No direct hepatotoxic potential following a multiple-low dose paraquat exposure in rat as related to its bioaccumulation

Toxicology Letters

Volumn 170, Issue 3, 2007, Pages 193-202

  Podprasart, Varaporn ^a   Satayavivad, Jutamaad ^a   Riengrojpitak, Suda ^a   Wilairat, Prapin ^a   Wananukul, Winai ^b   Chavalittumrong, Pranee ^c   Chivapat, Songpol ^c   Yoovathaworn, Krongtong ^a  

^a Mahidol University   (Thailand)

^b THAMMASAT UNIVERSITY   (Thailand)

^c MINISTRY OF PUBLIC HEALTH   (Thailand)

Author keywords

Accumulation; CYP; Enzymes; Hepatotoxicity; Paraquat

Indexed keywords

ALBUMIN; AMINOTRANSFERASE; BILIRUBIN; CYTOCHROME P450 1A1; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; ETHOXYRESORUFIN DEETHYLASE; PARAQUAT;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; BIOACCUMULATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOALBUMINEMIA; LIVER FUNCTION; LIVER MICROSOME METABOLISM; LIVER TOXICITY; LUNG TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICOKINETICS; XENOBIOTIC METABOLISM;

ANIMALS; CELL SHAPE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HEPATITIS, TOXIC; HERBICIDES; LIVER; LIVER FUNCTION TESTS; LUNG; MALE; PARAQUAT; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

RATTUS; RATTUS NORVEGICUS;

EID: 34248152562     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2007.03.006     Document Type: Article

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