메뉴 건너뛰기




Volumn 78, Issue 2, 2012, Pages 330-336

Renal cell carcinoma: Resistance to therapy, role of apoptosis, and the prognostic and therapeutic target potential of TRAF proteins

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BORTEZOMIB; CASPASE 3; CASPASE 8; CISPLATIN; EVEROLIMUS; FLUOROURACIL; GAMMA INTERFERON; GEMCITABINE; INTERLEUKIN 12; INTERLEUKIN 2; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR;

EID: 84855201584     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2011.11.014     Document Type: Article
Times cited : (17)

References (81)
  • 1
    • 0036223636 scopus 로고    scopus 로고
    • Introducing the clusterin gene into human renal cell carcinoma cells enhances their metastatic potential
    • Miyake H., Gleave M.E., Arakawa S., Kamidono S., Hara I. Introducing the clusterin gene into human renal cell carcinoma cells enhances their metastatic potential. J Urol 2002, 167:2203-2208.
    • (2002) J Urol , vol.167 , pp. 2203-2208
    • Miyake, H.1    Gleave, M.E.2    Arakawa, S.3    Kamidono, S.4    Hara, I.5
  • 2
    • 12344335787 scopus 로고    scopus 로고
    • Renal cell carcinoma: review of novel single-agent therapeutics and combination regimens
    • Amato R.J. Renal cell carcinoma: review of novel single-agent therapeutics and combination regimens. Ann Oncol 2005, 16:7-15.
    • (2005) Ann Oncol , vol.16 , pp. 7-15
    • Amato, R.J.1
  • 3
    • 42649145828 scopus 로고    scopus 로고
    • Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review
    • Gupta K., Miller J.D., Li J.Z., Russell M.W., Charbonneau C. Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review. Cancer Treat Rev 2008, 34:193-205.
    • (2008) Cancer Treat Rev , vol.34 , pp. 193-205
    • Gupta, K.1    Miller, J.D.2    Li, J.Z.3    Russell, M.W.4    Charbonneau, C.5
  • 4
    • 0033867195 scopus 로고    scopus 로고
    • Issues in the diagnosis of renal cell carcinoma
    • Nicol D. Issues in the diagnosis of renal cell carcinoma. BJU Int 2000, 86:298-303.
    • (2000) BJU Int , vol.86 , pp. 298-303
    • Nicol, D.1
  • 5
    • 33645345950 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in clear cell renal cell carcinoma by analysis of full-length enriched cDNA library
    • Tang S.W., Chang W.H., Chao Y.W., Lin C.Y., Chen H.F., Lai Y.H., et al. Identification of differentially expressed genes in clear cell renal cell carcinoma by analysis of full-length enriched cDNA library. J Biomed Sci 2006, 13:233-240.
    • (2006) J Biomed Sci , vol.13 , pp. 233-240
    • Tang, S.W.1    Chang, W.H.2    Chao, Y.W.3    Lin, C.Y.4    Chen, H.F.5    Lai, Y.H.6
  • 6
    • 0036168387 scopus 로고    scopus 로고
    • Cellular mechanisms for the repression of apoptosis
    • Bortner C.D., Cidlowski J.A. Cellular mechanisms for the repression of apoptosis. Annu Rev Pharmacol Toxicol 2002, 42:259-281.
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 259-281
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 7
    • 61349098828 scopus 로고    scopus 로고
    • Cryoablation for renal tumors: current status
    • Berger A., Kamoi K., Gill I.S., Aron M. Cryoablation for renal tumors: current status. Curr Opin Urol 2009, 19:138-142.
    • (2009) Curr Opin Urol , vol.19 , pp. 138-142
    • Berger, A.1    Kamoi, K.2    Gill, I.S.3    Aron, M.4
  • 9
    • 0038011500 scopus 로고    scopus 로고
    • Comparative analysis of apoptosis and inflammation genes of mice and humans
    • Reed J.C., Doctor K., Rojas A., Zapata J.M., Stehlik C., Fiorentino L., et al. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res 2003, 13:1376-1388.
    • (2003) Genome Res , vol.13 , pp. 1376-1388
    • Reed, J.C.1    Doctor, K.2    Rojas, A.3    Zapata, J.M.4    Stehlik, C.5    Fiorentino, L.6
  • 10
    • 79954444032 scopus 로고    scopus 로고
    • Roles of the TNF family in normal development and cancer
    • doi:10.1007/978-1-4419-6612-4_1
    • N.H. Ruddle, Roles of the TNF family in normal development and cancer, Adv Exp Med Biol 2011. DOI doi:10.1007/978-1-4419-6612-4_1.
    • (2011) Adv Exp Med Biol
    • Ruddle, N.H.1
  • 11
    • 38949119408 scopus 로고    scopus 로고
    • Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity
    • Hughes P.D., Belz G.T., Fortner K.A., Budd R.C., Strasser A., Bouillet P. Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity 2008, 28:197-205.
    • (2008) Immunity , vol.28 , pp. 197-205
    • Hughes, P.D.1    Belz, G.T.2    Fortner, K.A.3    Budd, R.C.4    Strasser, A.5    Bouillet, P.6
  • 14
    • 9344245131 scopus 로고    scopus 로고
    • TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice
    • Zapata J.M., Krajewska M., Morse H.C., Choi Y., Reed J.C. TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice. Proc Natl Acad Sci USA 2004, 101:16600-16605.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16600-16605
    • Zapata, J.M.1    Krajewska, M.2    Morse, H.C.3    Choi, Y.4    Reed, J.C.5
  • 15
    • 0038717240 scopus 로고    scopus 로고
    • TNF-receptor-associated factors as targets for drug development
    • Zapata J.M. TNF-receptor-associated factors as targets for drug development. Expert Opin Ther Targets 2003, 7(7):411-425.
    • (2003) Expert Opin Ther Targets , vol.7 , Issue.7 , pp. 411-425
    • Zapata, J.M.1
  • 16
    • 35648936526 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose
    • Harrison M.L., Obermueller E., Maisey N.R., Hoare S., Edmonds K., Li N.F., et al. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose. J Clin Oncol 2007, 25:4542-4549.
    • (2007) J Clin Oncol , vol.25 , pp. 4542-4549
    • Harrison, M.L.1    Obermueller, E.2    Maisey, N.R.3    Hoare, S.4    Edmonds, K.5    Li, N.F.6
  • 17
    • 3543079892 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases
    • Xanthoulea S., Pasparakis M., Kousteni S., Brakebusch C., Wallach D., Bauer J., et al. Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases. J Exp Med 2004, 200:367-376.
    • (2004) J Exp Med , vol.200 , pp. 367-376
    • Xanthoulea, S.1    Pasparakis, M.2    Kousteni, S.3    Brakebusch, C.4    Wallach, D.5    Bauer, J.6
  • 18
    • 0034752285 scopus 로고    scopus 로고
    • TRAF1 is a negative regulator of TNF signaling. Enhanced TNF signaling in TRAF1-deficient mice
    • Tsitsikov E.N., Laouini D., Dunn I.F., Sannikova T.Y., Davidson L., Alt F.W., et al. TRAF1 is a negative regulator of TNF signaling. Enhanced TNF signaling in TRAF1-deficient mice. Immunity 2001, 15:647-657.
    • (2001) Immunity , vol.15 , pp. 647-657
    • Tsitsikov, E.N.1    Laouini, D.2    Dunn, I.F.3    Sannikova, T.Y.4    Davidson, L.5    Alt, F.W.6
  • 19
    • 0035475338 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factors (TRAFs)
    • Bradley J.R., Pober J.S. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 2001, 20:6482-6491.
    • (2001) Oncogene , vol.20 , pp. 6482-6491
    • Bradley, J.R.1    Pober, J.S.2
  • 20
  • 22
    • 25144503984 scopus 로고    scopus 로고
    • Somatic VHL alteration and its impact on prognosis in patients with clear cell renal cell carcinoma
    • Kim J.H., Jung C.W., Cho Y.H., Lee J., Lee S.H., Kim H.Y., et al. Somatic VHL alteration and its impact on prognosis in patients with clear cell renal cell carcinoma. Oncol Rep 2005, 13:859-864.
    • (2005) Oncol Rep , vol.13 , pp. 859-864
    • Kim, J.H.1    Jung, C.W.2    Cho, Y.H.3    Lee, J.4    Lee, S.H.5    Kim, H.Y.6
  • 23
    • 45249124315 scopus 로고    scopus 로고
    • Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor
    • Nyhan M.H., O'Sullivan G.C., McKenna S.L. Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor. Biochem Soc Trans 2008, 36:472-478.
    • (2008) Biochem Soc Trans , vol.36 , pp. 472-478
    • Nyhan, M.H.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 24
    • 3042609752 scopus 로고    scopus 로고
    • Pathological and molecular biological aspects of the renal epithelial neoplasms, up-to-date
    • Nagashima Y., Inayama Y., Kato Y., Sakai N., Kanno H., Aoki I., et al. Pathological and molecular biological aspects of the renal epithelial neoplasms, up-to-date. Pathol Int 2004, 54:377-386.
    • (2004) Pathol Int , vol.54 , pp. 377-386
    • Nagashima, Y.1    Inayama, Y.2    Kato, Y.3    Sakai, N.4    Kanno, H.5    Aoki, I.6
  • 25
    • 2142853538 scopus 로고    scopus 로고
    • Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma
    • Beck S.D., Patel M.I., Snyder M.E., Kattan M.J., Motzer R.J., Reuter V.E., et al. Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma. Ann Surg Oncol 2004, 11:71-77.
    • (2004) Ann Surg Oncol , vol.11 , pp. 71-77
    • Beck, S.D.1    Patel, M.I.2    Snyder, M.E.3    Kattan, M.J.4    Motzer, R.J.5    Reuter, V.E.6
  • 26
    • 0642276400 scopus 로고    scopus 로고
    • Gene expression profiling of renal cell carcinoma and its implications in diagnosis, prognosis, and therapeutics
    • Takahashi M., Sugimura J., Yang X., Vogelzang N., The B.S., Furge K., et al. Gene expression profiling of renal cell carcinoma and its implications in diagnosis, prognosis, and therapeutics. Adv Cancer Res 2003, 89:157-181.
    • (2003) Adv Cancer Res , vol.89 , pp. 157-181
    • Takahashi, M.1    Sugimura, J.2    Yang, X.3    Vogelzang, N.4    The, B.S.5    Furge, K.6
  • 27
    • 33645216355 scopus 로고    scopus 로고
    • Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia
    • Tickoo S.K., dePeralta-Venturina M.N., Harik L.R., Worcester H.D., Salama M.E., Young A.N. Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol 2006, 30:141-153.
    • (2006) Am J Surg Pathol , vol.30 , pp. 141-153
    • Tickoo, S.K.1    dePeralta-Venturina, M.N.2    Harik, L.R.3    Worcester, H.D.4    Salama, M.E.5    Young, A.N.6
  • 30
    • 0242521464 scopus 로고    scopus 로고
    • Molecular subclassification of kidney tumors and the discovery of new diagnostic markers
    • Takahashi M., Yang X.M.J., Sugimura J., Backdahl J., Tretiakova M., Qian C.N., et al. Molecular subclassification of kidney tumors and the discovery of new diagnostic markers. Oncogene 2003, 22:6810-6818.
    • (2003) Oncogene , vol.22 , pp. 6810-6818
    • Takahashi, M.1    Yang, X.M.J.2    Sugimura, J.3    Backdahl, J.4    Tretiakova, M.5    Qian, C.N.6
  • 31
    • 0036716923 scopus 로고    scopus 로고
    • Unclassified renal cell carcinoma: clinical features and prognostic impact of a new histological subtype
    • Zisman A., Chao D.H., Pantuck A.J., Kim H.J., Wieder J.A., Figlin R.A., et al. Unclassified renal cell carcinoma: clinical features and prognostic impact of a new histological subtype. J Urol 2002, 168:950-955.
    • (2002) J Urol , vol.168 , pp. 950-955
    • Zisman, A.1    Chao, D.H.2    Pantuck, A.J.3    Kim, H.J.4    Wieder, J.A.5    Figlin, R.A.6
  • 32
    • 0033014968 scopus 로고    scopus 로고
    • Sarcomatoid renal cell carcinoma: Biologic behavious, prognosis, and response to combined surgical resection and immunotherapy
    • Cangiano T., Liao J., Dorey F., Figlin R., Belldegrun A. Sarcomatoid renal cell carcinoma: Biologic behavious, prognosis, and response to combined surgical resection and immunotherapy. J Clin Oncol 1999, 17:523-528.
    • (1999) J Clin Oncol , vol.17 , pp. 523-528
    • Cangiano, T.1    Liao, J.2    Dorey, F.3    Figlin, R.4    Belldegrun, A.5
  • 33
    • 18844478027 scopus 로고    scopus 로고
    • Renal cell carcinoma, chromophobe type, with collecting duct carcinoma and sarcomatoid components
    • Gong Y., Sun X., Haines G.K., Pins M.R. Renal cell carcinoma, chromophobe type, with collecting duct carcinoma and sarcomatoid components. Arch Pathol Lab Med 2003, 127:e38-e40.
    • (2003) Arch Pathol Lab Med , vol.127
    • Gong, Y.1    Sun, X.2    Haines, G.K.3    Pins, M.R.4
  • 34
    • 0036281244 scopus 로고    scopus 로고
    • Cytokeratin 7: a useful adjunct in the diagnosis of chromophobe renal cell carcinoma
    • Mathers M.E., Pollock A.M., Marsh C., O'Donnell M. Cytokeratin 7: a useful adjunct in the diagnosis of chromophobe renal cell carcinoma. Histopathology 2002, 49:563-567.
    • (2002) Histopathology , vol.49 , pp. 563-567
    • Mathers, M.E.1    Pollock, A.M.2    Marsh, C.3    O'Donnell, M.4
  • 35
    • 0031022173 scopus 로고    scopus 로고
    • Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases
    • Amin M.B., Crotty T.B., Tickoo S.K., Farrow G.M. Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases. Am J Surg Pathol 1997, 21:1-12.
    • (1997) Am J Surg Pathol , vol.21 , pp. 1-12
    • Amin, M.B.1    Crotty, T.B.2    Tickoo, S.K.3    Farrow, G.M.4
  • 36
    • 33847649218 scopus 로고    scopus 로고
    • Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: A potential mechanism of apoptosis resistance
    • Lin P.Y., Fosmire S.P., Park J.Y., Baksh S., Modiano J.F., Weiss R.H. Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: A potential mechanism of apoptosis resistance. Mol Cancer 2007, 6:16-27.
    • (2007) Mol Cancer , vol.6 , pp. 16-27
    • Lin, P.Y.1    Fosmire, S.P.2    Park, J.Y.3    Baksh, S.4    Modiano, J.F.5    Weiss, R.H.6
  • 37
    • 72949106926 scopus 로고    scopus 로고
    • Increased activated Akt expression in renal cell carcinomas and prognosis
    • Hager M., Haufe H., Kemmerling R., Hitzl W., Mikuz G., Moser P.L., et al. Increased activated Akt expression in renal cell carcinomas and prognosis. J Cell Mol Med 2009, 11:2181-2188.
    • (2009) J Cell Mol Med , vol.11 , pp. 2181-2188
    • Hager, M.1    Haufe, H.2    Kemmerling, R.3    Hitzl, W.4    Mikuz, G.5    Moser, P.L.6
  • 39
    • 70349385645 scopus 로고    scopus 로고
    • Resistance to targeted therapy in renal-cell carcinoma
    • Rini B., Atkins M.B. Resistance to targeted therapy in renal-cell carcinoma. Lancet Oncol 2009, 10:992-1000.
    • (2009) Lancet Oncol , vol.10 , pp. 992-1000
    • Rini, B.1    Atkins, M.B.2
  • 41
    • 0033565728 scopus 로고    scopus 로고
    • Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells
    • Lucci A., Han T.Y., Liu Y.Y., Giuliano A.E., Cabot M.C. Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells. Cancer 1999, 86:300-311.
    • (1999) Cancer , vol.86 , pp. 300-311
    • Lucci, A.1    Han, T.Y.2    Liu, Y.Y.3    Giuliano, A.E.4    Cabot, M.C.5
  • 42
    • 54849186300 scopus 로고    scopus 로고
    • Significant antitumor activity of cationic multilamellar liposomes containing human interferon-beta gene in combination with 5-fluorouracil against human renal cell carcinoma
    • Yamamoto K., Mizutani Y., Nakanishi H., Fujiwara J., Ishida H., Toiyama D., et al. Significant antitumor activity of cationic multilamellar liposomes containing human interferon-beta gene in combination with 5-fluorouracil against human renal cell carcinoma. Int J Oncol 2008, 33:565-571.
    • (2008) Int J Oncol , vol.33 , pp. 565-571
    • Yamamoto, K.1    Mizutani, Y.2    Nakanishi, H.3    Fujiwara, J.4    Ishida, H.5    Toiyama, D.6
  • 44
    • 0020656561 scopus 로고
    • The role of radiation therapy in the management of metastatic renal cell carcinoma
    • Halperin E.C., Harisiadis L. The role of radiation therapy in the management of metastatic renal cell carcinoma. Cancer 1983, 51:614-617.
    • (1983) Cancer , vol.51 , pp. 614-617
    • Halperin, E.C.1    Harisiadis, L.2
  • 45
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano H., Carney D., Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Updat 2004, 7:97-110.
    • (2004) Drug Resist Updat , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 46
    • 0036138282 scopus 로고    scopus 로고
    • Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil
    • Mizutani Y., Nakanishi H., Yoshida O., Fukushima M., Bonavida B., Miki T. Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil. Eur J Cancer 2002, 38:167-176.
    • (2002) Eur J Cancer , vol.38 , pp. 167-176
    • Mizutani, Y.1    Nakanishi, H.2    Yoshida, O.3    Fukushima, M.4    Bonavida, B.5    Miki, T.6
  • 47
    • 0036307780 scopus 로고    scopus 로고
    • Rituximab modifies the cisplatin-mitochondrial signaling pathway, resulting in apoptosis in cisplatin-resistant non-Hodgkin's lymphoma
    • Alas S., Ng C.P., Bonavida B. Rituximab modifies the cisplatin-mitochondrial signaling pathway, resulting in apoptosis in cisplatin-resistant non-Hodgkin's lymphoma. Clin Cancer Res 2002, 8:836-845.
    • (2002) Clin Cancer Res , vol.8 , pp. 836-845
    • Alas, S.1    Ng, C.P.2    Bonavida, B.3
  • 48
    • 0034431510 scopus 로고    scopus 로고
    • Inhibition of lung metastases of murine renal cell carcinoma by the combination of radiation and interferon-alpha-producing tumor cell vaccine
    • Nishisaka N., Jones R.F., Morse P., Kuratsukuri K., Romanowski R., Wang C.Y., et al. Inhibition of lung metastases of murine renal cell carcinoma by the combination of radiation and interferon-alpha-producing tumor cell vaccine. Cytokines Cell Mol Ther 2000, 6:199-206.
    • (2000) Cytokines Cell Mol Ther , vol.6 , pp. 199-206
    • Nishisaka, N.1    Jones, R.F.2    Morse, P.3    Kuratsukuri, K.4    Romanowski, R.5    Wang, C.Y.6
  • 49
    • 79957504870 scopus 로고    scopus 로고
    • Sequential therapies with sorafenib and sunitinib in advanced or metastatic renal cell carcinoma
    • [Epub ahead of print].
    • E. Herrmann, N. Marschner, M.O. Grimm, C.H. Ohlmann, H. Hutzschenreuter and F. Overkamp et al., Sequential therapies with sorafenib and sunitinib in advanced or metastatic renal cell carcinoma, World J Urol 2011; [Epub ahead of print].
    • (2011) World J Urol
    • Herrmann, E.1    Marschner, N.2    Grimm, M.O.3    Ohlmann, C.H.4    Hutzschenreuter, H.5    Overkamp, F.6
  • 51
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams J.M., Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007, 26:1324-1337.
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 52
    • 0034284637 scopus 로고    scopus 로고
    • Mitochondria as the central control point of apoptosis
    • Desagher S., Martinou J.C. Mitochondria as the central control point of apoptosis. Trends Cell Biol 2000, 10:369-377.
    • (2000) Trends Cell Biol , vol.10 , pp. 369-377
    • Desagher, S.1    Martinou, J.C.2
  • 53
    • 0033936787 scopus 로고    scopus 로고
    • Bax, Bid and the permeabilization of the mitochondrial outer membrane in apoptosis
    • Crompton M. Bax, Bid and the permeabilization of the mitochondrial outer membrane in apoptosis. Curr Opin Cell Biol 2000, 12:414-419.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 414-419
    • Crompton, M.1
  • 54
    • 0037946767 scopus 로고    scopus 로고
    • Messengers of cell death: apoptotic signaling in health and disease
    • Rossi D., Gaidano G. Messengers of cell death: apoptotic signaling in health and disease. Haematologica 2003, 88:212-218.
    • (2003) Haematologica , vol.88 , pp. 212-218
    • Rossi, D.1    Gaidano, G.2
  • 55
    • 16644394363 scopus 로고    scopus 로고
    • Caspases: potential targets for regulating cell death
    • Philchenkov A. Caspases: potential targets for regulating cell death. J Cell Mol Med 2004, 8:432-444.
    • (2004) J Cell Mol Med , vol.8 , pp. 432-444
    • Philchenkov, A.1
  • 56
    • 77952944929 scopus 로고    scopus 로고
    • Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex
    • Brooks A.D., Jacobsen K., Li W., Shanker A., Sayers T.J. Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex. Mol Cancer Res 2010, 8:729-738.
    • (2010) Mol Cancer Res , vol.8 , pp. 729-738
    • Brooks, A.D.1    Jacobsen, K.2    Li, W.3    Shanker, A.4    Sayers, T.J.5
  • 57
    • 0032101601 scopus 로고    scopus 로고
    • P53, bcl-2, And Bax expression in renal cell carcinoma
    • Vasavada S.P., Novick A.C., Williams B.R. P53, bcl-2, And Bax expression in renal cell carcinoma. Urology 1998, 51:1057-1061.
    • (1998) Urology , vol.51 , pp. 1057-1061
    • Vasavada, S.P.1    Novick, A.C.2    Williams, B.R.3
  • 58
    • 0036251711 scopus 로고    scopus 로고
    • Apoptosis and expression of Bcl-2, Bcl-XL, and Bax in renal cell carcinomas
    • Gobe G., Rubin M., Williams G., Sawczuk I., Buttyan R. Apoptosis and expression of Bcl-2, Bcl-XL, and Bax in renal cell carcinomas. Cancer Invest 2002, 20:324-332.
    • (2002) Cancer Invest , vol.20 , pp. 324-332
    • Gobe, G.1    Rubin, M.2    Williams, G.3    Sawczuk, I.4    Buttyan, R.5
  • 59
    • 0035409326 scopus 로고    scopus 로고
    • Activation of caspase-3 in renal cell carcinoma cells by anthracyclines or 5-fluorouracil
    • Wu X.X., Kakehi Y., Mizutani Y., Lu J., Terachi T., Ogawa O. Activation of caspase-3 in renal cell carcinoma cells by anthracyclines or 5-fluorouracil. Int J Oncol 2001, 19:19-24.
    • (2001) Int J Oncol , vol.19 , pp. 19-24
    • Wu, X.X.1    Kakehi, Y.2    Mizutani, Y.3    Lu, J.4    Terachi, T.5    Ogawa, O.6
  • 60
    • 33645774449 scopus 로고    scopus 로고
    • Comparative analysis of caspase activation and apoptosis in renal tubular epithelial cells and renal cell carcinomas
    • Davidson K., Percy C., Rennick A.J., Pat B.K., Li J., Nicol D., et al. Comparative analysis of caspase activation and apoptosis in renal tubular epithelial cells and renal cell carcinomas. Nephron Exp Nephrol 2005, 99:112-120.
    • (2005) Nephron Exp Nephrol , vol.99 , pp. 112-120
    • Davidson, K.1    Percy, C.2    Rennick, A.J.3    Pat, B.K.4    Li, J.5    Nicol, D.6
  • 61
    • 0037084504 scopus 로고    scopus 로고
    • All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction
    • Chung J.Y., Park Y.C., Ye H., Wu H. All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J Cell Sci 2002, 115:679-688.
    • (2002) J Cell Sci , vol.115 , pp. 679-688
    • Chung, J.Y.1    Park, Y.C.2    Ye, H.3    Wu, H.4
  • 62
    • 0034697172 scopus 로고    scopus 로고
    • The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity
    • Zapata J.M., Matsuzawa S., Godzik A., Leo E., Wasserman S.A., Reed J.C. The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity. J Biol Chem 2000, 275:12102-12107.
    • (2000) J Biol Chem , vol.275 , pp. 12102-12107
    • Zapata, J.M.1    Matsuzawa, S.2    Godzik, A.3    Leo, E.4    Wasserman, S.A.5    Reed, J.C.6
  • 63
    • 0034803045 scopus 로고    scopus 로고
    • Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death
    • Jang H.D., Chung Y.M., Baik J.H., Choi Y.G., Park I.S., Jung Y.K. Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death. Biochem Biophys Res Commun 2001, 281:499-505.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 499-505
    • Jang, H.D.1    Chung, Y.M.2    Baik, J.H.3    Choi, Y.G.4    Park, I.S.5    Jung, Y.K.6
  • 64
    • 34547138171 scopus 로고    scopus 로고
    • NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis
    • Zhang B., Wang Z., Li T., Tsitsikov E.N., Ding H.F. NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis. Blood 2007, 110:743-751.70.
    • (2007) Blood , vol.110
    • Zhang, B.1    Wang, Z.2    Li, T.3    Tsitsikov, E.N.4    Ding, H.F.5
  • 65
    • 1842482350 scopus 로고    scopus 로고
    • Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway
    • Wang X., Wang Q., Hu W., Evers B.M. Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway. Oncogene 2004, 23:1885-1895.
    • (2004) Oncogene , vol.23 , pp. 1885-1895
    • Wang, X.1    Wang, Q.2    Hu, W.3    Evers, B.M.4
  • 66
    • 58249115041 scopus 로고    scopus 로고
    • TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis
    • Blackwell K., Zhang L., Thomas G.S., Sun H., Nakano H., Habelhah H. TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis. Mol Cell Biol 2009, 29:303-314.
    • (2009) Mol Cell Biol , vol.29 , pp. 303-314
    • Blackwell, K.1    Zhang, L.2    Thomas, G.S.3    Sun, H.4    Nakano, H.5    Habelhah, H.6
  • 67
    • 77949332322 scopus 로고    scopus 로고
    • The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB
    • Zhang L., Blackwell K., Shi Z., Habelhah H. The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB. J Mol Biol 2010, 396:528-539.
    • (2010) J Mol Biol , vol.396 , pp. 528-539
    • Zhang, L.1    Blackwell, K.2    Shi, Z.3    Habelhah, H.4
  • 68
    • 80053357273 scopus 로고    scopus 로고
    • The emerging role of nuclear factor kappa B in renal cell carcinoma
    • Morais C., Gobe G., Johnson D.W., Healy H.H. The emerging role of nuclear factor kappa B in renal cell carcinoma. Int J Biochem Cell Biol 2011, 43:1537-1549.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1537-1549
    • Morais, C.1    Gobe, G.2    Johnson, D.W.3    Healy, H.H.4
  • 69
    • 77951695765 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappa B attenuates tumour progression in an animal model of renal cell carcinoma
    • Morais C., Healy H., Johnson D.W., Gobe G. Inhibition of nuclear factor kappa B attenuates tumour progression in an animal model of renal cell carcinoma. Nephrol Dial Transplant 2010, 25:1462-1474.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1462-1474
    • Morais, C.1    Healy, H.2    Johnson, D.W.3    Gobe, G.4
  • 70
    • 63849131615 scopus 로고    scopus 로고
    • Expression of apoptotic tumour necrosis factor receptor-associated factor, caspase recruitment domain and cell death-inducing DFF-45 effector genes in therapy-treated renal cell carcinoma
    • Rajandram R., Pat B.K., Li J., Johnson D.W., Gobe G.C. Expression of apoptotic tumour necrosis factor receptor-associated factor, caspase recruitment domain and cell death-inducing DFF-45 effector genes in therapy-treated renal cell carcinoma. Nephrology (Carlton) 2009, 14:205-212.
    • (2009) Nephrology (Carlton) , vol.14 , pp. 205-212
    • Rajandram, R.1    Pat, B.K.2    Li, J.3    Johnson, D.W.4    Gobe, G.C.5
  • 71
    • 62449168519 scopus 로고    scopus 로고
    • TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges
    • Bellail A.C., Qi L., Mulligan P., Chhabra V., Hao C. TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev Recent Clin Trials 2009, 4:34-41.
    • (2009) Rev Recent Clin Trials , vol.4 , pp. 34-41
    • Bellail, A.C.1    Qi, L.2    Mulligan, P.3    Chhabra, V.4    Hao, C.5
  • 72
    • 79960913158 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis signaling pathway for cancer therapy
    • Sayers T.J. Targeting the extrinsic apoptosis signaling pathway for cancer therapy. Cancer Immunol Immunother 2011, 60:1173-1180.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1173-1180
    • Sayers, T.J.1
  • 74
    • 52649109068 scopus 로고    scopus 로고
    • The TRAIL apoptotic pathway in cancer onset, Progression and therapy
    • Johnstone R.W., Frew A.J., Smyth M.J. The TRAIL apoptotic pathway in cancer onset, Progression and therapy. Nat Rev Cancer 2008, 8:782-798.
    • (2008) Nat Rev Cancer , vol.8 , pp. 782-798
    • Johnstone, R.W.1    Frew, A.J.2    Smyth, M.J.3
  • 75
    • 2642677624 scopus 로고    scopus 로고
    • Improving protein therapeutics with sustained-release formulations
    • Putney S.D., Burke P.A. Improving protein therapeutics with sustained-release formulations. Nature Biotechnol 1998, 16:153-157.
    • (1998) Nature Biotechnol , vol.16 , pp. 153-157
    • Putney, S.D.1    Burke, P.A.2
  • 76
    • 78650009505 scopus 로고    scopus 로고
    • Biological activities of natural and engineered cyclotides, a novel molecular for peptide-based therapies
    • Garcia A.E., Camarero J.A. Biological activities of natural and engineered cyclotides, a novel molecular for peptide-based therapies. Curr Mol Pharmacol 2010, 3:153-163.
    • (2010) Curr Mol Pharmacol , vol.3 , pp. 153-163
    • Garcia, A.E.1    Camarero, J.A.2
  • 77
    • 14544270950 scopus 로고    scopus 로고
    • Predictive markers in breast and other cancers: a review
    • Duffy M.J. Predictive markers in breast and other cancers: a review. Clin Chem 2005, 51:494-503.
    • (2005) Clin Chem , vol.51 , pp. 494-503
    • Duffy, M.J.1
  • 79
    • 77953914799 scopus 로고    scopus 로고
    • Current management of advanced and metastatic renal cell carcinoma
    • Ather M.H., Masood N., Siddiqui T. Current management of advanced and metastatic renal cell carcinoma. Urol J 2010, 7:1-9.
    • (2010) Urol J , vol.7 , pp. 1-9
    • Ather, M.H.1    Masood, N.2    Siddiqui, T.3
  • 80
    • 77954270234 scopus 로고    scopus 로고
    • Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models
    • Vermaat J.S., van der Tweel I., Mehra N., Sleijfer S., Haanen J.B., Roodhart J.M., et al. Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models. Ann Oncol 2010, 21:1472-1481.
    • (2010) Ann Oncol , vol.21 , pp. 1472-1481
    • Vermaat, J.S.1    van der Tweel, I.2    Mehra, N.3    Sleijfer, S.4    Haanen, J.B.5    Roodhart, J.M.6
  • 81
    • 78751693800 scopus 로고    scopus 로고
    • Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets
    • Swanton C., Larkin J.M., Gerlinger M., Eklund A.C., Howell M., Stamp G., et al. Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets. Genome Med 2010, 2:53.
    • (2010) Genome Med , vol.2 , pp. 53
    • Swanton, C.1    Larkin, J.M.2    Gerlinger, M.3    Eklund, A.C.4    Howell, M.5    Stamp, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.