-
1
-
-
0014094282
-
The inhibitory effect of chloroquine on rat adipose tissue metabolism in vitro
-
F.L. Benoit The inhibitory effect of chloroquine on rat adipose tissue metabolism in vitro Metabolism 16 1967 557 561
-
(1967)
Metabolism
, vol.16
, pp. 557-561
-
-
Benoit, F.L.1
-
2
-
-
39549122799
-
Remodeling phenotype of human subcutaneous adipose tissue macrophages
-
V. Bourlier, A. Zakaroff-Girard, A. Miranville, S. De Barros, M. Maumus, C. Sengenes, J. Galitzky, M. Lafontan, F. Karpe, K.N. Frayn, and A. Bouloumié Remodeling phenotype of human subcutaneous adipose tissue macrophages Circulation 117 2008 806 815
-
(2008)
Circulation
, vol.117
, pp. 806-815
-
-
Bourlier, V.1
Zakaroff-Girard, A.2
Miranville, A.3
De Barros, S.4
Maumus, M.5
Sengenes, C.6
Galitzky, J.7
Lafontan, M.8
Karpe, F.9
Frayn, K.N.10
Bouloumié, A.11
-
3
-
-
80355133234
-
Macrophage-mediated inflammation in metabolic disease
-
A. Chawla, K.D. Nguyen, and Y.P. Goh Macrophage-mediated inflammation in metabolic disease Nat. Rev. Immunol. 11 2011 738 749
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.3
-
4
-
-
79953667762
-
Advances in osteoclast biology: Old findings and new insights from mouse models
-
J.R. Edwards, and G.R. Mundy Advances in osteoclast biology: old findings and new insights from mouse models Nat Rev Rheumatol 7 2011 235 243
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 235-243
-
-
Edwards, J.R.1
Mundy, G.R.2
-
5
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
M. Feuerer, L. Herrero, D. Cipolletta, A. Naaz, J. Wong, A. Nayer, J. Lee, A.B. Goldfine, C. Benoist, S. Shoelson, and D. Mathis Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters Nat. Med. 15 2009 930 939
-
(2009)
Nat. Med.
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
6
-
-
77953268611
-
Alternative activation of macrophages: Mechanism and functions
-
S. Gordon, and F.O. Martinez Alternative activation of macrophages: mechanism and functions Immunity 32 2010 593 604
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
7
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
W. Huang, B.T. Sherman, and R.A. Lempicki Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists Nucleic Acids Res. 37 2009 1 13
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 1-13
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
8
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
W. Huang, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat. Protoc. 4 2009 44 57
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
9
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
M. Komatsu, S. Waguri, T. Chiba, S. Murata, J. Iwata, I. Tanida, T. Ueno, M. Koike, Y. Uchiyama, E. Kominami, and K. Tanaka Loss of autophagy in the central nervous system causes neurodegeneration in mice Nature 441 2006 880 884
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
Tanaka, K.11
-
10
-
-
77957838795
-
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
-
A. Kosteli, E. Sugaru, G. Haemmerle, J.F. Martin, J. Lei, R. Zechner, and A.W. Ferrante Jr. Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue J. Clin. Invest. 120 2010 3466 3479
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3466-3479
-
-
Kosteli, A.1
Sugaru, E.2
Haemmerle, G.3
Martin, J.F.4
Lei, J.5
Zechner, R.6
Ferrante Jr., A.W.7
-
11
-
-
78649499036
-
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages
-
L. Lichtenstein, F. Mattijssen, N.J. de Wit, A. Georgiadi, G.J. Hooiveld, R. van der Meer, Y. He, L. Qi, A. Köster, and J.T. Tamsma Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages Cell Metab. 12 2010 580 592
-
(2010)
Cell Metab.
, vol.12
, pp. 580-592
-
-
Lichtenstein, L.1
Mattijssen, F.2
De Wit, N.J.3
Georgiadi, A.4
Hooiveld, G.J.5
Van Der Meer, R.6
He, Y.7
Qi, L.8
Köster, A.9
Tamsma, J.T.10
-
12
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
C.N. Lumeng, J.L. Bodzin, and A.R. Saltiel Obesity induces a phenotypic switch in adipose tissue macrophage polarization J. Clin. Invest. 117 2007 175 184
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
13
-
-
33847073149
-
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
-
C.N. Lumeng, S.M. Deyoung, J.L. Bodzin, and A.R. Saltiel Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity Diabetes 56 2007 16 23
-
(2007)
Diabetes
, vol.56
, pp. 16-23
-
-
Lumeng, C.N.1
Deyoung, S.M.2
Bodzin, J.L.3
Saltiel, A.R.4
-
14
-
-
58149347227
-
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
-
C.N. Lumeng, J.B. DelProposto, D.J. Westcott, and A.R. Saltiel Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes Diabetes 57 2008 3239 3246
-
(2008)
Diabetes
, vol.57
, pp. 3239-3246
-
-
Lumeng, C.N.1
Delproposto, J.B.2
Westcott, D.J.3
Saltiel, A.R.4
-
15
-
-
33750813483
-
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
-
F.O. Martinez, S. Gordon, M. Locati, and A. Mantovani Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression J. Immunol. 177 2006 7303 7311
-
(2006)
J. Immunol.
, vol.177
, pp. 7303-7311
-
-
Martinez, F.O.1
Gordon, S.2
Locati, M.3
Mantovani, A.4
-
16
-
-
82555186955
-
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
-
K.D. Nguyen, Y. Qiu, X. Cui, Y.P. Goh, J. Mwangi, T. David, L. Mukundan, F. Brombacher, R.M. Locksley, and A. Chawla Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis Nature 480 2011 104 108
-
(2011)
Nature
, vol.480
, pp. 104-108
-
-
Nguyen, K.D.1
Qiu, Y.2
Cui, X.3
Goh, Y.P.4
Mwangi, J.5
David, T.6
Mukundan, L.7
Brombacher, F.8
Locksley, R.M.9
Chawla, A.10
-
17
-
-
77951146612
-
C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
-
A.E. Obstfeld, E. Sugaru, M. Thearle, A.M. Francisco, C. Gayet, H.N. Ginsberg, E.V. Ables, and A.W. Ferrante Jr. C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis Diabetes 59 2010 916 925
-
(2010)
Diabetes
, vol.59
, pp. 916-925
-
-
Obstfeld, A.E.1
Sugaru, E.2
Thearle, M.3
Francisco, A.M.4
Gayet, C.5
Ginsberg, H.N.6
Ables, E.V.7
Ferrante Jr., A.W.8
-
18
-
-
84857985148
-
The cellular and signaling networks linking the immune system and metabolism in disease
-
O. Osborn, and J.M. Olefsky The cellular and signaling networks linking the immune system and metabolism in disease Nat. Med. 18 2012 363 374
-
(2012)
Nat. Med.
, vol.18
, pp. 363-374
-
-
Osborn, O.1
Olefsky, J.M.2
-
19
-
-
79958030075
-
Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase
-
M. Ouimet, V. Franklin, E. Mak, X. Liao, I. Tabas, and Y.L. Marcel Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase Cell Metab. 13 2011 655 667
-
(2011)
Cell Metab.
, vol.13
, pp. 655-667
-
-
Ouimet, M.1
Franklin, V.2
Mak, E.3
Liao, X.4
Tabas, I.5
Marcel, Y.L.6
-
20
-
-
63149088164
-
Trophic macrophages in development and disease
-
J.W. Pollard Trophic macrophages in development and disease Nat. Rev. Immunol. 9 2009 259 270
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
21
-
-
0025779639
-
Mode of action of chloroquine in patients with non-insulin-dependent diabetes mellitus
-
J.K. Powrie, G.D. Smith, F. Shojaee-Moradie, P.H. Sönksen, and R.H. Jones Mode of action of chloroquine in patients with non-insulin-dependent diabetes mellitus Am. J. Physiol. 260 1991 E897 E904
-
(1991)
Am. J. Physiol.
, vol.260
-
-
Powrie, J.K.1
Smith, G.D.2
Shojaee-Moradie, F.3
Sönksen, P.H.4
Jones, R.H.5
-
22
-
-
0027481309
-
Effects of chloroquine on the dyslipidemia of non-insulin-dependent diabetes mellitus
-
J.K. Powrie, F. Shojaee-Moradie, G.F. Watts, G.D. Smith, P.H. Sönksen, and R.H. Jones Effects of chloroquine on the dyslipidemia of non-insulin-dependent diabetes mellitus Metabolism 42 1993 415 419
-
(1993)
Metabolism
, vol.42
, pp. 415-419
-
-
Powrie, J.K.1
Shojaee-Moradie, F.2
Watts, G.F.3
Smith, G.D.4
Sönksen, P.H.5
Jones, R.H.6
-
23
-
-
69249227502
-
Lysosome biogenesis and lysosomal membrane proteins: Trafficking meets function
-
P. Saftig, and J. Klumperman Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function Nat. Rev. Mol. Cell Biol. 10 2009 623 635
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 623-635
-
-
Saftig, P.1
Klumperman, J.2
-
24
-
-
77951822653
-
Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet - Induced obesity in mice
-
M.E. Shaul, G. Bennett, K.J. Strissel, A.S. Greenberg, and M.S. Obin Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet - induced obesity in mice Diabetes 59 2010 1171 1181
-
(2010)
Diabetes
, vol.59
, pp. 1171-1181
-
-
Shaul, M.E.1
Bennett, G.2
Strissel, K.J.3
Greenberg, A.S.4
Obin, M.S.5
-
25
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
H. Shi, M.V. Kokoeva, K. Inouye, I. Tzameli, H. Yin, and J.S. Flier TLR4 links innate immunity and fatty acid-induced insulin resistance J. Clin. Invest. 116 2006 3015 3025
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
26
-
-
84859768059
-
Lipophagy: Connecting autophagy and lipid metabolism
-
R. Singh, and A.M. Cuervo Lipophagy: connecting autophagy and lipid metabolism Int. J. Cell Biol. 2012 2012 282041
-
(2012)
Int. J. Cell Biol.
, vol.2012
, pp. 282041
-
-
Singh, R.1
Cuervo, A.M.2
-
27
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
R. Singh, S. Kaushik, Y. Wang, Y. Xiang, I. Novak, M. Komatsu, K. Tanaka, A.M. Cuervo, and M.J. Czaja Autophagy regulates lipid metabolism Nature 458 2009 1131 1135
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.3
Xiang, Y.4
Novak, I.5
Komatsu, M.6
Tanaka, K.7
Cuervo, A.M.8
Czaja, M.J.9
-
28
-
-
70449448312
-
Autophagy regulates adipose mass and differentiation in mice
-
R. Singh, Y. Xiang, Y. Wang, K. Baikati, A.M. Cuervo, Y.K. Luu, Y. Tang, J.E. Pessin, G.J. Schwartz, and M.J. Czaja Autophagy regulates adipose mass and differentiation in mice J. Clin. Invest. 119 2009 3329 3339
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3329-3339
-
-
Singh, R.1
Xiang, Y.2
Wang, Y.3
Baikati, K.4
Cuervo, A.M.5
Luu, Y.K.6
Tang, Y.7
Pessin, J.E.8
Schwartz, G.J.9
Czaja, M.J.10
-
29
-
-
33846323706
-
Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages
-
T. Suganami, K. Tanimoto-Koyama, J. Nishida, M. Itoh, X. Yuan, S. Mizuarai, H. Kotani, S. Yamaoka, K. Miyake, and S. Aoe Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages Arterioscler. Thromb. Vasc. Biol. 27 2007 84 91
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 84-91
-
-
Suganami, T.1
Tanimoto-Koyama, K.2
Nishida, J.3
Itoh, M.4
Yuan, X.5
Mizuarai, S.6
Kotani, H.7
Yamaoka, S.8
Miyake, K.9
Aoe, S.10
-
30
-
-
84868671526
-
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
-
S. Talukdar, Y. Oh, G. Bandyopadhyay, D. Li, J. Xu, J. McNelis, M. Lu, P. Li, Q. Yan, and Y. Zhu Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase Nat. Med. 18 2012 1407 1412
-
(2012)
Nat. Med.
, vol.18
, pp. 1407-1412
-
-
Talukdar, S.1
Oh, Y.2
Bandyopadhyay, G.3
Li, D.4
Xu, J.5
McNelis, J.6
Lu, M.7
Li, P.8
Yan, Q.9
Zhu, Y.10
-
31
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
S.P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R.L. Leibel, and A.W. Ferrante Jr. Obesity is associated with macrophage accumulation in adipose tissue J. Clin. Invest. 112 2003 1796 1808
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
32
-
-
85027938385
-
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
-
D.A. Winer, S. Winer, L. Shen, P.P. Wadia, J. Yantha, G. Paltser, H. Tsui, P. Wu, M.G. Davidson, and M.N. Alonso B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies Nat. Med. 17 2011 610 617
-
(2011)
Nat. Med.
, vol.17
, pp. 610-617
-
-
Winer, D.A.1
Winer, S.2
Shen, L.3
Wadia, P.P.4
Yantha, J.5
Paltser, G.6
Tsui, H.7
Wu, P.8
Davidson, M.G.9
Alonso, M.N.10
-
33
-
-
33847280286
-
T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity
-
H. Wu, S. Ghosh, X.D. Perrard, L. Feng, G.E. Garcia, J.L. Perrard, J.F. Sweeney, L.E. Peterson, L. Chan, C.W. Smith, and C.M. Ballantyne T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesity Circulation 115 2007 1029 1038
-
(2007)
Circulation
, vol.115
, pp. 1029-1038
-
-
Wu, H.1
Ghosh, S.2
Perrard, X.D.3
Feng, L.4
Garcia, G.E.5
Perrard, J.L.6
Sweeney, J.F.7
Peterson, L.E.8
Chan, L.9
Smith, C.W.10
Ballantyne, C.M.11
-
34
-
-
79953815551
-
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
-
D. Wu, A.B. Molofsky, H.E. Liang, R.R. Ricardo-Gonzalez, H.A. Jouihan, J.K. Bando, A. Chawla, and R.M. Locksley Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis Science 332 2011 243 247
-
(2011)
Science
, vol.332
, pp. 243-247
-
-
Wu, D.1
Molofsky, A.B.2
Liang, H.E.3
Ricardo-Gonzalez, R.R.4
Jouihan, H.A.5
Bando, J.K.6
Chawla, A.7
Locksley, R.M.8
-
35
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
H. Xu, G.T. Barnes, Q. Yang, G. Tan, D. Yang, C.J. Chou, J. Sole, A. Nichols, J.S. Ross, L.A. Tartaglia, and H. Chen Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance J. Clin. Invest. 112 2003 1821 1830
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
36
-
-
73949124173
-
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
-
Y. Zhang, S. Goldman, R. Baerga, Y. Zhao, M. Komatsu, and S. Jin Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis Proc. Natl. Acad. Sci. USA 106 2009 19860 19865
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
Zhao, Y.4
Komatsu, M.5
Jin, S.6
|