The genetics of haemostasis: A twin study

Lancet

Volumn 357, Issue 9250, 2001, Pages 101-105

  De Lange, Marlies ^a   Snieder, Harold ^a   Ariëns, Robert A S ^b   Spector, Tim D ^a   Grant, Peter J ^b  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; FIBRINOGEN; KALLIKREIN; KININ; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; BLOOD CLOTTING; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; COMPLEMENT SYSTEM; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; FEMALE; FIBRINOLYSIS; GENETIC ANALYSIS; GENETIC MODEL; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HEMOSTASIS; HERITABILITY; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MONOZYGOTIC TWINS; PRIORITY JOURNAL;

EID: 0035852473     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)03541-8     Document Type: Article

References (34)

1. Coronary risk associated with age and sex of parental heart disease in the Framingham Study
2. Genetic susceptibility to death from coronary heart disease in a study of twins
3. Fibrinogen and risk of cardiovascular disease: The Framingham Study
4. Haemostatic function and ischaemic heart disease: Principal results of the Northwick Park Heart Study
5. Endogenous tissue-type plasminogen activator and risk of myocardial infarction
6. Fibrin D-dimer, tissue plasminogen activator, plasminogen activator inhibitor, and the risk of major ischaemic heart disease in the Caerphilly Study
7. Plasminogen activator inhibitor in plasma: Risk for recurrent myocardial infarction
8. Genetic and cultural inheritance of plasma fibrinogen concentration
9. Genetic and environmental sources of fibrogen variability in Israeli families: The Kibbutz family study
10. Moderate genetic influences on plasma levels of plasminogen activator inhibitor-1 and evidence of genetic and environmental influences shared by plasminogen activator inhibitor-1, triglycerides, and body mass index
11. Genetic effects for plasma factor VIIa levels independent of and in common with triglycerides
12. Determinants of plasma levels of plasminogen activator inhibitor-1: A study of normotensive twins
13. Factor VIII and factor IX in a twin population: Evidence for a major effect of ABO locus on factor VIII level
14. Von Willebrand factor and factor VIII:c in acute cerebrovascular disease; relationship to stroke subtype and mortality
15. Gerinnungsphysiologische schnellmethode zur bestimmung des fibrinogens
16. Levels of activated FXII in survivors of myocardial infarction: Association with circulating risk factors and extent of coronary artery disease
17. Role of haemostatic gene sequence polymorphisms in venous and arterial disease
18. Subunit antigen and activity levels of blood coagulation factor XIII in healthy individuals: Relation to gender, age, smoking and hypertension
19. A common coding polymorphism in the factor XIII A-subunit gene (factor XIII Val34Leu) affects cross-linking activity
20. Metabolic determinants are much more important than genetic polymorphisms in determining the PAI-1 activity and antigen plasma concentrations: A family study with part of the Stanislas Cohort
21. Five frequent polymorphisms of the PAI-1 gene: Lack of association between genotypes, PAI activity, and triglyceride levels in a healthy population
22. The 4G/5G genetic polymorphism in the promotor of the plasminogen activator inhibitor-1 (PAI-I) gene is associated with differences in plasma PAI-1 activity but not with risk of myocardial infarction in the ECTIM study
23. Plasminogen activator inhibitor-1 (PAI-1) promotor 4G/5G genotype and levels in relation to a history of myocardial infarction in patients characterised by coronary angiography
24. Factor VII gene polymorphisms contribute about one third of the factor VII level variation in plasma
25. Analysis of the F8 gene in individuals with high plasma factor VIII:C levels and associated venous thrombosis
26. Variation of the von Willebrand factor (vWF) gene locus is associated with plasma vWF:Ag levels: Identification of three novel single nucleotide polymorphisms in the vWF gene promoter
27. Von Willebrand disease
28. The factor XIII Val34Leu polymorphism accelerates thrombin activation of factor XIII and affects crosslinked fibrin structure
29. The physiology and biochemistry of factor XIII
30. Relation of fetal and infant growth to plasma fibrinogen and factor VII concentrations in adult life
31. FXII (46C->T) polymorphism and in vivo generation of FXII activity: Gene frequencies and relationship in patients with coronary artery disease
32. Twins; novel uses to study complex traits and genetic diseases
33. Genetic influences on F cells and other hematologic variables: A twin heritability study