A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells

Carcinogenesis

Volumn 34, Issue 12, 2013, Pages 2918-2928

  Yeh, Chi Tai ^a,b,c   Huang, Wen Chien ^d,e   Rao, Yerra Koteswara ^f   Ye, Min ^g   Lee, Wei Hwa ^b   Wang, Liang Shun ^a,b   Tzeng, David T W ^h   Wu, Chih Hsiung ^b   Shieh, Yi Shing ⁱ   Huang, Chi Ying F ^d   Chen, Yu Jen ^d   Hsiao, Michael ^j   Wu, Alexander T H ^a,k   Yang, Zhen ^l   Tzeng, Yew Min ^f  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e MACKAY MEMORIAL HOSPITAL   (Taiwan)

^f CHAOYANG UNIVERSITY OF TECHNOLOGY   (Taiwan)

^g PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^h NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

ⁱ TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^j GENOMICS RESEARCH CENTER   (Taiwan)

^k TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^l PEKING UNIVERSITY   (China)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTROCIN; CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR; INTERLEUKIN 6; JANUS KINASE 2; MICRORNA; MICRORNA LET 7C; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; SESQUITERPENE LACTONE; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTRODIA CAMPHORATA; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; COLONY FORMATION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; INTRACELLULAR SIGNALING; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

AGARICALES; ANTINEOPLASTIC AGENTS; ANTRODIA; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; JANUS KINASE 2; LACTONES; LUNG NEOPLASMS; MICRORNAS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-BCR; SESQUITERPENES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84889008605     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt255     Document Type: Article

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