Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 85, Issue 3 PART B, 2013, Pages 958-965

  Pedersen, Pernille Barbre ^a   Vilmann, Peter ^b   Bar Shalom, Daniel ^a   Müllertz, Anette ^a   Baldursdottir, Stefania ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Biological characterization; Fasted state; Human gastric fluid; Lipase activity; Physicochemical characteristics; Rheological characterization; Simulated gastric media

Indexed keywords

BILE SALT; BUFFER; FATTY ACID; LIPID EMULSION; LONG CHAIN TRIACYLGLYCEROL; PROTEIN; TRIACYLGLYCEROL LIPASE;

ADULT; ARTICLE; BLOOD VISCOSITY; CONTROLLED STUDY; DIGESTION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG SOLUBILITY; FEMALE; FLOW KINETICS; GASTRIC SUCTION; GASTROINTESTINAL TRACT; GASTROSCOPY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OSCILLATION; OSMOLALITY; PHYSICAL CHEMISTRY; PROTEIN CONTENT; REPRODUCIBILITY; SHEAR RATE; STOMACH JUICE; STOMACH PH; SURFACE TENSION;

BIOLOGICAL CHARACTERIZATION; FASTED STATE; HUMAN GASTRIC FLUID; LIPASE ACTIVITY; PHYSICOCHEMICAL CHARACTERISTICS; RHEOLOGICAL CHARACTERIZATION; SIMULATED GASTRIC MEDIA;

ADULT; AGED; BILE ACIDS AND SALTS; BUFFERS; DRUG DELIVERY SYSTEMS; FASTING; FEMALE; GASTRIC JUICE; HUMANS; HYDROGEN-ION CONCENTRATION; LIPASE; LIPIDS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; REPRODUCIBILITY OF RESULTS; RHEOLOGY; SOLUBILITY; STOMACH; SURFACE PROPERTIES; SURFACE TENSION; TIME FACTORS; VISCOSITY;

EID: 84889100399     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.05.007     Document Type: Article

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