Modulation of multidrug resistance in cancer cells by chelidonine and Chelidonium majus alkaloids

Phytomedicine

Volumn 20, Issue 3-4, 2013, Pages 282-294

  El Readi, Mahmoud Zaki ^a,b   Eid, Safaayehia ^a   Ashour, Mohamed Lotfy ^a,c   Tahrani, Ahmad ^a   Wink, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Al Azhar University   (Egypt)

^c Ain Shams University   (Egypt)

Author keywords

Apoptosis; Chelidonine; Chelidonium majus; Gene expression profiling; Metabolic enzymes; Multidrug resistance

Indexed keywords

ABC TRANSPORTER; BENZO[C]PHENANTHRIDINE DERIVATIVE; BREAST CANCER RESISTANCE PROTEIN; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE 9; CHELIDONINE; CHELIDONIUM EXTRACT; COMPLEMENTARY DNA; CYTOCHROME P450 3A4; DOXORUBICIN; GLUTATHIONE TRANSFERASE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHATIDYLSERINE; PROTOBERBERINE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL CYCLE; CHELIDONIUM; CONTROLLED STUDY; CYTOTOXICITY; DRUG METABOLISM; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ALKALOIDS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; BENZOPHENANTHRIDINES; CASPASES; CELL LINE, TUMOR; CHELIDONIUM; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP3A; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; GLUTATHIONE TRANSFERASE; HUMANS; MASS SPECTROMETRY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLANT EXTRACTS; REAL-TIME POLYMERASE CHAIN REACTION;

ANIMALIA; CHELIDONIUM MAJUS;

EID: 84873710000     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.11.005     Document Type: Article

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