-
1
-
-
33645224029
-
The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure
-
C. Bachran, M. Sutherland, I. Heisler, P. Hebestreit, M.F. Melzig, and H. Fuchs The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure Experimental Biology and Medicine (Maywood, NJ) 231 2006 412 420
-
(2006)
Experimental Biology and Medicine (Maywood, NJ)
, vol.231
, pp. 412-420
-
-
Bachran, C.1
Sutherland, M.2
Heisler, I.3
Hebestreit, P.4
Melzig, M.F.5
Fuchs, H.6
-
3
-
-
0017843255
-
A method for testing for synergy with any number of agents
-
M.C. Berenbaum A method for testing for synergy with any number of agents Journal of Infectious Diseases 137 1978 122 130
-
(1978)
Journal of Infectious Diseases
, vol.137
, pp. 122-130
-
-
Berenbaum, M.C.1
-
6
-
-
0029997940
-
Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells
-
M.E. Cavet, M. West, and N.L. Simmons Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells British Journal of Pharmacology 118 1996 1389 1396
-
(1996)
British Journal of Pharmacology
, vol.118
, pp. 1389-1396
-
-
Cavet, M.E.1
West, M.2
Simmons, N.L.3
-
7
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
T.C. Chou, and P. Talalay Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors Advances in Enzyme Regulation 22 1984 27 55
-
(1984)
Advances in Enzyme Regulation
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
8
-
-
33748794547
-
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
-
T.C. Chou Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies Pharmacological Reviews 58 2006 621 681
-
(2006)
Pharmacological Reviews
, vol.58
, pp. 621-681
-
-
Chou, T.C.1
-
9
-
-
76549129820
-
Drug combination studies and their synergy quantification using the Chou-Talalay method
-
T.C. Chou Drug combination studies and their synergy quantification using the Chou-Talalay method Cancer Research 70 2010 440 446
-
(2010)
Cancer Research
, vol.70
, pp. 440-446
-
-
Chou, T.C.1
-
10
-
-
0027102401
-
The MDR1 gene product P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin
-
I.A. de Lannoy, and M. Silverman The MDR1 gene product P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin Biochemical and Biophysical Research Communications 189 1992 551 557
-
(1992)
Biochemical and Biophysical Research Communications
, vol.189
, pp. 551-557
-
-
De Lannoy, I.A.1
Silverman, M.2
-
11
-
-
33750254749
-
Synergism of CAY-1 with amphotericin B and itraconazole
-
A.J. De Lucca, J.M. Bland, S. Boue, C.B. Vigo, T.E. Cleveland, and T.J. Walsh Synergism of CAY-1 with amphotericin B and itraconazole Chemotherapy 52 2006 285 287
-
(2006)
Chemotherapy
, vol.52
, pp. 285-287
-
-
De Lucca, A.J.1
Bland, J.M.2
Boue, S.3
Vigo, C.B.4
Cleveland, T.E.5
Walsh, T.J.6
-
12
-
-
84865222831
-
Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transporters
-
S.Y. Eid, M.Z. El-Readi, and M. Wink Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transporters Phytomedicine 19 2012 977 987
-
(2012)
Phytomedicine
, vol.19
, pp. 977-987
-
-
Eid, S.Y.1
El-Readi, M.Z.2
Wink, M.3
-
13
-
-
84870053873
-
Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells
-
doi:10.1016/j.phymed.2012.08.010 in press.
-
Eid, S.Y.; El-Readi, M.Z.; Wink, M. Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells. Phytomedicine, http://dx.doi.org/10.1016/j.phymed.2012.08.010, in press.
-
Phytomedicine
-
-
Eid, S.Y.1
El-Readi, M.Z.2
Wink, M.3
-
14
-
-
70649091119
-
Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines
-
M.Z. El-Readi, D. Hamdan, N. Farrag, A. El-Shazly, and M. Wink Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines European Journal of Pharmacology 626 2010 139 145
-
(2010)
European Journal of Pharmacology
, vol.626
, pp. 139-145
-
-
El-Readi, M.Z.1
Hamdan, D.2
Farrag, N.3
El-Shazly, A.4
Wink, M.5
-
16
-
-
0035826692
-
Avicins: Triterpenoid saponins from Acacia victoriae (Bentham) induce apoptosis by mitochondrial perturbation
-
V. Haridas, M. Higuchi, G.S. Jayatilake, D. Bailey, K. Mujoo, M.E. Blake, C.J. Arntzen, and J.U. Gutterman Avicins: triterpenoid saponins from Acacia victoriae (Bentham) induce apoptosis by mitochondrial perturbation Proceedings of the National Academy of Sciences of the United States of America 98 2001 5821 5826
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, pp. 5821-5826
-
-
Haridas, V.1
Higuchi, M.2
Jayatilake, G.S.3
Bailey, D.4
Mujoo, K.5
Blake, M.E.6
Arntzen, C.J.7
Gutterman, J.U.8
-
17
-
-
0346216104
-
Cytotoxic activity of the seeds from Agrostemma githago var. githago
-
P. Hebestreit, and M.F. Melzig Cytotoxic activity of the seeds from Agrostemma githago var. githago Planta Medica 69 2003 921 925
-
(2003)
Planta Medica
, vol.69
, pp. 921-925
-
-
Hebestreit, P.1
Melzig, M.F.2
-
19
-
-
80053910812
-
Synergistic interactions of saponins and monoterpenes in HeLa cells Cos7 cells and in erythrocytes
-
F. Herrmann, and M. Wink Synergistic interactions of saponins and monoterpenes in HeLa cells Cos7 cells and in erythrocytes Phytomedicine 18 2011 1191 1196
-
(2011)
Phytomedicine
, vol.18
, pp. 1191-1196
-
-
Herrmann, F.1
Wink, M.2
-
20
-
-
72249117808
-
P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir
-
O. Janneh, T. Anwar, C. Jungbauer, S. Kopp, S.H. Khoo, D.J. Back, and P. Chiba P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir Antiviral Therapy 14 2009 965 974
-
(2009)
Antiviral Therapy
, vol.14
, pp. 965-974
-
-
Janneh, O.1
Anwar, T.2
Jungbauer, C.3
Kopp, S.4
Khoo, S.H.5
Back, D.J.6
Chiba, P.7
-
22
-
-
76549121864
-
Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB
-
S.M. Kim, S.Y. Lee, J.S. Cho, S.M. Son, S.S. Choi, Y.P. Yun, H.S. Yoo, Y. Yoon do, K.W. Oh, S.B. Han, and J.T. Hong Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB European Journal of Pharmacology 631 2010 1 9
-
(2010)
European Journal of Pharmacology
, vol.631
, pp. 1-9
-
-
Kim, S.M.1
Lee, S.Y.2
Cho, J.S.3
Son, S.M.4
Choi, S.S.5
Yun, Y.P.6
Yoo, H.S.7
Yoon Do, Y.8
Oh, K.W.9
Han, S.B.10
Hong, J.T.11
-
23
-
-
48649092518
-
Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells
-
Y. Ma, and M. Wink Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells Phytomedicine 15 2008 754 758
-
(2008)
Phytomedicine
, vol.15
, pp. 754-758
-
-
Ma, Y.1
Wink, M.2
-
25
-
-
29144444375
-
Structure-activity relationship of saponins to enhance toxic effects of agrostin
-
M.F. Melzig, P. Hebestreit, G. Gaidi, and M.A. Lacaille-Dubois Structure-activity relationship of saponins to enhance toxic effects of agrostin Planta Medica 71 2005 1088 1090
-
(2005)
Planta Medica
, vol.71
, pp. 1088-1090
-
-
Melzig, M.F.1
Hebestreit, P.2
Gaidi, G.3
Lacaille-Dubois, M.A.4
-
26
-
-
38449118392
-
The alkaloid emetine as a promising agent for the induction and enhancement of drug-induced apoptosis in leukemia cells
-
M. Möller, K. Herzer, T. Wenger, I. Herr, and M. Wink The alkaloid emetine as a promising agent for the induction and enhancement of drug-induced apoptosis in leukemia cells Oncology Reports 18 2007 737 744
-
(2007)
Oncology Reports
, vol.18
, pp. 737-744
-
-
Möller, M.1
Herzer, K.2
Wenger, T.3
Herr, I.4
Wink, M.5
-
27
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays Journal of Immunological Methods 65 1983 55 63
-
(1983)
Journal of Immunological Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
28
-
-
0033869333
-
Treatment of poor-prognosis early rheumatoid arthritis. A randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone
-
S.M. Proudman, P.G. Conaghan, C. Richardson, B. Griffiths, M.J. Green, D. McGonagle, R.J. Wakefield, R.J. Reece, S. Miles, A. Adebajo, A. Gough, P. Helliwell, M. Martin, G. Huston, C. Pease, D.J. Veale, J. Isaacs, D.M. van der Heijde, and P. Emery Treatment of poor-prognosis early rheumatoid arthritis. A randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone Arthritis and Rheumatism 43 2000 1809 1819
-
(2000)
Arthritis and Rheumatism
, vol.43
, pp. 1809-1819
-
-
Proudman, S.M.1
Conaghan, P.G.2
Richardson, C.3
Griffiths, B.4
Green, M.J.5
McGonagle, D.6
Wakefield, R.J.7
Reece, R.J.8
Miles, S.9
Adebajo, A.10
Gough, A.11
Helliwell, P.12
Martin, M.13
Huston, G.14
Pease, C.15
Veale, D.J.16
Isaacs, J.17
Van Der Heijde, D.M.18
Emery, P.19
-
29
-
-
33644611292
-
Evaluating response to antineoplastic drug combinations in tissue culture models
-
C.P. Reynolds, and B.J. Maurer Evaluating response to antineoplastic drug combinations in tissue culture models Methods in Molecular Medicine 110 2005 173 183
-
(2005)
Methods in Molecular Medicine
, vol.110
, pp. 173-183
-
-
Reynolds, C.P.1
Maurer, B.J.2
-
30
-
-
34548606231
-
Induction of apoptosis by alkaloids, non-protein amino acids, and cardiac glycosides in human promyelotic HL-60 cells
-
V. Rosenkranz, and M. Wink Induction of apoptosis by alkaloids, non-protein amino acids, and cardiac glycosides in human promyelotic HL-60 cells Zeitschrift fur Naturforschung C 62 2007 458 466
-
(2007)
Zeitschrift fur Naturforschung C
, vol.62
, pp. 458-466
-
-
Rosenkranz, V.1
Wink, M.2
-
31
-
-
79151482960
-
Synergy research: Approaching a new generation of phytopharmaceuticals
-
H. Wagner Synergy research: approaching a new generation of phytopharmaceuticals Fitoterapia 82 2011 34 37
-
(2011)
Fitoterapia
, vol.82
, pp. 34-37
-
-
Wagner, H.1
-
32
-
-
45349085085
-
Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides
-
W. Wang, E.R. Rayburn, M. Hao, Y. Zhao, D.L. Hill, R. Zhang, and H. Wang Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides Prostate 68 2008 809 819
-
(2008)
Prostate
, vol.68
, pp. 809-819
-
-
Wang, W.1
Rayburn, E.R.2
Hao, M.3
Zhao, Y.4
Hill, D.L.5
Zhang, R.6
Wang, H.7
-
33
-
-
36049040984
-
Molecular modes of action of cytotoxic alkaloids: From DNA intercalation, spindle poisoning, topoisomerase inhibition to apoptosis and multiple drug resistance
-
M. Wink Molecular modes of action of cytotoxic alkaloids: from DNA intercalation, spindle poisoning, topoisomerase inhibition to apoptosis and multiple drug resistance The Alkaloids Chemistry and Biology Vol 64 2007 1 47
-
(2007)
The Alkaloids Chemistry and Biology
, vol.VOL
, Issue.64
, pp. 1-47
-
-
Wink, M.1
-
34
-
-
62749198712
-
Evolutionary advantage and molecular modes of action of multi-component mixtures used in phytomedicine
-
M. Wink Evolutionary advantage and molecular modes of action of multi-component mixtures used in phytomedicine Current Drug Metabolism 9 2008 996 1009
-
(2008)
Current Drug Metabolism
, vol.9
, pp. 996-1009
-
-
Wink, M.1
-
35
-
-
57649151841
-
Plant secondary metabolism: Diversity, function and its evolution
-
M. Wink Plant secondary metabolism: diversity, function and its evolution Natural Product Communications 3 2008 1205 1216
-
(2008)
Natural Product Communications
, vol.3
, pp. 1205-1216
-
-
Wink, M.1
-
38
-
-
84867623825
-
Secondary metabolites from plants inhibiting ABC transporters and reversing resistance of cancer cells and microbes to cytotoxic and antimicrobial agents
-
M. Wink, M.L. Ashour, and M.Z. El-Readi Secondary metabolites from plants inhibiting ABC transporters and reversing resistance of cancer cells and microbes to cytotoxic and antimicrobial agents Frontiers in Microbiology 3 2012 1 3
-
(2012)
Frontiers in Microbiology
, vol.3
, pp. 1-3
-
-
Wink, M.1
Ashour, M.L.2
El-Readi, M.Z.3
-
39
-
-
80051747555
-
Effect of oral administration of ginseng stem-and-leaf saponins (GSLS) on the immune responses to Newcastle disease vaccine in chickens
-
L. Zhai, Y. Li, W. Wang, Y. Wang, and S. Hu Effect of oral administration of ginseng stem-and-leaf saponins (GSLS) on the immune responses to Newcastle disease vaccine in chickens Vaccine 29 2011 5007 5014
-
(2011)
Vaccine
, vol.29
, pp. 5007-5014
-
-
Zhai, L.1
Li, Y.2
Wang, W.3
Wang, Y.4
Hu, S.5
-
40
-
-
9744254768
-
Evaluation of combination chemotherapy: Integration of nonlinear regression, curve shift, isobologram, and combination index analyses
-
L. Zhao, M.G. Wientjes, and J.L. Au Evaluation of combination chemotherapy: integration of nonlinear regression, curve shift, isobologram, and combination index analyses Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 10 2004 7994 8004
-
(2004)
Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
, vol.10
, pp. 7994-8004
-
-
Zhao, L.1
Wientjes, M.G.2
Au, J.L.3
|