-Germeys I. COMT ValMet moderation of cannabis-induced psychosis: a momentary assessment study of 'switching on' hallucinations in the flow of daily life. Acta Psychiatr. Scand. 2009, 119:156-160.
    • (2009) Acta Psychiatr. Scand. , vol.119 , pp. 156-160
    • Henquet, C.1    Rosa, A.2    Delespaul, P.3    Papiol, S.4    Fananas, L.5    van Os, J.6    Myin-Germeys, I.7
  • 52
    • 33751119258 scopus 로고    scopus 로고
    • An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognition
    • Henquet C., Rosa A., Krabbendam L., Papiol S., Fananas L., Drukker M., Ramaekers J.G., van Os J. An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognition. Neuropsychopharmacology 2006, 31:2748-2757.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2748-2757
    • Henquet, C.1    Rosa, A.2    Krabbendam, L.3    Papiol, S.4    Fananas, L.5    Drukker, M.6    Ramaekers, J.G.7    van Os, J.8
  • 53
    • 42949114052 scopus 로고    scopus 로고
    • The coherence of the evidence linking cannabis with psychosis
    • [author reply 462-464]
    • Henquet C., Van Os J. The coherence of the evidence linking cannabis with psychosis. Psychol. Med. 2008, 38:461-462. [author reply 462-464].
    • (2008) Psychol. Med. , vol.38 , pp. 461-462
    • Henquet, C.1    Van Os, J.2
  • 56
    • 78149428430 scopus 로고    scopus 로고
    • Rethinking schizophrenia
    • Insel T.R. Rethinking schizophrenia. Nature 2010, 468:187-193.
    • (2010) Nature , vol.468 , pp. 187-193
    • Insel, T.R.1
  • 58
    • 77950614376 scopus 로고    scopus 로고
    • Suppression of the P50 evoked response and neuregulin 1-induced AKT phosphorylation in first-episode schizophrenia
    • Keri S., Beniczky S., Kelemen O. Suppression of the P50 evoked response and neuregulin 1-induced AKT phosphorylation in first-episode schizophrenia. Am. J. Psychiatry 2010, 167:444-450.
    • (2010) Am. J. Psychiatry , vol.167 , pp. 444-450
    • Keri, S.1    Beniczky, S.2    Kelemen, O.3
  • 59
    • 58549098047 scopus 로고    scopus 로고
    • Effects of a neuregulin 1 variant on conversion to schizophrenia and schizophreniform disorder in people at high risk for psychosis
    • Keri S., Kiss I., Kelemen O. Effects of a neuregulin 1 variant on conversion to schizophrenia and schizophreniform disorder in people at high risk for psychosis. Mol. Psychiatry 2009, 14:118-119.
    • (2009) Mol. Psychiatry , vol.14 , pp. 118-119
    • Keri, S.1    Kiss, I.2    Kelemen, O.3
  • 60
    • 63449100784 scopus 로고    scopus 로고
    • A polymorphism of the neuregulin 1 gene (SNP8NRG243177/rs6994992) affects reactivity to expressed emotion in schizophrenia
    • Keri S., Kiss I., Seres I., Kelemen O. A polymorphism of the neuregulin 1 gene (SNP8NRG243177/rs6994992) affects reactivity to expressed emotion in schizophrenia. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 2009, 150B:418-420.
    • (2009) Am. J. Med. Genet. B: Neuropsychiatr. Genet. , vol.150 B , pp. 418-420
    • Keri, S.1    Kiss, I.2    Seres, I.3    Kelemen, O.4
  • 63
    • 84857239381 scopus 로고    scopus 로고
    • Decreased peripheral expression of neuregulin 1 in high-risk individuals who later converted to psychosis
    • Kiss I., Kelemen O., Keri S. Decreased peripheral expression of neuregulin 1 in high-risk individuals who later converted to psychosis. Schizophr. Res. 2012, 135:198-199.
    • (2012) Schizophr. Res. , vol.135 , pp. 198-199
    • Kiss, I.1    Kelemen, O.2    Keri, S.3
  • 65
    • 80051781237 scopus 로고    scopus 로고
    • Replication in two independent population-based samples that childhood maltreatment and cannabis use synergistically impact on psychosis risk
    • Konings M., Stefanis N., Kuepper R., de Graaf R., Have M.T., van Os J., Bakoula C., Henquet C. Replication in two independent population-based samples that childhood maltreatment and cannabis use synergistically impact on psychosis risk. Psychol. Med. 2011, 1-11.
    • (2011) Psychol. Med. , pp. 1-11
    • Konings, M.1    Stefanis, N.2    Kuepper, R.3    de Graaf, R.4    Have, M.T.5    van Os, J.6    Bakoula, C.7    Henquet, C.8
  • 66
    • 81055157018 scopus 로고    scopus 로고
    • Studying the epigenome using next generation sequencing
    • Ku C.S., Naidoo N., Wu M., Soong R. Studying the epigenome using next generation sequencing. J. Med. Genet. 2011, 48:721-730.
    • (2011) J. Med. Genet. , vol.48 , pp. 721-730
    • Ku, C.S.1    Naidoo, N.2    Wu, M.3    Soong, R.4
  • 67
    • 84890198205 scopus 로고    scopus 로고
    • Do cannabis and urbanicity co-participate in causing psychosis? Evidence from a 10-year follow-up cohort study
    • Kuepper R., van Os J., Lieb R., Wittchen H.U., Henquet C. Do cannabis and urbanicity co-participate in causing psychosis? Evidence from a 10-year follow-up cohort study. Psychol. Med. 2011, 1-9.
    • (2011) Psychol. Med. , pp. 1-9
    • Kuepper, R.1    van Os, J.2    Lieb, R.3    Wittchen, H.U.4    Henquet, C.5
  • 68
    • 79952276116 scopus 로고    scopus 로고
    • Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study
    • Kuepper R., van Os J., Lieb R., Wittchen H.U., Hofler M., Henquet C. Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study. BMJ 2011, 342:d738.
    • (2011) BMJ , vol.342
    • Kuepper, R.1    van Os, J.2    Lieb, R.3    Wittchen, H.U.4    Hofler, M.5    Henquet, C.6
  • 69
    • 84871270974 scopus 로고    scopus 로고
    • Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets
    • Kwon E., Wang W., Tsai L.H. Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets. Mol. Psychiatry 2013, 18:11-12.
    • (2013) Mol. Psychiatry , vol.18 , pp. 11-12
    • Kwon, E.1    Wang, W.2    Tsai, L.H.3
  • 70
    • 33748474553 scopus 로고    scopus 로고
    • Pathophysiologically based treatment interventions in schizophrenia
    • Lewis D.A., Gonzalez-Burgos G. Pathophysiologically based treatment interventions in schizophrenia. Nat. Med. 2006, 12:1016-1022.
    • (2006) Nat. Med. , vol.12 , pp. 1016-1022
    • Lewis, D.A.1    Gonzalez-Burgos, G.2
  • 72
    • 84858434210 scopus 로고    scopus 로고
    • CNVs: harbingers of a rare variant revolution in psychiatric genetics
    • Malhotra D., Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 2012, 148:1223-1241.
    • (2012) Cell , vol.148 , pp. 1223-1241
    • Malhotra, D.1    Sebat, J.2
  • 73
    • 77953879152 scopus 로고    scopus 로고
    • Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases
    • Marchetto M.C., Winner B., Gage F.H. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum. Mol. Genet. 2010, 19:R71-R76.
    • (2010) Hum. Mol. Genet. , vol.19
    • Marchetto, M.C.1    Winner, B.2    Gage, F.H.3
  • 79
    • 33645502924 scopus 로고    scopus 로고
    • Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts
    • Mill J., Caspi A., Williams B.S., Craig I., Taylor A., Polo-Tomas M., Berridge C.W., Poulton R., Moffitt T.E. Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts. Arch. Gen. Psychiatry 2006, 63:462-469.
    • (2006) Arch. Gen. Psychiatry , vol.63 , pp. 462-469
    • Mill, J.1    Caspi, A.2    Williams, B.S.3    Craig, I.4    Taylor, A.5    Polo-Tomas, M.6    Berridge, C.W.7    Poulton, R.8    Moffitt, T.E.9
  • 80
    • 34447619511 scopus 로고    scopus 로고
    • Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
    • Moore T.H., Zammit S., Lingford-Hughes A., Barnes T.R., Jones P.B., Burke M., Lewis G. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet 2007, 370:319-328.
    • (2007) Lancet , vol.370 , pp. 319-328
    • Moore, T.H.1    Zammit, S.2    Lingford-Hughes, A.3    Barnes, T.R.4    Jones, P.B.5    Burke, M.6    Lewis, G.7
  • 81
    • 84871267120 scopus 로고    scopus 로고
    • The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants
    • Mowry B.J., Gratten J. The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants. Mol. Psychiatry 2013, 18:38-52.
    • (2013) Mol. Psychiatry , vol.18 , pp. 38-52
    • Mowry, B.J.1    Gratten, J.2
  • 83
    • 79952165893 scopus 로고    scopus 로고
    • From environment to therapy in psychosis: a real-world momentary assessment approach
    • Myin-Germeys I., Birchwood M., Kwapil T. From environment to therapy in psychosis: a real-world momentary assessment approach. Schizophr. Bull. 2011, 37:244-247.
    • (2011) Schizophr. Bull. , vol.37 , pp. 244-247
    • Myin-Germeys, I.1    Birchwood, M.2    Kwapil, T.3
  • 87
    • 33846363929 scopus 로고    scopus 로고
    • Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia
    • Nicodemus K.K., Kolachana B.S., Vakkalanka R., Straub R.E., Giegling I., Egan M.F., Rujescu D., Weinberger D.R. Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia. Hum. Genet. 2007, 120:889-906.
    • (2007) Hum. Genet. , vol.120 , pp. 889-906
    • Nicodemus, K.K.1    Kolachana, B.S.2    Vakkalanka, R.3    Straub, R.E.4    Giegling, I.5    Egan, M.F.6    Rujescu, D.7    Weinberger, D.R.8
  • 88
    • 45349094387 scopus 로고    scopus 로고
    • Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk
    • Nicodemus K.K., Marenco S., Batten A.J., Vakkalanka R., Egan M.F., Straub R.E., Weinberger D.R. Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk. Mol. Psychiatry 2008, 13:873-877.
    • (2008) Mol. Psychiatry , vol.13 , pp. 873-877
    • Nicodemus, K.K.1    Marenco, S.2    Batten, A.J.3    Vakkalanka, R.4    Egan, M.F.5    Straub, R.E.6    Weinberger, D.R.7
  • 90
    • 54249154624 scopus 로고    scopus 로고
    • Environmental studies of schizophrenia through the prism of epigenetics
    • Oh G., Petronis A. Environmental studies of schizophrenia through the prism of epigenetics. Schizophr. Bull. 2008, 34:1122-1129.
    • (2008) Schizophr. Bull. , vol.34 , pp. 1122-1129
    • Oh, G.1    Petronis, A.2
  • 92
    • 79960535703 scopus 로고    scopus 로고
    • Challenges of analysing gene-environment interactions in mouse models of schizophrenia
    • Oliver P.L. Challenges of analysing gene-environment interactions in mouse models of schizophrenia. ScientificWorldJournal 2011, 11:1411-1420.
    • (2011) ScientificWorldJournal , vol.11 , pp. 1411-1420
    • Oliver, P.L.1
  • 93
    • 0035158090 scopus 로고    scopus 로고
    • Evidence of a dose-response relationship between urbanicity during upbringing and schizophrenia risk
    • Pedersen C.B., Mortensen P.B. Evidence of a dose-response relationship between urbanicity during upbringing and schizophrenia risk. Arch. Gen. Psychiatry 2001, 58:1039-1046.
    • (2001) Arch. Gen. Psychiatry , vol.58 , pp. 1039-1046
    • Pedersen, C.B.1    Mortensen, P.B.2
  • 97
    • 79955463764 scopus 로고    scopus 로고
    • The effects of cannabis use on neurocognition in schizophrenia: a meta-analysis
    • Rabin R.A., Zakzanis K.K., George T.P. The effects of cannabis use on neurocognition in schizophrenia: a meta-analysis. Schizophr. Res. 2011, 128:111-116.
    • (2011) Schizophr. Res. , vol.128 , pp. 111-116
    • Rabin, R.A.1    Zakzanis, K.K.2    George, T.P.3
  • 103
    • 70449732249 scopus 로고    scopus 로고
    • Rare structural variants in schizophrenia: one disorder, multiple mutations: one mutation, multiple disorders
    • Sebat J., Levy D.L., McCarthy S.E. Rare structural variants in schizophrenia: one disorder, multiple mutations: one mutation, multiple disorders. Trends Genet. 2009, 25:528-535.
    • (2009) Trends Genet. , vol.25 , pp. 528-535
    • Sebat, J.1    Levy, D.L.2    McCarthy, S.E.3
  • 104
    • 23744475787 scopus 로고    scopus 로고
    • Social defeat: risk factor for schizophrenia?
    • Selten J.P., Cantor-Graae E. Social defeat: risk factor for schizophrenia?. Br. J. Psychiatry 2005, 187:101-102.
    • (2005) Br. J. Psychiatry , vol.187 , pp. 101-102
    • Selten, J.P.1    Cantor-Graae, E.2
  • 105
    • 70349792000 scopus 로고    scopus 로고
    • MHC class I: an unexpected role in neuronal plasticity
    • Shatz C.J. MHC class I: an unexpected role in neuronal plasticity. Neuron 2009, 64:40-45.
    • (2009) Neuron , vol.64 , pp. 40-45
    • Shatz, C.J.1
  • 111
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies
    • Sullivan P.F., Kendler K.S., Neale M.C. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch. Gen. Psychiatry 2003, 60:1187-1192.
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 116
    • 0037362632 scopus 로고    scopus 로고
    • Do urbanicity and familial liability coparticipate in causing psychosis?
    • van Os J., Hanssen M., Bak M., Bijl R.V., Vollebergh W. Do urbanicity and familial liability coparticipate in causing psychosis?. Am. J. Psychiatry 2003, 160:477-482.
    • (2003) Am. J. Psychiatry , vol.160 , pp. 477-482
    • van Os, J.1    Hanssen, M.2    Bak, M.3    Bijl, R.V.4    Vollebergh, W.5
  • 117
    • 68949180394 scopus 로고    scopus 로고
    • Schizophrenia
    • van Os J., Kapur S. Schizophrenia. Lancet 2009, 374:635-645.
    • (2009) Lancet , vol.374 , pp. 635-645
    • van Os, J.1    Kapur, S.2
  • 118
    • 78149462958 scopus 로고    scopus 로고
    • The environment and schizophrenia
    • van Os J., Kenis G., Rutten B.P. The environment and schizophrenia. Nature 2010, 468:203-212.
    • (2010) Nature , vol.468 , pp. 203-212
    • van Os, J.1    Kenis, G.2    Rutten, B.P.3
  • 119
    • 9744272427 scopus 로고    scopus 로고
    • Confirmation of synergy between urbanicity and familial liability in the causation of psychosis
    • van Os J., Pedersen C.B., Mortensen P.B. Confirmation of synergy between urbanicity and familial liability in the causation of psychosis. Am. J. Psychiatry 2004, 161:2312-2314.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 2312-2314
    • van Os, J.1    Pedersen, C.B.2    Mortensen, P.B.3
  • 120
    • 69949099211 scopus 로고    scopus 로고
    • Gene-environment-wide interaction studies in psychiatry
    • van Os J., Rutten B.P. Gene-environment-wide interaction studies in psychiatry. Am. J. Psychiatry 2009, 166:964-966.
    • (2009) Am. J. Psychiatry , vol.166 , pp. 964-966
    • van Os, J.1    Rutten, B.P.2
  • 121
    • 54249166128 scopus 로고    scopus 로고
    • Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions
    • van Os J., Rutten B.P., Poulton R. Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions. Schizophr. Bull. 2008, 34:1066-1082.
    • (2008) Schizophr. Bull. , vol.34 , pp. 1066-1082
    • van Os, J.1    Rutten, B.P.2    Poulton, R.3
  • 122
    • 79951472497 scopus 로고    scopus 로고
    • Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up
    • Genetic Risk and Outcome of Psychosis (GROUP) Investigators
    • Van Winkel R., Esquivel G., Kenis G. Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. Arch. Gen. Psychiatry 2011, 68:148-157. Genetic Risk and Outcome of Psychosis (GROUP) Investigators.
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 148-157
    • Van Winkel, R.1    Esquivel, G.2    Kenis, G.3
  • 125
    • 54249120358 scopus 로고    scopus 로고
    • Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction
    • van Winkel R., Stefanis N.C., Myin-Germeys I. Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction. Schizophr. Bull. 2008, 34:1095-1105.
    • (2008) Schizophr. Bull. , vol.34 , pp. 1095-1105
    • van Winkel, R.1    Stefanis, N.C.2    Myin-Germeys, I.3
  • 127
    • 54249148461 scopus 로고    scopus 로고
    • Which environments for G x E? A user perspective on the roles of trauma and structural discrimination in the onset and course of schizophrenia
    • van Zelst C. Which environments for G x E? A user perspective on the roles of trauma and structural discrimination in the onset and course of schizophrenia. Schizophr. Bull. 2008, 34:1106-1110.
    • (2008) Schizophr. Bull. , vol.34 , pp. 1106-1110
    • van Zelst, C.1
  • 128
    • 64349093999 scopus 로고    scopus 로고
    • Stigma and schizophrenia
    • (author reply 1336-1337)
    • van Zelst C. Stigma and schizophrenia. Lancet 2009, 373:1336. (author reply 1336-1337).
    • (2009) Lancet , vol.373 , pp. 1336
    • van Zelst, C.1
  • 129
    • 64349101569 scopus 로고    scopus 로고
    • Stigmatization as an environmental risk in schizophrenia: a user perspective
    • van Zelst C. Stigmatization as an environmental risk in schizophrenia: a user perspective. Schizophr. Bull. 2009, 35:293-296.
    • (2009) Schizophr. Bull. , vol.35 , pp. 293-296
    • van Zelst, C.1
  • 130
    • 84861647648 scopus 로고    scopus 로고
    • Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies
    • Varese F., Smeets F., Drukker M., Lieverse R., Lataster T., Viechtbauer W., Read J., van Os J., Bentall R.P. Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies. Schizophr. Bull. 2012, 38:661-671.
    • (2012) Schizophr. Bull. , vol.38 , pp. 661-671
    • Varese, F.1    Smeets, F.2    Drukker, M.3    Lieverse, R.4    Lataster, T.5    Viechtbauer, W.6    Read, J.7    van Os, J.8    Bentall, R.P.9
  • 140
    • 84862528505 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: past, present, and future
    • Yamanaka S. Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 2012, 10:678-684.
    • (2012) Cell Stem Cell , vol.10 , pp. 678-684
    • Yamanaka, S.1
  • 143
    • 77955893203 scopus 로고    scopus 로고
    • Misconceptions about gene-environment interactions in psychiatry
    • Zammit S., Owen M.J., Lewis G. Misconceptions about gene-environment interactions in psychiatry. Evid. Based Ment. Health 2010, 13:65-68.
    • (2010) Evid. Based Ment. Health , vol.13 , pp. 65-68
    • Zammit, S.1    Owen, M.J.2    Lewis, G.3
  • 145
    • 77952337168 scopus 로고    scopus 로고
    • The study of gene-environment interactions in psychiatry: limited gains at a substantial cost?
    • Zammit S., Wiles N.J., Lewis G. The study of gene-environment interactions in psychiatry: limited gains at a substantial cost?. Psychol. Med. 2010, 40:711-716.
    • (2010) Psychol. Med. , vol.40 , pp. 711-716
    • Zammit, S.1    Wiles, N.J.2    Lewis, G.3
  • 146
    • 79952898021 scopus 로고    scopus 로고
    • Investigating monogenic and complex diseases with pluripotent stem cells
    • Zhu H., Lensch M.W., Cahan P., Daley G.Q. Investigating monogenic and complex diseases with pluripotent stem cells. Nat. Rev. Genet. 2011, 12:266-275.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 266-275
    • Zhu, H.1    Lensch, M.W.2    Cahan, P.3    Daley, G.Q.4
  • 148
    • 0017576536 scopus 로고
    • Vulnerability-a new view of schizophrenia
    • Zubin J., Spring B. Vulnerability-a new view of schizophrenia. J. Abnorm. Psychol. 1977, 86:103-126.
    • (1977) J. Abnorm. Psychol. , vol.86 , pp. 103-126
    • Zubin, J.1    Spring, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.