Concurrence of danish dementia and cataract: Insights from the interactions of dementia associated peptides with eye lens α-crystallin

PLoS ONE

Volumn 3, Issue 8, 2008, Pages

  Surolia, Ira ^a   Sinha, Sharmistha ^b   Sarkar, Debi Prasad ^a   Reddy, P Yadagiri ^c   Reddy, G Bhanuprakash ^c   Surolia, Avadhesha ^b,d  

^a UNIVERSITY OF DELHI   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c NATIONAL INSTITUTE OF NUTRITION   (India)

^d NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; CHAPERONE; HEAT SHOCK PROTEIN 70; PEPTIDE; AMYLOID BETA PROTEIN; ITM2B PROTEIN, HUMAN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ATAXIA; AUTOSOMAL DOMINANT DISORDER; CATARACT; COMORBIDITY; CONTROLLED STUDY; DEMENTIA; EX VIVO STUDY; FAMILIAL DANISH DEMENTIA; HEARING IMPAIRMENT; IN VITRO STUDY; LENS; NONHUMAN; ORGAN CULTURE; PROTEIN PROTEIN INTERACTION; VISUAL IMPAIRMENT; AGING; ANIMAL; DEGENERATIVE DISEASE; DISEASE MODEL; HUMAN; PATHOLOGY; PHYSIOLOGY; RAT; VISUAL DISORDER;

RATTUS;

AGING; ALPHA-CRYSTALLINS; AMYLOID BETA-PROTEIN; ANIMALS; ATAXIA; CATARACT; DEMENTIA; DISEASE MODELS, ANIMAL; HUMANS; LENS, CRYSTALLINE; MEMBRANE PROTEINS; MOLECULAR CHAPERONES; NEURODEGENERATIVE DISEASES; RATS; VISION DISORDERS;

EID: 51449085777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002927     Document Type: Article

References (33)

1. Dobson CM (1999) Protein misfolding, evolution and disease. Trends Biochem Sci 24: 329-332.
2. Carrell RW, Lomas DA (1997) Conformational disease. Lancet 350: 134-138.
3. Barral JM, Broadley SA, Schaffar G, Hartl FU (2004) Roles of molecular chaperones in protein misfolding diseases. Semin Cell Dev Biol 15: 17-29.
4. Vidal R, Revesz T, Rostagno A, Kim E, Holton JL, et al. (2000) A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred. Proc Natl Acad Sci U S A 97: 4920-4925.
5. Gibson G, Gunasekera N, Lee M, Lelyveld V, El-Agnaf OM, et al. (2004) Oligomerization and neurotoxicity of the amyloid ADan peptide implicated in familial Danish dementia. J Neurochem 88: 281-290.
6. Surolia I, Reddy GB, Sinha S (2006) Hierarchy and the mechanism of fibril formation in ADan peptides. J Neurochem 99: 537-548.
7. Surolia I, Sarkar DP, Sinha S (2008) Form and dimensions of aggregates dictate cytotoxicities of Danish dementia peptides. Biochem Biophys Res Commun, (In press).
8. Bek T (2000) Ocular changes in heredo-oto-ophthalmo-encephalopathy. Br J Ophthalmol 84: 1298-1302.
9. Stromgren E, Dalby A, Dalby MA, Ranheim B (1970) Cataract, deafness, cerebellar ataxia, psychosis and dementia - a new syndrome. Acta Neurol Scand 46: Suppl 43: 261+.
10. Rostagno A, Tomidokoro Y, Lashley T, Ng D, Plant G, et al. (2005) Chromosome 13 dementias. Cell Mol Life Sci 62: 1814-1825.
11. Goldstein LE, Muffat JA, Cherny RA, Moir RD, Ericsson MH, et al. (2003) Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease. Lancet 361: 1258-1265.
12. Harding JJ (1991) Post-translational modification of lens proteins in cataract. Lens Eye Toxic Res 8: 245-250.
13. Swamy MS, Abraham EC (1987) Lens protein composition, glycation and high molecular weight aggregation in aging rats. Invest Ophthalmol Vis Sci 28: 1693-1701.
14. Bloemendal H, de Jong W, Jaenicke R, Lubsen NH, Slingsby C, et al. (2004) Ageing and vision: structure, stability and function of lens crystallins. Prog Biophys Mol Biol 86: 407-485.
15. Buchner J (1996) Supervising the fold: functional principles of molecular chaperones. Faseb J 10: 10-19.
16. de Jong WW, Caspers GJ, Leunissen JA (1998) Genealogy of the alpha-crystallin-small heat-shock protein superfamily. Int J Biol Macromol 22: 151-162.
17. Raman B, Rao CM (1997) Chaperone-like activity and temperature-induced structural changes of alpha-crystallin. J Biol Chem 272: 23559-23564.
18. Klemenz R, Frohli E, Aoyama A, Hoffmann S, Simpson RJ, et al. (1991) Alpha B crystallin accumulation is a specific response to Ha-ras and v-mos oncogene expression in mouse NIH 3T3 fibroblasts. Mol Cell Biol 11: 803-812.
19. Kumar PA, Haseeb A, Suryanarayana P, Ehtesham NZ, Reddy GB (2005) Elevated expression of alphaA- and alphaB-crystallins in streptozotocin-induced diabetic rat. Arch Biochem Biophys 444: 77-83.
20. Horwitz J (2003) Alpha-crystallin. Exp Eye Res 76: 145-153.
21. Bera S, Thampi P, Cho WJ, Abraham EC (2002) A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity. Biochemistry 41: 12421-12426.
22. Rao G, Santhoshkumar P, Sharma KK (2008) Anti-chaperone betaA3/ A1(102-117) peptide interacting sites in human alphaB-crystallin. Mol Vis 14: 666-674.
23. Brady JP, Garland D, Duglas-Tabor Y, Robison WG Jr, Groome A, et al. (1997) Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin. Proc Natl Acad Sci U S A 94: 884-889.
24. Brady JP, Garland DL, Green DE, Tamm ER, Giblin FJ, et al. (2001) AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach. Invest Ophthalmol Vis Sci 42: 2924-2934.
25. Reddy GB, Das KP, Petrash JM, Surewicz WK (2000) Temperature-dependent chaperone activity and structural properties of human alphaA- and alphaB-crystallins. J Biol Chem 275: 4565-4570.
26. Srinivasan R, Jones EM, Liu K, Ghiso J, Marchant RE, et al. (2003) pH-dependent amyloid and protofibril formation by the ABri peptide of familial British dementia. J Mol Biol 333: 1003-1023.
27. Ramya TN, Surolia N, Surolia A (2006) 15-Deoxyspergualin modulates Plasmodium falciparum heat shock protein function. Biochem Biophys Res Commun 348: 585-592.
28. Frederikse PH, Ren XO (2002) Lens defects and age-related fiber cell degeneration in a mouse model of increased AbetaPP gene dosage in Down syndrome. Am J Pathol 161: 1985-1990.
29. Liang JJ (2000) Interaction between beta-amyloid and lens alphaB-crystallin. FEBS Lett 484: 98-101.
30. Stege GJ, Renkawek K, Overkamp PS, Verschuure P, van Rijk AF, et al. (1999) The molecular chaperone alphaB-crystallin enhances amyloid beta neurotoxicity. Biochem Biophys Res Commun 262: 152-156.
31. Stine WB Jr, Dahlgren KN, Krafft GA, LaDu MJ (2003) In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis. J Biol Chem 278: 11612-11622.
32. Kumar MS, Reddy PY, Kumar PA, Surolia I, Reddy GB (2004) Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: physiological significance and caveats of in vitro aggregation assays. Biochem J 379: 273-282.
33. Suryanarayana P, Kumar PA, Saraswat M, Petrash JM, Reddy GB (2004) Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract. Mol Vis 10: 148-154.