Anti-connective tissue growth factor antibody treatment reduces Extracellular matrix production in Trabecular meshwork and Lamina Cribrosa cells

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 13, 2013, Pages 7836-7848

  Wallace, Deborah M ^a,b   Clark, Abbot F ^c   Lipson, Kenneth E ^d   Andrews, Darrell ^a   Crean, John K ^a   O'Brien, Colm J ^a,b  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^c UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^d FIBROGEN INC   (United States)

Author keywords

Extracellular matrix; Glaucoma pharmacology; Lamina cribrosa; Trabecular meshwork

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; FG 3019; FIBRILLIN 1; FIBRONECTIN; HYDROGEN PEROXIDE;

AGED; AQUEOUS HUMOR; ARTICLE; CATARACT; CELL ADHESION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; GLAUCOMA; HUMAN; HUMAN CELL; IMMUNOTHERAPY; LAMINA CRIBROSA CELL; MALE; OPEN ANGLE GLAUCOMA; PIGMENT EPITHELIUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SAMPLING; SCLERA; TRABECULAR MESHWORK; WESTERN BLOTTING;

EXTRACELLULAR MATRIX; GLAUCOMA PHARMACOLOGY; LAMINA CRIBROSA; TRABECULAR MESHWORK;

AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; EXTRACELLULAR MATRIX; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; MALE; TRABECULAR MESHWORK;

EID: 84888873912     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12494     Document Type: Article

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