Arsanilic acid causes apoptosis and oxidative stress in rat kidney epithelial cells (NRK-52e cells) by the activation of the caspase-9 and -3 signaling pathway

Drug and Chemical Toxicology

Volumn 37, Issue 1, 2014, Pages 55-62

  Lu, Yin ^a   Yuan, Hui ^a   Deng, Sijun ^a   Wei, Qiang ^a   Guo, Chengzhi ^a   Yi, Jine ^a   Wu, Jing ^a   Li, Rongfang ^a   Wen, Lixin ^a   He, Zuping ^b   Yuan, Liyun ^a  

^a HUNAN AGRICULTURAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; Arsanilic acid; Caspase 3 and 9; Mitochondria; NRK 52e cells; Reactive oxygen species

Indexed keywords

ARSANILIC ACID; CASPASE 3; CASPASE 9; CASPASE 9 INHIBITOR; DNA NUCLEOTIDYLEXOTRANSFERASE; REACTIVE OXYGEN METABOLITE; TROLOX C;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIUM CELL; FLOW CYTOMETRY; KIDNEY CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SPECTROFLUOROMETRY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; ARSANILIC ACID; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL LINE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPITHELIAL CELLS; KIDNEY; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84888876148     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2013.806532     Document Type: Article

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