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Volumn 91, Issue 10, 2013, Pages 625-633

C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2

Author keywords

BRET; C5a; inflammation; interleukin 10; macrophages

Indexed keywords

COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A [DEARGININE]; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5L2 RECEPTOR; COMPLEMENT RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84888315392     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.48     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 39749127834 scopus 로고    scopus 로고
    • Receptors for complement C5a the importance of C5aR and the enigmatic role of C5L2
    • Lee H, Whitfeld PL, Mackay CR. Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2. Immunol Cell Biol 2008; 86: 153-160.
    • (2008) Immunol Cell Biol , vol.86 , pp. 153-160
    • Lee, H.1    Whitfeld, P.L.2    Mackay, C.R.3
  • 2
    • 35348821843 scopus 로고    scopus 로고
    • Function, structure and therapeutic potential of complement C5a receptors
    • Monk PN, Scola AM, Madala P, Fairlie DP. Function, structure and therapeutic potential of complement C5a receptors. Br J Pharmacol 2007; 152: 429-448.
    • (2007) Br J Pharmacol , vol.152 , pp. 429-448
    • Monk, P.N.1    Scola, A.M.2    Madala, P.3    Fairlie, D.P.4
  • 3
    • 1142310879 scopus 로고    scopus 로고
    • The dark side of C5a in sepsis
    • Ward PA. The dark side of C5a in sepsis. Nat Rev Immunol 2004; 4: 133-142.
    • (2004) Nat Rev Immunol , vol.4 , pp. 133-142
    • Ward, P.A.1
  • 4
    • 0021952732 scopus 로고
    • Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des arg
    • Marder SR, Chenoweth DE, Goldstein IM, Perez HD. Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des arg. J Immunol 1985; 134: 3325-3331.
    • (1985) J Immunol , vol.134 , pp. 3325-3331
    • Marder, S.R.1    Chenoweth, D.E.2    Goldstein, I.M.3    Perez, H.D.4
  • 5
    • 36048937343 scopus 로고    scopus 로고
    • Complement-targeted therapeutics
    • Ricklin D, Lambris JD. Complement-targeted therapeutics. Nat Biotechnol 2007; 25: 1265-1275.
    • (2007) Nat Biotechnol , vol.25 , pp. 1265-1275
    • Ricklin, D.1    Lambris, J.D.2
  • 6
    • 0346786461 scopus 로고    scopus 로고
    • A key role of C5a/C5aR activation for the development of sepsis
    • Riedemann NC, Guo R-F, Ward PA. A key role of C5a/C5aR activation for the development of sepsis. J Leukoc Biol 2003; 74: 966-970.
    • (2003) J Leukoc Biol , vol.74 , pp. 966-970
    • Riedemann, N.C.1    Guo, R.-F.2    Ward, P.A.3
  • 8
    • 3042544047 scopus 로고    scopus 로고
    • Pathogenesis of rheumatoid arthritis
    • Weissmann G. Pathogenesis of rheumatoid arthritis. J Clin Rheumatol 2004; 10: S26-S31.
    • (2004) J Clin Rheumatol , vol.10
    • Weissmann, G.1
  • 9
    • 0025890276 scopus 로고
    • Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells
    • Boulay F, Mery L, Tardif M, Brouchon L, Vignais P. Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells. Biochemistry 1991; 30: 2993-2999.
    • (1991) Biochemistry , vol.30 , pp. 2993-2999
    • Boulay, F.1    Mery, L.2    Tardif, M.3    Brouchon, L.4    Vignais, P.5
  • 10
    • 0026078539 scopus 로고
    • The chemotactic receptor for human C5a anaphylatoxin
    • Gerard NP, Gerard C. The chemotactic receptor for human C5a anaphylatoxin. Nature 1991; 349: 614-617.
    • (1991) Nature , vol.349 , pp. 614-617
    • Gerard, N.P.1    Gerard, C.2
  • 11
    • 0033709969 scopus 로고    scopus 로고
    • A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells
    • Ohno M, Hirata T, Enomoto M, Araki T, Ishimaru H, Takahashi TA. A putative chemoattractant receptor, C5L2, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells. Mol Immunol 2000; 37: 407-412.
    • (2000) Mol Immunol , vol.37 , pp. 407-412
    • Ohno, M.1    Hirata, T.2    Enomoto, M.3    Araki, T.4    Ishimaru, H.5    Takahashi, T.A.6
  • 12
    • 0028564917 scopus 로고
    • Mapping of the C5a receptor signal transduction network in human neutrophils
    • Buhl AM, Avdi N, Worthen GS, Johnson GL. Mapping of the C5a receptor signal transduction network in human neutrophils. Proc Natl Acad Sci USA 1994; 91: 9190-9194.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9190-9194
    • Buhl, A.M.1    Avdi, N.2    Worthen, G.S.3    Johnson, G.L.4
  • 13
    • 0037423283 scopus 로고    scopus 로고
    • Phosphorylation of Key Serine Residues Is Required for Internalization of the Complement 5a (C5a) Anaphylatoxin Receptor via a beta-Arrestin, Dynamin, and Clathrin-dependent Pathway
    • Braun L, Christophe T, Boulay F. Phosphorylation of Key Serine Residues Is Required for Internalization of the Complement 5a (C5a) Anaphylatoxin Receptor via a beta-Arrestin, Dynamin, and Clathrin-dependent Pathway. J Biol Chem 2003; 278: 4277-4285.
    • (2003) J Biol Chem , vol.278 , pp. 4277-4285
    • Braun, L.1    Christophe, T.2    Boulay, F.3
  • 14
    • 0036510770 scopus 로고    scopus 로고
    • The orphan receptor c5l2 has high affinity binding sites for complement Fragments C5a and C5a des-Arg74
    • Cain SA, Monk PN. The Orphan Receptor C5L2 Has High Affinity Binding Sites for Complement Fragments C5a and C5a des-Arg74. J Biol Chem 2002; 277: 7165-7169.
    • (2002) J Biol Chem , vol.277 , pp. 7165-7169
    • Cain, S.A.1    Monk, P.N.2
  • 16
    • 33846027130 scopus 로고    scopus 로고
    • Ligand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell lines
    • Johswich K, Martin M, Thalmann J, Rheinheimer C, Monk PN, Klos A. Ligand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell lines. J Biol Chem 2006; 281: 39088-39095.
    • (2006) J Biol Chem , vol.281 , pp. 39088-39095
    • Johswich, K.1    Martin, M.2    Thalmann, J.3    Rheinheimer, C.4    Monk, P.N.5    Klos, A.6
  • 17
    • 28844434626 scopus 로고    scopus 로고
    • An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2
    • Gerard NP, Lu B, Liu P, Craig S, Fujiwara Y, Okinaga S et al. An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2. J Biol Chem 2005; 280: 39677-39680.
    • (2005) J Biol Chem , vol.280 , pp. 39677-39680
    • Gerard, N.P.1    Lu, B.2    Liu, P.3    Craig, S.4    Fujiwara, Y.5    Okinaga, S.6
  • 18
    • 60949109793 scopus 로고    scopus 로고
    • The human complement fragment receptor, C5L2, is a recycling decoy receptor
    • Scola A-M, Johswich K-O, Morgan BP, Klos A, Monk PN. The human complement fragment receptor, C5L2, is a recycling decoy receptor. Mol Immunol 2009; 46: 1149-1162.
    • (2009) Mol Immunol , vol.46 , pp. 1149-1162
    • Scola, A.-M.1    Johswich, K.-O.2    Morgan, B.P.3    Klos, A.4    Monk, P.N.5
  • 19
    • 77951250395 scopus 로고    scopus 로고
    • The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction
    • Bamberg CE, Mackay CR, Lee H, Zahra D, Jackson J, Lim YS et al. The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. J Biol Chem2009; 285: 7633-7644.
    • (2009) J Biol Chem , vol.285 , pp. 7633-7644
    • Bamberg, C.E.1    Mackay, C.R.2    Lee, H.3    Zahra, D.4    Jackson, J.5    Lim, Y.S.6
  • 20
    • 79954516650 scopus 로고    scopus 로고
    • G protein-coupled receptors: Walking handin- hand talking hand-in-hand
    • Vischer HF, Watts AO, Nijmeijer S, Leurs R. G protein-coupled receptors: walking handin- hand, talking hand-in-hand? Br J Pharmacol 2011; 163: 246-260.
    • (2011) Br J Pharmacol , vol.163 , pp. 246-260
    • Vischer, H.F.1    Watts, A.O.2    Nijmeijer, S.3    Leurs, R.4
  • 21
    • 77955874300 scopus 로고    scopus 로고
    • Time-resolved FRET between GPCR ligands reveals oligomers in native tissues
    • Albizu L, Cottet M, Kralikova M, Stoev S, Seyer R, Brabet I et al. Time-resolved FRET between GPCR ligands reveals oligomers in native tissues. Nat Chem Biol 2010; 6: 587-594.
    • (2010) Nat Chem Biol , vol.6 , pp. 587-594
    • Albizu, L.1    Cottet, M.2    Kralikova, M.3    Stoev, S.4    Seyer, R.5    Brabet, I.6
  • 24
    • 13444269196 scopus 로고    scopus 로고
    • Monitoring the formation of dynamic G-protein-coupled receptor-protein complexes in living cells
    • Pfleger KDG, Eidne KA. Monitoring the formation of dynamic G-protein-coupled receptor-protein complexes in living cells. Biochem J 2005; 385: 625-637.
    • (2005) Biochem J , vol.385 , pp. 625-637
    • Kdg, P.1    Eidne, K.A.2
  • 25
    • 0041315583 scopus 로고    scopus 로고
    • C5a Receptor Oligomerization: II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast
    • Floyd DH, Geva A, Bruinsma SP, Overton MC, Blumer KJ, Baranski TJ. C5a Receptor Oligomerization: II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast. J Biol Chem 2003; 278: 35354-35361.
    • (2003) J Biol Chem , vol.278 , pp. 35354-35361
    • Floyd, D.H.1    Geva, A.2    Bruinsma, S.P.3    Overton, M.C.4    Blumer, K.J.5    Baranski, T.J.6
  • 26
    • 27844541754 scopus 로고    scopus 로고
    • Protein-coupled receptor kinases promote phosphorylation and beta-Arrestin-mediated internalization of CCR5 Homoand Hetero-oligomers
    • Huttenrauch F, Pollok-Kopp B, Oppermann MG. Protein-coupled receptor kinases promote phosphorylation and beta-Arrestin-mediated internalization of CCR5 Homoand Hetero-oligomers. J Biol Chem 2005; 280: 37503-37515.
    • (2005) J Biol Chem , vol.280 , pp. 37503-37515
    • Huttenrauch, F.1    Pollok-Kopp, B.2    Oppermann, M.G.3
  • 27
    • 84876275433 scopus 로고    scopus 로고
    • A Comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly G coupled GPCR (C5aR) signalling
    • Halai R, Croker DE, Suen JY, Fairlie DP, Cooper MA. A Comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly G coupled GPCR (C5aR) signalling. Biosensors 2012; 2: 273-290.
    • (2012) Biosensors , vol.2 , pp. 273-290
    • Halai, R.1    Croker, D.E.2    Suen, J.Y.3    Fairlie, D.P.4    Cooper, M.A.5
  • 28
    • 84868545657 scopus 로고    scopus 로고
    • C5a receptor-dependent cell activation by physiological concentrations of desarginated c5a: Insights from a novel label-free cellular assay
    • Reis ES, Chen H, Sfyroera G, Monk PN, Kohl J, Ricklin D et al. C5a receptor-dependent cell activation by physiological concentrations of desarginated c5a: insights from a novel label-free cellular assay. J Immunol 2012; 189: 4797-4805.
    • (2012) J Immunol , vol.189 , pp. 4797-4805
    • Reis, E.S.1    Chen, H.2    Sfyroera, G.3    Monk, P.N.4    Kohl, J.5    Ricklin, D.6
  • 29
    • 0033519733 scopus 로고    scopus 로고
    • Lowmolecular- weight peptidic and cyclic antagonists of the receptor for the complement factor C5a
    • Finch AM, Wong AK, Paczkowski NJ, Wadi SK, Craik DJ, Fairlie DP et al. Lowmolecular- weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. J Med Chem 1999; 42: 1965-1974.
    • (1999) J Med Chem , vol.42 , pp. 1965-1974
    • Finch, A.M.1    Wong, A.K.2    Paczkowski, N.J.3    Wadi, S.K.4    Craik, D.J.5    Fairlie, D.P.6
  • 31
    • 78650668602 scopus 로고    scopus 로고
    • A critical role for C5L2 in the Pathogenesis of experimental allergic asthma
    • Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P et al. A critical role for C5L2 in the Pathogenesis of experimental allergic asthma. J Immunol 2010; 185: 6741-6752.
    • (2010) J Immunol , vol.185 , pp. 6741-6752
    • Zhang, X.1    Schmudde, I.2    Laumonnier, Y.3    Pandey, M.K.4    Clark, J.R.5    Konig, P.6
  • 33
    • 84873472582 scopus 로고    scopus 로고
    • C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
    • Lim J, Iyer A, Suen JY, Seow V, Reid RC, Brown L et al. C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling. FASEB J 2013; 27: 822-831.
    • (2013) FASEB J , vol.27 , pp. 822-831
    • Lim, J.1    Iyer, A.2    Suen, J.Y.3    Seow, V.4    Reid, R.C.5    Brown, L.6
  • 34
    • 84874281187 scopus 로고    scopus 로고
    • New insights for C5a and C5a receptors in sepsis
    • Yan C, Gao H. New insights for C5a and C5a receptors in sepsis. Front Immunol 2012; 3: 368.
    • (2012) Front Immunol , vol.3 , pp. 368
    • Yan, C.1    Gao, H.2
  • 35
    • 84880028085 scopus 로고    scopus 로고
    • The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation
    • Bosmann M, Haggadone MD, Zetoune FS, Sarma JV, Ward PA. The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation. Eur J Immunol 2013; 43: 1907-1913.
    • (2013) Eur J Immunol , vol.43 , pp. 1907-1913
    • Bosmann, M.1    Haggadone, M.D.2    Zetoune, F.S.3    Sarma, J.V.4    Ward, P.A.5
  • 36
    • 33947110020 scopus 로고    scopus 로고
    • C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
    • Chen N-J, Mirtsos C, Suh D, Lu Y-C, Lin W-J, McKerlie C et al. C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature 2007; 446: 203-207.
    • (2007) Nature , vol.446 , pp. 203-207
    • Chen, N.-J.1    Mirtsos, C.2    Suh, D.3    Lu, Y.-C.4    Lin, W.-J.5    McKerlie, C.6
  • 39
    • 12144288237 scopus 로고    scopus 로고
    • Human IL-23-producing type 1 macrophages promote but IL-10- producing type 2 macrophages subvert immunity to (myco)bacteria
    • Verreck FAW. Human IL-23-producing type 1 macrophages promote but IL-10- producing type 2 macrophages subvert immunity to (myco)bacteria. Proc Natl Acad Sci USA 2004; 101: 4560-4565.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4560-4565
    • Faw, V.1
  • 40
    • 33747312516 scopus 로고    scopus 로고
    • Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged proteinprotein interactions in live cells
    • Pfleger KD, Dromey JR, Dalrymple MB, Lim EM, Thomas WG, Eidne KA. Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged proteinprotein interactions in live cells. Cell Signal 2006; 18: 1664-1670.
    • (2006) Cell Signal , vol.18 , pp. 1664-1670
    • Pfleger, K.D.1    Dromey, J.R.2    Dalrymple, M.B.3    Lim, E.M.4    Thomas, W.G.5    Eidne, K.A.6
  • 42
    • 20144384755 scopus 로고    scopus 로고
    • An automated method to quantify and visualize colocalized fluorescent signals
    • Jaskolski F, Mulle C, Manzoni OJ. An automated method to quantify and visualize colocalized fluorescent signals. J Neurosci Methods 2005; 146: 42-49.
    • (2005) J Neurosci Methods , vol.146 , pp. 42-49
    • Jaskolski, F.1    Mulle, C.2    Manzoni, O.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.