Sustained CD28 expression delays multiple features of replicative senescence in human CD8 T lymphocytes

Journal of Clinical Immunology

Volumn 30, Issue 6, 2010, Pages 798-805

  Parish, Stanley T ^a   Wu, Jennifer E ^a   Effros, Rita B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CD28; CTLA 4; Human; Replicative senescence; T lymphocytes; Telomerase

Indexed keywords

CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 6; TELOMERASE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CELL AGING; CELL DIVISION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; FUNCTIONAL MORPHOLOGY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SENESCENCE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

AGING; ANIMALS; ANTIGENS, CD28; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; DISEASE PROGRESSION; GENE EXPRESSION REGULATION; HIV INFECTIONS; HUMANS; SIGNAL TRANSDUCTION;

EID: 78651272579     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-010-9449-7     Document Type: Article

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