-
1
-
-
67749116467
-
Identification of the C1q-binding sites of human C1r and C1s: a refined three-dimensional model of the C1 complex of complement
-
Bally I., Rossi V., Lunardi T., Thielens N.M., Gaboriaud C., Arlaud G.J. Identification of the C1q-binding sites of human C1r and C1s: a refined three-dimensional model of the C1 complex of complement. J Biol Chem 2009, 284:19340-19348.
-
(2009)
J Biol Chem
, vol.284
, pp. 19340-19348
-
-
Bally, I.1
Rossi, V.2
Lunardi, T.3
Thielens, N.M.4
Gaboriaud, C.5
Arlaud, G.J.6
-
2
-
-
67649232598
-
Analogous interactions in initiating complexes of the classical and lectin pathways of complement
-
Phillips A.E., Toth J., Dodds A.W., Girija U.V., Furze C.M., Pala E., Sim R.B., Reid K.B., Schwaeble W.J., Schmid R., et al. Analogous interactions in initiating complexes of the classical and lectin pathways of complement. J Immunol 2009, 182:7708-7717.
-
(2009)
J Immunol
, vol.182
, pp. 7708-7717
-
-
Phillips, A.E.1
Toth, J.2
Dodds, A.W.3
Girija, U.V.4
Furze, C.M.5
Pala, E.6
Sim, R.B.7
Reid, K.B.8
Schwaeble, W.J.9
Schmid, R.10
-
3
-
-
0036469280
-
The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex
-
Budayova-Spano M., Lacroix M., Thielens N.M., Arlaud G.J., Fontecilla-Camps J.C., Gaboriaud C. The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex. EMBO J 2002, 21:231-239.
-
(2002)
EMBO J
, vol.21
, pp. 231-239
-
-
Budayova-Spano, M.1
Lacroix, M.2
Thielens, N.M.3
Arlaud, G.J.4
Fontecilla-Camps, J.C.5
Gaboriaud, C.6
-
4
-
-
0030053692
-
The reaction mechanism of the internal thioester in the human complement component C4
-
Dodds A.W., Ren X.D., Willis A.C., Law S.K. The reaction mechanism of the internal thioester in the human complement component C4. Nature 1996, 379:177-179.
-
(1996)
Nature
, vol.379
, pp. 177-179
-
-
Dodds, A.W.1
Ren, X.D.2
Willis, A.C.3
Law, S.K.4
-
5
-
-
78650637010
-
Collectin 11 (CL-11 CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity
-
Hansen S., Selman L., Palaniyar N., Ziegler K., Brandt J., Kliem A., Jonasson M., Skjoedt M.O., Nielsen O., Hartshorn K., et al. Collectin 11 (CL-11 CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity. J Immunol 2010, 185:6096-6104.
-
(2010)
J Immunol
, vol.185
, pp. 6096-6104
-
-
Hansen, S.1
Selman, L.2
Palaniyar, N.3
Ziegler, K.4
Brandt, J.5
Kliem, A.6
Jonasson, M.7
Skjoedt, M.O.8
Nielsen, O.9
Hartshorn, K.10
-
6
-
-
0030068057
-
A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin
-
Matsushita M., Endo Y., Taira S., Sato Y., Fujita T., Ichikawa N., Nakata M., Mizuochi T. A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin. J Biol Chem 1996, 271:2448-2454.
-
(1996)
J Biol Chem
, vol.271
, pp. 2448-2454
-
-
Matsushita, M.1
Endo, Y.2
Taira, S.3
Sato, Y.4
Fujita, T.5
Ichikawa, N.6
Nakata, M.7
Mizuochi, T.8
-
7
-
-
14044278783
-
The two major oligomeric forms of human mannan-binding lectin: chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated serine proteases
-
Teillet F., Dublet B., Andrieu J.P., Gaboriaud C., Arlaud G.J., Thielens N.M. The two major oligomeric forms of human mannan-binding lectin: chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated serine proteases. J Immunol 2005, 174:2870-2877.
-
(2005)
J Immunol
, vol.174
, pp. 2870-2877
-
-
Teillet, F.1
Dublet, B.2
Andrieu, J.P.3
Gaboriaud, C.4
Arlaud, G.J.5
Thielens, N.M.6
-
8
-
-
77956876323
-
Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system
-
Degn S.E., Jensen L., Gal P., Dobo J., Holmvad S.H., Jensenius J.C., Thiel S. Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system. J Immunol Methods 2010, 361:37-50.
-
(2010)
J Immunol Methods
, vol.361
, pp. 37-50
-
-
Degn, S.E.1
Jensen, L.2
Gal, P.3
Dobo, J.4
Holmvad, S.H.5
Jensenius, J.C.6
Thiel, S.7
-
9
-
-
0026445745
-
Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease
-
Matsushita M., Fujita T. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease. J Exp Med 1992, 176:1497-1502.
-
(1992)
J Exp Med
, vol.176
, pp. 1497-1502
-
-
Matsushita, M.1
Fujita, T.2
-
10
-
-
0028343828
-
Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein
-
Sato T., Endo Y., Matsushita M., Fujita T. Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein. Int Immunol 1994, 6:665-669.
-
(1994)
Int Immunol
, vol.6
, pp. 665-669
-
-
Sato, T.1
Endo, Y.2
Matsushita, M.3
Fujita, T.4
-
11
-
-
0034897825
-
MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway
-
Dahl M.R., Thiel S., Matsushita M., Fujita T., Willis A.C., Christensen T., Vorup-Jensen T., Jensenius J.C. MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity 2001, 15:127-135.
-
(2001)
Immunity
, vol.15
, pp. 127-135
-
-
Dahl, M.R.1
Thiel, S.2
Matsushita, M.3
Fujita, T.4
Willis, A.C.5
Christensen, T.6
Vorup-Jensen, T.7
Jensenius, J.C.8
-
12
-
-
73349128762
-
MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation
-
Degn S.E., Hansen A.G., Steffensen R., Jacobsen C., Jensenius J.C., Thiel S. MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation. J Immunol 2009, 183:7371-7378.
-
(2009)
J Immunol
, vol.183
, pp. 7371-7378
-
-
Degn, S.E.1
Hansen, A.G.2
Steffensen, R.3
Jacobsen, C.4
Jensenius, J.C.5
Thiel, S.6
-
13
-
-
0030950185
-
A second serine protease associated with mannan-binding lectin that activates complement
-
Thiel S., Vorup-Jensen T., Stover C.M., Schwaeble W., Laursen S.B., Poulsen K., Willis A.C., Eggleton P., Hansen S., Holmskov U., et al. A second serine protease associated with mannan-binding lectin that activates complement. Nature 1997, 386:506-510.
-
(1997)
Nature
, vol.386
, pp. 506-510
-
-
Thiel, S.1
Vorup-Jensen, T.2
Stover, C.M.3
Schwaeble, W.4
Laursen, S.B.5
Poulsen, K.6
Willis, A.C.7
Eggleton, P.8
Hansen, S.9
Holmskov, U.10
-
14
-
-
0033559136
-
Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene
-
Stover C.M., Thiel S., Thelen M., Lynch N.J., Vorup-Jensen T., Jensenius J.C., Schwaeble W.J. Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene. J Immunol 1999, 162:3481-3490.
-
(1999)
J Immunol
, vol.162
, pp. 3481-3490
-
-
Stover, C.M.1
Thiel, S.2
Thelen, M.3
Lynch, N.J.4
Vorup-Jensen, T.5
Jensenius, J.C.6
Schwaeble, W.J.7
-
15
-
-
0032958112
-
A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway
-
Takahashi M., Endo Y., Fujita T., Matsushita M. A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway. Int Immunol 1999, 11:859-863.
-
(1999)
Int Immunol
, vol.11
, pp. 859-863
-
-
Takahashi, M.1
Endo, Y.2
Fujita, T.3
Matsushita, M.4
-
16
-
-
84875987157
-
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway
-
Megyeri M., Harmat V., Major B., Vegh A., Balczer J., Heja D., Szilagyi K., Datz D., Pal G., Zavodszky P., et al. Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway. J Biol Chem 2013, 288:8922-8934.
-
(2013)
J Biol Chem
, vol.288
, pp. 8922-8934
-
-
Megyeri, M.1
Harmat, V.2
Major, B.3
Vegh, A.4
Balczer, J.5
Heja, D.6
Szilagyi, K.7
Datz, D.8
Pal, G.9
Zavodszky, P.10
-
17
-
-
2942746426
-
Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases
-
Chen C.B., Wallis R. Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases. J Biol Chem 2004, 279:26058-26065.
-
(2004)
J Biol Chem
, vol.279
, pp. 26058-26065
-
-
Chen, C.B.1
Wallis, R.2
-
18
-
-
78650638514
-
Structures of C3b in complex with factors B and D give insight into complement convertase formation
-
Forneris F., Ricklin D., Wu J., Tzekou A., Wallace R.S., Lambris J.D., Gros P. Structures of C3b in complex with factors B and D give insight into complement convertase formation. Science 2010, 330:1816-1820.
-
(2010)
Science
, vol.330
, pp. 1816-1820
-
-
Forneris, F.1
Ricklin, D.2
Wu, J.3
Tzekou, A.4
Wallace, R.S.5
Lambris, J.D.6
Gros, P.7
-
19
-
-
67649230210
-
Structure of complement fragment C3b-factor H and implications for host protection by complement regulators
-
Wu J., Wu Y.Q., Ricklin D., Janssen B.J., Lambris J.D., Gros P. Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat Immunol 2009, 10:728-733.
-
(2009)
Nat Immunol
, vol.10
, pp. 728-733
-
-
Wu, J.1
Wu, Y.Q.2
Ricklin, D.3
Janssen, B.J.4
Lambris, J.D.5
Gros, P.6
-
20
-
-
77953266787
-
The amplification loop of the complement pathways
-
Lachmann P.J. The amplification loop of the complement pathways. Adv Immunol 2009, 104:115-149.
-
(2009)
Adv Immunol
, vol.104
, pp. 115-149
-
-
Lachmann, P.J.1
-
21
-
-
84878417006
-
Molecular determinants of the substrate specificity of the complement-initiating protease, C1r
-
Wijeyewickrema L.C., Yongqing T., Tran T.P., Thompson P.E., Viljoen J.E., Coetzer T.H., Duncan R.C., Kass I., Buckle A.M., Pike R.N. Molecular determinants of the substrate specificity of the complement-initiating protease, C1r. J Biol Chem 2013, 288:15571-15580.
-
(2013)
J Biol Chem
, vol.288
, pp. 15571-15580
-
-
Wijeyewickrema, L.C.1
Yongqing, T.2
Tran, T.P.3
Thompson, P.E.4
Viljoen, J.E.5
Coetzer, T.H.6
Duncan, R.C.7
Kass, I.8
Buckle, A.M.9
Pike, R.N.10
-
22
-
-
80053548921
-
The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway
-
Iwaki D., Kanno K., Takahashi M., Endo Y., Matsushita M., Fujita T. The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway. J Immunol 2011, 187:3751-3758.
-
(2011)
J Immunol
, vol.187
, pp. 3751-3758
-
-
Iwaki, D.1
Kanno, K.2
Takahashi, M.3
Endo, Y.4
Matsushita, M.5
Fujita, T.6
-
23
-
-
84867324414
-
Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function
-
Degn S.E., Jensen L., Hansen A.G., Duman D., Tekin M., Jensenius J.C., Thiel S. Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function. J Immunol 2012, 189:3957-3969.
-
(2012)
J Immunol
, vol.189
, pp. 3957-3969
-
-
Degn, S.E.1
Jensen, L.2
Hansen, A.G.3
Duman, D.4
Tekin, M.5
Jensenius, J.C.6
Thiel, S.7
-
24
-
-
84874884781
-
Comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function"
-
Takahashi M., Sekine H., Endo Y., Fujita T. Comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function". J Immunol 2013, 190:2477.
-
(2013)
J Immunol
, vol.190
, pp. 2477
-
-
Takahashi, M.1
Sekine, H.2
Endo, Y.3
Fujita, T.4
-
25
-
-
84874884781
-
Response to comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function"
-
Degn S.E., Jensenius J.C., Thiel S. Response to comment on "Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function". J Immunol 2013, 190:2477-2478.
-
(2013)
J Immunol
, vol.190
, pp. 2477-2478
-
-
Degn, S.E.1
Jensenius, J.C.2
Thiel, S.3
-
26
-
-
33745121562
-
Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5
-
Cortesio C.L., Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys 2006, 449:164-170.
-
(2006)
Arch Biochem Biophys
, vol.449
, pp. 164-170
-
-
Cortesio, C.L.1
Jiang, W.2
-
27
-
-
79952186905
-
Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome
-
Rooryck C., Diaz-Font A., Osborn D.P., Chabchoub E., Hernandez-Hernandez V., Shamseldin H., Kenny J., Waters A., Jenkins D., Kaissi A.A., et al. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet 2011, 43:197-203.
-
(2011)
Nat Genet
, vol.43
, pp. 197-203
-
-
Rooryck, C.1
Diaz-Font, A.2
Osborn, D.P.3
Chabchoub, E.4
Hernandez-Hernandez, V.5
Shamseldin, H.6
Kenny, J.7
Waters, A.8
Jenkins, D.9
Kaissi, A.A.10
-
28
-
-
0029130195
-
Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells
-
Mohan S., Nakao Y., Honda Y., Landale E., Leser U., Dony C., Lang K., Baylink D.J. Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells. J Biol Chem 1995, 270:20424-20431.
-
(1995)
J Biol Chem
, vol.270
, pp. 20424-20431
-
-
Mohan, S.1
Nakao, Y.2
Honda, Y.3
Landale, E.4
Leser, U.5
Dony, C.6
Lang, K.7
Baylink, D.J.8
-
29
-
-
0033305191
-
Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo
-
Richman C., Baylink D.J., Lang K., Dony C., Mohan S. Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo. Endocrinology 1999, 140:4699-4705.
-
(1999)
Endocrinology
, vol.140
, pp. 4699-4705
-
-
Richman, C.1
Baylink, D.J.2
Lang, K.3
Dony, C.4
Mohan, S.5
-
30
-
-
84881251840
-
The X-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the 3MC syndrome
-
Yongqing T., Wilmann P.G., Reeve S.B., Coetzer T.H., Smith A.I., Whisstock J.C., Pike R.N., Wijeyewickrema L.C. The X-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the 3MC syndrome. J Biol Chem 2013, 288:22399-22407.
-
(2013)
J Biol Chem
, vol.288
, pp. 22399-22407
-
-
Yongqing, T.1
Wilmann, P.G.2
Reeve, S.B.3
Coetzer, T.H.4
Smith, A.I.5
Whisstock, J.C.6
Pike, R.N.7
Wijeyewickrema, L.C.8
-
31
-
-
0031964708
-
Baculovirus-mediated expression of truncated modular fragments from the catalytic region of human complement serine protease C1s. Evidence for the involvement of both complement control protein modules in the recognition of the C4 protein substrate
-
Rossi V., Bally I., Thielens N.M., Esser A.F., Arlaud G.J. Baculovirus-mediated expression of truncated modular fragments from the catalytic region of human complement serine protease C1s. Evidence for the involvement of both complement control protein modules in the recognition of the C4 protein substrate. J Biol Chem 1998, 273:1232-1239.
-
(1998)
J Biol Chem
, vol.273
, pp. 1232-1239
-
-
Rossi, V.1
Bally, I.2
Thielens, N.M.3
Esser, A.F.4
Arlaud, G.J.5
-
32
-
-
0037310722
-
Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments
-
Ambrus G., Gal P., Kojima M., Szilagyi K., Balczer J., Antal J., Graf L., Laich A., Moffatt B.E., Schwaeble W., et al. Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments. J Immunol 2003, 170:1374-1382.
-
(2003)
J Immunol
, vol.170
, pp. 1374-1382
-
-
Ambrus, G.1
Gal, P.2
Kojima, M.3
Szilagyi, K.4
Balczer, J.5
Antal, J.6
Graf, L.7
Laich, A.8
Moffatt, B.E.9
Schwaeble, W.10
-
33
-
-
25444528435
-
Functional role of the linker between the complement control protein modules of complement protease C1s
-
Bally I., Rossi V., Thielens N.M., Gaboriaud C., Arlaud G.J. Functional role of the linker between the complement control protein modules of complement protease C1s. J Immunol 2005, 175:4536-4542.
-
(2005)
J Immunol
, vol.175
, pp. 4536-4542
-
-
Bally, I.1
Rossi, V.2
Thielens, N.M.3
Gaboriaud, C.4
Arlaud, G.J.5
-
34
-
-
29644445934
-
Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement control protein modules
-
Rossi V., Teillet F., Thielens N.M., Bally I., Arlaud G.J. Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement control protein modules. J Biol Chem 2005, 280:41811-41818.
-
(2005)
J Biol Chem
, vol.280
, pp. 41811-41818
-
-
Rossi, V.1
Teillet, F.2
Thielens, N.M.3
Bally, I.4
Arlaud, G.J.5
-
35
-
-
84655176522
-
Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4
-
Duncan R.C., Bergstrom F., Coetzer T.H., Blom A.M., Wijeyewickrema L.C., Pike R.N. Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4. Mol Immunol 2012, 49:593-600.
-
(2012)
Mol Immunol
, vol.49
, pp. 593-600
-
-
Duncan, R.C.1
Bergstrom, F.2
Coetzer, T.H.3
Blom, A.M.4
Wijeyewickrema, L.C.5
Pike, R.N.6
-
36
-
-
84865419895
-
Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s
-
Duncan R.C., Mohlin F., Taleski D., Coetzer T.H., Huntington J.A., Payne R.J., Blom A.M., Pike R.N., Wijeyewickrema L.C. Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s. J Immunol 2012, 189:2365-2373.
-
(2012)
J Immunol
, vol.189
, pp. 2365-2373
-
-
Duncan, R.C.1
Mohlin, F.2
Taleski, D.3
Coetzer, T.H.4
Huntington, J.A.5
Payne, R.J.6
Blom, A.M.7
Pike, R.N.8
Wijeyewickrema, L.C.9
-
37
-
-
84866558185
-
Structural basis for activation of the complement system by component C4 cleavage
-
Kidmose R.T., Laursen N.S., Dobo J., Kjaer T.R., Sirotkina S., Yatime L., Sottrup-Jensen L., Thiel S., Gal P., Andersen G.R. Structural basis for activation of the complement system by component C4 cleavage. Proc Natl Acad Sci U S A 2012, 109:15425-15430.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 15425-15430
-
-
Kidmose, R.T.1
Laursen, N.S.2
Dobo, J.3
Kjaer, T.R.4
Sirotkina, S.5
Yatime, L.6
Sottrup-Jensen, L.7
Thiel, S.8
Gal, P.9
Andersen, G.R.10
-
38
-
-
84878407764
-
A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4
-
Perry A.J., Wijeyewickrema L.C., Wilmann P.G., Gunzburg M.J., D'Andrea L., Irving J.A., Pang S.S., Duncan R.C., Wilce J.A., Whisstock J.C., et al. A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4. J Biol Chem 2013, 288:15821-15829.
-
(2013)
J Biol Chem
, vol.288
, pp. 15821-15829
-
-
Perry, A.J.1
Wijeyewickrema, L.C.2
Wilmann, P.G.3
Gunzburg, M.J.4
D'Andrea, L.5
Irving, J.A.6
Pang, S.S.7
Duncan, R.C.8
Wilce, J.A.9
Whisstock, J.C.10
-
39
-
-
34247262583
-
Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway
-
Wallis R., Dodds A.W., Mitchell D.A., Sim R.B., Reid K.B., Schwaeble W.J. Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway. J Biol Chem 2007, 282:7844-7851.
-
(2007)
J Biol Chem
, vol.282
, pp. 7844-7851
-
-
Wallis, R.1
Dodds, A.W.2
Mitchell, D.A.3
Sim, R.B.4
Reid, K.B.5
Schwaeble, W.J.6
-
41
-
-
0034678903
-
Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle
-
Gaboriaud C., Rossi V., Bally I., Arlaud G.J., Fontecilla-Camps J.C. Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle. EMBO J 2000, 19:1755-1765.
-
(2000)
EMBO J
, vol.19
, pp. 1755-1765
-
-
Gaboriaud, C.1
Rossi, V.2
Bally, I.3
Arlaud, G.J.4
Fontecilla-Camps, J.C.5
-
42
-
-
0036850943
-
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
-
Budayova-Spano M., Grabarse W., Thielens N.M., Hillen H., Lacroix M., Schmidt M., Fontecilla-Camps J.C., Arlaud G.J., Gaboriaud C. Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism. Structure 2002, 10:1509-1519.
-
(2002)
Structure
, vol.10
, pp. 1509-1519
-
-
Budayova-Spano, M.1
Grabarse, W.2
Thielens, N.M.3
Hillen, H.4
Lacroix, M.5
Schmidt, M.6
Fontecilla-Camps, J.C.7
Arlaud, G.J.8
Gaboriaud, C.9
-
43
-
-
38949188247
-
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r
-
Kardos J., Harmat V., Pallo A., Barabas O., Szilagyi K., Graf L., Naray-Szabo G., Goto Y., Zavodszky P., Gal P. Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r. Mol Immunol 2008, 45:1752-1760.
-
(2008)
Mol Immunol
, vol.45
, pp. 1752-1760
-
-
Kardos, J.1
Harmat, V.2
Pallo, A.3
Barabas, O.4
Szilagyi, K.5
Graf, L.6
Naray-Szabo, G.7
Goto, Y.8
Zavodszky, P.9
Gal, P.10
-
44
-
-
0032477892
-
Solution structure of the epidermal growth factor (EGF)-like module of human complement protease C1r, an atypical member of the EGF family
-
Bersch B., Hernandez J.F., Marion D., Arlaud G.J. Solution structure of the epidermal growth factor (EGF)-like module of human complement protease C1r, an atypical member of the EGF family. Biochemistry 1998, 37:1204-1214.
-
(1998)
Biochemistry
, vol.37
, pp. 1204-1214
-
-
Bersch, B.1
Hernandez, J.F.2
Marion, D.3
Arlaud, G.J.4
-
45
-
-
80855128787
-
Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation
-
Gingras A.R., Girija U.V., Keeble A.H., Panchal R., Mitchell D.A., Moody P.C., Wallis R. Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation. Structure 2011, 19:1635-1643.
-
(2011)
Structure
, vol.19
, pp. 1635-1643
-
-
Gingras, A.R.1
Girija, U.V.2
Keeble, A.H.3
Panchal, R.4
Mitchell, D.A.5
Moody, P.C.6
Wallis, R.7
-
46
-
-
84862023318
-
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2
-
Heja D., Harmat V., Fodor K., Wilmanns M., Dobo J., Kekesi K.A., Zavodszky P., Gal P., Pal G. Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2. J Biol Chem 2012, 287:20290-20300.
-
(2012)
J Biol Chem
, vol.287
, pp. 20290-20300
-
-
Heja, D.1
Harmat, V.2
Fodor, K.3
Wilmanns, M.4
Dobo, J.5
Kekesi, K.A.6
Zavodszky, P.7
Gal, P.8
Pal, G.9
-
47
-
-
25844471033
-
A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations
-
Gal P., Harmat V., Kocsis A., Bian T., Barna L., Ambrus G., Vegh B., Balczer J., Sim R.B., Naray-Szabo G., et al. A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations. J Biol Chem 2005, 280:33435-33444.
-
(2005)
J Biol Chem
, vol.280
, pp. 33435-33444
-
-
Gal, P.1
Harmat, V.2
Kocsis, A.3
Bian, T.4
Barna, L.5
Ambrus, G.6
Vegh, B.7
Balczer, J.8
Sim, R.B.9
Naray-Szabo, G.10
-
48
-
-
4444375264
-
The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions
-
Harmat V., Gal P., Kardos J., Szilagyi K., Ambrus G., Vegh B., Naray-Szabo G., Zavodszky P. The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions. J Mol Biol 2004, 342:1533-1546.
-
(2004)
J Mol Biol
, vol.342
, pp. 1533-1546
-
-
Harmat, V.1
Gal, P.2
Kardos, J.3
Szilagyi, K.4
Ambrus, G.5
Vegh, B.6
Naray-Szabo, G.7
Zavodszky, P.8
-
49
-
-
33749265480
-
Structure of complement component C2A: implications for convertase formation and substrate binding
-
Milder F.J., Raaijmakers H.C., Vandeputte M.D., Schouten A., Huizinga E.G., Romijn R.A., Hemrika W., Roos A., Daha M.R., Gros P. Structure of complement component C2A: implications for convertase formation and substrate binding. Structure 2006, 14:1587-1597.
-
(2006)
Structure
, vol.14
, pp. 1587-1597
-
-
Milder, F.J.1
Raaijmakers, H.C.2
Vandeputte, M.D.3
Schouten, A.4
Huizinga, E.G.5
Romijn, R.A.6
Hemrika, W.7
Roos, A.8
Daha, M.R.9
Gros, P.10
-
50
-
-
61349200082
-
The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation
-
Krishnan V., Xu Y., Macon K., Volanakis J.E., Narayana S.V. The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation. Acta Crystallogr D Biol Crystallogr 2009, 65:266-274.
-
(2009)
Acta Crystallogr D Biol Crystallogr
, vol.65
, pp. 266-274
-
-
Krishnan, V.1
Xu, Y.2
Macon, K.3
Volanakis, J.E.4
Narayana, S.V.5
-
51
-
-
33847044475
-
The crystal structure of C2a, the catalytic fragment of classical pathway C3 and C5 convertase of human complement
-
Krishnan V., Xu Y., Macon K., Volanakis J.E., Narayana S.V. The crystal structure of C2a, the catalytic fragment of classical pathway C3 and C5 convertase of human complement. J Mol Biol 2007, 367:224-233.
-
(2007)
J Mol Biol
, vol.367
, pp. 224-233
-
-
Krishnan, V.1
Xu, Y.2
Macon, K.3
Volanakis, J.E.4
Narayana, S.V.5
|