메뉴 건너뛰기




Volumn 48, Issue 3, 2012, Pages 156-164

TGF-β2- and H2O2-induced biological changes in optic nerve head astrocytes are reduced by the antioxidant alpha-lipoic acid

Author keywords

Antioxidant; Heat shock protein; Optic nerve head

Indexed keywords

ALPHA CRYSTALLIN; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; HEAT SHOCK PROTEIN 27; HYDROGEN PEROXIDE; PARINARIC ACID; THIOCTIC ACID; TRANSFORMING GROWTH FACTOR BETA2;

EID: 84862246539     PISSN: 00303747     EISSN: 14230259     Source Type: Journal    
DOI: 10.1159/000337835     Document Type: Article
Times cited : (9)

References (58)
  • 1
    • 0033997806 scopus 로고    scopus 로고
    • The optic nerve head in glaucoma: Role of astrocytes in tissue remodeling
    • DOI 10.1016/S1350-9462(99)00017-8, PII S1350946299000178
    • Hernandez MR: The optic nerve head in glaucoma: role of astrocytes in tissue remodeling. Prog Retin Eye Res 2000; 19: 297-321. (Pubitemid 30122725)
    • (2000) Progress in Retinal and Eye Research , vol.19 , Issue.3 , pp. 297-321
    • Hernandez, M.R.1
  • 2
    • 0345016024 scopus 로고    scopus 로고
    • Glaucomatous Optic Neuropathy: When Glia Misbehave
    • DOI 10.1177/1073858403253460
    • Neufeld AH, Liu B: Glaucomatous optic neuropathy: when glia misbehave. Neuroscientist 2003; 9: 485-495. (Pubitemid 37467361)
    • (2003) Neuroscientist , vol.9 , Issue.6 , pp. 485-495
    • Neufeld, A.H.1    Liu, B.2
  • 3
    • 0033953520 scopus 로고    scopus 로고
    • Vascular and glial changes in the retrolaminar optic nerve in glaucomatous monkey eyes
    • DOI 10.1159/000027470
    • Furuyoshi N, Furuyoshi M, May CA, Hayreh SS, Alm A, Lütjen-Drecoll E: Vascular and glial changes in the retrolaminar optic nerve in glaucomatous monkey eyes. Ophthalmologica 2000; 214: 24-32. (Pubitemid 30084878)
    • (2000) Ophthalmologica , vol.214 , Issue.1 , pp. 24-32
    • Furuyoshi, N.1    Furuyoshi, M.2    May, Ch.A.3    Hayreh, S.S.4    Alm, A.5    Lutjen-Drecoll, E.6
  • 4
    • 0034071397 scopus 로고    scopus 로고
    • Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes
    • Tezel G, Hernandez R, Wax MB: Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes. Arch Ophthalmol 2000; 118: 511-518. (Pubitemid 30203146)
    • (2000) Archives of Ophthalmology , vol.118 , Issue.4 , pp. 511-518
    • Tezel, G.1    Hernandez, M.R.2    Wax, M.B.3
  • 5
    • 0028136393 scopus 로고
    • Collagen type IV gene expression in human optic nerve heads with primary open angle glaucoma
    • DOI 10.1006/exer.1994.1079
    • Hernandez MR, Ye H, Roy S: Collagen type IV gene expression in human optic nerve heads with primary open angle glaucoma. Exp Eye Res 1994; 59: 41-51. (Pubitemid 24257143)
    • (1994) Experimental Eye Research , vol.59 , Issue.1 , pp. 41-51
    • Hernandez, M.R.1    Ye, H.2    Roy, S.3
  • 6
    • 0026710995 scopus 로고
    • Extracellular matrix changes of the optic nerve lamina cribrosa in monkey eyes with experimental chronic glaucoma
    • Fukuchi T, Sawaguchi S, Hara H, Shirakashi M, Iwata K: Extracellular matrix changes of the optic nerve lamina cribrosa in monkey eyes with experimental chronic glaucoma. Graefes Arch Clin Exp Ophthalmol 1992; 230: 421-427.
    • (1992) Graefes Arch Clin Exp Ophthalmol , vol.230 , pp. 421-427
    • Fukuchi, T.1    Sawaguchi, S.2    Hara, H.3    Shirakashi, M.4    Iwata, K.5
  • 7
    • 0025021550 scopus 로고
    • Changes in the extracellular matrix of the human optic nerve head in primary open-angle glaucoma
    • Hernandez MR, Andrzejewska WM, Neufeld AH: Changes in the extracellular matrix of the human optic nerve head in primary open-angle glaucoma. Am J Ophthalmol 1990; 109: 180-188. (Pubitemid 20048416)
    • (1990) American Journal of Ophthalmology , vol.109 , Issue.2 , pp. 180-188
    • Rosario Hernandez, M.1    Andrzejewska, W.M.2    Neufeld, A.H.3
  • 8
    • 0032440847 scopus 로고    scopus 로고
    • Heat shock proteins: Regulators of stress response and apoptosis
    • DOI 10.1379/1466-1268(1998)003<0228:HSPROS>2.3.CO;2
    • Samali A, Orrenius S: Heat shock proteins: regulators of stress response and apoptosis. Cell Stress Chaperones 1998; 3: 228-236. (Pubitemid 29051822)
    • (1998) Cell Stress and Chaperones , vol.3 , Issue.4 , pp. 228-236
    • Samali, A.1    Orrenius, S.2
  • 10
    • 34648817047 scopus 로고    scopus 로고
    • Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes
    • DOI 10.1167/iovs.06-1138
    • He S, Prasanna G, Yorio T: Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes. Invest Ophthalmol Vis Sci 2007; 48: 3737-3745. (Pubitemid 351261112)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.8 , pp. 3737-3745
    • He, S.1    Prasanna, G.2    Yorio, T.3
  • 12
    • 13944249469 scopus 로고    scopus 로고
    • Transforming growth factor-β2 modulated extracellular matrix component expression in cultured human optic nerve head astrocytes
    • DOI 10.1167/iovs.04-0649
    • Fuchshofer R, Birke M, Welge-Lussen U, Kook D, Lütjen-Drecoll E: Transforming growth factor-beta 2 modulated extracellular matrix component expression in cultured human optic nerve head astrocytes. Invest Ophthalmol Vis Sci 2005; 46: 568-578. (Pubitemid 40270337)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.2 , pp. 568-578
    • Fuchshofer, R.1    Birke, M.2    Welge-Lussen, U.3    Kook, D.4    Lutjen-Drecoll, E.5
  • 13
    • 45549095234 scopus 로고    scopus 로고
    • The effect of TGFbeta2 on elastin, type VI collagen, and components of the proteolytic degradation system in human optic nerve astrocytes
    • Neumann C, Yu A, Welge-Luessen U, Lütjen-Drecoll E, Birke M: The effect of TGFbeta2 on elastin, type VI collagen, and components of the proteolytic degradation system in human optic nerve astrocytes. Invest Ophthalmol Vis Sci 2008; 49: 1464-1472.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1464-1472
    • Neumann, C.1    Yu, A.2    Welge-Luessen, U.3    Lütjen-Drecoll, E.4    Birke, M.5
  • 15
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: Cellular and molecular cues to biological function
    • Ridet JL, Malhotra SK, Privat A, Gage FH: Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 1997; 20: 570 -577.
    • (1997) Trends Neurosci , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 16
    • 20544468453 scopus 로고    scopus 로고
    • 2 for the pathogenesis of the disease
    • DOI 10.1016/j.exer.2005.02.008, PII S0014483505000606
    • Lutjen-Drecoll E: Morphological changes in glaucomatous eyes and the role of TGF-2 for the pathogenesis of the disease. Exp Eye Res 2005; 81: 1-4. (Pubitemid 40840540)
    • (2005) Experimental Eye Research , vol.81 , Issue.1 , pp. 1-4
    • Lutjen-Drecoll, E.1
  • 17
    • 0035021939 scopus 로고    scopus 로고
    • Transforming growth factor β2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development
    • Picht G, Welge-Luessen U, Grehn F, Lütjen-Drecoll E: Transforming growth factor-2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development. Graefes Arch Clin Exp Ophthalmol 2001; 239: 199-207. (Pubitemid 32422026)
    • (2001) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.239 , Issue.3 , pp. 199-207
    • Picht, C.1    Welge-Luessen, U.2    Grehn, F.3    Lutjen-Drecoll, E.4
  • 18
    • 0028592628 scopus 로고
    • Aqueous humor in glaucomatous eyes contains an increased level of TGF-2
    • Tripathi RC, Li J, Chan WFA, Tripathi BJ: Aqueous humor in glaucomatous eyes contains an increased level of TGF-2. Exp Eye Res 1994; 58: 723-727.
    • (1994) Exp Eye Res , vol.58 , pp. 723-727
    • Tripathi, R.C.1    Li, J.2    Chan, W.F.A.3    Tripathi, B.J.4
  • 19
    • 33847709462 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 is an antagonist of transforming growth factor-β2 in human trabecular meshwork cells
    • DOI 10.1167/iovs.06-0226
    • Fuchshofer R, Yu AH, Welge-Lussen U, Tamm ER: Bone morphogenetic protein-7 is an antagonist of transforming growth factor-2 in human trabecular meshwork cells. Invest Ophthalmol Vis Sci 2007; 48: 715-726. (Pubitemid 351260705)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.2 , pp. 715-726
    • Fuchshofer, R.1    Yu, A.H.L.2    Welge-Lussen, U.3    Tamm, E.R.4
  • 20
    • 34247266702 scopus 로고    scopus 로고
    • Oxidative stress in glaucoma: A burden of evidence
    • DOI 10.1097/01.ijg.0000243480.67532.1b, PII 0006119820070500000012
    • Kumar DM, Agarwal N: Oxidative stress in glaucoma: a burden of evidence. J Glaucoma 2007; 16: 334-343. (Pubitemid 46626062)
    • (2007) Journal of Glaucoma , vol.16 , Issue.3 , pp. 334-343
    • Maneesh Kumar, D.1    Agarwal, N.2
  • 21
    • 33846818874 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes
    • DOI 10.1016/j.exer.2006.10.020, PII S0014483506004234
    • Malone PE, Hernandez MR: 4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes. Exp Eye Res 2007; 84: 444-454. (Pubitemid 46210058)
    • (2007) Experimental Eye Research , vol.84 , Issue.3 , pp. 444-454
    • Malone, P.E.1    Hernandez, M.R.2
  • 22
    • 33846810059 scopus 로고    scopus 로고
    • Glaucomatous outflow pathway and oxidative stress
    • DOI 10.1016/j.exer.2006.10.008, PII S0014483506004155
    • Sacca SC, Izzotti A, Rossi P, Traverso C: Glaucomatous outflow pathway and oxidative stress. Exp Eye Res 2007; 84: 389-399. (Pubitemid 46210055)
    • (2007) Experimental Eye Research , vol.84 , Issue.3 , pp. 389-399
    • Sacca, S.C.1    Izzotti, A.2    Rossi, P.3    Traverso, C.4
  • 23
    • 33847651241 scopus 로고    scopus 로고
    • TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells
    • Proell V, Carmona-Cuenca I, Murillo MM, Huber H, Fabregat I, Mikulits W: TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells. Comp Hepatol 2007; 6: 1.
    • (2007) Comp Hepatol , vol.6 , pp. 1
    • Proell, V.1    Carmona-Cuenca, I.2    Murillo, M.M.3    Huber, H.4    Fabregat, I.5    Mikulits, W.6
  • 25
    • 33751019429 scopus 로고    scopus 로고
    • 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: Roles of NADPH oxidase, mitochondria, and lipid rafts
    • DOI 10.1016/j.freeradbiomed.2006.09.006, PII S0891584906005673
    • Valencia A, Rajadurai A, Carle AB, Kochevar IE: 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts. Free Radic Biol Med 2006; 41: 1704-1718. (Pubitemid 44740271)
    • (2006) Free Radical Biology and Medicine , vol.41 , Issue.11 , pp. 1704-1718
    • Valencia, A.1    Rajadurai, A.2    Carle, A.B.3    Kochevar, I.E.4
  • 27
    • 33748677104 scopus 로고    scopus 로고
    • Oxidative stress in glaucomatous neurodegeneration: Mechanisms and consequences
    • DOI 10.1016/j.preteyeres.2006.07.003, PII S1350946206000280
    • Tezel G: Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. Prog Retin Eye Res 2006; 25: 490-513. (Pubitemid 44389961)
    • (2006) Progress in Retinal and Eye Research , vol.25 , Issue.5 , pp. 490-513
    • Tezel, G.1
  • 28
    • 0032733691 scopus 로고    scopus 로고
    • The role of oxidative stress in Alzheimer disease
    • Markesbery WR: The role of oxidative stress in Alzheimer disease. Arch Neurol 1999; 56: 1449-1452.
    • (1999) Arch Neurol , vol.56 , pp. 1449-1452
    • Markesbery, W.R.1
  • 29
    • 33947310739 scopus 로고    scopus 로고
    • Diabetic painful neuropathy: Current and future treatment options
    • DOI 10.2165/00003495-200767040-00006
    • Chong MS, Hester J: Diabetic painful neuropathy: current and future treatment options. Drugs 2007; 67: 569-585. (Pubitemid 46440313)
    • (2007) Drugs , vol.67 , Issue.4 , pp. 569-585
    • Chong, M.S.1    Hester, J.2
  • 30
    • 38049136702 scopus 로고    scopus 로고
    • Diabetic neuropathy: New strategies for treatment
    • Várkonyi T, Kempler P: Diabetic neuropathy: new strategies for treatment. Diabetes Obes Metab 2008; 10: 99-108.
    • (2008) Diabetes Obes Metab , vol.10 , pp. 99-108
    • Várkonyi, T.1    Kempler, P.2
  • 31
    • 47249106357 scopus 로고    scopus 로고
    • Lipoic acid: A novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS
    • Salinthone S, Yadav V, Bourdette DN, Carr DW: Lipoic acid: a novel therapeutic approach for multiple sclerosis and other chronic inflammatory diseases of the CNS. Endocr Metab Immune Disord Drug Targets 2008; 8: 132-142.
    • (2008) Endocr Metab Immune Disord Drug Targets , vol.8 , pp. 132-142
    • Salinthone, S.1    Yadav, V.2    Bourdette, D.N.3    Carr, D.W.4
  • 32
    • 2342544918 scopus 로고    scopus 로고
    • Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress
    • Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM: Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr Med Chem 2004; 11: 1135-1146. (Pubitemid 38585058)
    • (2004) Current Medicinal Chemistry , vol.11 , Issue.9 , pp. 1135-1146
    • Smith, A.R.1    Shenvi, S.V.2    Widlansky, M.3    Suh, J.H.4    Hagen, T.M.5
  • 33
    • 33644664987 scopus 로고    scopus 로고
    • Lipoic acid - The drug of the future
    • Bilska A, Wlodek L: Lipoic acid - the drug of the future? Pharmacol Rep 2005; 57: 570-577
    • (2005) Pharmacol Rep , vol.57 , pp. 570-577
    • Bilska, A.1    Wlodek, L.2
  • 34
    • 34250711866 scopus 로고    scopus 로고
    • A novel perspective on natural therapeutic approaches in glaucoma therapy
    • DOI 10.1517/14728214.12.2.195
    • Mozaffarieh M, Flammer J: A novel perspective on natural therapeutic approaches in glaucoma therapy. Expert Opin Emerg Drugs 2007; 12: 195-198. (Pubitemid 46953561)
    • (2007) Expert Opinion on Emerging Drugs , vol.12 , Issue.2 , pp. 195-198
    • Mozaffarieh, M.1    Flammer, J.2
  • 35
    • 46649083004 scopus 로고    scopus 로고
    • Oxidative and nitrative stress markers in glaucoma
    • Aslan M, Cort A, Yucel I: Oxidative and nitrative stress markers in glaucoma. Free Radic Biol Med 2008; 45: 367-376.
    • (2008) Free Radic Biol Med , vol.45 , pp. 367-376
    • Aslan, M.1    Cort, A.2    Yucel, I.3
  • 36
    • 0242569638 scopus 로고    scopus 로고
    • Purification of astrocytes from adult human optic nerve heads by immunopanning
    • DOI 10.1016/S1385-299X(03)00073-4
    • Yang P, Hernandez MR: Purification of astrocytes from adult human optic nerve heads by immunopanning. Brain Res Brain Protoc 2003; 12: 67-76. (Pubitemid 37410234)
    • (2003) Brain Research Protocols , vol.12 , Issue.2 , pp. 67-76
    • Yang, P.1    Hernandez, M.R.2
  • 37
    • 0031194332 scopus 로고    scopus 로고
    • Expression of neural cell adhesion molecule (NCAM) characterizes a subpopulation of type 1 astrocytes in human optic nerve head
    • DOI 10.1002/(SICI)1098-1136(199707)20:3<262::AID-GLIA10>3.0.CO;2-S
    • Kobayashi S, Vidal I, Pena JD, Hernandez MR: Expression of neural cell adhesion molecule (NCAM) characterizes a subpopulation of type 1 astrocytes in human optic nerve head. Glia 1997; 20: 262-273. (Pubitemid 27324312)
    • (1997) GLIA , vol.20 , Issue.3 , pp. 262-273
    • Kobayashi, S.1    Vidal, I.2    Pena, J.D.O.3    Hernandez, M.R.4
  • 40
    • 0030700795 scopus 로고    scopus 로고
    • Further similarities between astrocytes and perisinusoidal stellate cells of liver (Ito cells): Colocalization of desmin and glial fibrillary acidic protein in astroglial primary cultures
    • DOI 10.1016/S0248-4900(97)80034-2
    • Buniatian GH: Further similarities between astrocytes and perisinusoidal stellate cells of liver (Ito cells): colocalization of desmin and glial fibrillary acidic protein in astroglial primary cultures. Biol Cell 1997; 89: 169-177. (Pubitemid 27519163)
    • (1997) Biology of the Cell , vol.89 , Issue.3 , pp. 169-177
    • Buniatian, G.H.1
  • 41
    • 33646071538 scopus 로고    scopus 로고
    • The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation
    • Esposito G, De Filippis D, Cirillo C, Sarnelli G, Cuomo R, Iuvone T: The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation. Life Sci 2006; 78: 2707-2715.
    • (2006) Life Sci , vol.78 , pp. 2707-2715
    • Esposito, G.1    De Filippis, D.2    Cirillo, C.3    Sarnelli, G.4    Cuomo, R.5    Iuvone, T.6
  • 42
    • 0028928357 scopus 로고
    • The S100 protein family: History, function, and expression
    • Zimmer DB, Cornwall EH, Landar A, Song W: The S100 protein family: history, function, and expression. Brain Res Bull 1995; 37: 417-429.
    • (1995) Brain Res Bull , vol.37 , pp. 417-429
    • Zimmer, D.B.1    Cornwall, E.H.2    Landar, A.3    Song, W.4
  • 43
    • 34548382456 scopus 로고    scopus 로고
    • Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
    • DOI 10.1093/mutage/gem001
    • Hodges NJ, Green RM, Chipman JK, Graham M: Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression. Mutagenesis 2007; 22: 189-194. (Pubitemid 47355707)
    • (2007) Mutagenesis , vol.22 , Issue.3 , pp. 189-194
    • Hodges, N.J.1    Green, R.M.2    Chipman, J.K.3    Graham, M.4
  • 44
    • 0034535879 scopus 로고    scopus 로고
    • Fluorescent probes as markers of oxidative stress in keratinocyte cell lines following UVB exposure
    • DOI 10.1016/S0014-827X(00)00037-9, PII S0014827X00000379
    • Carini M, Aldini G, Piccone M, Faccino RM: Fluorescent probes as markers of oxidative stress in keratinocyte cell lines following UVB exposure. Farmaco 2000; 55: 526-534. (Pubitemid 32007895)
    • (2000) Farmaco , vol.55 , Issue.8 , pp. 526-534
    • Carini, M.1    Aldini, G.2    Piccone, M.3    Facino, R.M.4
  • 46
    • 58149237345 scopus 로고    scopus 로고
    • Oxidative stress and TGF-beta2 increase heat shock protein 27 expression in human optic nerve head astrocytes
    • Yu AL, Fuchshofer R, Birke M, Kampik A, Bloemendal H, Welge-Lüssen U: Oxidative stress and TGF-beta2 increase heat shock protein 27 expression in human optic nerve head astrocytes. Invest Ophthalmol Vis Sci 2008; 49: 5403-5411.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 5403-5411
    • Yu, A.L.1    Fuchshofer, R.2    Birke, M.3    Kampik, A.4    Bloemendal, H.5    Welge-Lüssen, U.6
  • 47
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • DOI 10.1016/0165-6147(90)90184-A
    • Meldrum B, Garthwaite J: Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 1990; 11: 379-387. (Pubitemid 20262465)
    • (1990) Trends in Pharmacological Sciences , vol.11 , Issue.9 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 49
    • 36549058155 scopus 로고    scopus 로고
    • Antagonizing TGF-beta induced liver fibrosis by a retinoic acid derivative through regulation of ROS and calcium influx
    • Yang KL, Chang WT, Chuang CC, Hung KC, Li El: Antagonizing TGF-beta induced liver fibrosis by a retinoic acid derivative through regulation of ROS and calcium influx. Biochem Biophys Res Commun 2008; 365: 484-489.
    • (2008) Biochem Biophys Res Commun , vol.365 , pp. 484-489
    • Yang, K.L.1    Chang, W.T.2    Chuang, C.C.3    Hung, K.C.4    El, L.5
  • 50
    • 3142521808 scopus 로고    scopus 로고
    • Functional dichotomy: Glutathione and vitamin E in homeostasis relevant to primary open-angle glaucoma
    • DOI 10.1079/BJN20041113
    • Veach J: Functional dichotomy: glutathione and vitamin E in homeostasis relevant to primary open-angle glaucoma. Br J Nutr 2004; 91: 809-829. (Pubitemid 38931445)
    • (2004) British Journal of Nutrition , vol.91 , Issue.6 , pp. 809-829
    • Veach, J.1
  • 51
    • 41149154270 scopus 로고    scopus 로고
    • LEDGF binding to stress response element increases alphaB-crystallin expression in astrocytes with oxidative stress
    • Shin JH, Piao CS, Lim CM, Lee JK: LEDGF binding to stress response element increases alphaB-crystallin expression in astrocytes with oxidative stress. Neurosci Lett 2008; 435: 131-136.
    • (2008) Neurosci Lett , vol.435 , pp. 131-136
    • Shin, J.H.1    Piao, C.S.2    Lim, C.M.3    Lee, J.K.4
  • 52
    • 2942733447 scopus 로고    scopus 로고
    • Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead
    • DOI 10.1016/j.taap.2004.03.001, PII S0041008X04001474
    • Cabell L, Ferguson C, Luginbill D, Kern M, Weingart A, Audesirk G: Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead. Toxicol Appl Pharmacol 2004; 198: 49-60. (Pubitemid 38789128)
    • (2004) Toxicology and Applied Pharmacology , vol.198 , Issue.1 , pp. 49-60
    • Cabell, L.1    Ferguson, C.2    Luginbill, D.3    Kern, M.4    Weingart, A.5    Audesirk, G.6
  • 53
    • 33847184944 scopus 로고    scopus 로고
    • Alpha-lipoic acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney expression in streptozotocin-induced diabetic rat kidney
    • Oksala NK, Lappalainen J, Laaksonen DE, Khanna S, Kaarniranta K, Sen CK, Atalay M: Alpha-lipoic acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney expression in streptozotocin-induced diabetic rat kidney. Antioxid Redox Signal 2007; 9: 497-506.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 497-506
    • Oksala, N.K.1    Lappalainen, J.2    Laaksonen, D.E.3    Khanna, S.4    Kaarniranta, K.5    Sen, C.K.6    Atalay, M.7
  • 54
    • 34447536731 scopus 로고    scopus 로고
    • 2 induces protective events via the p38-MAPK signalling pathway and ANP in the perfused amphibian heart
    • DOI 10.1242/jeb.003178
    • Gaitanaki C, Kalpachidou T, Aggeli IK, Papazafiri P, Beis I: CoCl 2 induces protective events via the p38-MAPK signalling pathway and ANP in the perfused amphibian heart. J Exp Biol 2007; 210: 2267-2277. (Pubitemid 47080205)
    • (2007) Journal of Experimental Biology , vol.210 , Issue.13 , pp. 2267-2277
    • Gaitanaki, C.1    Kalpachidou, T.2    Aggeli, I.-K.S.3    Papazafiri, P.4    Beis, I.5
  • 55
    • 33845933757 scopus 로고    scopus 로고
    • Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and α-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease
    • DOI 10.1016/j.freeradbiomed.2006.11.006, PII S0891584906007076
    • Abdul HM, Butterfield DA: Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl- L -carnitine and alphalipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Free Radic Biol Med 2007; 42: 371-384. (Pubitemid 46038045)
    • (2007) Free Radical Biology and Medicine , vol.42 , Issue.3 , pp. 371-384
    • Mohmmad Abdul, H.1    Butterfield, D.A.2
  • 58
    • 33646344983 scopus 로고    scopus 로고
    • Lipoic acid supplementation prevents cyclosporine-induced hypertension and nephrotoxicity in spontaneously hypertensive rats
    • DOI 10.1097/01.hjh.0000222766.37971.9f, PII 0000487220060500000024
    • Louhelainen M, Merasto S, Finckenberg P, Lapatto R, Cheng ZJ, Mervaala EM: Lipoic acid supplementation prevents cyclosporine-induced hypertension and nephrotoxicity in spontaneously hypertensive rats. J Hypertens 2006; 24: 947-956. (Pubitemid 43670467)
    • (2006) Journal of Hypertension , vol.24 , Issue.5 , pp. 947-956
    • Louhelainen, M.1    Merasto, S.2    Finckenberg, P.3    Lapatto, R.4    Zhong, J.C.5    Mervaala, E.M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.