LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn's disease

Journal of Biomedical Science

Volumn 20, Issue 1, 2013, Pages

  Qiao, Yu Qi ^a,b   Huang, Mei Lan ^a,b   Xu, An Tao ^a,b   Zhao, Di ^a,b   Ran, Zhi Hua ^a,b   Shen, Jun ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DQ786243 PROTEIN; LONG UNTRANSLATED RNA; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; CREB1 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GENETIC TRANSFECTION; HUMAN; LEUKEMIA CELL LINE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSIENT TRANSFECTION; WESTERN BLOTTING; CHINA; GENE EXPRESSION REGULATION; GENETICS; JURKAT CELL LINE; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; YOUNG ADULT;

ADULT; BLOTTING, WESTERN; CHINA; CROHN DISEASE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; JURKAT CELLS; MALE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; T-LYMPHOCYTES, REGULATORY; YOUNG ADULT;

EID: 84888347061     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-20-87     Document Type: Article

References (37)

1. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Hwang HW, Mendell JT, British J Cancer 2006 94 776 780 10.1038/sj.bjc.6603023
2. lincRNAs act in the circuitry controlling pluripotency and differentiation. Guttman M, Donaghey J, Carey BW, Garber M, Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, et al. Nature 2011 477 295 300 10.1038/nature10398 21874018
3. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, et al. Nat Genet 2011 43 621 629 10.1038/ng.848 21642992
4. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, Thomas K, Presser A, Bernstein BE, van Oudenaarden A, et al. Proc Natl Acad Sci U S A 2009 106 11667 11672 10.1073/pnas.0904715106 19571010
5. Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Loewer S, Cabili MN, Guttman M, Loh YH, Thomas K, Park IH, Garber M, Curran M, Onder T, Agarwal S, et al. Nat Genet 2010 42 1113 1117 10.1038/ng.710 21057500
6. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, et al. Nature 2011 472 120 124 10.1038/nature09819 21423168
7. Long non-coding RNAs: insights into functions. Mercer TR, Dinger ME, Mattick JS, Nat Rev Genet 2009 10 155 159 10.1038/nrg2521 19188922
8. Molecular mechanisms of long noncoding RNAs. Wang KC, Chang HY, Mol Cell 2011 43 904 914 10.1016/j.molcel.2011.08.018 21925379
9. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cesana M, Cacchiarelli D, Legnini I, Santini T, Sthandier O, Chinappi M, Tramontano A, Bozzoni I, Cell 2011 147 358 369 10.1016/j.cell.2011.09.028 22000014
10. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Faghihi MA, Modarresi F, Khalil AM, Wood DE, Sahagan BG, Morgan TE, Finch CE, StLaurent G 3rd, Kenny PJ, Wahlestedt C, Nat Med 2008 14 723 730 10.1038/nm1784 18587408
11. Long non-coding RNAs in nervous system function and disease. Qureshi IA, Mattick JS, Mehler MF, Brain Res 2010 1338 20 35 20380817
12. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, et al. Nature 2010 464 1071 1076 10.1038/nature08975 20393566
13. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, Cui H, Nature 2008 451 202 206 10.1038/nature06468 18185590
14. Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Yang F, Zhang L, Huo XS, Yuan JH, Xu D, Yuan SX, Zhu N, Zhou WP, Yang GS, Wang YZ, et al. Hepatology 2011 54 1679 1689 10.1002/hep.24563 21769904
15. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. Kim HP, Leonard WJ, J Exp Med 2007 204 1543 1551 17591856 (Pubitemid 47048022)
16. The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road. Zhang L, Zhao Y, J Cell Physiol 2007 211 590 597 10.1002/jcp.21001 17311282 (Pubitemid 46683027)
17. Inflammatory bowel disease: cause and immunobiology. Baumgart DC, Carding SR, Lancet 2007 369 1627 1640 10.1016/S0140-6736(07)60750-8 17499605 (Pubitemid 46722636)
18. Regulatory T cells and immune tolerance. Sakaguchi S, Yamaguchi T, Nomura T, Ono M, Cell 2008 133 775 787 10.1016/j.cell.2008.05.009 18510923 (Pubitemid 351707693)
19. Foxp3 programs the development and function of CD4 + CD25+ regulatory T cells. Fontenot JD, Gavin MA, Rudensky AY, Nat immunol 2003 4 330 336 12612578 (Pubitemid 36432314)
20. Control of regulatory T cell development by the transcription factor Foxp3. Hori S, Nomura T, Sakaguchi S, Science 2003 299 1057 1061 10.1126/science.1079490 12522256 (Pubitemid 36222930)
21. FOXP3 acts as a rheostat of the immune response. Ochs HD, Ziegler SF, Torgerson TR, Immunol Rev 2005 203 156 164 10.1111/j.0105-2896.2005.00231.x 15661028 (Pubitemid 40179700)
22. Regulatory T cells in inflammatory bowel disease. Boden EK, Snapper SB, Curr Opin Gastroenterol 2008 24 733 741 10.1097/MOG.0b013e328311f26e 19125486
23. A simple index of Crohn's-disease activity. Harvey RF, Bradshaw JM, Lancet 1980 1 514 6102236
24. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Satsangi J, Silverberg MS, Vermeire S, Colombel JF, Gut 2006 55 749 753 10.1136/gut.2005.082909 16698746 (Pubitemid 43764536)
25. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Livak KJ, Schmittgen TD, Methods 2001 25 402 408 10.1006/meth.2001.1262 11846609 (Pubitemid 34164012)
26. Expression of CD4+ forkhead box P3 (FOXP3) + regulatory T cells in inflammatory bowel disease. Wang Y, Liu XP, Zhao ZB, Chen JH, Yu CG, J Dig Dis 2011 12 286 294 10.1111/j.1751-2980.2011.00505.x 21791023
27. Characterization of FOXP3 + CD4+ regulatory T cells in Crohn's disease. Saruta M, Yu QT, Fleshner PR, Mantel PY, Schmidt-Weber CB, Banham AH, Papadakis KA, Clin Immunol 2007 125 281 290 10.1016/j.clim.2007.08.003 17897887 (Pubitemid 350123608)
28. The anti-inflammatory target A(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn's disease. Ochaion A, Bar-Yehuda S, Cohen S, Barer F, Patoka R, Amital H, Reitblat T, Reitblat A, Ophir J, Konfino I, et al. Cell Immunol 2009 258 115 122 10.1016/j.cellimm.2009.03.020 19426966
29. What turns on Foxp3? von Boehmer H, Nolting J, Nat Immunol 2008 9 121 122 10.1038/ni0208-121 18204423
30. The role of the transcription factor CREB in immune function. Wen AY, Sakamoto KM, Miller LS, J Immunol 2010 185 6413 6419 10.4049/jimmunol.1001829 21084670
31. FOXP3+ regulatory T cells in the human immune system. Sakaguchi S, Miyara M, Costantino CM, Hafler DA, Nat Rev Immunol 2010 10 490 500 10.1038/nri2785 20559327
32. DNA methylation controls Foxp3 gene expression. Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J, Eur J Immunol 2008 38 1654 1663 10.1002/eji.200838105 18493985
33. Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells. Polansky JK, Schreiber L, Thelemann C, Ludwig L, Kruger M, Baumgrass R, Cording S, Floess S, Hamann A, Huehn J, J Mol Med (Berl) 2010 88 1029 1040 10.1007/s00109-010-0642-1 20574810
34. Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells. Yang C, Li X, Wang Y, Zhao L, Chen W, Gene 2012 496 8 16 10.1016/j.gene.2012.01.012 22285928
35. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Wang J, Liu X, Wu H, Ni P, Gu Z, Qiao Y, Chen N, Sun F, Fan Q, Nucleic Acids Res 2010 38 5366 5383 10.1093/nar/gkq285 20423907
36. Cutting edge: influence of Tmevpg1, a long intergenic noncoding RNA, on the expression of Ifng by Th1 cells. Collier SP, Collins PL, Williams CL, Boothby MR, Aune TM, J Immunol 2012 189 2084 2088 10.4049/jimmunol.1200774 22851706
37. Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs. Wang Z, Hong J, Sun W, Xu G, Li N, Chen X, Liu A, Xu L, Sun B, Zhang JZ, J Clin Invest 2006 116 2434 2441 16906223. (Pubitemid 44330142)