메뉴 건너뛰기




Volumn 17, Issue 12, 2011, Pages

N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI)

Author keywords

Alzheimer's disease (AD); Mild cognitive impairment (MCI)

Indexed keywords

CHOLINE; GLUTAMIC ACID; GLUTAMINE; INOSITOL; N ACETYLASPARTIC ACID;

EID: 82755186407     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.882112     Document Type: Article
Times cited : (26)

References (37)
  • 1
    • 0035195760 scopus 로고    scopus 로고
    • Current concepts in mild cognitive impairment
    • Petersen RG, Doody R, Kurz A et al: Current concepts in mild cognitive impairment. Arch Neurol, 2001; 58: 1985-92
    • (2001) Arch Neurol , vol.58 , pp. 1985-1992
    • Petersen, R.G.1    Doody, R.2    Kurz, A.3
  • 4
    • 54049096773 scopus 로고    scopus 로고
    • Prediction of deterioration of mild cognitive impairment with CT and SPECT
    • Gabryelewicz T, Pawlowska-Detko A, Misko J et al: Prediction of deterioration of mild cognitive impairment with CT and SPECT. Med Sci Monit, 2007; 13(Suppl.1): 31-37
    • (2007) Med Sci Monit , vol.13 , Issue.SUPPL. 1 , pp. 31-37
    • Gabryelewicz, T.1    Pawlowska-Detko, A.2    Misko, J.3
  • 5
    • 16844365618 scopus 로고    scopus 로고
    • Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain MR spectroscopy
    • Modrego PJ, Fayed N, Pina MA: Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain MR spectroscopy. Am J Psychiatry, 2005; 162: 667-75
    • (2005) Am J Psychiatry , vol.162 , pp. 667-675
    • Modrego, P.J.1    Fayed, N.2    Pina, M.A.3
  • 6
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer's disease
    • Braak H, Braak E: Neuropathological staging of Alzheimer's disease. Acta Neuropathol (Berl), 1991; 82: 239-59
    • (1991) Acta Neuropathol (Berl) , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 7
    • 0036942144 scopus 로고    scopus 로고
    • Structural cerebral changes in subjects with mild cognitive impairment
    • Pantel J, Huger Dr, Kratz B et al: Structural cerebral changes in subjects with mild cognitive impairment. Nervenarzt, 2002; 73: 845-50
    • (2002) Nervenarzt , vol.73 , pp. 845-850
    • Pantel, J.1    Huger, D.2    Kratz, B.3
  • 8
    • 0037330921 scopus 로고    scopus 로고
    • Early diagnosis of Alzheimer's disease: Contribution of structural neuroimaging
    • Chetelat G, Baron JC: Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging. Neuroimage, 2003; 18: 525-41
    • (2003) Neuroimage , vol.18 , pp. 525-541
    • Chetelat, G.1    Baron, J.C.2
  • 9
    • 0343416812 scopus 로고    scopus 로고
    • Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease
    • Jack CR, Petersen RC, Xu Y et al: Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology, 1997; 49: 786-94
    • (1997) Neurology , vol.49 , pp. 786-794
    • Jack, C.R.1    Petersen, R.C.2    Xu, Y.3
  • 10
    • 0035131830 scopus 로고    scopus 로고
    • Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment
    • Kordower JH, Chu Y, Stebbins GT et al: Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Ann Neurol, 2001; 49: 202-13
    • (2001) Ann Neurol , vol.49 , pp. 202-213
    • Kordower, J.H.1    Chu, Y.2    Stebbins, G.T.3
  • 11
    • 0034801730 scopus 로고    scopus 로고
    • Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
    • Du AT, Schuff N, Amend D et al: Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry, 2001; 71: 441-47
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 441-447
    • Du, A.T.1    Schuff, N.2    Amend, D.3
  • 12
    • 77954649156 scopus 로고    scopus 로고
    • Correlation of CT perfusion and CT volumetry in patients with AD
    • Czarnecka A, Zimny A, Sa{ogonek}siadek M: Correlation of CT perfusion and CT volumetry in patients with AD. Pol J Radiol, 2010: 75: 15-21
    • (2010) Pol J Radiol , vol.75 , pp. 15-21
    • Czarnecka, A.1    Zimny, A.2    Sasiadek, M.3
  • 13
    • 34047202247 scopus 로고    scopus 로고
    • Hippocampal and entorhinal atrophy in mild cognitive impairment: Prediction of Alzheimer disease
    • Devanand DP, Pradhaban G, Liu X et al: Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology, 2007; 68: 828-36
    • (2007) Neurology , vol.68 , pp. 828-836
    • Devanand, D.P.1    Pradhaban, G.2    Liu, X.3
  • 14
    • 0030982674 scopus 로고    scopus 로고
    • Age related cognitive decline: A clinical entity? A longitudinal study of cerebral blood flow and memory performance
    • Celsis P, Agneil A, Cardebrat D: Age related cognitive decline: a clinical entity? A longitudinal study of cerebral blood flow and memory performance. J Neurol Neurosurg Psychiatry, 1997; 62: 601-8
    • (1997) J Neurol Neurosurg Psychiatry , vol.62 , pp. 601-608
    • Celsis, P.1    Agneil, A.2    Cardebrat, D.3
  • 15
    • 0032952814 scopus 로고    scopus 로고
    • Neuropsychological function and cerebral glucose utilization in isolated memory impairment and Alzheimer's disease
    • Berent S, Giordani B, Foster N: Neuropsychological function and cerebral glucose utilization in isolated memory impairment and Alzheimer's disease. J Psychiatr Res, 1999; 33: 7-16
    • (1999) J Psychiatr Res , vol.33 , pp. 7-16
    • Berent, S.1    Giordani, B.2    Foster, N.3
  • 16
    • 0025991464 scopus 로고
    • The trouble with spectroscopy papers
    • Bottomley PA: The trouble with spectroscopy papers. Radiology, 1991; 181: 344-50
    • (1991) Radiology , vol.181 , pp. 344-350
    • Bottomley, P.A.1
  • 17
    • 0031454126 scopus 로고    scopus 로고
    • Changes of hippocampal N-acetyl aspartate and volume in Alzheimer's disease. A proton MR spectroscopic imaging and MRI study
    • Schuff N, Amend D, Ezekiel F et al: Changes of hippocampal N-acetyl aspartate and volume in Alzheimer's disease. A proton MR spectroscopic imaging and MRI study. Neurology, 1997; 49: 1513-21
    • (1997) Neurology , vol.49 , pp. 1513-1521
    • Schuff, N.1    Amend, D.2    Ezekiel, F.3
  • 18
    • 0036091568 scopus 로고    scopus 로고
    • Regional N-acetylaspartate reduction in the hippocampus detected with fast proton magnetic resonance spectroscopic imaging in patients with Alzheimer's disease
    • Block W, Jessen F et al: Regional N-acetylaspartate reduction in the hippocampus detected with fast proton magnetic resonance spectroscopic imaging in patients with Alzheimer's disease. Arch Neurol, 2002; 59: 828-34
    • (2002) Arch Neurol , vol.59 , pp. 828-834
    • Block, W.1    Jessen, F.2
  • 19
    • 0035828157 scopus 로고    scopus 로고
    • 1H-MR spectroscopy differentiates mild cognitive impairment from normal brain aging
    • Catani M, Cherubini A, Howard R et al: 1H-MR spectroscopy differentiates mild cognitive impairment from normal brain aging. Neuroreport, 2001; 12: 2315-17
    • (2001) Neuroreport , vol.12 , pp. 2315-2317
    • Catani, M.1    Cherubini, A.2    Howard, R.3
  • 20
    • 0033852551 scopus 로고    scopus 로고
    • Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS study
    • Kantarci K, Jack CR, Xu YC et al: Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: a 1H MRS study. Neurology, 2000; 55: 210-17
    • (2000) Neurology , vol.55 , pp. 210-217
    • Kantarci, K.1    Jack, C.R.2    Xu, Y.C.3
  • 21
    • 0036827038 scopus 로고    scopus 로고
    • 1H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease
    • Kantarci K, Smith GE, Ivnik RJ et al: 1H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease. J International Neuropsychological Society, 2002; 8: 934-42
    • (2002) J International Neuropsychological Society , vol.8 , pp. 934-942
    • Kantarci, K.1    Smith, G.E.2    Ivnik, R.J.3
  • 22
    • 0032550737 scopus 로고    scopus 로고
    • Metabolic brain mapping in Alzheimer's disease using proton magnetic resonance spectroscopy
    • Lazeyras F, Charles HC, Tupler LA et al: Metabolic brain mapping in Alzheimer's disease using proton magnetic resonance spectroscopy. Psychiatry Res, 1998; 82: 95-106
    • (1998) Psychiatry Res , vol.82 , pp. 95-106
    • Lazeyras, F.1    Charles, H.C.2    Tupler, L.A.3
  • 23
    • 0034643639 scopus 로고    scopus 로고
    • Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease
    • Adalsteinsson E, Sullivan EV, Kleinhans N et al: Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease. Lancet, 2000; 355(9216): 1696-97
    • (2000) Lancet , vol.355 , Issue.9216 , pp. 1696-1697
    • Adalsteinsson, E.1    Sullivan, E.V.2    Kleinhans, N.3
  • 24
    • 0038517131 scopus 로고    scopus 로고
    • Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: Comparison of 1.5 and 3T
    • Kantarci K, Reynolds G, Petersen RC et al: Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3T. Am J Neuroradiol, 2003; 24: 843-49
    • (2003) Am J Neuroradiol , vol.24 , pp. 843-849
    • Kantarci, K.1    Reynolds, G.2    Petersen, R.C.3
  • 25
  • 26
    • 80054020574 scopus 로고    scopus 로고
    • 1H-MRS in mild cognitive impairment (MCI)-the role of particular metabolites in prediction of MCI conversion to AD
    • 1H-MRS in mild cognitive impairment (MCI)-the role of particular metabolites in prediction of MCI conversion to AD. Med Sci Monit, 2010; 16(Suppl.1): 11-18
    • (2010) Med Sci Monit , vol.16 , Issue.SUPPL. 1 , pp. 11-18
    • Walecki, J.1    Pawłowska, A.2    Gabryelewicz, T.3
  • 27
    • 78651259279 scopus 로고    scopus 로고
    • Spectroscopy in patients after surgical clipping and endovascular embolisation of intracranial aneurysms
    • Tarasow E, Kochanowicz J, Mariak Z, Walecki MR: Spectroscopy in patients after surgical clipping and endovascular embolisation of intracranial aneurysms. Pol J Radiol, 2010; 75(4): 25-30
    • (2010) Pol J Radiol , vol.75 , Issue.4 , pp. 25-30
    • Tarasow, E.1    Kochanowicz, J.2    Mariak, Z.3    Walecki, M.R.4
  • 28
    • 0032587972 scopus 로고    scopus 로고
    • A 1H MRS study of probably Alzheimer disease and normal aging: Implication for longitudinal monitoring of fementia progression
    • Rose SE, de Zubicaray GI, Wang D et al: A 1H MRS study of probably Alzheimer disease and normal aging: implication for longitudinal monitoring of fementia progression. Magn Reson Imaging, 1999; 17: 291-99
    • (1999) Magn Reson Imaging , vol.17 , pp. 291-299
    • Rose, S.E.1    de Zubicaray, G.I.2    Wang, D.3
  • 29
    • 1642336453 scopus 로고    scopus 로고
    • Cognitive impairement classification of 1h MRS
    • Martinez-Bisbal MC, Arana E et al: Cognitive impairement classification of 1h MRS. Eur J Neurol, 2004; 11: 187-93
    • (2004) Eur J Neurol , vol.11 , pp. 187-193
    • Martinez-Bisbal, M.C.1    Arana, E.2
  • 31
    • 0036156958 scopus 로고    scopus 로고
    • Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment
    • DeKosky ST, Ikonomovic MD, Styren SD et al: Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol, 2002; 51: 145-55
    • (2002) Ann Neurol , vol.51 , pp. 145-155
    • DeKosky, S.T.1    Ikonomovic, M.D.2    Styren, S.D.3
  • 32
    • 0033729119 scopus 로고    scopus 로고
    • Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: A model of the membrane defect of Alzheimer's disease
    • Farber SA, Slack BE, Blusztajn JK: Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease. FASEB J, 2000; 14: 2198-206
    • (2000) FASEB J , vol.14 , pp. 2198-2206
    • Farber, S.A.1    Slack, B.E.2    Blusztajn, J.K.3
  • 33
    • 0026513962 scopus 로고
    • Evidence for a membrane defect in Alzheimer disease brain
    • Nitsch RM, Blusztajn JK, Pittas AG et al: Evidence for a membrane defect in Alzheimer disease brain. Proc Natl Acad Sci, 1992; 89: 1671-75
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 1671-1675
    • Nitsch, R.M.1    Blusztajn, J.K.2    Pittas, A.G.3
  • 34
    • 0038517131 scopus 로고    scopus 로고
    • Proton MR spectroscopy in mild cognitive impairment and Alzheimer's disease: Comparison of 1,5 and 3 T
    • Kantarci K, Reynolds G, Petersen RC et al: Proton MR spectroscopy in mild cognitive impairment and Alzheimer's disease: comparison of 1,5 and 3 T. Am J Neuroradiol, 2003; 24: 843-49
    • (2003) Am J Neuroradiol , vol.24 , pp. 843-849
    • Kantarci, K.1    Reynolds, G.2    Petersen, R.C.3
  • 35
    • 3042770430 scopus 로고    scopus 로고
    • 1H-MRS evaluation of metabolism in Alzheimer's disease and vascular dementia
    • 1H-MRS evaluation of metabolism in Alzheimer's disease and vascular dementia. Neurol Res, 2004; 26: 488-95
    • (2004) Neurol Res , vol.26 , pp. 488-495
    • Jones, R.S.1    Waldman, A.D.2
  • 36
    • 70449490612 scopus 로고    scopus 로고
    • Metodyka badań 1H MRS pojedynczego voxela ludzkiego mózgu in vivo
    • [in Polish]
    • Pienia{ogonek}żek P, Sokół M, Walecki J et al: Metodyka badań 1H MRS pojedynczego voxela ludzkiego mózgu in vivo. Diagnostyka Obrazowa, 2002: 1: 13-19 [in Polish]
    • (2002) Diagnostyka Obrazowa , vol.1 , pp. 13-19
    • Pieniazek, P.1    Sokół, M.2    Walecki, J.3
  • 37
    • 0033366674 scopus 로고    scopus 로고
    • Proton MR spectroscopy in patients with complex partial seizures: Single-voxel spectroscopy versus chemical-shift imaging
    • Yuan-Yu H, Chen C et al: Proton MR spectroscopy in patients with complex partial seizures: single-voxel spectroscopy versus chemical-shift imaging. Am J Neuroradiol, 1999; 20: 643-51
    • (1999) Am J Neuroradiol , vol.20 , pp. 643-651
    • Yuan-Yu, H.1    Chen, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.