Estimation and partition of heritability in human populations using whole-genome analysis methods

Annual Review of Genetics

Volumn 47, Issue , 2013, Pages 75-95

  Vinkhuyzen, Anna A E ^a   Wray, Naomi R ^a   Yang, Jian ^a,b   Goddard, Michael E ^c,d   Visscher, Peter M ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b TRANSLATIONAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d DEPARTMENT OF PRIMARY INDUSTRIES   (Australia)

Author keywords

Additive genetic variance; Genetic architecture; Genomic relationship; Mixed linear model; Quantitative traits; Whole genome methods

Indexed keywords

BODY HEIGHT; DIAGNOSTIC ACCURACY; DIZYGOTIC TWINS; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENOME ANALYSIS; HERITABILITY; HUMAN; INTERMETHOD COMPARISON; METHODOLOGY; MIXED LINEAR MODEL; MONOZYGOTIC TWINS; PEDIGREE ANALYSIS; PHENOTYPIC VARIATION; POPULATION GENETICS; PRIORITY JOURNAL; QUANTITATIVE GENETICS; RELATIVE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

BODY HEIGHT; FAMILY; GENETIC VARIATION; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINEAR MODELS; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; PEDIGREE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE; RESEARCH DESIGN; SAMPLE SIZE; SEQUENCE ANALYSIS, DNA; SIBLINGS; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 84888587567     PISSN: 00664197     EISSN: 15452948     Source Type: Book Series    
DOI: 10.1146/annurev-genet-111212-133258     Document Type: Review

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