The pharmacokinetics of THC in fat and brain: Resulting functional responses to marihuana smoking

Human Psychopharmacology

Volumn 16, Issue 3, 2001, Pages 247-255

  Nahas, Gabriel G ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

7TM receptor; Blood brain barrier; Heart rate; Lipid bilayer; Marihuana; Molecular transmission; Pharmacokinetics; Pleasant sensory perception (PSP); THC; Xenobiotics GPCR

Indexed keywords

CANNABIS; MEMBRANE RECEPTOR; TETRAHYDROCANNABINOL; XENOBIOTIC AGENT;

ADIPOSE TISSUE; ADULT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG EXPOSURE; DRUG RESPONSE; DRUG SOLUBILITY; DRUG STORAGE; DRUG UPTAKE; FEMALE; HEART RATE; HUMAN; LIPID BILAYER; MALE; NEUROPROTECTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SMOKING; TIME;

EID: 0035003363     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/hup.258     Document Type: Article

References (17)

1. On the metabolism of tritium-labelled 1-tetrahydrocannabinol in the rabbit
2. Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man
3. Distribution and disposition of delta-9 tetrahydrocannabinol (THC) in different tissues of the rat
4. Towards a cannabinoid hypothesis of schizophrenia: Cognitive impairments due to dysregulation of the endogenous cannabinoid system
5. Does general anesthetic-induced desensitization of the Torpedo acetylcholine receptor correlate with lipid disordering?
6. Pharmacokinetics and disposition of delta-9 THC and its metabolites
7. Chemistry, metabolism, and pharmacokinetics of the cannabinoids
8. Do plasma concentrations of delta 9-tetrahydrocannabinol reflect the degree of intoxication?
9. Pharmacokinetics of THC in inhaled and oral preparations
10. Delta-9-tetrahydrocannabinol: Localization in body fat
11. Marihuana: Studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man
12. The kinetics of cannabinoid distribution and storage with special reference to the brain and testis
13. Psychoactive cannabinoids and membrane signaling
14. The psychologic and physiologic effects of active cannabinoids
15. Marijuana: Standardized smoke administration and dose effect curves on heart rate in humans
16. A unitary theory of anesthesia based on lateral phase separations in nerve membranes