Next generation oncology drug development: Opportunities and challenges

Nature Reviews Clinical Oncology

Volumn 6, Issue 5, 2009, Pages 259-265

  Gutierrez, Martin E ^a   Kummar, Shivaani ^a   Giaccone, Giuseppe ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; BEVACIZUMAB; CARBOXYAMINOIMIDAZOLE; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROURACIL; FOLINIC ACID; GEFITINIB; IMATINIB; PLACEBO; SORAFENIB; SUNITINIB; UNCLASSIFIED DRUG;

BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; COLORECTAL CANCER; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG MEGADOSE; DRUG POTENTIATION; DRUG SAFETY; GASTROINTESTINAL STROMAL TUMOR; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; KIDNEY CANCER; KIDNEY CARCINOMA; LOW DRUG DOSE; LUNG NON SMALL CELL CANCER; MALIGNANT NEOPLASTIC DISEASE; MAXIMUM TOLERATED DOSE; MELANOMA; OVARY CANCER; OVERALL SURVIVAL; PRIORITY JOURNAL; REVIEW; SURVIVAL TIME; DRUG DESIGN; DRUG SCREENING; METHODOLOGY; NEOPLASM; ONCOLOGY; PATIENT SELECTION;

ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAXIMUM TOLERATED DOSE; MEDICAL ONCOLOGY; NEOPLASMS; PATIENT SELECTION; RESEARCH DESIGN;

EID: 67651216410     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2009.38     Document Type: Review

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