A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties

Journal of Biological Chemistry

Volumn 288, Issue 47, 2013, Pages 34055-34072

  Luo, Min ^a,d   Lu, Xinping ^a   Zhu, Rong ^a,e   Zhang, Zhenhuan ^a,f   Chow, Carson C ^b   Li, Rong ^c   Stoney Jr , Simons ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e FUDAN UNIVERSITY   (China)

^f UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGONIST ACTIVITY; BIOLOGICAL RESPONSE; COMPETITION ASSAYS; CONSERVED PROTEINS; ELONGATION FACTOR; GLUCOCORTICOID RECEPTOR; LIGAND BINDING DOMAIN; TRANSCRIPTION INITIATION;

ASSAYS; GENES; HORMONES; PROTEINS;

TRANSCRIPTION;

GLUCOCORTICOID RECEPTOR; NELF A PROTEIN; NELF B PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN SUBUNIT; REPORTER GENE; TRANSCRIPTION REGULATION;

COFACTOR ACTION; COMPETITIVE DECELERATOR; EC50; GENE INDUCTION; GENE TRANSCRIPTION; GLUCOCORTICOID RECEPTOR; MATHEMATICAL MODELING; NELF-A AND NELF-B; STEROID HORMONE; TRANSCRIPTION FACTORS;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, GLUCOCORTICOID; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ELONGATION FACTORS;

EID: 84888314261     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.512426     Document Type: Article

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