Inhibition of protein glycation by procyanidin-B2 enriched fraction of cinnamon: Delay of diabetic cataract in rats

IUBMB Life

Volumn 65, Issue 11, 2013, Pages 941-950

  Muthenna, Puppala ^a   Raghu, Ganugula ^a   Akileshwari, Chandrasekhar ^a   Sinha, Sukesh Narayana ^a   Suryanarayana, Palla ^a   Reddy, Geereddy Bhanuprakash ^a  

^a NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

advanced glycation end products; cinnamon; diabetic cataract; lens proteins; procyanidin B2; protein glycation

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CINNAMON EXTRACT; GLUCONOLACTONE; HEMOGLOBIN A1C; LENS PROTEIN; PROCYANIDIN B2; UNCLASSIFIED DRUG; BIFLAVONOID; CATECHIN; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; PLANT EXTRACT; PROANTHOCYANIDIN;

ANIMAL EXPERIMENT; ARTICLE; CATARACT; CINNAMON; CONTROLLED STUDY; EX VIVO STUDY; FLUORESCENCE; GLUCOSE BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNODETECTION; LENS; MALE; NONHUMAN; PROTEIN GLYCOSYLATION; RAT; SLIT LAMP; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CINNAMOMUM ZEYLANICUM; DIABETES COMPLICATIONS; EXPERIMENTAL DIABETES MELLITUS; GLYCOSYLATION; HUMAN; METABOLISM; WISTAR RAT;

CINNAMOMUM VERUM; RATTUS;

ANIMALS; BIFLAVONOIDS; BLOOD GLUCOSE; CATARACT; CATECHIN; CINNAMOMUM ZEYLANICUM; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; GLYCOSYLATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LENS, CRYSTALLINE; MALE; PLANT EXTRACTS; PROANTHOCYANIDINS; RATS; RATS, WISTAR;

EID: 84888431072     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1214     Document Type: Article

References (40)

1. Internal Diabetes Federation. (2011) Diabetes Atlas 5th edition. International Diabetes Federation, Brussels, Belgium.
2. Michael, J., and, Fowler, M. D., (2008) Microvascular and macrovascular complications of diabetes. Clin. Diabetes 26, 77-82.
3. Congdon, N. G., Friedman, D. S., and, Lietman T., (2003) Important causes of visual impairment in the world today. JAMA 290, 2057-2060.
4. Stanga, P. E., Boyd, S. R., and, Hamilton, A. M., (1999) Ocular manifestations of diabetes mellitus. Curr. Opin. Ophthalmol. 10, 483-489.
5. Singh, R., Barden, A., Mori, T., and, Beilin, L., (2001) Advanced glycation end-products: a review. Diabetologia 44, 129-146.
6. Baynes, J. W., and, Thorpe, S. R., (1999) Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 48, 1-9.
7. Ahmed, N., (2005) Advanced glycation endproducts-role in pathology of diabetic complications. Diabetes Res. Clin. Pract. 67, 3-21.
8. Brownlee, M., (1995) Advanced protein glycosylation in diabetes and aging. Annu. Rev. Med. 46, 223-234.
9. Nagaraj, R. H., and, Sady, C., (1996) The presence of a glucose-derived Maillard reaction product in the human lens. FEBS Lett. 382, 234-238.
10. Vlassara, H., (1996) Advanced glycation end-products and atherosclerosis. Ann. Med. 28, 419-426.
11. Sell, D. R., and, Monnier, V. M., (1989) Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process. J. Biol. Chem. 264, 21597-21602.
12. Sell, D. R., Nagaraj, R. H., Grandhee, S. K., Odetti, P., Lapolla, A., Fogarty, J., and, Monnier, V. M., (1991) Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia. Diabetes Metab. Rev. 7, 239-251.
13. Vlassara, H., (1996) Advanced glycosylation in nephropathy of diabetes and aging. Adv. Nephrol. Necker Hosp. 25, 303-315.
14. Lyons, T. J., Silvestri, G., Dunn, J. A., Dyer, D. G., and, Baynes, J. W., (1991) Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts. Diabetes 40, 1010-1015.
15. Luthra, M., and, Balasubramanian, D., (1993) Nonenzymatic glycation alters protein structure and stability. A study of two eye lens crystallins. J. Biol. Chem. 268, 18119-18127.
16. Kumar, M. S., Reddy, P. Y., Kumar, P. A., Surolia, I., and, Reddy, G. B., (2004) Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: physiological significance and caveats of in vitro aggregation assays. Biochem. J. 379, 273-282.
17. Kumar, P. A., Kumar, M. S., and, Reddy, G. B., (2007) Effect of glycation on alpha-crystallin structure and chaperone-like function. Biochem. J. 408, 251-258.
18. Stitt, A., Gardiner, T. A., Alderson, N. L., Canning, P., Frizzell, N., Duffy, N., Boyle, C., Januszewski, A. S., Chachich, M., Baynes, J. W., and, Thorpe, S. R., (2002) The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes 51, 2826-2832.
19. Wada, R., Nishizawa, Y., Yagihashi, N., Takeuchi, M., Ishikawa, Y., Yasumura, K., Nakano, M., and, Yagihashi, S., (2001) Effects of OPB-9195, anti-glycation agent, on experimental diabetic neuropathy. Eur. J. Clin. Invest. 31, 513-520.
20. Vasan, S., Zhang, X., Kapurniotu, A., Bernhagen, J., Teichberg, S., Basgen, J., Wagle, D., Shih, D., Terlecky, I., Bucala, R., Cerami, A., Egan, J., and, Ulrich, P., (1996) An agent cleaving glucose-derived protein crosslinks in vitro and in vivo. Nature 382, 275-278.
21. Edelstein, D., and, Brownlee, M., (1992) Mechanistic studies of advanced glycosylation end product inhibition by aminoguanidine. Diabetes 41, 26-29.
22. Saraswat, M., Reddy, P. Y., Muthenna, P., and, Reddy, G. B., (2009) Prevention of non-enzymic glycation of proteins by dietary agents: prospects for alleviating diabetic complications. Br. J. Nutr. 101, 1714-1721.
23. Muthenna, P., Akileshwari, C., Saraswat, M., and, Bhanuprakash Reddy, G., (2011) Inhibition of advanced glycation end-product formation on eye lens protein by rutin. Br. J. Nutr. 25, 1-9.
24. Muthenna, P., Akileshwari, C., and, Reddy, G. B., (2012) Ellagic acid, a new antiglycating agent: its inhibition of N-(carboxymethyl)lysine. Biochem. J. 442, 221-230.
25. Kumar, P. A., Suryanarayana, P., Reddy, P. Y., and, Reddy, G. B., (2005) Modulation of alpha-crystallin chaperone activity in diabetic rat lens by curcumin. Mol. Vis. 11, 561-568.
26. Mrudula, T., Suryanarayana, P., Srinivas, P., and, Reddy, G. B., (2007) Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Biochem. Biophys. Res. Commun. 361, 528-532.
27. Saraswat, M., Suryanarayana, P., Reddy, P. Y., Patil, M. A., Balakrishna, N., and, Reddy, G. B., (2010) Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats. Mol. Vis. 16, 1525-1537.
28. Kumar, P. A., Reddy, P. Y., Srinivas, P. N., and, Reddy, G. B., (2009) Delay of diabetic cataract in rats by the antiglycating potential of cumin through modulation of alpha-crystallin chaperone activity. J. Nutr. Biochem. 20, 553-562.
29. Peng, X., Cheng, K. W., Ma, J., Chen, B., Ho, C. T., Lo, C., Chen, F., and, Wang, M., (2008) Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. J. Agric. Food Chem. 56, 1907-1911.
30. Peng, X., Ma, J., Chao, J., Sun, Z., Chang, R. C., Tse, I., Li, E. T., Chen, F., and, Wang, M., (2010) Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption. J. Agric. Food Chem. 58, 6692-6696.
31. Rahbar, S., and, Nadler, J. L., (1999) A new rapid method to detect inhibition of Amadori product generated by delta-gluconolactone. Clin. Chim. Acta. 287, 123-130.
32. Suryanarayana, P., Saraswat, M., Mrudula, T., Krishna, T. P., Krishnaswamy, K., and, Reddy, G. B., (2005) Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats. Invest. Ophthalmol. Vis. Sci. 46, 2092-2099.
33. Surolia, I., Sinha, S., Sarkar, D. P., Reddy, P. Y., Reddy, G. B., and, Surolia, A., (2008) Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin. PloS one. 3, e2927.
34. Nagaraj, R. H., Shipanova, I. N., and, Faust, F. M., (1996) Protein cross-linking by the Maillard reaction. Isolation, characterization, and in vivo detection of a lysine-lysine cross-link derived from methylglyoxal. J. Biol. Chem. 271, 19338-19345.
35. Ahmed, M. U., Brinkmann Frye, E., Degenhardt, T. P., Thorpe, S. R., and, Baynes, J. W., (1997) N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins. Biochem. J. 324 (Pt 2), 565-570.
36. Glomb, M. A., and, Monnier, V. M., (1995) Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction. J. Biol. Chem. 270, 10017-10026.
37. Brownlee, M., (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820.
38. Mohan, V., Sandeep, S., Deepa, R., Shah, B., and, Varghese, C., (2007) Epidemiology of type 2 diabetes: Indian scenario. Indian J. Med. Res. 125, 217-230.
39. King, H., Aubert, R. E., and, Herman, W. H., (1998) Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care. 21, 1414-1431.
40. Bengmark, S., (2007) Advanced glycation and lipoxidation end products-amplifiers of inflammation: the role of food. JPEN J. Parenter Enteral Nutr. 31, 430-440.