메뉴 건너뛰기




Volumn 7, Issue SUPPL 5, 2013, Pages

Computational drug repositioning through heterogeneous network clustering

Author keywords

[No Author keywords available]

Indexed keywords

ANILIDE; PROTEINASE INHIBITOR; PYRIDINE DERIVATIVE; SECRETASE; VISMODEGIB;

EID: 84889655691     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-7-S5-S6     Document Type: Article
Times cited : (125)

References (51)
  • 1
    • 4344668661 scopus 로고    scopus 로고
    • Drug repositioning: identifying and developing new uses for existing drugs
    • 10.1038/nrd1468, 15286734
    • Ashburn TT, Thor KB. Drug repositioning: identifying and developing new uses for existing drugs. Nat Rev Drug Discov 2004, 3(8):673-683. 10.1038/nrd1468, 15286734.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.8 , pp. 673-683
    • Ashburn, T.T.1    Thor, K.B.2
  • 2
    • 67149130229 scopus 로고    scopus 로고
    • Drug discovery. Repurposing with a difference
    • Boguski MS, Mandl KD, Sukhatme VP. Drug discovery. Repurposing with a difference. Science New York, NY 2009, 324(5933):1394-1395.
    • (2009) Science New York, NY , vol.324 , Issue.5933 , pp. 1394-1395
    • Boguski, M.S.1    Mandl, K.D.2    Sukhatme, V.P.3
  • 3
    • 77649182705 scopus 로고    scopus 로고
    • Unveiling the role of network and systems biology in drug discovery
    • 10.1016/j.tips.2009.11.006, 20117850
    • Pujol A, Mosca R, Farres J, Aloy P. Unveiling the role of network and systems biology in drug discovery. Trends Pharmacol Sci 2010, 31(3):115-123. 10.1016/j.tips.2009.11.006, 20117850.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.3 , pp. 115-123
    • Pujol, A.1    Mosca, R.2    Farres, J.3    Aloy, P.4
  • 5
    • 84875459651 scopus 로고    scopus 로고
    • Computational drug repositioning: from data to therapeutics
    • 10.1038/clpt.2013.1, 23443757
    • Hurle MR, Yang L, Xie Q, Rajpal DK, Sanseau P, Agarwal P. Computational drug repositioning: from data to therapeutics. Clin Pharmacol Ther 2013, 93(4):335-341. 10.1038/clpt.2013.1, 23443757.
    • (2013) Clin Pharmacol Ther , vol.93 , Issue.4 , pp. 335-341
    • Hurle, M.R.1    Yang, L.2    Xie, Q.3    Rajpal, D.K.4    Sanseau, P.5    Agarwal, P.6
  • 7
    • 68449088145 scopus 로고    scopus 로고
    • Human Disease-Drug Network Based on Genomic Expression Profiles
    • 10.1371/journal.pone.0006536, 2715883, 19657382
    • Hu G, Agarwal P. Human Disease-Drug Network Based on Genomic Expression Profiles. PLoS ONE 2009, 4(8):e6536. 10.1371/journal.pone.0006536, 2715883, 19657382.
    • (2009) PLoS ONE , vol.4 , Issue.8
    • Hu, G.1    Agarwal, P.2
  • 8
    • 84867338003 scopus 로고    scopus 로고
    • Discovery and preclinical validation of drug indications using compendia of public gene expression data
    • 10.1126/scitranslmed.3001318, 3502016, 21849665
    • Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ. Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med 2011, 3(96):96ra77. 10.1126/scitranslmed.3001318, 3502016, 21849665.
    • (2011) Sci Transl Med , vol.3 , Issue.96
    • Sirota, M.1    Dudley, J.T.2    Kim, J.3    Chiang, A.P.4    Morgan, A.A.5    Sweet-Cordero, A.6    Sage, J.7    Butte, A.J.8
  • 12
    • 84871748184 scopus 로고    scopus 로고
    • DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data
    • 10.1093/bioinformatics/bts656, 3530913, 23129297
    • Pacini C, Iorio F, Goncalves E, Iskar M, Klabunde T, Bork P, Saez-Rodriguez J. DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data. Bioinformatics 2013, 29(1):132-134. 10.1093/bioinformatics/bts656, 3530913, 23129297.
    • (2013) Bioinformatics , vol.29 , Issue.1 , pp. 132-134
    • Pacini, C.1    Iorio, F.2    Goncalves, E.3    Iskar, M.4    Klabunde, T.5    Bork, P.6    Saez-Rodriguez, J.7
  • 13
    • 83755163958 scopus 로고    scopus 로고
    • Systematic Drug Repositioning Based on Clinical Side-Effects
    • 10.1371/journal.pone.0028025, 3244383, 22205936
    • Yang L, Agarwal P. Systematic Drug Repositioning Based on Clinical Side-Effects. PLoS ONE 2011, 6(12):e28025. 10.1371/journal.pone.0028025, 3244383, 22205936.
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Yang, L.1    Agarwal, P.2
  • 14
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • 10.1126/science.1158140, 18621671
    • Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P. Drug target identification using side-effect similarity. Science 2008, 321(5886):263-266. 10.1126/science.1158140, 18621671.
    • (2008) Science , vol.321 , Issue.5886 , pp. 263-266
    • Campillos, M.1    Kuhn, M.2    Gavin, A.C.3    Jensen, L.J.4    Bork, P.5
  • 15
    • 84856055845 scopus 로고    scopus 로고
    • Recycling side-effects into clinical markers for drug repositioning
    • 10.1186/gm302, 3334551, 22283977
    • Duran-Frigola M, Aloy P. Recycling side-effects into clinical markers for drug repositioning. Genome Med 2012, 4(1):3. 10.1186/gm302, 3334551, 22283977.
    • (2012) Genome Med , vol.4 , Issue.1 , pp. 3
    • Duran-Frigola, M.1    Aloy, P.2
  • 16
    • 70350227039 scopus 로고    scopus 로고
    • Systematic evaluation of drug-disease relationships to identify leads for novel drug uses
    • 10.1038/clpt.2009.103, 2836384, 19571805
    • Chiang AP, Butte AJ. Systematic evaluation of drug-disease relationships to identify leads for novel drug uses. Clinical pharmacology and therapeutics 2009, 86(5):507-510. 10.1038/clpt.2009.103, 2836384, 19571805.
    • (2009) Clinical pharmacology and therapeutics , vol.86 , Issue.5 , pp. 507-510
    • Chiang, A.P.1    Butte, A.J.2
  • 17
    • 84863695210 scopus 로고    scopus 로고
    • Prediction of drug-target interactions and drug repositioning via network-based inference
    • 10.1371/journal.pcbi.1002503, 3349722, 22589709
    • Cheng F, Liu C, Jiang J, Lu W, Li W, Liu G, Zhou W, Huang J, Tang Y. Prediction of drug-target interactions and drug repositioning via network-based inference. PLoS Comput Biol 2012, 8(5):e1002503. 10.1371/journal.pcbi.1002503, 3349722, 22589709.
    • (2012) PLoS Comput Biol , vol.8 , Issue.5
    • Cheng, F.1    Liu, C.2    Jiang, J.3    Lu, W.4    Li, W.5    Liu, G.6    Zhou, W.7    Huang, J.8    Tang, Y.9
  • 18
    • 84889685618 scopus 로고    scopus 로고
    • A two-step drug repositioning method based on a protein-protein interaction network of genes shared by two diseases and the similarity of drugs
    • 10.6026/97320630009089, 3563404, 23390352
    • Yutaka Fukuoka DT, Hisamichi O. A two-step drug repositioning method based on a protein-protein interaction network of genes shared by two diseases and the similarity of drugs. Bioinformation 2013, 9(2):89-93. 10.6026/97320630009089, 3563404, 23390352.
    • (2013) Bioinformation , vol.9 , Issue.2 , pp. 89-93
    • Yutaka Fukuoka, D.T.1    Hisamichi, O.2
  • 19
    • 79958754253 scopus 로고    scopus 로고
    • PREDICT: a method for inferring novel drug indications with application to personalized medicine
    • Assaf G, Gideon YS, Eytan R, Roded S. PREDICT: a method for inferring novel drug indications with application to personalized medicine. Molecular Systems Biology 2011, 7(1).
    • (2011) Molecular Systems Biology , vol.7 , Issue.1
    • Assaf, G.1    Gideon, Y.S.2    Eytan, R.3    Roded, S.4
  • 23
    • 79960796417 scopus 로고    scopus 로고
    • Exploiting drug-disease relationships for computational drug repositioning
    • 10.1093/bib/bbr013, 3137933, 21690101
    • Dudley JT, Deshpande T, Butte AJ. Exploiting drug-disease relationships for computational drug repositioning. Briefings in Bioinformatics 2011, 12(4):303-311. 10.1093/bib/bbr013, 3137933, 21690101.
    • (2011) Briefings in Bioinformatics , vol.12 , Issue.4 , pp. 303-311
    • Dudley, J.T.1    Deshpande, T.2    Butte, A.J.3
  • 24
    • 77649222972 scopus 로고    scopus 로고
    • Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets
    • 10.1371/journal.pcbi.1000662, 2816673, 20140234
    • Suthram S, Dudley JT, Chiang AP, Chen R, Hastie TJ, Butte AJ. Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets. PLoS Comput Biol 2010, 6(2):e1000662. 10.1371/journal.pcbi.1000662, 2816673, 20140234.
    • (2010) PLoS Comput Biol , vol.6 , Issue.2
    • Suthram, S.1    Dudley, J.T.2    Chiang, A.P.3    Chen, R.4    Hastie, T.J.5    Butte, A.J.6
  • 26
    • 84860361165 scopus 로고    scopus 로고
    • Detecting overlapping protein complexes in protein-protein interaction networks
    • Nepusz T, Yu H, Paccanaro A. Detecting overlapping protein complexes in protein-protein interaction networks. Nat Meth 2012, 9(5):471-472.
    • (2012) Nat Meth , vol.9 , Issue.5 , pp. 471-472
    • Nepusz, T.1    Yu, H.2    Paccanaro, A.3
  • 27
    • 75549090213 scopus 로고    scopus 로고
    • KEGG for representation and analysis of molecular networks involving diseases and drugs
    • 2808910, 19880382
    • Kanehisa M, Goto S, Furumichi M, Tanabe M, Hirakawa M. KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Research 2010, 38(suppl 1):D355-D360. 2808910, 19880382.
    • (2010) Nucleic Acids Research , vol.38 , Issue.SUPPL. 1
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3    Tanabe, M.4    Hirakawa, M.5
  • 29
    • 67849130563 scopus 로고    scopus 로고
    • ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
    • 2703978, 19465376
    • Chen J, Bardes EE, Aronow BJ, Jegga AG. ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Research 2009, 37(suppl 2):W305-W311. 2703978, 19465376.
    • (2009) Nucleic Acids Research , vol.37 , Issue.SUPPL. 2
    • Chen, J.1    Bardes, E.E.2    Aronow, B.J.3    Jegga, A.G.4
  • 31
    • 84874354420 scopus 로고    scopus 로고
    • A survey of computational methods for protein complex prediction from protein interaction networks
    • 10.1142/S021972001230002X, 23600810
    • Srihari S, Leong HW. A survey of computational methods for protein complex prediction from protein interaction networks. Journal of Bioinformatics and Computational Biology 2013, 11(2):1230002. 10.1142/S021972001230002X, 23600810.
    • (2013) Journal of Bioinformatics and Computational Biology , vol.11 , Issue.2 , pp. 1230002
    • Srihari, S.1    Leong, H.W.2
  • 32
    • 84876760070 scopus 로고    scopus 로고
    • The Potential of Text Mining in Data Integration and Network Biology for Plant Research: A Case Study on Arabidopsis
    • Van Landeghem S, De Bodt S, Drebert ZJ, Inzé D, Van de Peer Y. The Potential of Text Mining in Data Integration and Network Biology for Plant Research: A Case Study on Arabidopsis. The Plant Cell Online 2013,
    • (2013) The Plant Cell Online
    • Van Landeghem, S.1    De Bodt, S.2    Drebert, Z.J.3    Inzé, D.4    Van de Peer, Y.5
  • 33
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
    • 10.1101/gr.1239303, 403769, 14597658
    • Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T. Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks. Genome Research 2003, 13(11):2498-2504. 10.1101/gr.1239303, 403769, 14597658.
    • (2003) Genome Research , vol.13 , Issue.11 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.S.4    Wang, J.T.5    Ramage, D.6    Amin, N.7    Schwikowski, B.8    Ideker, T.9
  • 34
    • 78651317908 scopus 로고    scopus 로고
    • Entrez Gene: gene-centered information at NCBI
    • 3013746, 21115458
    • Maglott D, Ostell J, Pruitt KD, Tatusova T. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Research 2011, 39(suppl 1):D52-D57. 3013746, 21115458.
    • (2011) Nucleic Acids Research , vol.39 , Issue.SUPPL. 1
    • Maglott, D.1    Ostell, J.2    Pruitt, K.D.3    Tatusova, T.4
  • 37
    • 79958811512 scopus 로고    scopus 로고
    • The orphan disease networks
    • 10.1016/j.ajhg.2011.05.006, 3113244, 21664998
    • Zhang M, Zhu C, Jacomy A, Lu LJ, Jegga AG. The orphan disease networks. Am J Hum Genet 2011, 88(6):755-766. 10.1016/j.ajhg.2011.05.006, 3113244, 21664998.
    • (2011) Am J Hum Genet , vol.88 , Issue.6 , pp. 755-766
    • Zhang, M.1    Zhu, C.2    Jacomy, A.3    Lu, L.J.4    Jegga, A.G.5
  • 44
    • 0036826903 scopus 로고    scopus 로고
    • Selective inhibition of Abeta42 production by NSAID R-enantiomers
    • 10.1046/j.1471-4159.2002.01195.x, 12421374
    • Morihara T, Chu T, Ubeda O, Beech W, Cole GM. Selective inhibition of Abeta42 production by NSAID R-enantiomers. J Neurochem 2002, 83(4):1009-1012. 10.1046/j.1471-4159.2002.01195.x, 12421374.
    • (2002) J Neurochem , vol.83 , Issue.4 , pp. 1009-1012
    • Morihara, T.1    Chu, T.2    Ubeda, O.3    Beech, W.4    Cole, G.M.5
  • 46
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • 10.1126/science.1072994, 12130773
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297(5580):353-356. 10.1126/science.1072994, 12130773.
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 47
    • 0026597063 scopus 로고
    • Alzheimer's disease: the amyloid cascade hypothesis
    • 10.1126/science.1566067, 1566067
    • Hardy JA, Higgins GA. Alzheimer's disease: the amyloid cascade hypothesis. Science 1992, 256(5054):184-185. 10.1126/science.1566067, 1566067.
    • (1992) Science , vol.256 , Issue.5054 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 48
    • 0025753852 scopus 로고
    • The molecular pathology of Alzheimer's disease
    • 10.1016/0896-6273(91)90052-2, 1673054
    • Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991, 6(4):487-498. 10.1016/0896-6273(91)90052-2, 1673054.
    • (1991) Neuron , vol.6 , Issue.4 , pp. 487-498
    • Selkoe, D.J.1
  • 49
    • 78449272415 scopus 로고    scopus 로고
    • Genetics. Gamma-secretase and human disease
    • 10.1126/science.1198668, 21097925
    • Kelleher RJ, Shen J. Genetics. Gamma-secretase and human disease. Science 2010, 330(6007):1055-1056. 10.1126/science.1198668, 21097925.
    • (2010) Science , vol.330 , Issue.6007 , pp. 1055-1056
    • Kelleher, R.J.1    Shen, J.2
  • 51
    • 84876888105 scopus 로고    scopus 로고
    • Challenges and opportunities of drug repositioning
    • Novac N. Challenges and opportunities of drug repositioning. Trends Pharmacol Sci 2013,
    • (2013) Trends Pharmacol Sci
    • Novac, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.