Pesticide exposure and genetic variation in xenobiotic-metabolizing enzymes interact to induce biochemical liver damage

Food and Chemical Toxicology

Volumn 61, Issue , 2013, Pages 144-151

  Hernández, Antonio F ^a   Gil, Fernando ^a   Lacasaña, Marina ^b,c   Rodríguez Barranco, Miguel ^b   Tsatsakis, Aristidis M ^d   Requena, Mar ^e   Parrón, Tesifón ^e,f   Alarcón, Raquel ^f  

^a UNIVERSITY OF GRANADA   (Spain)

^b ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^c CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^d UNIVERSITY OF CRETE   (Greece)

^e Council of Health at Almeria Province ^*  (Spain)

^f UNIVERSITY OF ALMERÍA   (Spain)

Author keywords

Gene environment interactions; Genetic polymorphisms; Liver function test; Occupational health; Pesticide exposure

Indexed keywords

ACETYLCHOLINESTERASE; ALKALINE PHOSPHATASE; ARYLDIALKYLPHOSPHATASE 1; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PESTICIDE; TRIACYLGLYCEROL; XENOBIOTIC AGENT;

ADOLESCENT; ADULT; AGRICULTURAL WORKER; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL CHEMISTRY; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; FUNCTIONAL ASSESSMENT; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HUMAN; LIPID BLOOD LEVEL; LIVER TOXICITY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE;

GENE-ENVIRONMENT INTERACTIONS; GENETIC POLYMORPHISMS; LIVER FUNCTION TEST; OCCUPATIONAL HEALTH; PESTICIDE EXPOSURE;

ACETYLCHOLINESTERASE; ADOLESCENT; ADULT; AGRICULTURE; ARYLDIALKYLPHOSPHATASE; CASE-CONTROL STUDIES; CHOLESTEROL; CHOLESTEROL, LDL; ENZYMES; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC VARIATION; GLUTATHIONE TRANSFERASE; HAPLOTYPES; HUMANS; LIVER; LONGITUDINAL STUDIES; MALE; METABOLIC DETOXICATION, DRUG; MIDDLE AGED; OCCUPATIONAL EXPOSURE; PESTICIDES; POLYMORPHISM, GENETIC; SPAIN; YOUNG ADULT;

EID: 84888844483     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.05.012     Document Type: Article

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