-
1
-
-
0347928864
-
Rocaglamide derivatives are potent inhibitors of NF-κB activation in T-cells
-
DOI 10.1074/jbc.M208003200
-
Baumann B, Bohnenstengel F, Siegmund D et al. Rocaglamide derivatives are potent inhibitors of NF-kB activation in T-cells. J. Biol. Chem. 277(47), 44791-44800 (2002). (Pubitemid 36159073)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 44791-44800
-
-
Baumann, B.1
Bohnenstengel, F.2
Siegmund, D.3
Wajant, H.4
Weber, C.5
Herr, I.6
Debatin, K.-M.7
Proksch, P.8
Wirth, T.9
-
2
-
-
0020422866
-
X-ray crystal structure of rocaglamide, a novel antileukemic 1H-cyclopenta[b]benzofuran from Aglaia elliptifolia
-
King ML, Chiang CC, Ling HC, Fujita E, Ochiai M, McPhail AT. x-ray crystal structure of rocaglamide, a novel antileukemic 1H-cyclopenta[b] benzofuran from Aglaia elliptifolia. Chem. Commun. 20(1982), 1150-1151 (1992).
-
(1992)
Chem. Commun
, vol.20
, Issue.1982
, pp. 1150-1151
-
-
King, M.L.1
Chiang, C.C.2
Ling, H.C.3
Fujita, E.4
Ochiai, M.5
McPhail, A.T.6
-
3
-
-
82255176981
-
Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from Aglaia species (Meliaceae
-
Ebada SS, Lajkiewicz N, Porco JA Jr, Li- Weber M, Proksch P. Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from Aglaia species (Meliaceae). Prog. Chem. Org. Nat. Prod. 94, 1-58 (2011).
-
(2011)
Prog. Chem. Org. Nat. Prod.
, vol.94
, pp. 1-58
-
-
Ebada, S.S.1
Lajkiewicz, N.2
Porco Jr., J.A.3
Li- Weber, M.4
Proksch, P.5
-
4
-
-
84857919771
-
Recent advances in the biology and chemistry of the flavaglines
-
Ribeiro N, Thuaud F, Nebigil C, Dsaubry L. Recent advances in the biology and chemistry of the flavaglines. Bioorg. Med. Chem. 20(6), 1857-1864 (2012).
-
(2012)
Bioorg. Med. Chem.
, vol.20
, Issue.6
, pp. 1857-1864
-
-
Ribeiro, N.1
Thuaud, F.2
Nebigil, C.3
Dsaubry, L.4
-
5
-
-
84870479106
-
Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor
-
Lindqvist LM, Vikstrom I, Chambers JM et al. Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor. Cell. Death. Dis. 3, e409 (2012).
-
(2012)
Cell. Death. Dis
, vol.3
-
-
Lindqvist, L.M.1
Vikstrom, I.2
Chambers, J.M.3
-
6
-
-
18944393390
-
Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells
-
Proksch P, Giaisi M, Treiber MK et al. Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells. J. Immunol, 174(11), 7075-7084 (2005). (Pubitemid 40705673)
-
(2005)
Journal of Immunology
, vol.174
, Issue.11
, pp. 7075-7084
-
-
Proksch, P.1
Giaisi, M.2
Treiber, M.K.3
Palfi, K.4
Merling, A.5
Spring, H.6
Krammer, P.H.7
Li-Weber, M.8
-
7
-
-
69049104101
-
Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression
-
Zhu JY, Giaisi M, Kohler R et al. Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression. Cell Death Differ. 16(9), 1289-1299 (2009).
-
(2009)
Cell Death Differ.
, vol.16
, Issue.9
, pp. 1289-1299
-
-
Zhu, J.Y.1
Giaisi, M.2
Kohler, R.3
-
8
-
-
34548676362
-
The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities
-
DOI 10.1002/ijc.22883
-
Zhu JY, Lavrik IN, Mahlknecht U et al. The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities. Int. J. Cancer 121(8), 1839-1846 (2007). (Pubitemid 47417305)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.8
, pp. 1839-1846
-
-
Zhu, J.Y.1
Lavrik, I.N.2
Mahlknecht, U.3
Giaisi, M.4
Proksch, P.5
Krammer, P.H.6
Li-Weber, M.7
-
9
-
-
33745851542
-
Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy
-
Kim S, Salim AA, Swanson SM, Kinghorn AD. Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy. Anticancer. Agents Med. Chem. 6(4), 319-345 (2006). (Pubitemid 44027699)
-
(2006)
Anti-Cancer Agents in Medicinal Chemistry
, vol.6
, Issue.4
, pp. 319-345
-
-
Kim, S.1
Salim, A.A.2
Swanson, S.M.3
Kinghorn, A.D.4
-
10
-
-
0035174453
-
Chemistry and biological activity of rocaglamide derivatives and related compounds in Aglaia species (Meliaceae)
-
DOI 10.2174/1385272013375049
-
Proksch P, Edrada R, Ebel R, Bohnenstengel F, Nugroho B. Chemistry and biological activity of rocaglamide derivatives and related compounds in Aglaia species (Meliaceae). Curr. Org. Chem. 5, 923-938 (2001). (Pubitemid 33069422)
-
(2001)
Current Organic Chemistry
, vol.5
, Issue.9
, pp. 923-938
-
-
Proksch, P.1
-
11
-
-
0025606444
-
An unusual oxidative cyclization. A synthesis and absolute stereochemical assignment of (-)-rocoglamide
-
Trost BM, Greenspan PD, Yang BV, Saulnier MG. An unusual oxidative cyclization. A synthesis and absolute stereochemical assignment of (-)-rocoglamide. J. Am. Chem. Soc. 112(24), 9022-9024 (1990).
-
(1990)
J. Am. Chem. Soc.
, vol.112
, Issue.24
, pp. 9022-9024
-
-
Trost, B.M.1
Greenspan, P.D.2
Yang, B.V.3
Saulnier, M.G.4
-
12
-
-
84857206865
-
Total synthesis of ()-rocaglamide via oxidation-initiated nazarov cyclization
-
Malona JA, Cariou K, Spencer WT III, Frontier AJ. Total synthesis of ()-rocaglamide via oxidation-initiated nazarov cyclization. J. Org. Chem. 77(4), 1891-1908 (2012).
-
(2012)
J. Org. Chem.
, vol.77
, Issue.4
, pp. 1891-1908
-
-
Malona, J.A.1
Cariou, K.2
Spencer III, W.T.3
Frontier, A.J.4
-
13
-
-
84859570038
-
Formal synthesis of ()-methyl rocaglate using an unprecedented acetyl bromide mediated nazarov reaction
-
Magnus P, Freund WA, Moorhead EJ, Rainey T. Formal synthesis of ()-methyl rocaglate using an unprecedented acetyl bromide mediated nazarov reaction. J. Am. Chem. Soc. 134(14), 6140-6142 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, Issue.14
, pp. 6140-6142
-
-
Magnus, P.1
Freund, W.A.2
Moorhead, E.J.3
Rainey, T.4
-
14
-
-
84864675937
-
Enantioselective photocycloaddition of 3-hydroxyflavones: Total syntheses and absolute configuration assignments of (+)-ponapensin and (+)-elliptifoline
-
Lajkiewicz NJ, Roche SP, Gerard B, Porco JA. Enantioselective photocycloaddition of 3-hydroxyflavones: total syntheses and absolute configuration assignments of (+)-ponapensin and (+)-elliptifoline. J. Am. Chem. Soc. 134(31), 13108-13113 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, Issue.31
, pp. 13108-13113
-
-
Lajkiewicz, N.J.1
Roche, S.P.2
Gerard, B.3
Porco, J.A.4
-
15
-
-
84867760869
-
Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors
-
Liu T, Nair SJ, Lescarbeau A et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J. Med. Chem. 55(20), 8859-8878 (2012).
-
(2012)
J. Med. Chem.
, vol.55
, Issue.20
, pp. 8859-8878
-
-
Liu, T.1
Nair, S.J.2
Lescarbeau, A.3
-
16
-
-
84866661335
-
The natural anticancer compounds rocaglamides inhibit the RAF-MEK-ERK pathway by targeting prohibitin 1 and 2
-
Polier G, Neumann J, Thuaud F et al. The natural anticancer compounds rocaglamides inhibit the RAF-MEK-ERK pathway by targeting prohibitin 1 and 2. Chem. Biol. 19(9), 1093-1104 (2012).
-
(2012)
Chem. Biol
, vol.19
, Issue.9
, pp. 1093-1104
-
-
Polier, G.1
Neumann, J.2
Thuaud, F.3
-
17
-
-
84875439224
-
Prohibitin ligands in cell death and survival: Mode of action and therapeutic potential
-
Thuaud F, Ribeiro N, Nebigil CG, Dsaubry L. Prohibitin ligands in cell death and survival: mode of action and therapeutic potential. Chem. Biol. 20(3), 316-331 (2013).
-
(2013)
Chem. Biol
, vol.20
, Issue.3
, pp. 316-331
-
-
Thuaud, F.1
Ribeiro, N.2
Nebigil, C.G.3
Dsaubry, L.4
-
18
-
-
79960064432
-
RAF family kinases: Old dogs have learned new tricks
-
Matallanas D, Birtwistle M, Romano D et al. RAF family kinases: old dogs have learned new tricks. Genes Cancer 2(3), 232-260 (2011).
-
(2011)
Genes Cancer
, vol.2
, Issue.3
, pp. 232-260
-
-
Matallanas, D.1
Birtwistle, M.2
Romano, D.3
-
19
-
-
46749097944
-
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model
-
DOI 10.1172/JC134753
-
Bordeleau ME, Robert F, Gerard B et al. Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model. J. Clin. Invest. 118(7), 2651-2660 (2008). (Pubitemid 351949792)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.7
, pp. 2651-2660
-
-
Bordeleau, M.-E.1
Robert, F.2
Gerard, B.3
Lindqvist, L.4
Chen, S.M.H.5
Wendel, H.-G.6
Brem, B.7
Greger, H.8
Lowe, S.W.9
Porco Jr., J.A.10
Pelletier, J.11
-
20
-
-
65549098672
-
Antitumor activity and mechanism of action of the cyclopenta[b] benzofuran, silvestrol
-
Cencic R, Carrier M, Galicia-Vazquez G et al. Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. PLoS ONE 4(4), e5223 (2009).
-
(2009)
PLoS ONE
, vol.4
, Issue.4
-
-
Cencic, R.1
Carrier, M.2
Galicia-Vazquez, G.3
-
21
-
-
84874106479
-
EIF4F suppression in breast cancer affects maintenance and progression
-
Nasr Z, Robert F, Porco JA Jr., Muller WJ, Pelletier J. eIF4F suppression in breast cancer affects maintenance and progression. Oncogene 32(7), 861-871 (2012).
-
(2012)
Oncogene
, vol.32
, Issue.7
, pp. 861-871
-
-
Nasr, Z.1
Robert, F.2
Porco Jr., J.A.3
Muller, W.J.4
Pelletier, J.5
-
22
-
-
80054845323
-
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
-
Schatz JH, Oricchio E, Wolfe AL et al. Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma. J. Exp. Med. 208(9), 1799-1807 (2011).
-
(2011)
J. Exp. Med
, vol.208
, Issue.9
, pp. 1799-1807
-
-
Schatz, J.H.1
Oricchio, E.2
Wolfe, A.L.3
-
23
-
-
84870037639
-
Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein
-
Jin C, Rajabi H, Rodrigo CM, Porco JA Jr., Kufe D. Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein. Oncogene 32(17), 2179-2188 (2012).
-
(2012)
Oncogene
, vol.32
, Issue.17
, pp. 2179-2188
-
-
Jin, C.1
Rajabi, H.2
Rodrigo, C.M.3
Porco Jr., J.A.4
Kufe, D.5
-
24
-
-
84865788129
-
Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol
-
Alinari L, Prince CJ, Edwards RB et al. Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol. Clin. Cancer Res. 18(17), 4600-4611 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, Issue.17
, pp. 4600-4611
-
-
Alinari, L.1
Prince, C.J.2
Edwards, R.B.3
-
25
-
-
62149149441
-
The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo
-
Lucas DM, Edwards RB, Lozanski G et al. The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo. Blood 113(19), 4656-4666 (2009).
-
(2009)
Blood
, vol.113
, Issue.19
, pp. 4656-4666
-
-
Lucas, D.M.1
Edwards, R.B.2
Lozanski, G.3
-
26
-
-
84875158511
-
Synthesis of biotinylated Episilvestrol: Highly selective targeting of the translation factors eIF4AI/II
-
Chambers JM, Lindqvist LM, Webb A, Huang DCS, Savage GP, Rizzacasa MA. Synthesis of biotinylated Episilvestrol: highly selective targeting of the translation factors eIF4AI/II. Org. Lett. 15(6), 1406-1409 (2013).
-
(2013)
Org. Lett.
, vol.15
, Issue.6
, pp. 1406-1409
-
-
Chambers, J.M.1
Lindqvist, L.M.2
Webb, A.3
Dcs, H.4
Savage, G.P.5
Rizzacasa, M.A.6
-
27
-
-
84880532125
-
Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA Complex
-
Sadlish H, Galicia-Vazquez G, Paris CG et al. Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA Complex. ACS Chem. Biol. 8 (7), 1519-1527 (2013).
-
(2013)
ACS Chem. Biol.
, vol.8
, Issue.7
, pp. 1519-1527
-
-
Sadlish, H.1
Galicia-Vazquez, G.2
Paris, C.G.3
-
28
-
-
84880438841
-
Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state
-
Santagata S, Mendillo ML, Tang YC et al. Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state. Science 341(6143), 1238303 (2013).
-
(2013)
Science
, vol.341
, Issue.6143
, pp. 1238303
-
-
Santagata, S.1
Mendillo, M.L.2
Tang, Y.C.3
-
29
-
-
84866425291
-
Translational control in cancer etiology
-
Ruggero D. Translational control in cancer etiology. Cold Spring Harb. Perspect. Biol. 5(2) (2013).
-
(2013)
Cold Spring Harb. Perspect. Biol
, vol.5
, Issue.2
-
-
Ruggero, D.1
-
30
-
-
84875197785
-
Prohibitin and its rapidly emerging role as a biomarker of systemic malignancies-reply
-
Guo F, Hiroshima K, Wu D et al. Prohibitin and its rapidly emerging role as a biomarker of systemic malignancies-reply. Hum. Pathol. 44(4), 679-680 (2013).
-
(2013)
Hum. Pathol.
, vol.44
, Issue.4
, pp. 679-680
-
-
Guo, F.1
Hiroshima, K.2
Wu, D.3
-
31
-
-
84875128199
-
Prohibitin and its rapidly emerging role as a biomarker of systemic malignancies
-
Kapoor S. Prohibitin and its rapidly emerging role as a biomarker of systemic malignancies. Hum. Pathol. 44(4), 678-679 (2013).
-
(2013)
Hum. Pathol
, vol.44
, Issue.4
, pp. 678-679
-
-
Kapoor, S.1
-
32
-
-
81055146759
-
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys
-
Barnhart KF, Christianson DR, Hanley PW et al. A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys. Sci. Transl. Med. 3(108), 108ra112 (2011).
-
(2011)
Sci. Transl. Med
, vol.3
, Issue.108
, pp. 108-112
-
-
Barnhart, K.F.1
Christianson, D.R.2
Hanley, P.W.3
-
33
-
-
33645832379
-
Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells
-
Mi Q, Su BN, Chai H et al. Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells. Anticancer Res. 26(2A), 947-952 (2006).
-
(2006)
Anticancer Res
, vol.26
, Issue.2
, pp. 947-952
-
-
Mi, Q.1
Su, B.N.2
Chai, H.3
-
34
-
-
69049117290
-
Synthetic analogue of Rocaglaol displays a potent and selective cytotoxicity in cancer cells: Involvement of apoptosis inducing factor and Caspase-12
-
Thuaud F, Bernard Y, Turkeri G et al. Synthetic analogue of Rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and Caspase-12. J. Med Chem, 52(16), 5176-5187 (2009).
-
(2009)
J. Med Chem
, vol.52
, Issue.16
, pp. 5176-5187
-
-
Thuaud, F.1
Bernard, Y.2
Turkeri, G.3
-
35
-
-
0032476106
-
Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica
-
DOI 10.1016/S0009-2797(98)00073-8, PII S0009279798000738
-
Lee SK, Cui B, Mehta RR, Kinghorn AD, Pezzuto JM. Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica. Chem. Biol. Interact. 115(3), 215-228 (1998). (Pubitemid 28487025)
-
(1998)
Chemico-Biological Interactions
, vol.115
, Issue.3
, pp. 215-228
-
-
Lee, S.K.1
Cui, B.2
Mehta, R.R.3
Kinghorn, A.D.4
Pezzuto, J.M.5
-
36
-
-
67651216410
-
Next generation oncology drug development: Opportunities and challenges
-
Gutierrez ME, Kummar S, Giaccone G. Next generation oncology drug development: opportunities and challenges. Nat. Rev. Clin. Oncol. 6(5), 259-265 (2009).
-
(2009)
Nat. Rev. Clin. Oncol
, vol.6
, Issue.5
, pp. 259-265
-
-
Gutierrez, M.E.1
Kummar, S.2
Giaccone, G.3
-
37
-
-
84855855153
-
Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: Synthetic and biological studies
-
Rodrigo CM, Cencic R, Roche SP, Pelletier J, Porco JA. Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies. J. Med. Chem., 55(1), 558-562 (2012).
-
(2012)
J. Med. Chem
, vol.55
, Issue.1
, pp. 558-562
-
-
Rodrigo, C.M.1
Cencic, R.2
Roche, S.P.3
Pelletier, J.4
Porco, J.A.5
-
38
-
-
84867760869
-
Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors
-
Liu T, Nair SJ, Lescarbeau A et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J. Med. Chem. 55(20), 8859-8878 (2012).
-
(2012)
J. Med. Chem
, vol.55
, Issue.20
, pp. 8859-8878
-
-
Liu, T.1
Nair, S.J.2
Lescarbeau, A.3
-
39
-
-
2442561376
-
Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives from Aglaia silvestris
-
DOI 10.1021/jo040120f
-
Hwang BY, Su BN, Chai H et al. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J. Org. Chem. 69(10), 3350-3358 (2004). (Pubitemid 38621283)
-
(2004)
Journal of Organic Chemistry
, vol.69
, Issue.10
, pp. 3350-3358
-
-
Hwang, B.Y.1
Su, B.-N.2
Chai, H.3
Mi, Q.4
Kardono, L.B.S.5
Afriastini, J.J.6
Riswan, S.7
Santarsiero, B.D.8
Mesecar, A.D.9
Wild, R.10
Fairchild, C.R.11
Vite, G.D.12
Rose, W.C.13
Farnsworth, N.R.14
Cordell, G.A.15
Pezzuto, J.M.16
Swanson, S.M.17
Kinghorn, A.D.18
-
40
-
-
84874930771
-
Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia
-
Alachkar H, Santhanam R, Harb JG et al. Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia. J. Hematol. Oncol. 6, 21 (2013).
-
(2013)
J. Hematol. Oncol
, vol.6
, Issue.21
-
-
Alachkar, H.1
Santhanam, R.2
Harb, J.G.3
-
41
-
-
80052575249
-
Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells
-
Gupta SV, Sass EJ, Davis ME et al. Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells. AAPS J. 13(3), 357-364 (2011).
-
(2011)
AAPS J.
, vol.13
, Issue.3
, pp. 357-364
-
-
Gupta, S.V.1
Sass, E.J.2
Davis, M.E.3
-
42
-
-
78651083992
-
Novel flavaglines displaying improved cytotoxicity
-
Thuaud F, Ribeiro N, Gaiddon C, Cresteil T, Dsaubry L. Novel flavaglines displaying improved cytotoxicity. J. Med. Chem. 54, 411-415 (2011).
-
(2011)
J. Med. Chem
, vol.54
, pp. 411-415
-
-
Thuaud, F.1
Ribeiro, N.2
Gaiddon, C.3
Cresteil, T.4
Dsaubry, L.5
-
43
-
-
84870044595
-
Flavaglines as potent anticancer and cytoprotective agents
-
Ribeiro N, Thuaud F, Bernard Y et al. Flavaglines as potent anticancer and cytoprotective agents. J. Med. Chem. 55, 10064-10073 (2012).
-
(2012)
J. Med. Chem
, vol.55
, pp. 10064-10073
-
-
Ribeiro, N.1
Thuaud, F.2
Bernard, Y.3
-
44
-
-
17844403724
-
A synthetic derivative of the natural product rocaglaol is a potent inhibitor of cytokine-mediated signaling and shows neuroprotective activity in vitro and in animal models of Parkinson's disease and traumatic brain injury
-
DOI 10.1124/mol.104.008177
-
Fahrig T, Gerlach I, Horvath E. A synthetic derivative of the natural product rocaglaol is a potent inhibitor of cytokine-mediated signaling and shows neuroprotective activity in vitro and in animal models of Parkinson's disease and traumatic brain injury. Mol. Pharmacol. 67(5), 1544-1555 (2005). (Pubitemid 40594153)
-
(2005)
Molecular Pharmacology
, vol.67
, Issue.5
, pp. 1544-1555
-
-
Fahrig, T.1
Gerlach, I.2
Horvath, E.3
-
45
-
-
84872187489
-
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes
-
Lucas CR, Cordero-Nieves HM, Erbe RS et al. Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes. J. Immunol. 190(2), 723-736 (2013).
-
(2013)
J. Immunol.
, vol.190
, Issue.2
, pp. 723-736
-
-
Lucas, C.R.1
Cordero-Nieves, H.M.2
Erbe, R.S.3
-
46
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologie developments in antitumor activity and cardiotoxicity
-
DOI 10.1124/pr.56.2.6
-
Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev. 56(2), 185-229 (2004). (Pubitemid 38720829)
-
(2004)
Pharmacological Reviews
, vol.56
, Issue.2
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
47
-
-
80055110679
-
Flavaglines alleviate doxorubicin cardiotoxicity: Implication of Hsp27
-
Bernard Y, Ribeiro N, Thuaud F et al. Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27. PLoS ONE 6, e25302 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Bernard, Y.1
Ribeiro, N.2
Thuaud, F.3
-
48
-
-
70350474677
-
Heat shock protein 27 phosphorylation: Kinases, phosphatases, functions and pathology
-
Kostenko S, Moens U. Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology. Cell. Mol. Life Sci. 66, 3289-3307 (2009).
-
(2009)
Cell. Mol. Life Sci
, vol.66
, pp. 3289-3307
-
-
Kostenko, S.1
Moens, U.2
-
49
-
-
0347481379
-
Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling
-
DOI 10.1074/jbc.M305171200
-
Fusaro G, Dasgupta P, Rastogi S, Joshi B, Chellappan S. Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling. J. Biol. Chem. 278(48), 47853-47861 (2003). (Pubitemid 37523233)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.48
, pp. 47853-47861
-
-
Fusaro, G.1
Dasgupta, P.2
Rastogi, S.3
Joshi, B.4
Chellappan, S.5
-
50
-
-
84863330883
-
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice
-
Di Marco S, Cammas A, Lian XJ et al. The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice. Nat. Commun. 3, 896 (2012).
-
(2012)
Nat. Commun
, vol.3
, Issue.896
-
-
Di Marco, S.1
Cammas, A.2
Lian, X.J.3
-
51
-
-
77953422876
-
Inhibitors of translation initiation as cancer therapeutics
-
Lindqvist L, Pelletier J. Inhibitors of translation initiation as cancer therapeutics. Future Med. Chem. 1(9), 1709-1722 (2009).
-
(2009)
Future Med. Chem
, vol.1
, Issue.9
, pp. 1709-1722
-
-
Lindqvist, L.1
Pelletier, J.2
-
52
-
-
4344700840
-
Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine A: Design, synthesis, and activity studies leading to a potent simplified derivative
-
DOI 10.1021/ja040065s
-
Romo D, Choi NS, Li S, Buchler I, Shi Z, Liu JO. Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative. J. Am. Chem. Soc. 126(34), 10582-10588 (2004). (Pubitemid 39129157)
-
(2004)
Journal of the American Chemical Society
, vol.126
, Issue.34
, pp. 10582-10588
-
-
Romo, D.1
Choi, N.S.2
Li, S.3
Buchler, I.4
Shi, Z.5
Liu, J.O.6
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