-
1
-
-
0032811313
-
The role of mass spectrometry in thedrug discovery process
-
B. N. Pramanik, P. L. Bartner, and G. Chen, The role of mass spectrometry in thedrug discovery process, Curr. Opin. Drug Discovery Dev. 2 (1999), 401-417.
-
(1999)
Curr. Opin. Drug Discovery Dev.
, vol.2
, pp. 401-417
-
-
Pramanik, B.N.1
Bartner, P.L.2
Chen, G.3
-
2
-
-
1842527063
-
LC/MS Applications in Drug Development
-
John Wiley & Sons, New York
-
M. S. Lee, LC/MS Applications in Drug Development, John Wiley & Sons, New York, 2002.
-
(2002)
-
-
Lee, M.S.1
-
3
-
-
0000939952
-
Mass spectrometers
-
in G. L.Trigg (ed) VCH Publishers, New York
-
R. G. Cooks, G. Chen, and P.Wong, Mass spectrometers, in G. L.Trigg (ed), Encyclopediaof Applied Physics, VCH Publishers, New York, 1997, pp. 289-330.
-
(1997)
Encyclopediaof Applied Physics
, pp. 289-330
-
-
Cooks, R.G.1
Chen, G.2
Wong, P.3
-
4
-
-
33947334687
-
Chemical ionization mass spectrometry. I. Generalintroduction
-
M.S.B. Munson and F. H.Field, Chemical ionization mass spectrometry. I. Generalintroduction, J. Am. Chem. Soc. 88 (1966), 2621-2630.
-
(1966)
J. Am. Chem. Soc.
, vol.88
, pp. 2621-2630
-
-
Munson, M.S.B.1
Field, F.H.2
-
5
-
-
0019955082
-
Mass spectrometry of large, fragile, and involatilemolecules, Science
-
Washington, DC, United States
-
K. L. Busch and R. G. Cooks, Mass spectrometry of large, fragile, and involatilemolecules, Science (Washington, DC, United States) 218 (1982), 247-254.
-
(1982)
, vol.218
, pp. 247-254
-
-
Busch, K.L.1
Cooks, R.G.2
-
6
-
-
0019779528
-
Fast atombombardment mass spectrometry of bleomycin A2 and B2 and their metalcomplexes
-
M. Barber, R. S. Bordoli, R. D. Sedgwick, A. N.Tyler, and B.V. Bycroft, Fast atombombardment mass spectrometry of bleomycin A2 and B2 and their metalcomplexes, Biochemi. Biophysi. Res. Communi. 101 (1981), 632-638.
-
(1981)
Biochemi. Biophysi. Res. Communi.
, vol.101
, pp. 632-638
-
-
Barber, M.1
Bordoli, R.S.2
Sedgwick, R.D.3
Tyler, A.N.4
Bycroft, B.V.5
-
7
-
-
0003776074
-
Secondary Ion MassSpectrometry: Basic Concepts, Instrumental Aspects
-
John Wiley & Sons, New York
-
A. Benninghoven, H. W. Werner, and F. G. Rudenauer, Secondary Ion MassSpectrometry: Basic Concepts, Instrumental Aspects, Applications and Trends, John Wiley & Sons, New York, 1986.
-
(1986)
Applications and Trends
-
-
Benninghoven, A.1
Werner, H.W.2
Rudenauer, F.G.3
-
8
-
-
0017240393
-
Californium-252 plasma desorption massspectroscopy
-
R. D. Macfarlane and D. F. Torgerson, Californium-252 plasma desorption massspectroscopy, Science 191 (1976), 920-925.
-
(1976)
Science
, vol.191
, pp. 920-925
-
-
Macfarlane, R.D.1
Torgerson, D.F.2
-
9
-
-
24644477568
-
Matrix-assisted ultravioletlaser desorption of non-volatile compounds
-
Ion Processes
-
M. Karas, D. Bachmann, U. Bahr, and F. Hillenkamp, Matrix-assisted ultravioletlaser desorption of non-volatile compounds, Int. J. Mass Spectrom. Ion Processes78 (1987), 53-68.
-
(1987)
Int. J. Mass Spectrom.
, vol.78
, pp. 53-68
-
-
Karas, M.1
Bachmann, D.2
Bahr, U.3
Hillenkamp, F.4
-
10
-
-
5644249240
-
Mass spectrometry samplingunder ambient conditions with desorption electrospray ionization
-
Z. Takats, J. M.Wiseman, B. Gologan, and R. G. Cooks, Mass spectrometry samplingunder ambient conditions with desorption electrospray ionization, Science306 (2004), 471-473.
-
(2004)
Science
, vol.306
, pp. 471-473
-
-
Takats, Z.1
Wiseman, J.M.2
Gologan, B.3
Cooks, R.G.4
-
11
-
-
84889333469
-
Capillary systemfor introducing liquid mixtures into an analytical mass spectrometer
-
V. L. Tal'roze, G. V. Karpov, I. G. Gorodetskii, and V. E. Skurat, Capillary systemfor introducing liquid mixtures into an analytical mass spectrometer, Z. Fizi.Khim. 42 (1968), 3104-3112.338
-
(1968)
Z. Fizi.Khim.
, vol.42
-
-
Tal'roze, V.L.1
Karpov, G.V.2
Gorodetskii, I.G.3
Skurat, V.E.4
-
12
-
-
1542644568
-
Liquid chromatography/massspectrometry system providing continuous monitoring with nanogram sensitivity
-
P. J. Arpino, B. G. Dawkins, and F. W. McLafferty, Liquid chromatography/massspectrometry system providing continuous monitoring with nanogram sensitivity, J. Chromatogr. Sci. 12 (1974), 574-578.
-
(1974)
J. Chromatogr. Sci.
, vol.12
, pp. 574-578
-
-
Arpino, P.J.1
Dawkins, B.G.2
McLafferty, F.W.3
-
13
-
-
0000931493
-
Direct analysis of liquid chromatographiceffluents
-
W. H. McFadden, H. L. Schwartz, and S. Evans, Direct analysis of liquid chromatographiceffluents, J. Chromatogr. 122 (1974), 389-396.
-
(1974)
J. Chromatogr.
, vol.122
, pp. 389-396
-
-
McFadden, W.H.1
Schwartz, H.L.2
Evans, S.3
-
14
-
-
33845551548
-
Thermospray interface for liquid chromatography/mass spectrometry
-
C. R. Blakley and M. L. Vestal, Thermospray interface for liquid chromatography/mass spectrometry, Anal. Chem. 55 (1983), 750-754.
-
(1983)
Anal. Chem.
, vol.55
, pp. 750-754
-
-
Blakley, C.R.1
Vestal, M.L.2
-
15
-
-
0023020792
-
A continuous-flow sample probe for fastatom bombardment mass spectrometry
-
R. M. Caprioli, T. Fan, and J. S. Cottrell, A continuous-flow sample probe for fastatom bombardment mass spectrometry, Anal. Chem. 58 (1986), 2949-2954.
-
(1986)
Anal. Chem.
, vol.58
, pp. 2949-2954
-
-
Caprioli, R.M.1
Fan, T.2
Cottrell, J.S.3
-
16
-
-
0000867286
-
Direct coupling of micro highperformanceliquid chromatography with fast atom bombardment massspectrometry
-
Y. Ito, T. Takeuchi, D. Ishii, and M. Goto, Direct coupling of micro highperformanceliquid chromatography with fast atom bombardment massspectrometry, J. Chromatogr. 346 (1985), 161-166.
-
(1985)
J. Chromatogr.
, vol.346
, pp. 161-166
-
-
Ito, Y.1
Takeuchi, T.2
Ishii, D.3
Goto, M.4
-
17
-
-
33846598444
-
Instability of electrified liquid surfaces
-
J. Zeleny, Instability of electrified liquid surfaces, Phys. Rev. 10 (1917), 1-6.
-
(1917)
Phys. Rev.
, vol.10
, pp. 1-6
-
-
Zeleny, J.1
-
18
-
-
36849098646
-
Molecular beams of macroions
-
L. L. Mack, P. Kralik, A. Rheude, and M. Dole, Molecular beams of macroions. II.J. Chem. Phys. 52 (1970), 4977-4986.
-
(1970)
II.J. Chem. Phys.
, vol.52
, pp. 4977-4986
-
-
Mack, L.L.1
Kralik, P.2
Rheude, A.3
Dole, M.4
-
19
-
-
26844503278
-
Molecular beams of macroions
-
M. Dole, L. L. Mack, R. L. Hines, R. C. Mobley, L. D. Ferguson, and M. B. Alice, Molecular beams of macroions, J. Chem. Phys. 49 (1968), 2240-2249.
-
(1968)
J. Chem. Phys.
, vol.49
, pp. 2240-2249
-
-
Dole, M.1
Mack, L.L.2
Hines, R.L.3
Mobley, R.C.4
Ferguson, L.D.5
Alice, M.B.6
-
20
-
-
19844379850
-
Atmospheric pressure ionevaporation-mass spectrometry
-
J. V. Iribarne, P. J. Dziedzic, and B. A. Thomson, Atmospheric pressure ionevaporation-mass spectrometry, Int. J. Mass Spectrom. Ion Phys. 50 (1983),331-347.
-
(1983)
Int. J. Mass Spectrom. Ion Phys.
, vol.50
, pp. 331-347
-
-
Iribarne, J.V.1
Dziedzic, P.J.2
Thomson, B.A.3
-
21
-
-
26844505533
-
Field-induced ion evaporation from liquid surfacesat atmospheric pressure
-
B. A. Thomson and J. V. Iribarne, Field-induced ion evaporation from liquid surfacesat atmospheric pressure, J. Chem. Phys. 71 (1979), 4451-4463.
-
(1979)
J. Chem. Phys.
, vol.71
, pp. 4451-4463
-
-
Thomson, B.A.1
Iribarne, J.V.2
-
22
-
-
33748168091
-
Electrospray ion source. Another variation on thefree-jet theme
-
M. Yamashita and J. B. Fenn, Electrospray ion source. Another variation on thefree-jet theme, J. Phys. Chem. 88 (1984), 4451-4459.
-
(1984)
J. Phys. Chem.
, vol.88
, pp. 4451-4459
-
-
Yamashita, M.1
Fenn, J.B.2
-
23
-
-
0001681723
-
Ion extraction from solutions at atmospheric pressure-a methodfor mass-spectrometric analysis of bioorganic substances
-
Dokl.Akad. Nauk SSSR
-
M. L. Aleksandrov, L. N. Gall, N. V. Krasnov, V. I. Nikolaev, V. A. Pavlenko, andV. A. Shkurov, Ion extraction from solutions at atmospheric pressure-a methodfor mass-spectrometric analysis of bioorganic substances, Dokl.Akad. Nauk SSSR277 (1984), 379-383.
-
(1984)
, vol.277
, pp. 379-383
-
-
Aleksandrov, M.L.1
Gall, L.N.2
Krasnov, N.V.3
Nikolaev, V.I.4
Pavlenko, V.A.5
Shkurov, andV.A.6
-
24
-
-
0003791448
-
Applied Electrospray Mass Spectrometry
-
Marcel Dekker, New York
-
B. N. Pramanik, A. K. Ganguly, and M. L. Gross, Applied Electrospray Mass Spectrometry, Marcel Dekker, New York, 2002.
-
(2002)
-
-
Pramanik, B.N.1
Ganguly, A.K.2
Gross, M.L.3
-
25
-
-
0033926938
-
A brief overview of the present status of the mechanisms involved inelectrospray mass spectrometry
-
J. Mass Spectrom
-
P. Kebarle, A brief overview of the present status of the mechanisms involved inelectrospray mass spectrometry, J. Mass Spectrom. 35 (2000), 804-817.
-
(2000)
, vol.35
, pp. 804-817
-
-
Kebarle, P.1
-
26
-
-
0024438708
-
Electrosprayionization for mass spectrometry of large biomolecules
-
J. B. Fenn, M. Mann, C. K. Meng, S. F.Wong, and C. M.Whitehouse, Electrosprayionization for mass spectrometry of large biomolecules, Science 246 (1989), 64-71.
-
(1989)
Science
, vol.246
, pp. 64-71
-
-
Fenn, J.B.1
Mann, M.2
Meng, C.K.3
Wong, S.F.4
Whitehouse, C.M.5
-
27
-
-
0025424768
-
New developmentsin biochemical mass spectrometry: Electrospray ionization
-
R.D. Smith, J.A. Loo, C.G. Edmonds, C. J. Barinaga, and H. R. Udseth, New developmentsin biochemical mass spectrometry: Electrospray ionization, Anal. Chem.62 (1990), 882-899.
-
(1990)
Anal. Chem.
, vol.62
, pp. 882-899
-
-
Smith, R.D.1
Loo, J.A.2
Edmonds, C.G.3
Barinaga, C.J.4
Udseth, H.R.5
-
28
-
-
33947086174
-
Newpicogram detection system based on a mass spectrometer with an externalionization source at atmospheric pressure
-
E. C. Horning, M. G. Horning, D. I. Carroll, I. Dzidic, and R. N. Stillwell, Newpicogram detection system based on a mass spectrometer with an externalionization source at atmospheric pressure, Anal. Chem. 45 (1973), 936-943.
-
(1973)
Anal. Chem.
, vol.45
, pp. 936-943
-
-
Horning, E.C.1
Horning, M.G.2
Carroll, D.I.3
Dzidic, I.4
Stillwell, R.N.5
-
29
-
-
0021650968
-
Monodisperse aerosol generation interfacefor combining liquid chromatography with mass spectroscopy
-
R. C.Willoughby and R. F. Browner, Monodisperse aerosol generation interfacefor combining liquid chromatography with mass spectroscopy, Anal. Chem. 56(1984), 2625-2631.
-
(1984)
Anal. Chem.
, vol.56
, pp. 2625-2631
-
-
Willoughby, R.C.1
Browner, R.F.2
-
30
-
-
0034254295
-
Atmospheric pressure photoionization:An ionization method for liquid chromatography-mass spectrometry
-
D. B. Robb, T. R. Covey, and A. P. Bruins, Atmospheric pressure photoionization:An ionization method for liquid chromatography-mass spectrometry, Anal.Chem. 72 (2000), 3653-3659. 339
-
(2000)
Anal.Chem.
, vol.72
-
-
Robb, D.B.1
Covey, T.R.2
Bruins, A.P.3
-
31
-
-
84889370719
-
Isotopes
-
Edward Arnold & Co., London, UK
-
F.W. Aston, Isotopes, Edward Arnold & Co., London, UK.
-
-
-
Aston, F.W.1
-
32
-
-
0003843122
-
Quadrupole Mass Spectrometry and its Applications
-
Elsevier, Amsterdam, The Netherlands
-
P. H. Dawson (ed.), Quadrupole Mass Spectrometry and its Applications, Elsevier, Amsterdam, The Netherlands, 1976.
-
(1976)
-
-
Dawson, P.H.1
-
33
-
-
0038559342
-
Quadrupole mass filters and quadrupole Iontraps
-
in R. M. Caprioli, A. Malorni, and G. Sindona (eds.), Series C, Kluwer AcademicPublishers, Dordrecht,
-
R. G. Cooks, G. Chen, and C.Weil, Quadrupole mass filters and quadrupole Iontraps, in R. M. Caprioli, A. Malorni, and G. Sindona (eds.), Selected Topics in MassSpectrometry in the Biomolecular Sciences, Series C, Vol. 504 Kluwer AcademicPublishers, Dordrecht, 1997, pp. 213-238.
-
(1997)
Selected Topics in MassSpectrometry in the Biomolecular Sciences
, vol.504
, pp. 213-238
-
-
Cooks, R.G.1
Chen, G.2
Weil, C.3
-
34
-
-
0001325675
-
A two-dimensional quadrupole iontrap mass spectrometer
-
J. C. Schwartz, M.W. Senko, and J. E. P. Syka, A two-dimensional quadrupole iontrap mass spectrometer, J. Am. Soc. Mass Spectrom. 13 (2002), 659-669.
-
(2002)
J. Am. Soc. Mass Spectrom.
, vol.13
, pp. 659-669
-
-
Schwartz, J.C.1
Senko, M.W.2
Syka, J.E.P.3
-
35
-
-
0028876390
-
Principles and instrumentation in time-of-flight mass spectrometry.Physical and instrumental concepts
-
J. Mass Spectrom
-
M. Guilhaus, Principles and instrumentation in time-of-flight mass spectrometry.Physical and instrumental concepts, J. Mass Spectrom. 30 (1995), 1519-1532.
-
(1995)
, vol.30
, pp. 1519-1532
-
-
Guilhaus, M.1
-
36
-
-
0002757475
-
Mass reflectron.New nonmagnetic time-of-flight high-resolution mass spectrometer
-
B. A. Mamyrin, V. I. Karataev, D. V. Shmikk, and V. A. Zagulin, Mass reflectron.New nonmagnetic time-of-flight high-resolution mass spectrometer, Z. Eksp.Teoreticheskoi Fiz. 64 (1973), 82-89.
-
(1973)
Z. Eksp.Teoreticheskoi Fiz.
, vol.64
, pp. 82-89
-
-
Mamyrin, B.A.1
Karataev, V.I.2
Shmikk, D.V.3
Zagulin, V.A.4
-
37
-
-
0002922762
-
The production of high speed light ionswithout the use of high voltages
-
E. O. Lawrence and M. S. Livingston, The production of high speed light ionswithout the use of high voltages, Phys. Rev. 40 (1932), 19-35.
-
(1932)
Phys. Rev.
, vol.40
, pp. 19-35
-
-
Lawrence, E.O.1
Livingston, M.S.2
-
38
-
-
0001268221
-
Fourier transform ion cyclotron resonancespectroscopy
-
M. B. Comisarow and A. G. Marshall, Fourier transform ion cyclotron resonancespectroscopy, Chem. Phys. Lett. 25 (1974), 282-283.
-
(1974)
Chem. Phys. Lett.
, vol.25
, pp. 282-283
-
-
Comisarow, M.B.1
Marshall, A.G.2
-
39
-
-
0019882891
-
Tandem mass spectrometry
-
F.W. McLafferty, Tandem mass spectrometry, Science 214 (1981), 280-287.
-
(1981)
Science
, vol.214
, pp. 280-287
-
-
McLafferty, F.W.1
-
40
-
-
0001341506
-
Collision-induced decompositions of aromatic molecular ions
-
K. R. Jennings, Collision-induced decompositions of aromatic molecular ions, Int.J. Mass Spectrom. Ion Phys. 1 (1968), 227-235.
-
(1968)
Int.J. Mass Spectrom. Ion Phys.
, vol.1
, pp. 227-235
-
-
Jennings, K.R.1
-
41
-
-
0000089482
-
Surface-induced dissociation ofmolecular ions
-
Ion Processes
-
M. A. Mabud, M. J. Dekrey, and R. G. Cooks, Surface-induced dissociation ofmolecular ions, Int. J. Mass Spectrom. Ion Processes 67 (1985), 285-294.
-
(1985)
Int. J. Mass Spectrom
, vol.67
, pp. 285-294
-
-
Mabud, M.A.1
Dekrey, M.J.2
Cooks, R.G.3
-
42
-
-
0004024840
-
Metastable Ions
-
Elsevier, Amsterdam, The Netherlands
-
R. G. Cooks, J. H. Beynon, R. M. Caprioli, and G. R. Lester, Metastable Ions, Elsevier, Amsterdam, The Netherlands, 1973.
-
(1973)
-
-
Cooks, R.G.1
Beynon, J.H.2
Caprioli, R.M.3
Lester, G.R.4
-
43
-
-
33947093279
-
Selected ion fragmentation with a tandem quadrupolemass spectrometer
-
R. A.Yost and C.G. Enke, Selected ion fragmentation with a tandem quadrupolemass spectrometer, J. Am. Chem. Soc. 100 (1978), 2274-2275.
-
(1978)
J. Am. Chem. Soc.
, vol.100
, pp. 2274-2275
-
-
Yost, R.A.1
Enke, C.G.2
-
44
-
-
0034852208
-
An introduction to quadrupole-time-of-flight mass spectrometry
-
J. Mass Spectrom
-
I.V. Chernushevich, A.V. Loboda, and B.A.Thomson, An introduction to quadrupole-time-of-flight mass spectrometry, J. Mass Spectrom. 36 (2001), 849-865.
-
(2001)
, vol.36
, pp. 849-865
-
-
Chernushevich, I.V.1
Loboda, A.V.2
Thomson, B.A.3
-
45
-
-
4444272971
-
Triple quadrupole linear ion trap mass spectrometer for the analysis ofsmall molecules and macromolecules
-
J. Mass Spectrom
-
G. Hopfgartner, E. Varesio, V. Tschaeppaet, C. Grivet, E. Bourgogne, and L. A.Leuthold, Triple quadrupole linear ion trap mass spectrometer for the analysis ofsmall molecules and macromolecules, J. Mass Spectrom. 39 (2004), 845-855.
-
(2004)
, vol.39
, pp. 845-855
-
-
Hopfgartner, G.1
Varesio, E.2
Tschaeppaet, V.3
Grivet, C.4
Bourgogne, E.5
Leuthold, L.A.6
-
46
-
-
3042765151
-
Novel linearquadrupole ion trap/FT mass spectrometer: Performance characterization anduse in the comparative analysis of histone H3 post-translational modifications
-
J. E. P. Syka, J. A. Marto, D. L. Bai, S. Horning, and M. W. Senko, Novel linearquadrupole ion trap/FT mass spectrometer: Performance characterization anduse in the comparative analysis of histone H3 post-translational modifications.J. Proteome Res. 3 (2004), 621-626.
-
(2004)
J. Proteome Res.
, vol.3
, pp. 621-626
-
-
Syka, J.E.P.1
Marto, J.A.2
Bai, D.L.3
Horning, S.4
Senko, M.W.5
-
47
-
-
0030851423
-
Wrong-way-round electrosprayionization of amino acids
-
B. A. Mansoori, D. A. Volmer, and R. K. Boyd, Wrong-way-round electrosprayionization of amino acids, Rapid Commun. Mass Spectrom. 11 (1997), 1120-1130.
-
(1997)
Rapid Commun. Mass Spectrom.
, vol.11
, pp. 1120-1130
-
-
Mansoori, B.A.1
Volmer, D.A.2
Boyd, R.K.3
-
48
-
-
0034488948
-
Protonation in electrospray mass spectrometry: Wrongway-round or right-way-round
-
S. Zhou and K. D. Cook, Protonation in electrospray mass spectrometry: Wrongway-round or right-way-round? J. Am. Soc. Mass Spectrom. 11 (2000), 961-966.
-
(2000)
J. Am. Soc. Mass Spectrom
, vol.11
, pp. 961-966
-
-
Zhou, S.1
Cook, K.D.2
-
49
-
-
12044257680
-
Electrospray-ion spray: A comparisonof mechanisms and performance
-
M. G. Ikonomou, A. T. Blades, and P. Kebarle, Electrospray-ion spray: A comparisonof mechanisms and performance, Anal. Chem. 63 (1991), 1989-1998.
-
(1991)
Anal. Chem
, vol.63
, pp. 1989-1998
-
-
Ikonomou, M.G.1
Blades, A.T.2
Kebarle, P.3
-
50
-
-
0037090377
-
Quantitativedetermination of noncovalent binding interactions using soft ionization massspectrometry
-
J. M. Daniel, S. D. Friess, S. Rajagopalan, S.Wendt, and R. Zenobi, Quantitativedetermination of noncovalent binding interactions using soft ionization massspectrometry, Int. J. Mass Spectrom. 216 (2002), 1-27.340
-
(2002)
Int. J. Mass Spectrom.
, vol.216
-
-
Daniel, J.M.1
Friess, S.D.2
Rajagopalan, S.3
Wendt, S.4
Zenobi, R.5
-
51
-
-
0034716183
-
Probing molecular recognition by mass spectrometry
-
J. S. Brodbelt, Probing molecular recognition by mass spectrometry, Int. J. MassSpectrom. 200 (2000), 57-69.
-
(2000)
Int. J. MassSpectrom
, vol.200
, pp. 57-69
-
-
Brodbelt, J.S.1
-
52
-
-
0001861342
-
Analytical applications of ion-molecule reactions
-
J. S. Brodbelt, Analytical applications of ion-molecule reactions, Mass Spectrom.Rev. 16 (1997), 91-110.
-
(1997)
Mass Spectrom.Rev
, vol.16
, pp. 91-110
-
-
Brodbelt, J.S.1
-
53
-
-
33845471401
-
Negative ion production with the electrospray ionsource
-
M. Yamashita and J. B. Fenn, Negative ion production with the electrospray ionsource, J. Phys. Chem. 88 (1984), 4671-4675.
-
(1984)
J. Phys. Chem.
, vol.88
, pp. 4671-4675
-
-
Yamashita, M.1
Fenn, J.B.2
-
54
-
-
0012728028
-
Ion-molecule equilibria, how and why
-
P. Kebarle, Ion-molecule equilibria, how and why, J. Am. Soc. Mass Spectrom.3 (1992), 1-9.
-
(1992)
J. Am. Soc. Mass Spectrom.
, vol.3
, pp. 1-9
-
-
Kebarle, P.1
-
55
-
-
0009031833
-
Effect of the conductivity of the electrosprayed solutionon the electrospray current
-
Factors determining analyte sensitivity in electrospraymass spectrometry
-
L. Tang and P. Kebarle, Effect of the conductivity of the electrosprayed solutionon the electrospray current. Factors determining analyte sensitivity in electrospraymass spectrometry, Anal. Chem. 63 (1991), 2709-2715.
-
(1991)
Anal. Chem.
, vol.63
, pp. 2709-2715
-
-
Tang, L.1
Kebarle, P.2
-
56
-
-
0000648747
-
Investigations of the electrosprayinterface for liquid chromatography/mass spectrometry
-
M. G. Ikonomou, A. T. Blades, and P. Kebarle, Investigations of the electrosprayinterface for liquid chromatography/mass spectrometry, Anal. Chem. 62 (1990),957-967.
-
(1990)
Anal. Chem.
, vol.62
, pp. 957-967
-
-
Ikonomou, M.G.1
Blades, A.T.2
Kebarle, P.3
-
57
-
-
0029915411
-
Correlation between solvation energiesand electrospray mass spectrometric response factors.
-
Study by electrospraymass spectrometry of supramolecular complexes in thermodynamic equilibriumin solution J. Mass Spectrom
-
E. Leize, A. Jaffrezic, and A.Van Dorsselaer, Correlation between solvation energiesand electrospray mass spectrometric response factors. Study by electrospraymass spectrometry of supramolecular complexes in thermodynamic equilibriumin solution, J. Mass Spectrom. 31 (1996), 537-544.
-
(1996)
, vol.31
, pp. 537-544
-
-
Leize, E.1
Jaffrezic, A.2
Van Dorsselaer, A.3
-
58
-
-
0030573056
-
Application of liquid chromatography-atmosphericpressure ionization mass spectrometry in natural product analysis
-
Evaluation andoptimization of electrospray and heated nebulizer interfaces
-
S. Zhou and M. Hamburger, Application of liquid chromatography-atmosphericpressure ionization mass spectrometry in natural product analysis. Evaluation andoptimization of electrospray and heated nebulizer interfaces, J. Chromatogr.A 755(1996), 189-204.
-
(1996)
J. Chromatogr.A
, vol.755
, pp. 189-204
-
-
Zhou, S.1
Hamburger, M.2
-
59
-
-
0036671264
-
Adduct formation in electrospray ionization. Part 1:Common acidic pharmaceuticals
-
K. Schug and H. M. McNair, Adduct formation in electrospray ionization. Part 1:Common acidic pharmaceuticals, J. Sep. Sci. 25 (2002), 760-766.
-
(2002)
J. Sep. Sci.
, vol.25
, pp. 760-766
-
-
Schug, K.1
McNair, H.M.2
-
60
-
-
0037462525
-
Adduct formation in electrospray ionization massspectrometry II. Benzoic acid derivatives
-
K. Schug and H. M. McNair, Adduct formation in electrospray ionization massspectrometry II. Benzoic acid derivatives, J. Chromatogr.A 985 (2003), 531-539.
-
(2003)
J. Chromatogr.A
, vol.985
, pp. 531-539
-
-
Schug, K.1
McNair, H.M.2
-
61
-
-
84886450322
-
Loss of hydroxyl radical in CADMS/MS for identification of oxidized drug metabolites
-
Proceedings of the 52ndASMS Conference on Mass Spectrometry and Allied Topics May 23-27,, Nashville, Tennessee.
-
X.-G. Zhao, J. Ma, H. Feng, J.Wu, and Z.-M. Gu, Loss of hydroxyl radical in CADMS/MS for identification of oxidized drug metabolites, Proceedings of the 52ndASMS Conference on Mass Spectrometry and Allied Topics May 23-27, 2004, Nashville, Tennessee.
-
(2004)
-
-
Zhao, X.-G.1
Ma, J.2
Feng, H.3
Wu, J.4
Gu, Z.-M.5
-
62
-
-
0038788807
-
Exactmass measurement of product ions for the structural confirmation and identificationof unknown compounds using a quadrupole time-of-flight spectrometer: Asimplified approach using combined tandem mass spectrometric functions
-
K. Clauwaert, S.Vande Casteele, B. Sinnaeve, D. Deforce, and W. Lambert, Exactmass measurement of product ions for the structural confirmation and identificationof unknown compounds using a quadrupole time-of-flight spectrometer: Asimplified approach using combined tandem mass spectrometric functions, RapidCommun. Mass Spectrom. 17 (2003), 1443-1448.
-
(2003)
RapidCommun. Mass Spectrom.
, vol.17
, pp. 1443-1448
-
-
Clauwaert, K.1
Vande Casteele, S.2
Sinnaeve, B.3
Deforce, D.4
Lambert, W.5
-
63
-
-
0035356597
-
Accurate mass liquidchromatography/mass spectrometry on quadrupole orthogonal acceleration timeof-flight mass analyzers using switching between separate sample and referencesprays
-
2. Applications using the dual-electrospray ion source
-
J.-C.Wolff, C. Eckers, A. B. Sage, K. Giles, and R. Bateman, Accurate mass liquidchromatography/mass spectrometry on quadrupole orthogonal acceleration timeof-flight mass analyzers using switching between separate sample and referencesprays. 2. Applications using the dual-electrospray ion source, Anal. Chem. 73(2001), 2605-2612.
-
(2001)
Anal. Chem.
, vol.73
, pp. 2605-2612
-
-
Wolff, J.-C.1
Eckers, C.2
Sage, A.B.3
Giles, K.4
Bateman, R.5
-
64
-
-
0034536050
-
Identification of an N-(hydroxysulfonyl)oxy metabolite using in vitro microorganism screening
-
high-resolutionand tandem electrospray ionization mass spectrometry
-
S. Ilard, F. Caradec, P. Jackson, and W. Luijten, Identification of an N-(hydroxysulfonyl)oxy metabolite using in vitro microorganism screening, high-resolutionand tandem electrospray ionization mass spectrometry, Rapid Commun. MassSpectrom. 14 (2000), 2362-2366.
-
(2000)
Rapid Commun. MassSpectrom.
, vol.14
, pp. 2362-2366
-
-
Ilard, S.1
Caradec, F.2
Jackson, P.3
Luijten, W.4
-
65
-
-
0003830080
-
Interpretation of Mass Spectra
-
3rd ed., University Science Books,Mill Valley, CA
-
F.W. McLafferty, Interpretation of Mass Spectra, 3rd ed., University Science Books,Mill Valley, CA, 1980. 341
-
(1980)
, pp. 341
-
-
McLafferty, F.W.1
-
66
-
-
0034716211
-
Charge-remote fragmentation: An account of research on mechanismsand applications
-
M. L. Gross, Charge-remote fragmentation: An account of research on mechanismsand applications, Int. J. Mass Spectrom. 200 (2000), 611-624.
-
(2000)
Int. J. Mass Spectrom.
, vol.200
, pp. 611-624
-
-
Gross, M.L.1
-
67
-
-
0034327110
-
Applications and mechanisms of charge-remote fragmentation
-
C. Cheng and M. L. Gross, Applications and mechanisms of charge-remote fragmentation,Mass Spectrom. Rev. 19 (2000), 398-420.
-
(2000)
Mass Spectrom. Rev.
, vol.19
, pp. 398-420
-
-
Cheng, C.1
Gross, M.L.2
-
68
-
-
0027473851
-
Charge-remote fragmentations for structuraldetermination of lipids
-
J. Adams and M. J. Songer, Charge-remote fragmentations for structuraldetermination of lipids, TrAC, Trends Anal. Chem. 12 (1993), 28-36.
-
(1993)
TrAC, Trends Anal. Chem.
, vol.12
, pp. 28-36
-
-
Adams, J.1
Songer, M.J.2
-
69
-
-
44049112946
-
Charge-remote fragmentations: Method, mechanism and applications
-
Ion Processes
-
M. L. Gross, Charge-remote fragmentations: Method, mechanism and applications,Int. J. Mass Spectrom. Ion Processes 118-119 (1992), 137-165.
-
(1992)
Int. J. Mass Spectrom.
, vol.118
, pp. 137-165
-
-
Gross, M.L.1
-
70
-
-
0000543410
-
Charge-remote fragmentations: analytical applications and fundamentalstudies
-
J. Adams, Charge-remote fragmentations: analytical applications and fundamentalstudies, Mass Spectrom. Rev. 9 (1990), 141-186.
-
(1990)
Mass Spectrom. Rev.
, vol.9
, pp. 141-186
-
-
Adams, J.1
-
71
-
-
0004127585
-
Handbook of CombinatorialChemistry
-
Drugs, Catalysts, Materials, John Wiley & Sons, New York
-
K. C. Nicolaou, R. Hanko, and W. Hartwig, Handbook of CombinatorialChemistry, Volume 1: Drugs, Catalysts, Materials, John Wiley & Sons, New York,2002.
-
(2002)
, vol.1
-
-
Nicolaou, K.C.1
Hanko, R.2
Hartwig, W.3
-
72
-
-
0038440390
-
Progress in liquid chromatography-mass spectrometry instrumentationand its impact on high-throughput screening
-
W. M. A. Niessen, Progress in liquid chromatography-mass spectrometry instrumentationand its impact on high-throughput screening, J. Chromatogr. A 1000(2003), 413-436.
-
(2003)
J. Chromatogr. A
, vol.1000
, pp. 413-436
-
-
Niessen, W.M.A.1
-
73
-
-
0035674233
-
Mass spectrometryand combinatorial chemistry: A short outline
-
J. Mass Spectrom
-
A. Triolo, M. Altamura, F. Cardinali, A. Sisto, and C. A. Maggi, Mass spectrometryand combinatorial chemistry: A short outline, J. Mass Spectrom. 36 (2001),1249-1259.
-
(2001)
, vol.36
, pp. 1249-1259
-
-
Triolo, A.1
Altamura, M.2
Cardinali, F.3
Sisto, A.4
Maggi, C.A.5
-
75
-
-
21544474431
-
High-throughput characterization of combinatoriallibraries generated by parallel synthesis
-
J. N. Kyranos and J. C. Hogan, High-throughput characterization of combinatoriallibraries generated by parallel synthesis, Anal. Chem. 70 (1998), 389A-395A.
-
(1998)
Anal. Chem.
, vol.70
-
-
Kyranos, J.N.1
Hogan, J.C.2
-
76
-
-
0002974025
-
Mass spectrometry in the combinatorial chemistry revolution
-
J.A. Loo, Mass spectrometry in the combinatorial chemistry revolution, Eur. MassSpectrom. 3 (1997), 93-104.
-
(1997)
Eur. MassSpectrom.
, vol.3
, pp. 93-104
-
-
Loo, J.A.1
-
77
-
-
0035715939
-
Analysis and screening of combinatoriallibraries using mass spectrometry
-
Y. G. Shin and R. B. van Breemen, Analysis and screening of combinatoriallibraries using mass spectrometry, Biopharm. Drug Dispos. 22 (2001), 353-372.
-
(2001)
Biopharm. Drug Dispos.
, vol.22
, pp. 353-372
-
-
Shin, Y.G.1
Van Breemen, R.B.2
-
78
-
-
0034182316
-
Mass spectrometry in combinatorialchemistry
-
C. Enjalbal, J. Martinez, and J. L.Aubagnac, Mass spectrometry in combinatorialchemistry, Mass Spectrom. Rev. 19 (2000), 139-161.
-
(2000)
Mass Spectrom. Rev.
, vol.19
, pp. 139-161
-
-
Enjalbal, C.1
Martinez, J.2
Aubagnac, J.L.3
-
79
-
-
0037774451
-
Parallel highthroughputaccurate mass measurement using a nine-channel multiplexedelectrospray liquid chromatography ultraviolet time-of-flight mass spectrometrysystem
-
L. Fang, M. Demee, J. Cournoyer, T. Sierra, C. Young, and B. Yan, Parallel highthroughputaccurate mass measurement using a nine-channel multiplexedelectrospray liquid chromatography ultraviolet time-of-flight mass spectrometrysystem, Rapid Commun. Mass Spectrom. 17 (2003), 1425-1432.
-
(2003)
Rapid Commun. Mass Spectrom.
, vol.17
, pp. 1425-1432
-
-
Fang, L.1
Demee, M.2
Cournoyer, J.3
Sierra, T.4
Young, C.5
Yan, B.6
-
80
-
-
85047695735
-
Evidence that a burst of DNA depurination in SENCAR mouse skin induceserror-prone repair and forms mutations in the H-ras gene
-
D. Chakravarti, P. C. Mailander, K.-M. Li, S. Higginbotham, and H. L. Zhang,Evidence that a burst of DNA depurination in SENCAR mouse skin induceserror-prone repair and forms mutations in the H-ras gene, Oncogene 20 (2001),7945-7953.
-
(2001)
Oncogene
, vol.20
, pp. 7945-7953
-
-
Chakravarti, D.1
Mailander, P.C.2
Li, K.-M.3
Higginbotham, S.4
Zhang, H.L.5
-
81
-
-
0033406099
-
Exact mass measurementsusing a 7 tesla fourier transform ion cyclotron resonance mass spectrometerin a good laboratory practices-regulated environment
-
R. D. Burton, K. P. Matuszak, C. H.Watson, and J. R. Eyler, Exact mass measurementsusing a 7 tesla fourier transform ion cyclotron resonance mass spectrometerin a good laboratory practices-regulated environment, J. Am. Soc. MassSpectrom. 10 (1999), 1291-1297.
-
(1999)
J. Am. Soc. MassSpectrom.
, vol.10
, pp. 1291-1297
-
-
Burton, R.D.1
Matuszak, K.P.2
Watson, C.H.3
Eyler, J.R.4
-
82
-
-
0030463031
-
Analysisof combinatorial libraries using electrospray Fourier transform ion cyclotron resonancemass spectrometry
-
J. P. Nawrocki, M.Wigger, C. H.Watson, T.W. Hayes, and M.W. Senko, Analysisof combinatorial libraries using electrospray Fourier transform ion cyclotron resonancemass spectrometry, Rapid Commun. Mass Spectrom. 10 (1996), 1860-1864.
-
(1996)
Rapid Commun. Mass Spectrom.
, vol.10
, pp. 1860-1864
-
-
Nawrocki, J.P.1
Wigger, M.2
Watson, C.H.3
Hayes, T.W.4
Senko, M.W.5
-
83
-
-
0033277328
-
A review of high-throughput screening approaches for drugdiscovery
-
J. W. Armstrong, A review of high-throughput screening approaches for drugdiscovery, Am. Biotechnol. Lab. 17 (1999), 26-28.342
-
(1999)
Am. Biotechnol. Lab.
, vol.17
-
-
Armstrong, J.W.1
-
84
-
-
77956764741
-
Current and future trends in high throughput screening for drugdiscovery
-
K. R. Oldenburg, Current and future trends in high throughput screening for drugdiscovery, Annu. Rep. Med. Chem. 33 (1998), 301-311.
-
(1998)
Annu. Rep. Med. Chem.
, vol.33
, pp. 301-311
-
-
Oldenburg, K.R.1
-
85
-
-
8444221197
-
An affinityselection-mass spectrometry method for the identification of small moleculeligands from self-encoded combinatorial libraries. Discovery of a novel antagonistof E. coli dihydrofolate reductase
-
D.A.Annis, J.Athanasopoulos, P. J. Curran, J. S. Felsch, and K. Kalghatgi,An affinityselection-mass spectrometry method for the identification of small moleculeligands from self-encoded combinatorial libraries. Discovery of a novel antagonistof E. coli dihydrofolate reductase, Int. J. Mass Spectrom. 238 (2004), 77-83.
-
(2004)
Int. J. Mass Spectrom.
, vol.238
, pp. 77-83
-
-
Annis, D.A.1
Athanasopoulos, J.2
Curran, P.J.3
Felsch, J.S.4
Kalghatgi, K.5
-
86
-
-
9644302954
-
A general techniqueto rank protein-ligand binding affinities and determine allosteric versusdirect binding site competition in compound mixtures
-
D. A. Annis, N. Nazef, C.-C. Chuang,M. P. Scott, and H. M. Nash, A general techniqueto rank protein-ligand binding affinities and determine allosteric versusdirect binding site competition in compound mixtures, J. Am. Chem. Soc. 126(2004), 15495-15503.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 15495-15503
-
-
Annis, D.A.1
Nazef, N.2
Chuang, C.-C.3
Scott, M.P.4
Nash, H.M.5
-
87
-
-
0031907784
-
Active drug substance impurity profiling. Part II.LC/MS/MS fingerprinting
-
E. C. Nicolas and T. H. Scholz, Active drug substance impurity profiling. Part II.LC/MS/MS fingerprinting, J. Pharm. Biomed. Anal. 16 (1998), 825-836.
-
(1998)
J. Pharm. Biomed. Anal.
, vol.16
, pp. 825-836
-
-
Nicolas, E.C.1
Scholz, T.H.2
-
88
-
-
0020322791
-
Liquid chromatography-mass spectrometry in the pharmaceutical industry:Objectives and needs
-
F. Erni, Liquid chromatography-mass spectrometry in the pharmaceutical industry:Objectives and needs, J. Chromatogr. 251 (1982), 141-151.
-
(1982)
J. Chromatogr.
, vol.251
, pp. 141-151
-
-
Erni, F.1
-
89
-
-
0030857915
-
Profiling degradants of paclitaxelusing liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry substructural techniques
-
K. J.Volk, S. E. Hill, E. H. Kerns, and M. S. Lee, Profiling degradants of paclitaxelusing liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry substructural techniques, J. Chromatogr. B: Biomed.Sci. Appl. 696 (1997), 99-115.
-
(1997)
J. Chromatogr. B: Biomed.Sci. Appl.
, vol.696
, pp. 99-115
-
-
Volk, K.J.1
Hill, S.E.2
Kerns, E.H.3
Lee, M.S.4
-
90
-
-
0030249373
-
Predictivestrategy for the rapid structure elucidation of drug degradants
-
R. A. Rourick, K. J. Volk, S. E. Klohr, T. Spears, E. H. Kerns, and M. S. Lee, Predictivestrategy for the rapid structure elucidation of drug degradants, J. Pharm.Biomed. Anal. 14 (1996), 1743-1752.
-
(1996)
J. Pharm.Biomed. Anal.
, vol.14
, pp. 1743-1752
-
-
Rourick, R.A.1
Volk, K.J.2
Klohr, S.E.3
Spears, T.4
Kerns, E.H.5
Lee, M.S.6
-
91
-
-
0033128171
-
LC/MS applications in drug development
-
M. S. Lee and E. H. Kerns, LC/MS applications in drug development, Mass Spectrom.Rev. 18 (1999), 187-279.
-
(1999)
Mass Spectrom.Rev.
, vol.18
, pp. 187-279
-
-
Lee, M.S.1
Kerns, E.H.2
-
92
-
-
0034993619
-
-
Structural characterizationof the oxidative degradation products of an antifungal agent SCH 56592 by LCNMRand LC-MS
-
W. Feng,H. Liu,G. Chen, R. Malchow, and F. Bennett, Structural characterizationof the oxidative degradation products of an antifungal agent SCH 56592 by LCNMRand LC-MS, J. Pharm. Biomed. Anal. 25 (2001), 545-557.
-
(2001)
J. Pharm. Biomed. Anal.
, vol.25
, pp. 545-557
-
-
Feng, W.1
Liu, H.2
Chen, G.3
Malchow, R.4
Bennett, F.5
-
93
-
-
0033824375
-
The use of liquid chromatography-mass spectrometry for the identificationof drug degradation products in pharmaceutical formulations
-
Y. Wu, The use of liquid chromatography-mass spectrometry for the identificationof drug degradation products in pharmaceutical formulations, Biomed. Chromatogr.14 (2000), 384-396.
-
(2000)
Biomed. Chromatogr.
, vol.14
, pp. 384-396
-
-
Wu, Y.1
-
94
-
-
0033672748
-
HighresolutionLC/MS for analysis of minor components in complex mixtures:Negative ion ESI for identification of impurities and degradation products of anovel oligosaccharide antibiotic
-
J. Mass Spectrom
-
P. A. Shipkova, L. Heimark, P. L. Bartner, G. Chen, and B. N. Pramanik, HighresolutionLC/MS for analysis of minor components in complex mixtures:Negative ion ESI for identification of impurities and degradation products of anovel oligosaccharide antibiotic, J. Mass Spectrom. 35 (2000), 1252-1258.
-
(2000)
, vol.35
, pp. 1252-1258
-
-
Shipkova, P.A.1
Heimark, L.2
Bartner, P.L.3
Chen, G.4
Pramanik, B.N.5
-
95
-
-
0032968276
-
Identification of losartan degradatesin stressed tablets by LC-MS and LC-MS/MS
-
Z. Zhao,Q.Wang, E.W. Tsai, X. Z. Qin, and D. Ip, Identification of losartan degradatesin stressed tablets by LC-MS and LC-MS/MS, J. Pharm. Biomed. Anal. 20(1999), 129-136.
-
(1999)
J. Pharm. Biomed. Anal.
, vol.20
, pp. 129-136
-
-
Zhao, Z.1
Wang, Q.2
Tsai, E.W.3
Qin, X.Z.4
Ip, D.5
-
96
-
-
0001957715
-
Characterization of pharmaceutical compoundsand related substances by using HPLC FTICR-MS and tandem mass spectrometry
-
B. E.Winger and C. A. J. Kemp, Characterization of pharmaceutical compoundsand related substances by using HPLC FTICR-MS and tandem mass spectrometry.Am. Pharm. Rev. 4 (2001), 55-63.
-
(2001)
Am. Pharm. Rev.
, vol.4
, pp. 55-63
-
-
Winger, B.E.1
Kemp, C.A.J.2
-
97
-
-
14744267430
-
Accurate mass measurementsby Fourier transfor mass spectrometry
-
L.-K. Zhang, D. Rempel, B. N. Pramanik, and M. L. Gross, Accurate mass measurementsby Fourier transfor mass spectrometry, Mass Spectrom. Rev. 24 (2005),286-309.
-
(2005)
Mass Spectrom. Rev.
, vol.24
, pp. 286-309
-
-
Zhang, L.-K.1
Rempel, D.2
Pramanik, B.N.3
Gross, M.L.4
-
98
-
-
1642452711
-
Determination of ketotifen in humanplasma by LC-MS
-
F.Q. Alali,B. M.Tashtoush, and N. M. Najib, Determination of ketotifen in humanplasma by LC-MS, J. Pharm. Biomed. Anal. 34 (2004), 87-94.
-
(2004)
J. Pharm. Biomed. Anal.
, vol.34
, pp. 87-94
-
-
Alali, F.Q.1
Tashtoush, B.M.2
Najib, N.M.3
-
100
-
-
0031900683
-
Atmospheric pressure ionization LC/MS/MS techniquesfor drug disposition studies
-
E. Brewer and J. Henion,Atmospheric pressure ionization LC/MS/MS techniquesfor drug disposition studies, J. Pharm. Sci. 87 (1998), 395-402.
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 395-402
-
-
Brewer, E.1
Henion, J.2
-
101
-
-
0033824707
-
High-throughput quantitative bioanalysis by LC/MS/MS
-
M. Jemal, High-throughput quantitative bioanalysis by LC/MS/MS, Biomed.Chromatogr. 14 (2000), 422-429.
-
(2000)
Biomed.Chromatogr.
, vol.14
, pp. 422-429
-
-
Jemal, M.1
-
102
-
-
0036234877
-
Automated sample preparation and LC-MS for high-throughputADME quantification
-
D. O'Connor, Automated sample preparation and LC-MS for high-throughputADME quantification, Curr. Opin. Drug Discovery Dev. 5 (2002), 52-58.
-
(2002)
Curr. Opin. Drug Discovery Dev.
, vol.5
, pp. 52-58
-
-
O'Connor, D.1
-
103
-
-
7844247581
-
Quantitativedetermination of Eteinascidin 743 in human plasma by miniaturized highperformanceliquid chromatography coupled with electrospray ionization tandemmass spectrometry
-
J. Mass Spectrom
-
H. Rosing, M. J. X. Hillebrand, J. M. Jimeno, A. Gomez, and P. Floriano, Quantitativedetermination of Eteinascidin 743 in human plasma by miniaturized highperformanceliquid chromatography coupled with electrospray ionization tandemmass spectrometry, J. Mass Spectrom. 33 (1998), 1134-1140.
-
(1998)
, vol.33
, pp. 1134-1140
-
-
Rosing, H.1
Hillebrand, M.J.X.2
Jimeno, J.M.3
Gomez, A.4
Floriano, P.5
-
104
-
-
0042697374
-
Quantitative high-throughput analysis of drugsin biological matrices by mass spectrometry
-
G. Hopfgartner and E. Bourgogne, Quantitative high-throughput analysis of drugsin biological matrices by mass spectrometry, Mass Spectrom. Rev. 22 (2003),195-214.
-
(2003)
Mass Spectrom. Rev.
, vol.22
, pp. 195-214
-
-
Hopfgartner, G.1
Bourgogne, E.2
-
105
-
-
0036918663
-
Development and application of singlecolumndirect plasma injection procedures for drug candidate assays using HPLCMS/MS
-
Y. Hsieh, K. Ng, and W. A. Korfmacher, Development and application of singlecolumndirect plasma injection procedures for drug candidate assays using HPLCMS/MS, Am. Pharm. Rev. 5 (2002), 88-90.
-
(2002)
Am. Pharm. Rev.
, vol.5
, pp. 88-90
-
-
Hsieh, Y.1
Ng, K.2
Korfmacher, W.A.3
-
106
-
-
0036218957
-
Rapid determination of pharmacokineticproperties of new chemical entities: In vivo approaches
-
K. A. Cox, R. E.White, and W. A. Korfmacher, Rapid determination of pharmacokineticproperties of new chemical entities: In vivo approaches, Comb. Chem.High Throughput Screening 5 (2002), 29-37.
-
(2002)
Comb. Chem.High Throughput Screening
, vol.5
, pp. 29-37
-
-
Cox, K.A.1
White, R.E.2
Korfmacher, W.A.3
-
107
-
-
0033136333
-
Novel in vivo procedure for rapid pharmacokinetic screening of discovery compoundsin rats
-
K. A. Cox, K. Dunn-Meynell, W. A. Korfmacher, L. Broske, and A. A. Nomeir,Novel in vivo procedure for rapid pharmacokinetic screening of discovery compoundsin rats, Drug Discovery Today 4 (1999), 232-237.
-
(1999)
Drug Discovery Today
, vol.4
, pp. 232-237
-
-
Cox, K.A.1
Dunn-Meynell, K.2
Korfmacher, W.A.3
Broske, L.4
Nomeir, A.A.5
-
108
-
-
85056489031
-
Using Mass Spectrometry for Drug Metabolism Studies
-
Taylor & Francis CRC Press, Boca Raton, FL,
-
W. A. Korfmacher (ed.), Using Mass Spectrometry for Drug Metabolism Studies,Taylor & Francis CRC Press, Boca Raton, FL, 2005.
-
(2005)
-
-
Korfmacher, W.A.1
-
109
-
-
0036253527
-
The resurgence of column switchingtechniques to facilitate rapid LC/MS/MS based bioanalysis in drug discovery
-
B. L.Ackermann,A.T. Murphy, and M. J. Berna,The resurgence of column switchingtechniques to facilitate rapid LC/MS/MS based bioanalysis in drug discovery,Am. Pharm. Rev. 5 (2002), 54-63.
-
(2002)
Am. Pharm. Rev.
, vol.5
, pp. 54-63
-
-
Ackermann, B.L.1
Murphy, A.T.2
Berna, M.J.3
-
110
-
-
0343013474
-
Fully-automated assay by liquid chromatography forroutine drug monitoring in body fluids-method development with biologicalsamples
-
W. Roth and K. Beschke, Fully-automated assay by liquid chromatography forroutine drug monitoring in body fluids-method development with biologicalsamples, J. Pharm. Biomed. Anal. 2 (1984), 289-296.
-
(1984)
J. Pharm. Biomed. Anal.
, vol.2
, pp. 289-296
-
-
Roth, W.1
Beschke, K.2
-
111
-
-
0019431663
-
Fully automated highperformanceliquid chromatography
-
A new chromatograph for pharmacokineticdrug monitoring by direct injection of body fluids
-
W. Roth, K. Beschke, R. Jauch, A. Zimmer, and F.W. Koss, Fully automated highperformanceliquid chromatography. A new chromatograph for pharmacokineticdrug monitoring by direct injection of body fluids, J. Chromatogr. 222 (1981),13-22.
-
(1981)
J. Chromatogr.
, vol.222
, pp. 13-22
-
-
Roth, W.1
Beschke, K.2
Jauch, R.3
Zimmer, A.4
Koss, F.W.5
-
112
-
-
1842833762
-
Recent advances in use ofLC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery
-
B. L. Ackermann, M. J. Berna, and A. T. Murphy, Recent advances in use ofLC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery,Curr. Top. Med. Chem. B (2002), 53-66.
-
(2002)
Curr. Top. Med. Chem. B
, pp. 53-66
-
-
Ackermann, B.L.1
Berna, M.J.2
Murphy, A.T.3
-
113
-
-
1942516814
-
Simple and sensitiveliquid chromatographic quantitative analysis of the novel marine anticancer drugYondelis (ET-743, trabectedin) in human plasma using column switching andtandem mass spectrometric detection
-
J. Mass Spectrom
-
E. Stokvis, H. Rosing, L. Lopez-Lazaro, and J. H. Beijnen, Simple and sensitiveliquid chromatographic quantitative analysis of the novel marine anticancer drugYondelis (ET-743, trabectedin) in human plasma using column switching andtandem mass spectrometric detection, J. Mass Spectrom. 39 (2004), 431-436.
-
(2004)
, vol.39
, pp. 431-436
-
-
Stokvis, E.1
Rosing, H.2
Lopez-Lazaro, L.3
Beijnen, J.H.4
-
114
-
-
4344625870
-
A study of matrix effects on an LC/MS/MSassay for olanzapine and desmethyl olanzapine
-
C. Chin, Z. P. Zhang, and H.T. Karnes, A study of matrix effects on an LC/MS/MSassay for olanzapine and desmethyl olanzapine, J. Pharm. Biomed. Anal. 35(2004), 1149-1167.
-
(2004)
J. Pharm. Biomed. Anal.
, vol.35
, pp. 1149-1167
-
-
Chin, C.1
Zhang, Z.P.2
Karnes, H.T.3
-
115
-
-
4344663297
-
Switching from an analogous to a stable isotopically labeled internal standard for344 the LC-MS/MS quantitation of the novel anticancer drug Kahalalide F significantlyimproves assay performance
-
E. Stokvis, H. Rosing, L. Lopez-Lazaro, J. H. M. Schellens, and J. H. Beijnen,Switching from an analogous to a stable isotopically labeled internal standard for344 the LC-MS/MS quantitation of the novel anticancer drug Kahalalide F significantlyimproves assay performance, Biomed. Chromatogr. 18 (2004), 400-402.
-
(2004)
Biomed. Chromatogr.
, vol.18
, pp. 400-402
-
-
Stokvis, E.1
Rosing, H.2
Lopez-Lazaro, L.3
Schellens, J.H.M.4
Beijnen, J.H.5
-
116
-
-
0037214121
-
Investigation of matrix effects inbioanalytical high-performance liquid chromatography/tandem mass spectrometricassays: Application to drug discovery
-
H. Mei,Y. Hsieh, C. Nardo, X. Xu, and S.Wang, Investigation of matrix effects inbioanalytical high-performance liquid chromatography/tandem mass spectrometricassays: Application to drug discovery, Rapid Commun. Mass Spectrom. 17(2003), 97-103.
-
(2003)
Rapid Commun. Mass Spectrom.
, vol.17
, pp. 97-103
-
-
Mei, H.1
Hsieh, Y.2
Nardo, C.3
Xu, X.4
Wang, S.5
-
117
-
-
8444250979
-
Matrix effect in LC-ESI-MS and LCAPCI-MS with off-line and on-line extraction procedures
-
S. Souverain, S. Rudaz, and J.-L. Veuthey, Matrix effect in LC-ESI-MS and LCAPCI-MS with off-line and on-line extraction procedures, J. Chromatogr.A 1058(2004), 61-66.
-
(2004)
J. Chromatogr.A
, vol.1058
, pp. 61-66
-
-
Souverain, S.1
Rudaz, S.2
Veuthey, J.-L.3
-
118
-
-
12844276773
-
The ion suppression phenomenon in liquid chromatography-mass spectrometryand its consequences in the field of residue analysis
-
J.-P. Antignac, K. de Wasch, F. Monteau, H. De Brabander, F. Andre, and B. LeBizec, The ion suppression phenomenon in liquid chromatography-mass spectrometryand its consequences in the field of residue analysis, Anal. Chim. Acta529 (2005), 129-136.
-
(2005)
Anal. Chim. Acta
, vol.529
, pp. 129-136
-
-
Antignac, J.-P.1
De Wasch, K.2
Monteau, F.3
De Brabander, H.4
Andre, F.5
LeBizec, B.6
-
119
-
-
0142195729
-
Matrix effect in bioanalysisof illicit drugs with LC-MS/MS: Influence of ionization type, samplepreparation, and biofluid
-
R. Dams, M. A. Huestis,W. E. Lambert, and C. M. Murphy, Matrix effect in bioanalysisof illicit drugs with LC-MS/MS: Influence of ionization type, samplepreparation, and biofluid, J. Am. Soc. Mass Spectrom. 14 (2003), 1290-1294.
-
(2003)
J. Am. Soc. Mass Spectrom.
, vol.14
, pp. 1290-1294
-
-
Dams, R.1
Huestis, M.A.2
Lambert, W.E.3
Murphy, C.M.4
-
120
-
-
0004049482
-
Integrationof Pharmaceutical Discovery and Development: Case Histories
-
Kluwer AcademicPublishers, Dordrecht, The Netherlands
-
R. T. Borchardt, R. M. Freidinger, T. K. Sawyer, and P. L. Smith (eds.), Integrationof Pharmaceutical Discovery and Development: Case Histories, Kluwer AcademicPublishers, Dordrecht, The Netherlands, 1998.
-
(1998)
-
-
Borchardt, R.T.1
Freidinger, R.M.2
Sawyer, T.K.3
Smith, P.L.4
-
121
-
-
12344263826
-
Strategies for characterization of drug metabolitesusing liquid chromatography-tandem mass spectrometry in conjunction withchemical derivatization and on-line H/D exchange approaches
-
D. Q. Liu and C. E. C. A. Hop, Strategies for characterization of drug metabolitesusing liquid chromatography-tandem mass spectrometry in conjunction withchemical derivatization and on-line H/D exchange approaches, J. Pharm. Biomed.Anal. 37 (2005), 1-18.
-
(2005)
J. Pharm. Biomed.Anal.
, vol.37
, pp. 1-18
-
-
Liu, D.Q.1
Hop, C.E.C.A.2
-
122
-
-
84886527136
-
Application of high throughput LC/MS on drugmetabolism and pharmacokinetics in drug discovery
-
J. Mass Spectrom
-
F. Naganeo and K. Iwasaki, Application of high throughput LC/MS on drugmetabolism and pharmacokinetics in drug discovery, J. Mass Spectrom. Soc. Jpn52 (2004), 137-141.
-
(2004)
, vol.52
, pp. 137-141
-
-
Naganeo, F.1
Iwasaki, K.2
-
123
-
-
84886536165
-
Drug discovery and development in the post-genome era. Can werationally design safer drugs
-
T. A. Baillie, Drug discovery and development in the post-genome era. Can werationally design safer drugs? Adv. Mass Spectrom. 16 (2004), 1-18.
-
(2004)
Adv. Mass Spectrom.
, vol.16
, pp. 1-18
-
-
Baillie, T.A.1
-
124
-
-
2442586742
-
Applications of quadrupole-time-of-flight mass spectrometry tofacilitate metabolite identification
-
C. E. C. A. Hop, Applications of quadrupole-time-of-flight mass spectrometry tofacilitate metabolite identification, Am. Pharm. Rev. 7 (2004), 76-79.
-
(2004)
Am. Pharm. Rev.
, vol.7
, pp. 76-79
-
-
Hop, C.E.C.A.1
-
125
-
-
0042530416
-
Lead optimization strategies as part of a drug metabolism environment
-
W.A.Korfmacher, Lead optimization strategies as part of a drug metabolism environment,Curr. Opin. Drug Discuss Dev. 6 (2003), 481-485.
-
(2003)
Curr. Opin. Drug Discuss Dev.
, vol.6
, pp. 481-485
-
-
Korfmacher, W.A.1
-
126
-
-
0037649064
-
Liquidchromatography/atmospheric pressure ionization-mass spectrometry in drugmetabolism studies
-
J. Mass Spectrom
-
R. Kostiainen, T. Kotiaho, T. Kuuranne, and S. Auriola, Liquidchromatography/atmospheric pressure ionization-mass spectrometry in drugmetabolism studies, J. Mass Spectrom. 38 (2003), 357-372.
-
(2003)
, vol.38
, pp. 357-372
-
-
Kostiainen, R.1
Kotiaho, T.2
Kuuranne, T.3
Auriola, S.4
-
127
-
-
1642281756
-
Drug-proteinadducts: An industry perspective on minimizing the potential for drug bioactivationin drug discovery and development
-
D. C. Evans, A. P. Watt, D. A. Nicoll-Griffith, and T. A. Baillie, Drug-proteinadducts: An industry perspective on minimizing the potential for drug bioactivationin drug discovery and development, Chem. Res. Toxicol. 17 (2004), 3-16.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 3-16
-
-
Evans, D.C.1
Watt, A.P.2
Nicoll-Griffith, D.A.3
Baillie, T.A.4
-
128
-
-
0033832991
-
Liquid chromatography-mass spectrometry in thestudy of the metabolism of drugs and other xenobiotics
-
E. J. Oliveira and D.G.Watson, Liquid chromatography-mass spectrometry in thestudy of the metabolism of drugs and other xenobiotics, Biomed. Chromatogr. 14(2000), 351-372.
-
(2000)
Biomed. Chromatogr.
, vol.14
, pp. 351-372
-
-
Oliveira, E.J.1
Watson, D.G.2
-
129
-
-
84886580825
-
Quantitative analysis of pharmaceuticals in clinical samples byLC/MS/MS method
-
N. Kobayashi, Quantitative analysis of pharmaceuticals in clinical samples byLC/MS/MS method, Gendai Kagaku Zokan 31 (1997), 284-289.
-
(1997)
Gendai Kagaku Zokan
, vol.31
, pp. 284-289
-
-
Kobayashi, N.1
-
130
-
-
0034458681
-
Present andfuture in vitro approaches for drug metabolism
-
S. Ekins, B. J. Ring, J. Grace,D. J. McRobie-Belle, and S. A. Wrighton, Present andfuture in vitro approaches for drug metabolism, J. Pharm. Toxicol. Methods 44(2000), 313-324. 345
-
(2000)
J. Pharm. Toxicol. Methods
, vol.44
-
-
Ekins, S.1
Ring, B.J.2
Grace, J.3
McRobie-Belle, D.J.4
Wrighton, S.A.5
-
131
-
-
0036320875
-
Identificationof metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytesand rat plasma
-
C. E. C. A. Hop,Y.Wang, S. Kumar, M.V. S. Elipe, and C. E. Raab, Identificationof metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytesand rat plasma, Drug Metab. Dispos. 30 (2002), 937-943.
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 937-943
-
-
Hop, C.E.C.A.1
Wang, Y.2
Kumar, S.3
Elipe, M.V.S.4
Raab, C.E.5
-
132
-
-
12244284627
-
Minimizing the potential for metabolic activation asan integral part of drug design
-
D. C. Evans and T. A. Baillie, Minimizing the potential for metabolic activation asan integral part of drug design, Curr. Opin. Drug Discovery Dev. 8 (2005), 44-50.
-
(2005)
Curr. Opin. Drug Discovery Dev.
, vol.8
, pp. 44-50
-
-
Evans, D.C.1
Baillie, T.A.2
-
133
-
-
1342344756
-
Identification of humanUDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation ofezetimibe (ZETIA)
-
A. Ghosal, N. Hapangama, Y. Yuan, J. Achanfuo-Yeboah, R. Iannucci, S.Chowdhury, K. Alton, J. E. Patrick, and S. Ziaida, Identification of humanUDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation ofezetimibe (ZETIA), Drug Metab. Dispos. 32 (2004), 314-320.
-
(2004)
Drug Metab. Dispos.
, vol.32
, pp. 314-320
-
-
Ghosal, A.1
Hapangama, N.2
Yuan, Y.3
Achanfuo-Yeboah, J.4
Iannucci, R.5
Chowdhury, S.6
Alton, K.7
Patrick, J.E.8
Ziaida, S.9
-
134
-
-
0036570099
-
Timing of new black box warnings and withdrawals for prescription medications
-
E. L. Karen, D. A. Paul, J.W. Steffie, D. U. Himmelstein, S. M.Wolfe, and D. H.Bor, Timing of new black box warnings and withdrawals for prescription medications,J. Am. Med. Assoc. 287 (2002), 2215-2220.
-
(2002)
J. Am. Med. Assoc.
, vol.287
, pp. 2215-2220
-
-
Karen, E.L.1
Paul, D.A.2
Steffie, J.W.3
Himmelstein, D.U.4
Wolfe, S.M.5
Bor, D.H.6
-
135
-
-
0013939947
-
The metabolism of 4-nitroquinoline-1-oxide, a carcinogen
-
3. An enzyme catalyzing the conversion of 4-nitroquinoline-1-oxide to 4-hydroxyaminoquinoline-1-oxide in rat liver and hepatomas
-
T. Sugimura, K. Okabe, and M. Nagao, The metabolism of 4-nitroquinoline-1-oxide, a carcinogen. 3. An enzyme catalyzing the conversion of 4-nitroquinoline-1-oxide to 4-hydroxyaminoquinoline-1-oxide in rat liver and hepatomas, CancerRes. 26 (1966), 1717-1721.
-
(1966)
CancerRes.
, vol.26
, pp. 1717-1721
-
-
Sugimura, T.1
Okabe, K.2
Nagao, M.3
-
136
-
-
0015690951
-
Mass spectra of carcinogenic 4-hydroxylaminoquinoline-N-oxides
-
T. R. Bosin and R. P. Maickel, Mass spectra of carcinogenic 4-hydroxylaminoquinoline-N-oxides, Res. Commun. Chem. Pathol. Pharmacol. 6 (1973), 813-820.
-
(1973)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.6
, pp. 813-820
-
-
Bosin, T.R.1
Maickel, R.P.2
-
137
-
-
0013943926
-
The biochemical production of ferrihemoglobin-forming derivativesfrom aromatic amines, and mechanisms of ferrihemoglobin formation
-
M. Kiese, The biochemical production of ferrihemoglobin-forming derivativesfrom aromatic amines, and mechanisms of ferrihemoglobin formation, Pharmacol.Rev. 18 (1966), 1091-1161.
-
(1966)
Pharmacol.Rev.
, vol.18
, pp. 1091-1161
-
-
Kiese, M.1
-
138
-
-
0034654478
-
Liquid chromatography/mass spectrometry methods for distinguishing N-oxidesfrom hydroxylated compounds
-
R. Ramanathan, A. D. Su, N. Alvarez, N. Blumenkrantz, and S. K. Chowdhury,Liquid chromatography/mass spectrometry methods for distinguishing N-oxidesfrom hydroxylated compounds, Anal. Chem. 72 (2000), 1352-1359.
-
(2000)
Anal. Chem.
, vol.72
, pp. 1352-1359
-
-
Ramanathan, R.1
Su, A.D.2
Alvarez, N.3
Blumenkrantz, N.4
Chowdhury, S.K.5
-
139
-
-
0035161466
-
Fragmentation of N-oxides (deoxygenation) in atmospheric pressure ionization:Investigation of the activation process
-
W. Tong, S. K. Chowdhury, J.-C. Chen, R. Zhong, K. B. Alton, and J. E. Patrick,Fragmentation of N-oxides (deoxygenation) in atmospheric pressure ionization:Investigation of the activation process, Rapid Commun. Mass Spectrom. 15 (2001),2085-2090.
-
(2001)
Rapid Commun. Mass Spectrom.
, vol.15
, pp. 2085-2090
-
-
Tong, W.1
Chowdhury, S.K.2
Chen, J.-C.3
Zhong, R.4
Alton, K.B.5
Patrick, J.E.6
-
140
-
-
0034810759
-
Use of onlinehydrogen/deuterium exchange to facilitate metabolite identification
-
D. Q. Liu, C. E. C. A. Hop, M. G. Beconi, A. Mao, and S.-H. L. Chiu, Use of onlinehydrogen/deuterium exchange to facilitate metabolite identification, RapidCommun. Mass Spectrom. 15 (2001), 1832-1839.
-
(2001)
RapidCommun. Mass Spectrom.
, vol.15
, pp. 1832-1839
-
-
Liu, D.Q.1
Hop, C.E.C.A.2
Beconi, M.G.3
Mao, A.4
Chiu, S.-H.L.5
-
141
-
-
0036211931
-
Electrospray ionization source hydrogen/deuterium exchange LC-MS and LC-MS/MS for characterization of metabolites
-
W. Lam and R. Ramanathan, In electrospray ionization source hydrogen/deuterium exchange LC-MS and LC-MS/MS for characterization of metabolites,J. Am. Soc. Mass Spectrom. 13 (2002), 345-353.
-
(2002)
J. Am. Soc. Mass Spectrom.
, vol.13
, pp. 345-353
-
-
Lam, W.1
Ramanathan, R.2
-
142
-
-
0031794872
-
Usefulness of the hydrogen-deuteriumexchange method in the study of drug metabolism using liquid chromatography-tandem mass spectrometry
-
N. Ohashi, S. Furuuchi, and M.Yoshikawa, Usefulness of the hydrogen-deuteriumexchange method in the study of drug metabolism using liquid chromatography-tandem mass spectrometry, J. Pharm. Biomed. Anal. 18 (1998), 325-334.
-
(1998)
J. Pharm. Biomed. Anal.
, vol.18
, pp. 325-334
-
-
Ohashi, N.1
Furuuchi, S.2
Yoshikawa, M.3
-
143
-
-
0003710116
-
Mass Spectrometry: Organic Chemical Applications
-
McGraw-Hill,New York
-
K. Biemann, Mass Spectrometry: Organic Chemical Applications, McGraw-Hill,New York, 1962.
-
(1962)
-
-
Biemann, K.1
-
144
-
-
0038293125
-
Quantification of protein-ligandinteractions by mass spectrometry, titration, and H/D exchange: PLIMSTEX
-
M. M. Zhu,D. L. Rempel, Z. Du, and M. L. Gross, Quantification of protein-ligandinteractions by mass spectrometry, titration, and H/D exchange: PLIMSTEX,J. Am. Chem. Soc. 125 (2003), 5252-5253.346
-
(2003)
J. Am. Chem. Soc.
, vol.125
-
-
Zhu, M.M.1
Rempel, D.L.2
Du, Z.3
Gross, M.L.4
|