Substrate cleavage profiling suggests a distinct function of bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase ii) at the microbiome-inflammation-cancer interface

Journal of Biological Chemistry

Volumn 288, Issue 48, 2013, Pages 34956-34967

  Shiryaev, Sergey A ^a   Remacle, Albert G ^a   Chernov, Andrei V ^a   Golubkov, Vladislav S ^a   Motamedchaboki, Khatereh ^a   Muranaka, Norihito ^b   Dambacher, Corey M ^b   Capek, Petr ^b   Kukreja, Muskan ^b   Kozlov, Igor A ^b   Perucho, Manuel ^a   Cieplak, Piotr ^a   Strongin, Alex Y ^a  

^a BURNHAM INSTITUTE   (United States)

^b Prognosys Biosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTEROIDES FRAGILIS; CLEAVAGE PREFERENCE; COLORECTAL CANCER; METALLOPROTEINASES; PEPTIDE CLEAVAGES; STRUCTURAL EVIDENCE; SUBSTRATE SPECIFICITY; VIRULENCE PROTEINS;

ASSAYS; DISEASES; ENZYME INHIBITION; INTERFACES (MATERIALS); PEPTIDES;

BLOOD VESSELS;

FRAGILYSIN; FRAGILYSIN 3; GELATINASE A; GENOMIC DNA; RECOMBINANT ENZYME; RNA 16S; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; BACTEROIDES FRAGILIS; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; RNA GENE; TUMOR BIOPSY;

EID: 84889077521     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.516153     Document Type: Article

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