메뉴 건너뛰기




Volumn 209, Issue 6, 2013, Pages 573.e1-573.e15

Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: An ex vivo study

Author keywords

BeWo; breast cancer resistance protein (BCRP); cannabidiol; human placental perfusion; Jar cells; marijuana

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CANNABIDIOL; GLIBENCLAMIDE; MITOXANTRONE; NICARDIPINE; PHENAZONE; XENOBIOTIC AGENT;

EID: 84888641390     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2013.08.005     Document Type: Article
Times cited : (61)

References (85)
  • 3
    • 84864003540 scopus 로고    scopus 로고
    • Risk factors for preterm birth in an international prospective cohort of nulliparous women
    • G.A. Dekker, S.Y. Lee, R.A. North, L.M. McCowan, N.A. Simpson, and C.T. Roberts Risk factors for preterm birth in an international prospective cohort of nulliparous women PLoS One 7 2012 e39154
    • (2012) PLoS One , vol.7 , pp. 39154
    • Dekker, G.A.1    Lee, S.Y.2    North, R.A.3    McCowan, L.M.4    Simpson, N.A.5    Roberts, C.T.6
  • 4
    • 84855955895 scopus 로고    scopus 로고
    • Birth outcomes associated with cannabis use before and during pregnancy
    • M.R. Hayatbakhsh, V.J. Flenady, and K.S. Gibbons Birth outcomes associated with cannabis use before and during pregnancy Pediatr Res 71 2012 215 219
    • (2012) Pediatr Res , vol.71 , pp. 215-219
    • Hayatbakhsh, M.R.1    Flenady, V.J.2    Gibbons, K.S.3
  • 5
    • 0035102559 scopus 로고    scopus 로고
    • Effects of prenatal exposure to marijuana
    • E. Kozer, and G. Koren Effects of prenatal exposure to marijuana Can Fam Physician 47 2001 263 264
    • (2001) Can Fam Physician , vol.47 , pp. 263-264
    • Kozer, E.1    Koren, G.2
  • 6
    • 84863730498 scopus 로고    scopus 로고
    • Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
    • A.R. Schier, N.P. Ribeiro, and A.C. Silva Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug Rev Bras Psiquiatr 34 Suppl 1 2012 104 110
    • (2012) Rev Bras Psiquiatr , vol.34 , Issue.SUPPL. 1 , pp. 104-110
    • Schier, A.R.1    Ribeiro, N.P.2    Silva, A.C.3
  • 8
    • 54249156391 scopus 로고    scopus 로고
    • Cannabidiol: From an inactive cannabinoid to a drug with wide spectrum of action
    • A.W. Zuardi Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action Rev Bras Psiquiatr 30 2008 271 280
    • (2008) Rev Bras Psiquiatr , vol.30 , pp. 271-280
    • Zuardi, A.W.1
  • 9
    • 84872142388 scopus 로고    scopus 로고
    • Medical use of cannabis. Cannabidiol: A new light for schizophrenia?
    • S. Deiana Medical use of cannabis. Cannabidiol: a new light for schizophrenia? Drug Test Anal 5 2013 46 51
    • (2013) Drug Test Anal , vol.5 , pp. 46-51
    • Deiana, S.1
  • 14
    • 0037207079 scopus 로고    scopus 로고
    • Cannabidiol: An overview of some chemical and pharmacological aspects. Part I: Chemical aspects
    • R. Mechoulam, and L. Hanus Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects Chem Phys Lipids 121 2002 35 43
    • (2002) Chem Phys Lipids , vol.121 , pp. 35-43
    • Mechoulam, R.1    Hanus, L.2
  • 15
    • 35648948415 scopus 로고    scopus 로고
    • The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids
    • M.L. Holland, D.T. Lau, J.D. Allen, and J.C. Arnold The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids Br J Pharmacol 152 2007 815 824
    • (2007) Br J Pharmacol , vol.152 , pp. 815-824
    • Holland, M.L.1    Lau, D.T.2    Allen, J.D.3    Arnold, J.C.4
  • 16
    • 33644828740 scopus 로고    scopus 로고
    • The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells
    • M.L. Holland, J.A. Panetta, and J.M. Hoskins The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells Biochem Pharmacol 71 2006 1146 1154
    • (2006) Biochem Pharmacol , vol.71 , pp. 1146-1154
    • Holland, M.L.1    Panetta, J.A.2    Hoskins, J.M.3
  • 17
    • 48749102177 scopus 로고    scopus 로고
    • Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1)
    • M.L. Holland, J.D. Allen, and J.C. Arnold Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1) Eur J Pharmacol 591 2008 128 131
    • (2008) Eur J Pharmacol , vol.591 , pp. 128-131
    • Holland, M.L.1    Allen, J.D.2    Arnold, J.C.3
  • 18
    • 77957221891 scopus 로고    scopus 로고
    • Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)
    • N. Tournier, L. Chevillard, B. Megarbane, S. Pirnay, J.M. Scherrmann, and X. Decleves Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) Int J Neuropsychopharmacol 13 2009 905 915
    • (2009) Int J Neuropsychopharmacol , vol.13 , pp. 905-915
    • Tournier, N.1    Chevillard, L.2    Megarbane, B.3    Pirnay, S.4    Scherrmann, J.M.5    Decleves, X.6
  • 19
    • 0032404092 scopus 로고    scopus 로고
    • A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
    • R. Allikmets, L.M. Schriml, A. Hutchinson, V. Romano-Spica, and M. Dean A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance Cancer Res 58 1998 5337 5339
    • (1998) Cancer Res , vol.58 , pp. 5337-5339
    • Allikmets, R.1    Schriml, L.M.2    Hutchinson, A.3    Romano-Spica, V.4    Dean, M.5
  • 20
    • 33748413464 scopus 로고    scopus 로고
    • P-glycoprotein in the placenta: Expression, localization, regulation and function
    • M. Ceckova-Novotna, P. Pavek, and F. Staud P-glycoprotein in the placenta: expression, localization, regulation and function Reprod Toxicol 22 2006 400 410
    • (2006) Reprod Toxicol , vol.22 , pp. 400-410
    • Ceckova-Novotna, M.1    Pavek, P.2    Staud, F.3
  • 22
    • 43049104121 scopus 로고    scopus 로고
    • BCRP/ABCG2 in the placenta: Expression, function and regulation
    • Q. Mao BCRP/ABCG2 in the placenta: expression, function and regulation Pharm Res 25 2008 1244 1255
    • (2008) Pharm Res , vol.25 , pp. 1244-1255
    • Mao, Q.1
  • 23
    • 77958508112 scopus 로고    scopus 로고
    • ABCB1 and ABCG2 expression in the placenta and fetus: An interspecies comparison
    • P. Myllynen, M. Kummu, and E. Sieppi ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparison Expert Opin Drug Metab Toxicol 6 2010 1385 1398
    • (2010) Expert Opin Drug Metab Toxicol , vol.6 , pp. 1385-1398
    • Myllynen, P.1    Kummu, M.2    Sieppi, E.3
  • 24
    • 79953803082 scopus 로고    scopus 로고
    • ATP-binding cassette efflux transporters in human placenta
    • Z. Ni, and Q. Mao ATP-binding cassette efflux transporters in human placenta Curr Pharm Biotechnol 12 2011 674 685
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 674-685
    • Ni, Z.1    Mao, Q.2
  • 26
    • 70350053125 scopus 로고    scopus 로고
    • Drug transporters in the human blood-placental barrier
    • K. Vahakangas, and P. Myllynen Drug transporters in the human blood-placental barrier Br J Pharmacol 158 2009 665 678
    • (2009) Br J Pharmacol , vol.158 , pp. 665-678
    • Vahakangas, K.1    Myllynen, P.2
  • 27
    • 47349110179 scopus 로고    scopus 로고
    • Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
    • S.F. Zhou Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition Xenobiotica 38 2008 802 832
    • (2008) Xenobiotica , vol.38 , pp. 802-832
    • Zhou, S.F.1
  • 28
    • 35948966011 scopus 로고    scopus 로고
    • The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction
    • D.A. Evseenko, P. Murthi, and J.W. Paxton The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction Faseb J 21 2007 3592 3605
    • (2007) Faseb J , vol.21 , pp. 3592-3605
    • Evseenko, D.A.1    Murthi, P.2    Paxton, J.W.3
  • 29
    • 33947731105 scopus 로고    scopus 로고
    • The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells
    • D.A. Evseenko, J.W. Paxton, and J.A. Keelan The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells Placenta 28 Suppl A 2007 S116 S120
    • (2007) Placenta , vol.28 , Issue.SUPPL. A
    • Evseenko, D.A.1    Paxton, J.W.2    Keelan, J.A.3
  • 30
    • 24744434119 scopus 로고    scopus 로고
    • The ABC transporter Abcg2/Bcrp: Role in hypoxia mediated survival
    • P. Krishnamurthy, and J.D. Schuetz The ABC transporter Abcg2/Bcrp: role in hypoxia mediated survival Biometals 18 2005 349 358
    • (2005) Biometals , vol.18 , pp. 349-358
    • Krishnamurthy, P.1    Schuetz, J.D.2
  • 31
    • 79955604531 scopus 로고    scopus 로고
    • Assessing drug transport across the human placental barrier: From in vivo and in vitro measurements to the ex vivo perfusion method and in silico techniques
    • C. Giaginis, A. Tsantili-Kakoulidou, and S. Theocharis Assessing drug transport across the human placental barrier: from in vivo and in vitro measurements to the ex vivo perfusion method and in silico techniques Curr Pharm Biotechnol 12 2011 804 813
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 804-813
    • Giaginis, C.1    Tsantili-Kakoulidou, A.2    Theocharis, S.3
  • 32
    • 35648954071 scopus 로고    scopus 로고
    • The human placenta - An alternative for studying foetal exposure
    • M. Myren, T. Mose, L. Mathiesen, and L.E. Knudsen The human placenta - an alternative for studying foetal exposure Toxicol In Vitro 21 2007 1332 1340
    • (2007) Toxicol in Vitro , vol.21 , pp. 1332-1340
    • Myren, M.1    Mose, T.2    Mathiesen, L.3    Knudsen, L.E.4
  • 33
    • 50249171227 scopus 로고    scopus 로고
    • Neutral red uptake assay for the estimation of cell viability/ cytotoxicity
    • G. Repetto, A. del Peso, and J.L. Zurita Neutral red uptake assay for the estimation of cell viability/cytotoxicity Nat Protoc 3 2008 1125 1131
    • (2008) Nat Protoc , vol.3 , pp. 1125-1131
    • Repetto, G.1    Del Peso, A.2    Zurita, J.L.3
  • 34
    • 0347130864 scopus 로고    scopus 로고
    • Cell size and water permeability as determining factors for cell viability after freezing at different cooling rates
    • F. Dumont, P.A. Marechal, and P. Gervais Cell size and water permeability as determining factors for cell viability after freezing at different cooling rates Appl Environ Microbiol 70 2004 268 272
    • (2004) Appl Environ Microbiol , vol.70 , pp. 268-272
    • Dumont, F.1    Marechal, P.A.2    Gervais, P.3
  • 35
    • 5444270872 scopus 로고    scopus 로고
    • EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis
    • A. Mittal, M.S. Pate, R.C. Wylie, T.O. Tollefsbol, and S.K. Katiyar EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis Int J Oncol 24 2004 703 710
    • (2004) Int J Oncol , vol.24 , pp. 703-710
    • Mittal, A.1    Pate, M.S.2    Wylie, R.C.3    Tollefsbol, T.O.4    Katiyar, S.K.5
  • 36
    • 77953651113 scopus 로고    scopus 로고
    • Nitrofurantoin transport by placental choriocarcinoma JAr cells: Involvement of BCRP, OATP2B1 and other MDR transporters
    • V. Feinshtein, G. Holcberg, and A. Amash Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters Arch Gynecol Obstet 281 2010 1037 1044
    • (2010) Arch Gynecol Obstet , vol.281 , pp. 1037-1044
    • Feinshtein, V.1    Holcberg, G.2    Amash, A.3
  • 37
    • 77249178904 scopus 로고    scopus 로고
    • Antidepressants increase beta-arrestin2 ubiquitinylation and degradation by the proteasomal pathway in C6 rat glioma cells
    • M. Golan, G. Schreiber, and S. Avissar Antidepressants increase beta-arrestin2 ubiquitinylation and degradation by the proteasomal pathway in C6 rat glioma cells J Pharmacol Exp Ther 332 2009 970 976
    • (2009) J Pharmacol Exp Ther , vol.332 , pp. 970-976
    • Golan, M.1    Schreiber, G.2    Avissar, S.3
  • 38
    • 84866075641 scopus 로고    scopus 로고
    • CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells
    • J.C. Arnold, P. Hone, M.L. Holland, and J.D. Allen CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells Pharmacol Rep 64 2012 751 757
    • (2012) Pharmacol Rep , vol.64 , pp. 751-757
    • Arnold, J.C.1    Hone, P.2    Holland, M.L.3    Allen, J.D.4
  • 39
    • 84875928552 scopus 로고    scopus 로고
    • The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig
    • A. Dudasova, S.D. Keir, M.E. Parsons, A. Molleman, and C.P. Page The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig Pulm Pharmacol Ther 26 2013 373 379
    • (2013) Pulm Pharmacol Ther , vol.26 , pp. 373-379
    • Dudasova, A.1    Keir, S.D.2    Parsons, M.E.3    Molleman, A.4    Page, C.P.5
  • 40
    • 84855998880 scopus 로고    scopus 로고
    • Contrasting protective effects of cannabinoids against oxidative stress and amyloid-beta evoked neurotoxicity in vitro
    • B.S. Harvey, K.S. Ohlsson, J.L. Maag, I.F. Musgrave, and S.D. Smid Contrasting protective effects of cannabinoids against oxidative stress and amyloid-beta evoked neurotoxicity in vitro Neurotoxicology 33 2012 138 146
    • (2012) Neurotoxicology , vol.33 , pp. 138-146
    • Harvey, B.S.1    Ohlsson, K.S.2    Maag, J.L.3    Musgrave, I.F.4    Smid, S.D.5
  • 42
    • 84876556444 scopus 로고    scopus 로고
    • Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells
    • A. Juknat, M. Pietr, and E. Kozela Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells PLoS One 8 2013 e61462
    • (2013) PLoS One , vol.8 , pp. 61462
    • Juknat, A.1    Pietr, M.2    Kozela, E.3
  • 43
    • 33747624175 scopus 로고    scopus 로고
    • Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
    • A. Ligresti, A.S. Moriello, and K. Starowicz Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma J Pharmacol Exp Ther 318 2006 1375 1387
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 1375-1387
    • Ligresti, A.1    Moriello, A.S.2    Starowicz, K.3
  • 44
    • 84875520814 scopus 로고    scopus 로고
    • Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium
    • Y. Maor, J. Yu, P.M. Kuzontkoski, B.J. Dezube, X. Zhang, and J.E. Groopman Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium Genes Cancer 3 2012 512 520
    • (2012) Genes Cancer , vol.3 , pp. 512-520
    • Maor, Y.1    Yu, J.2    Kuzontkoski, P.M.3    Dezube, B.J.4    Zhang, X.5    Groopman, J.E.6
  • 45
    • 84872128254 scopus 로고    scopus 로고
    • Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
    • M. Nabissi, M.B. Morelli, M. Santoni, and G. Santoni Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents Carcinogenesis 34 2013 48 57
    • (2013) Carcinogenesis , vol.34 , pp. 48-57
    • Nabissi, M.1    Morelli, M.B.2    Santoni, M.3    Santoni, G.4
  • 46
    • 33645841349 scopus 로고    scopus 로고
    • Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana
    • H.J. Zhu, J.S. Wang, and J.S. Markowitz Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana J Pharmacol Exp Ther 317 2006 850 857
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 850-857
    • Zhu, H.J.1    Wang, J.S.2    Markowitz, J.S.3
  • 47
    • 82755165068 scopus 로고    scopus 로고
    • Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis
    • D. De Filippis, G. Esposito, and C. Cirillo Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis PLoS One 6 2011 e28159
    • (2011) PLoS One , vol.6 , pp. 28159
    • De Filippis, D.1    Esposito, G.2    Cirillo, C.3
  • 48
    • 84867803387 scopus 로고    scopus 로고
    • Cannabidiol inhibits angiogenesis by multiple mechanisms
    • M. Solinas, P. Massi, and A.R. Cantelmo Cannabidiol inhibits angiogenesis by multiple mechanisms Br J Pharmacol 167 2012 1218 1231
    • (2012) Br J Pharmacol , vol.167 , pp. 1218-1231
    • Solinas, M.1    Massi, P.2    Cantelmo, A.R.3
  • 49
    • 84866113326 scopus 로고    scopus 로고
    • Cadmium inhibits ABCG2 transporter function in BeWo choriocarcinoma cells and MCF-7 cells overexpressing ABCG2
    • M. Kummu, E. Sieppi, K. Wallin, A. Rautio, K. Vahakangas, and P. Myllynen Cadmium inhibits ABCG2 transporter function in BeWo choriocarcinoma cells and MCF-7 cells overexpressing ABCG2 Placenta 33 2012 859 865
    • (2012) Placenta , vol.33 , pp. 859-865
    • Kummu, M.1    Sieppi, E.2    Wallin, K.3    Rautio, A.4    Vahakangas, K.5    Myllynen, P.6
  • 51
    • 84866278626 scopus 로고    scopus 로고
    • Placental secretion of interleukin-1 and interleukin-1 receptor antagonist in preeclampsia: Effect of magnesium sulfate
    • A. Amash, G. Holcberg, O. Sapir, and M. Huleihel Placental secretion of interleukin-1 and interleukin-1 receptor antagonist in preeclampsia: effect of magnesium sulfate J Interferon Cytokine Res 32 2012 432 441
    • (2012) J Interferon Cytokine Res , vol.32 , pp. 432-441
    • Amash, A.1    Holcberg, G.2    Sapir, O.3    Huleihel, M.4
  • 52
    • 49049111564 scopus 로고    scopus 로고
    • The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta
    • E. Pollex, A. Lubetsky, and G. Koren The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta Placenta 29 2008 743 747
    • (2008) Placenta , vol.29 , pp. 743-747
    • Pollex, E.1    Lubetsky, A.2    Koren, G.3
  • 53
    • 0035735070 scopus 로고    scopus 로고
    • A novel extractionless hplc fluorescence method for the determination of glyburide in the human plasma: Application to a bioequivalence study
    • J. Khatri, S. Qassim, O. Abed, B. Abraham, A. Al-Lami, and S. Masood A novel extractionless hplc fluorescence method for the determination of glyburide in the human plasma: application to a bioequivalence study J Pharm Pharm Sci 4 2001 201 206
    • (2001) J Pharm Pharm Sci , vol.4 , pp. 201-206
    • Khatri, J.1    Qassim, S.2    Abed, O.3    Abraham, B.4    Al-Lami, A.5    Masood, S.6
  • 54
    • 79955866458 scopus 로고    scopus 로고
    • During pregnancy, recreational drug-using women stop taking ecstasy (3,4-methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: Initial findings from the Development and Infancy Study
    • [Epub ahead of print]
    • D.G. Moore, J.D. Turner, and A.C. Parrott During pregnancy, recreational drug-using women stop taking ecstasy (3,4-methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: initial findings from the Development and Infancy Study J Psychopharmacol 2009 [Epub ahead of print]
    • (2009) J Psychopharmacol
    • Moore, D.G.1    Turner, J.D.2    Parrott, A.C.3
  • 55
    • 77953020144 scopus 로고    scopus 로고
    • Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study
    • M.M. van Gelder, J. Reefhuis, A.R. Caton, M.M. Werler, C.M. Druschel, and N. Roeleveld Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study Drug Alcohol Depend 109 2010 243 247
    • (2010) Drug Alcohol Depend , vol.109 , pp. 243-247
    • Van Gelder, M.M.1    Reefhuis, J.2    Caton, A.R.3    Werler, M.M.4    Druschel, C.M.5    Roeleveld, N.6
  • 56
    • 84873414442 scopus 로고    scopus 로고
    • Smoking and marijuana use in pregnancy
    • H.L. Brown, and C.R. Graves Smoking and marijuana use in pregnancy Clin Obstet Gynecol 56 2013 107 113
    • (2013) Clin Obstet Gynecol , vol.56 , pp. 107-113
    • Brown, H.L.1    Graves, C.R.2
  • 57
    • 0036362325 scopus 로고    scopus 로고
    • Maternal use of cannabis and pregnancy outcome
    • D.M. Fergusson, L.J. Horwood, and K. Northstone Maternal use of cannabis and pregnancy outcome BJOG 109 2002 21 27
    • (2002) BJOG , vol.109 , pp. 21-27
    • Fergusson, D.M.1    Horwood, L.J.2    Northstone, K.3
  • 58
    • 0021262985 scopus 로고
    • Marijuana use during pregnancy and decreased length of gestation
    • P.A. Fried, B. Watkinson, and A. Willan Marijuana use during pregnancy and decreased length of gestation Am J Obstet Gynecol 150 1984 23 27
    • (1984) Am J Obstet Gynecol , vol.150 , pp. 23-27
    • Fried, P.A.1    Watkinson, B.2    Willan, A.3
  • 59
    • 84857095085 scopus 로고    scopus 로고
    • Prenatal tobacco, marijuana, stimulant, and opiate exposure: Outcomes and practice implications
    • S. Minnes, A. Lang, and L. Singer Prenatal tobacco, marijuana, stimulant, and opiate exposure: outcomes and practice implications Addict Sci Clin Pract 6 2011 57 70
    • (2011) Addict Sci Clin Pract , vol.6 , pp. 57-70
    • Minnes, S.1    Lang, A.2    Singer, L.3
  • 60
    • 48749085911 scopus 로고    scopus 로고
    • Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse
    • J.R. Araujo, P. Goncalves, and F. Martel Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse J Biochem 144 2008 177 186
    • (2008) J Biochem , vol.144 , pp. 177-186
    • Araujo, J.R.1    Goncalves, P.2    Martel, F.3
  • 61
    • 58149470222 scopus 로고    scopus 로고
    • Effect of cannabinoids upon the uptake of folic acid by BeWo cells
    • J.R. Araujo, P. Goncalves, and F. Martel Effect of cannabinoids upon the uptake of folic acid by BeWo cells Pharmacology 83 2009 170 176
    • (2009) Pharmacology , vol.83 , pp. 170-176
    • Araujo, J.R.1    Goncalves, P.2    Martel, F.3
  • 62
    • 53249103459 scopus 로고    scopus 로고
    • Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation
    • O.M. Habayeb, A.H. Taylor, S.C. Bell, D.J. Taylor, and J.C. Konje Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation Endocrinology 149 2008 5052 5060
    • (2008) Endocrinology , vol.149 , pp. 5052-5060
    • Habayeb, O.M.1    Taylor, A.H.2    Bell, S.C.3    Taylor, D.J.4    Konje, J.C.5
  • 63
    • 40749117230 scopus 로고    scopus 로고
    • Plasma anandamide concentration and pregnancy outcome in women with threatened miscarriage
    • O.M. Habayeb, A.H. Taylor, M. Finney, M.D. Evans, and J.C. Konje Plasma anandamide concentration and pregnancy outcome in women with threatened miscarriage JAMA 299 2008 1135 1136
    • (2008) JAMA , vol.299 , pp. 1135-1136
    • Habayeb, O.M.1    Taylor, A.H.2    Finney, M.3    Evans, M.D.4    Konje, J.C.5
  • 64
    • 0032857273 scopus 로고    scopus 로고
    • Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta
    • S.P. Kenney, R. Kekuda, P.D. Prasad, F.H. Leibach, L.D. Devoe, and V. Ganapathy Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta Am J Obstet Gynecol 181 1999 491 497
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 491-497
    • Kenney, S.P.1    Kekuda, R.2    Prasad, P.D.3    Leibach, F.H.4    Devoe, L.D.5    Ganapathy, V.6
  • 65
    • 33744779064 scopus 로고    scopus 로고
    • Delta9-tetrahydrocannabinol inhibits cytotrophoblast cell proliferation and modulates gene transcription
    • M. Khare, A.H. Taylor, J.C. Konje, and S.C. Bell Delta9- tetrahydrocannabinol inhibits cytotrophoblast cell proliferation and modulates gene transcription Mol Hum Reprod 12 2006 321 333
    • (2006) Mol Hum Reprod , vol.12 , pp. 321-333
    • Khare, M.1    Taylor, A.H.2    Konje, J.C.3    Bell, S.C.4
  • 66
    • 84861677799 scopus 로고    scopus 로고
    • Feto-placental morphological effects of prenatal exposure to drugs of abuse
    • S. Ortigosa, B. Friguls, and X. Joya Feto-placental morphological effects of prenatal exposure to drugs of abuse Reprod Toxicol 34 2012 73 79
    • (2012) Reprod Toxicol , vol.34 , pp. 73-79
    • Ortigosa, S.1    Friguls, B.2    Joya, X.3
  • 67
    • 0032493378 scopus 로고    scopus 로고
    • The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation
    • L. De Petrocellis, D. Melck, and A. Palmisano The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation Proc Natl Acad Sci U S A 95 1998 8375 8380
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8375-8380
    • De Petrocellis, L.1    Melck, D.2    Palmisano, A.3
  • 68
    • 0942276562 scopus 로고    scopus 로고
    • Identification of the CB1 cannabinoid receptor and fatty acid amide hydrolase (FAAH) in the human placenta
    • B. Park, H.M. Gibbons, M.D. Mitchell, and M. Glass Identification of the CB1 cannabinoid receptor and fatty acid amide hydrolase (FAAH) in the human placenta Placenta 24 2003 990 995
    • (2003) Placenta , vol.24 , pp. 990-995
    • Park, B.1    Gibbons, H.M.2    Mitchell, M.D.3    Glass, M.4
  • 69
    • 77953651113 scopus 로고    scopus 로고
    • Nitrofurantoin transport by placental choriocarcinoma JAr cells: Involvement of BCRP, OATP2B1 and other MDR transporters
    • V. Feinshtein, G. Holcberg, and A. Amash Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters Arch Gynecol Obstet 281 2010 1037 1044
    • (2010) Arch Gynecol Obstet , vol.281 , pp. 1037-1044
    • Feinshtein, V.1    Holcberg, G.2    Amash, A.3
  • 70
    • 72749105408 scopus 로고    scopus 로고
    • The safety of H(2)-blockers use during pregnancy
    • I. Matok, R. Gorodischer, and G. Koren The safety of H(2)-blockers use during pregnancy J Clin Pharmacol 50 2010 81 87
    • (2010) J Clin Pharmacol , vol.50 , pp. 81-87
    • Matok, I.1    Gorodischer, R.2    Koren, G.3
  • 71
    • 84873867412 scopus 로고    scopus 로고
    • Neonatal outcomes after gestational exposure to nitrofurantoin
    • H. Nordeng, A. Lupattelli, M. Romoren, and G. Koren Neonatal outcomes after gestational exposure to nitrofurantoin Obstet Gynecol 121 2013 306 313
    • (2013) Obstet Gynecol , vol.121 , pp. 306-313
    • Nordeng, H.1    Lupattelli, A.2    Romoren, M.3    Koren, G.4
  • 72
    • 84879089013 scopus 로고    scopus 로고
    • How safe are anti-rheumatic drugs during pregnancy?
    • M. Ostensen, and F. Forger How safe are anti-rheumatic drugs during pregnancy? Curr Opin Pharmacol 13 2013 470 475
    • (2013) Curr Opin Pharmacol , vol.13 , pp. 470-475
    • Ostensen, M.1    Forger, F.2
  • 73
    • 11844284860 scopus 로고    scopus 로고
    • Human breast cancer resistance protein: Interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine, and transport of cimetidine
    • P. Pavek, G. Merino, and E. Wagenaar Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine, and transport of cimetidine J Pharmacol Exp Ther 312 2005 144 152
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 144-152
    • Pavek, P.1    Merino, G.2    Wagenaar, E.3
  • 74
    • 84874600093 scopus 로고    scopus 로고
    • Studies on the intestinal absorption characteristics of sulfasalazine, a breast cancer resistance protein (BCRP) substrate
    • A. Tomaru, N. Morimoto, and M. Morishita Studies on the intestinal absorption characteristics of sulfasalazine, a breast cancer resistance protein (BCRP) substrate Drug Metab Pharmacokinet 28 2013 71 74
    • (2013) Drug Metab Pharmacokinet , vol.28 , pp. 71-74
    • Tomaru, A.1    Morimoto, N.2    Morishita, M.3
  • 76
    • 36348932850 scopus 로고    scopus 로고
    • Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoin in the pregnant mouse
    • Y. Zhang, H. Wang, J.D. Unadkat, and Q. Mao Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoin in the pregnant mouse Drug Metab Dispos 35 2007 2154 2158
    • (2007) Drug Metab Dispos , vol.35 , pp. 2154-2158
    • Zhang, Y.1    Wang, H.2    Unadkat, J.D.3    Mao, Q.4
  • 77
    • 0035003363 scopus 로고    scopus 로고
    • The pharmacokinetics of THC in fat and brain: Resulting functional responses to marihuana smoking
    • G.G. Nahas The pharmacokinetics of THC in fat and brain: resulting functional responses to marihuana smoking Hum Psychopharmacol 16 2001 247 255
    • (2001) Hum Psychopharmacol , vol.16 , pp. 247-255
    • Nahas, G.G.1
  • 78
    • 0035138027 scopus 로고    scopus 로고
    • Pharmacology and effects of cannabis: A brief review
    • C.H. Ashton Pharmacology and effects of cannabis: a brief review Br J Psychiatry 178 2001 101 106
    • (2001) Br J Psychiatry , vol.178 , pp. 101-106
    • Ashton, C.H.1
  • 79
    • 33645851325 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract
    • T. Nadulski, F. Pragst, and G. Weinberg Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract Ther Drug Monit 27 2005 799 810
    • (2005) Ther Drug Monit , vol.27 , pp. 799-810
    • Nadulski, T.1    Pragst, F.2    Weinberg, G.3
  • 80
    • 39049124647 scopus 로고    scopus 로고
    • Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: Implications for psychoactivity and pharmacology
    • D.J. Potter, P. Clark, and M.B. Brown Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology J. Forensic Sci 53 2008 90 94
    • (2008) J. Forensic Sci , vol.53 , pp. 90-94
    • Potter, D.J.1    Clark, P.2    Brown, M.B.3
  • 81
    • 61349100167 scopus 로고    scopus 로고
    • Does oestrogen allow women to store fat more efficiently? A biological advantage for fertility and gestation
    • A.J. O'Sullivan Does oestrogen allow women to store fat more efficiently? A biological advantage for fertility and gestation Obes Rev 10 2009 168 177
    • (2009) Obes Rev , vol.10 , pp. 168-177
    • O'Sullivan, A.J.1
  • 82
    • 70350489840 scopus 로고    scopus 로고
    • Implications of plasma Delta9-tetrahydrocannabinol, 11-hydroxy-THC, and 11-nor-9-carboxy-THC concentrations in chronic cannabis smokers
    • E.L. Karschner, E.W. Schwilke, and R.H. Lowe Implications of plasma Delta9-tetrahydrocannabinol, 11-hydroxy-THC, and 11-nor-9-carboxy-THC concentrations in chronic cannabis smokers J Anal Toxicol 33 2009 469 477
    • (2009) J Anal Toxicol , vol.33 , pp. 469-477
    • Karschner, E.L.1    Schwilke, E.W.2    Lowe, R.H.3
  • 83
    • 52049095040 scopus 로고    scopus 로고
    • ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in perfused term human placenta
    • P. Myllynen, M. Kummu, and T. Kangas ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in perfused term human placenta Toxicol Appl Pharmacol 232 2008 210 217
    • (2008) Toxicol Appl Pharmacol , vol.232 , pp. 210-217
    • Myllynen, P.1    Kummu, M.2    Kangas, T.3
  • 84
    • 0038691604 scopus 로고    scopus 로고
    • Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro
    • G. Holcberg, O. Sapir, and M. Tsadkin Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro Eur J Obstet Gynecol Reprod Biol 109 2003 133 137
    • (2003) Eur J Obstet Gynecol Reprod Biol , vol.109 , pp. 133-137
    • Holcberg, G.1    Sapir, O.2    Tsadkin, M.3
  • 85
    • 0021894944 scopus 로고
    • Dual in vitro perfusion of an isolated lobe of human placenta: Method and instrumentation
    • H. Schneider, and A. Huch Dual in vitro perfusion of an isolated lobe of human placenta:method and instrumentation Contrib Gynecol Obstet 13 1985 40 47
    • (1985) Contrib Gynecol Obstet , vol.13 , pp. 40-47
    • Schneider, H.1    Huch, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.