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Volumn 7, Issue 10, 2012, Pages

Genome-Wide DNA Methylation and Gene Expression Analyses of Monozygotic Twins Discordant for Intelligence Levels

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84867652223     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047081     Document Type: Article
Times cited : (27)

References (52)
  • 1
    • 0034579729 scopus 로고    scopus 로고
    • The stability of individual differences in mental ability from childhood to old age: follow-up of the 1932 scottish mental survey
    • Deary I, Whalley LJ, Lemmon H, Crawford JR, Starr JM, (2000) The stability of individual differences in mental ability from childhood to old age: follow-up of the 1932 scottish mental survey. Intelligence 28: 49-55.
    • (2000) Intelligence , vol.28 , pp. 49-55
    • Deary, I.1    Whalley, L.J.2    Lemmon, H.3    Crawford, J.R.4    Starr, J.M.5
  • 2
    • 84862777111 scopus 로고    scopus 로고
    • Genetic contributions to stability and change in intelligence from childhood to old age
    • Deary IJ, Yang J, Davies G, Harris SE, Tenesa A, et al. (2012) Genetic contributions to stability and change in intelligence from childhood to old age. Nature 482: 212-215.
    • (2012) Nature , vol.482 , pp. 212-215
    • Deary, I.J.1    Yang, J.2    Davies, G.3    Harris, S.E.4    Tenesa, A.5
  • 3
    • 17944377388 scopus 로고    scopus 로고
    • Genetics of cognition: outline of a collaborative twin study
    • Wright M, Geus ED, Ando J, Luciano M, Posthuma D, et al. (2001) Genetics of cognition: outline of a collaborative twin study. Twin Res 4: 48-56.
    • (2001) Twin Res , vol.4 , pp. 48-56
    • Wright, M.1    Geus, E.D.2    Ando, J.3    Luciano, M.4    Posthuma, D.5
  • 4
    • 0034863335 scopus 로고    scopus 로고
    • Heritability estimates of intelligence in twins: effect of chorion type
    • Jacobs N, Gestel SV, Derom C, Thiery E, Vernon P, et al. (2001) Heritability estimates of intelligence in twins: effect of chorion type. Behav Genet 31: 209-217.
    • (2001) Behav Genet , vol.31 , pp. 209-217
    • Jacobs, N.1    Gestel, S.V.2    Derom, C.3    Thiery, E.4    Vernon, P.5
  • 5
    • 67349181687 scopus 로고    scopus 로고
    • A twin study of the genetics of high cognitive ability selected from 11,000 twin pairs in six studies from four countries
    • Haworth CM, Wright MJ, Martin NW, Martin NG, Boomsma DI, et al. (2010) A twin study of the genetics of high cognitive ability selected from 11,000 twin pairs in six studies from four countries. Behav Genet 39: 359-370.
    • (2010) Behav Genet , vol.39 , pp. 359-370
    • Haworth, C.M.1    Wright, M.J.2    Martin, N.W.3    Martin, N.G.4    Boomsma, D.I.5
  • 6
    • 72049114431 scopus 로고    scopus 로고
    • The impact of genetic research on our understanding of normal cognitive ageing: 1995 to 2009
    • Payton A, (2009) The impact of genetic research on our understanding of normal cognitive ageing: 1995 to 2009. Neuropsychol Rev 19: 451-477.
    • (2009) Neuropsychol Rev , vol.19 , pp. 451-477
    • Payton, A.1
  • 7
    • 78650516659 scopus 로고    scopus 로고
    • Life events moderate variation in cognitive ability (g) in adults
    • Vinkhuyzen AA, van der Sluis S, Posthuma D, (2011) Life events moderate variation in cognitive ability (g) in adults. Mol Psychiatry 16: 4-6.
    • (2011) Mol Psychiatry , vol.16 , pp. 4-6
    • Vinkhuyzen, A.A.1    van der Sluis, S.2    Posthuma, D.3
  • 8
    • 1642376040 scopus 로고    scopus 로고
    • Molecular and comparative genetics of mental retardation
    • Inlow JK, Restifo LL, (2004) Molecular and comparative genetics of mental retardation. Genetics 166: 835-881.
    • (2004) Genetics , vol.166 , pp. 835-881
    • Inlow, J.K.1    Restifo, L.L.2
  • 9
    • 80053132878 scopus 로고    scopus 로고
    • Genome-wide association studies establish that human intelligence is highly heritable and polygenic
    • Davies G, Tenesa A, Payton A, Yang J, Harris SE, et al. (2011) Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry 16: 996-1005.
    • (2011) Mol Psychiatry , vol.16 , pp. 996-1005
    • Davies, G.1    Tenesa, A.2    Payton, A.3    Yang, J.4    Harris, S.E.5
  • 10
    • 40849109768 scopus 로고    scopus 로고
    • Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
    • Bruder CE, Piotrowski A, Gijsbers AA, Andersson R, Erickson S, et al. (2008) Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am J Hum Genet 82: 763-771.
    • (2008) Am J Hum Genet , vol.82 , pp. 763-771
    • Bruder, C.E.1    Piotrowski, A.2    Gijsbers, A.A.3    Andersson, R.4    Erickson, S.5
  • 11
    • 0030661935 scopus 로고    scopus 로고
    • De novo 14484 mitochondrial DNA mutation in monozygotic twins discordant for Leber's hereditary optic neuropathy
    • Biousse V, Brown MD, Newman NJ, Allen JC, Rosenfeld J, et al. (1997) De novo 14484 mitochondrial DNA mutation in monozygotic twins discordant for Leber's hereditary optic neuropathy. Neurology 49: 1136-1138.
    • (1997) Neurology , vol.49 , pp. 1136-1138
    • Biousse, V.1    Brown, M.D.2    Newman, N.J.3    Allen, J.C.4    Rosenfeld, J.5
  • 12
    • 77951836633 scopus 로고    scopus 로고
    • Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis
    • Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, et al. (2010) Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature 464: 1351-1356.
    • (2010) Nature , vol.464 , pp. 1351-1356
    • Baranzini, S.E.1    Mudge, J.2    van Velkinburgh, J.C.3    Khankhanian, P.4    Khrebtukova, I.5
  • 13
    • 77956224313 scopus 로고    scopus 로고
    • Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking
    • Haggarty P, Hoad G, Harris SE, Starr JM, Fox HC, et al. (2010) Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking. PLoS One 5: e11329.
    • (2010) PLoS One , vol.5
    • Haggarty, P.1    Hoad, G.2    Harris, S.E.3    Starr, J.M.4    Fox, H.C.5
  • 14
    • 34548138278 scopus 로고    scopus 로고
    • Epigenetics: A Historical Overview
    • Holliday R, (2006) Epigenetics: A Historical Overview. Epigenetics 1: 76-80.
    • (2006) Epigenetics , vol.1 , pp. 76-80
    • Holliday, R.1
  • 15
    • 75649151209 scopus 로고    scopus 로고
    • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
    • Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, et al. (2010) Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 20: 170-179.
    • (2010) Genome Res , vol.20 , pp. 170-179
    • Javierre, B.M.1    Fernandez, A.F.2    Richter, J.3    Al-Shahrour, F.4    Martin-Subero, J.I.5
  • 17
    • 0003060607 scopus 로고
    • Genetics and intelligence: recent data
    • Plomin R, Defries JC, (1980) Genetics and intelligence: recent data. Intelligence 4: 15-24.
    • (1980) Intelligence , vol.4 , pp. 15-24
    • Plomin, R.1    Defries, J.C.2
  • 19
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5
  • 20
    • 58749110907 scopus 로고    scopus 로고
    • Cognition in the adults with childhood-onset GH deficiency
    • van Nleuwpoort IC, Drent Ml, (2008) Cognition in the adults with childhood-onset GH deficiency. Eur J Endocrinol 159 (Suppl 1):: S53-57.
    • (2008) Eur J Endocrinol , vol.159 , Issue.SUPPL. 1
    • van Nleuwpoort, I.C.1    Drent, M.2
  • 21
    • 77249137659 scopus 로고    scopus 로고
    • The neuroscience of human intelligence differences
    • Deary IJ, Penke L, Johnson W, (2010) The neuroscience of human intelligence differences. Nat Rev Neurosci 11: 201-211.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 201-211
    • Deary, I.J.1    Penke, L.2    Johnson, W.3
  • 22
    • 64949128862 scopus 로고    scopus 로고
    • Is g an entity? A Japanese twin study using syllogisms and intelligence tests
    • Shikishima C, Hiraishi K, Yamagata S, Sugimoto Y, Takemura R, et al. (2009) Is g an entity? A Japanese twin study using syllogisms and intelligence tests. Intelligence 37: 256-267.
    • (2009) Intelligence , vol.37 , pp. 256-267
    • Shikishima, C.1    Hiraishi, K.2    Yamagata, S.3    Sugimoto, Y.4    Takemura, R.5
  • 23
    • 79952104806 scopus 로고    scopus 로고
    • A twin approach to unraveling epigenetics
    • Bell JT, Spector TD, (2011) A twin approach to unraveling epigenetics. Trends Genet 27: 116-125.
    • (2011) Trends Genet , vol.27 , pp. 116-125
    • Bell, J.T.1    Spector, T.D.2
  • 24
  • 25
    • 80054683063 scopus 로고    scopus 로고
    • ARHGAP18, a GTPase-activating protein for Rho A, controls cell shape, spreading, and motility
    • Maeda M, Hasegawa H, Hyodo T, Ito S, Asano E, et al. (2011) ARHGAP18, a GTPase-activating protein for Rho A, controls cell shape, spreading, and motility. Mol Biol Cell 22: 3840-3852.
    • (2011) Mol Biol Cell , vol.22 , pp. 3840-3852
    • Maeda, M.1    Hasegawa, H.2    Hyodo, T.3    Ito, S.4    Asano, E.5
  • 26
    • 1842455769 scopus 로고    scopus 로고
    • The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
    • Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, et al. (2004) The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci 7: 364-372.
    • (2004) Nat Neurosci , vol.7 , pp. 364-372
    • Govek, E.E.1    Newey, S.E.2    Akerman, C.J.3    Cross, J.R.4    van der Veken, L.5
  • 28
    • 0037466510 scopus 로고    scopus 로고
    • Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants
    • Nishikawa K, Li H, Kawamura R, Osaka H, Wang YL, et al. (2003) Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants. Biochem Biophys Res Commun 304: 176-183.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 176-183
    • Nishikawa, K.1    Li, H.2    Kawamura, R.3    Osaka, H.4    Wang, Y.L.5
  • 29
    • 0037336031 scopus 로고    scopus 로고
    • Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch
    • Karthikeyan S, Zhou Q, Mseeh F, Grishin NV, Osterman AL, et al. (2003) Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch. Structure 11: 265-273.
    • (2003) Structure , vol.11 , pp. 265-273
    • Karthikeyan, S.1    Zhou, Q.2    Mseeh, F.3    Grishin, N.V.4    Osterman, A.L.5
  • 30
    • 23644454808 scopus 로고    scopus 로고
    • Nuclear MRP genes and mitochondrial disease
    • O'Brien TW, O'Brien BJ, Norman RA, (2005) Nuclear MRP genes and mitochondrial disease. Gene 354: 147-151.
    • (2005) Gene , vol.354 , pp. 147-151
    • O'Brien, T.W.1    O'Brien, B.J.2    Norman, R.A.3
  • 31
    • 0141907263 scopus 로고    scopus 로고
    • Plant DNA helicases: the long unwinding road
    • Tuteja N, (2003) Plant DNA helicases: the long unwinding road. J Exp Bot 54: 2201-2214.
    • (2003) J Exp Bot , vol.54 , pp. 2201-2214
    • Tuteja, N.1
  • 32
    • 27544471936 scopus 로고    scopus 로고
    • Ku: a multifunctional protein involved in telomere maintenance
    • Fisher TS, Zakian VA, (2005) Ku: a multifunctional protein involved in telomere maintenance. DNA Repair (Amst) 4: 1215-1226.
    • (2005) DNA Repair (Amst) , vol.4 , pp. 1215-1226
    • Fisher, T.S.1    Zakian, V.A.2
  • 34
    • 25444523445 scopus 로고    scopus 로고
    • Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP
    • Zekri L, Chebli K, Tourrière H, Nielsen FC, Hansen TV, et al. (2005) Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP. Mol Cell Biol 25: 8703-8716.
    • (2005) Mol Cell Biol , vol.25 , pp. 8703-8716
    • Zekri, L.1    Chebli, K.2    Tourrière, H.3    Nielsen, F.C.4    Hansen, T.V.5
  • 35
    • 40849137629 scopus 로고    scopus 로고
    • Effects of the cholinergic agonist nicotine on reorienting of visual spatial attention and top-down attentional control
    • Thiel CM, Fink GR, (2008) Effects of the cholinergic agonist nicotine on reorienting of visual spatial attention and top-down attentional control. Neuroscience 152: 381-390.
    • (2008) Neuroscience , vol.152 , pp. 381-390
    • Thiel, C.M.1    Fink, G.R.2
  • 36
    • 34249999182 scopus 로고    scopus 로고
    • Nicotine gates long-term potentiation in the hippocampal CA1 region via the activation of alpha2* nicotinic ACh receptors
    • Nakauchi S, Brennan RJ, Boulter J, Sumikawa K, (2007) Nicotine gates long-term potentiation in the hippocampal CA1 region via the activation of alpha2* nicotinic ACh receptors. Eur J Neurosci 25: 2666-2681.
    • (2007) Eur J Neurosci , vol.25 , pp. 2666-2681
    • Nakauchi, S.1    Brennan, R.J.2    Boulter, J.3    Sumikawa, K.4
  • 37
    • 0033818515 scopus 로고    scopus 로고
    • Modulation and genetic identification of the M channel
    • Brown BS, Yu SP, (2000) Modulation and genetic identification of the M channel. Prog Biophys Mol Biol 73: 135-166.
    • (2000) Prog Biophys Mol Biol , vol.73 , pp. 135-166
    • Brown, B.S.1    Yu, S.P.2
  • 38
    • 16644379267 scopus 로고    scopus 로고
    • Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior
    • Peters HC, Hu H, Pongs O, Storm JF, Isbrandt D, (2005) Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. Nat Neurosci 8: 51-60.
    • (2005) Nat Neurosci , vol.8 , pp. 51-60
    • Peters, H.C.1    Hu, H.2    Pongs, O.3    Storm, J.F.4    Isbrandt, D.5
  • 40
    • 34447289392 scopus 로고    scopus 로고
    • Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease
    • Rodriguez S, Gaunt TR, Day INM, (2007) Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease. Hum Genet 122: 1-21.
    • (2007) Hum Genet , vol.122 , pp. 1-21
    • Rodriguez, S.1    Gaunt, T.R.2    Day, I.N.M.3
  • 41
    • 19944398817 scopus 로고    scopus 로고
    • SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children
    • Butcher LM, Meaburn E, Knight J, Sham PC, Schalkwyk LC, et al. (2005) SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Hum Mol Genet 14: 1315-1325.
    • (2005) Hum Mol Genet , vol.14 , pp. 1315-1325
    • Butcher, L.M.1    Meaburn, E.2    Knight, J.3    Sham, P.C.4    Schalkwyk, L.C.5
  • 43
    • 70450217879 scopus 로고    scopus 로고
    • Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462: 351-322.
    • (2009) Nature , vol.462 , pp. 322-351
    • Lister, R.1    Pelizzola, M.2    Dowen, R.H.3    Hawkins, R.D.4    Hon, G.5
  • 44
    • 27344436234 scopus 로고    scopus 로고
    • Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia
    • Glatt SJ, Everall IP, Kremen WS, Corbeil J, Sásik R, et al. (2005) Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc Natl Acad Sci U S A 102: 15533-15538.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15533-15538
    • Glatt, S.J.1    Everall, I.P.2    Kremen, W.S.3    Corbeil, J.4    Sásik, R.5
  • 45
    • 77958005855 scopus 로고    scopus 로고
    • Is human blood a good surrogate for brain tissue in transcriptional studies?
    • Cai C, Langfelder P, Fuller TF, Oldham MC, Luo R, et al. (2010) Is human blood a good surrogate for brain tissue in transcriptional studies? BMC Genomics 11: 589.
    • (2010) BMC Genomics , vol.11 , pp. 589
    • Cai, C.1    Langfelder, P.2    Fuller, T.F.3    Oldham, M.C.4    Luo, R.5
  • 47
    • 81855183787 scopus 로고    scopus 로고
    • Disease-associated epigenetic changes in monozygotic twin discordant for schizophrenia and bipolar disorder
    • Dempster EL, Pidsley R, Schalkwyk LC, Owens S, Georgiades A, et al. (2011) Disease-associated epigenetic changes in monozygotic twin discordant for schizophrenia and bipolar disorder. Hum Mol Genet 20: 4786-4796.
    • (2011) Hum Mol Genet , vol.20 , pp. 4786-4796
    • Dempster, E.L.1    Pidsley, R.2    Schalkwyk, L.C.3    Owens, S.4    Georgiades, A.5
  • 48
    • 77955803943 scopus 로고    scopus 로고
    • Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain
    • Nguyen AT, Rauch TA, Pfeifer GP, Hu VW, (2010) Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain. FASEB J 24: 3036-3051.
    • (2010) FASEB J , vol.24 , pp. 3036-3051
    • Nguyen, A.T.1    Rauch, T.A.2    Pfeifer, G.P.3    Hu, V.W.4
  • 49
    • 79960828534 scopus 로고    scopus 로고
    • Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins
    • Sugawara H, Iwamoto K, Bundo M, Ueda J, Miyauchi T, et al. (2011) Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins. Transl Psychiatry 1: e24.
    • (2011) Transl Psychiatry , vol.1
    • Sugawara, H.1    Iwamoto, K.2    Bundo, M.3    Ueda, J.4    Miyauchi, T.5
  • 50
    • 80053493397 scopus 로고    scopus 로고
    • Large-scale methylation domains mark a functional subset of neuronally expressed genes
    • Schroeder DI, Lott P, Korf I, Laselle JM, (2011) Large-scale methylation domains mark a functional subset of neuronally expressed genes. Genome Res 21: 1583-1591.
    • (2011) Genome Res , vol.21 , pp. 1583-1591
    • Schroeder, D.I.1    Lott, P.2    Korf, I.3    Laselle, J.M.4
  • 51
    • 25444486426 scopus 로고    scopus 로고
    • Gene expression levels assessed by oligonucleotide microarray analysis and quantitative real-time RT-PCR - how well do they correlate?
    • Dallas PB, Gottardo NG, Firth MJ, Beesley AH, Hoffmann K, et al. (2005) Gene expression levels assessed by oligonucleotide microarray analysis and quantitative real-time RT-PCR - how well do they correlate? BMC Genomics 6: 59.
    • (2005) BMC Genomics , vol.6 , pp. 59
    • Dallas, P.B.1    Gottardo, N.G.2    Firth, M.J.3    Beesley, A.H.4    Hoffmann, K.5
  • 52
    • 77957333258 scopus 로고    scopus 로고
    • Induction of epigenetic alterations by dietary and other environmental factors
    • Mathers JC, Strathdee G, Relton CL, (2010) Induction of epigenetic alterations by dietary and other environmental factors. Adv Genet 71: 3-39.
    • (2010) Adv Genet , vol.71 , pp. 3-39
    • Mathers, J.C.1    Strathdee, G.2    Relton, C.L.3


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