메뉴 건너뛰기




Volumn 287, Issue 49, 2012, Pages 40982-40995

Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation

Author keywords

[No Author keywords available]

Indexed keywords

GENES;

EID: 84870363100     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.414805     Document Type: Article
Times cited : (14)

References (51)
  • 1
    • 0035813090 scopus 로고    scopus 로고
    • Coregulator codes of transcriptional regulation by nuclear receptors
    • Rosenfeld, M. G., and Glass, C. K. (2001) Coregulator codes of transcriptional regulation by nuclear receptors. J. Biol. Chem. 276, 36865-36868
    • (2001) J. Biol. Chem. , vol.276 , pp. 36865-36868
    • Rosenfeld, M.G.1    Glass, C.K.2
  • 2
    • 3242784885 scopus 로고    scopus 로고
    • Mechanism of the nuclear receptor molecular switch
    • DOI 10.1016/j.tibs.2004.04.006, PII S096800040400088X
    • Nagy, L., and Schwabe, J. W. (2004) Mechanism of the nuclear receptor molecular switch. Trends Biochem. Sci. 29, 317-324 (Pubitemid 38968764)
    • (2004) Trends in Biochemical Sciences , vol.29 , Issue.6 , pp. 317-324
    • Nagy, L.1    Schwabe, J.W.R.2
  • 3
    • 33645820442 scopus 로고    scopus 로고
    • Transcription in four dimensions. Nuclear receptor-directed initiation of gene expression
    • Métivier, R., Reid, G., and Gannon, F. (2006) Transcription in four dimensions. Nuclear receptor-directed initiation of gene expression.EMBORep. 7, 161-167
    • (2006) EMBORep. , vol.7 , pp. 161-167
    • Métivier, R.1    Reid, G.2    Gannon, F.3
  • 4
    • 33744792310 scopus 로고    scopus 로고
    • Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
    • DOI 10.1101/gad.1424806
    • Rosenfeld, M. G., Lunyak, V. V., and Glass, C. K. (2006) Sensors and signals. A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 20, 1405-1428 (Pubitemid 43830648)
    • (2006) Genes and Development , vol.20 , Issue.11 , pp. 1405-1428
    • Rosenfeld, M.G.1    Lunyak, V.V.2    Glass, C.K.3
  • 5
    • 82655174048 scopus 로고    scopus 로고
    • Steroid receptor coactivators 1, 2, and 3. Critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy
    • Johnson, A. B., and O'Malley, B. W. (2012) Steroid receptor coactivators 1, 2, and 3. Critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy. Mol. Cell. Endocrinol. 348, 430-439
    • (2012) Mol. Cell. Endocrinol. , vol.348 , pp. 430-439
    • Johnson, A.B.1    O'Malley, B.W.2
  • 8
    • 84855829727 scopus 로고    scopus 로고
    • Deducing the temporal order of cofactor function in ligand-regulated gene transcription. Theory and experimental verification
    • Dougherty, E. J., Guo, C., Simons, S. S., Jr., and Chow, C. C. (2012) Deducing the temporal order of cofactor function in ligand-regulated gene transcription. Theory and experimental verification. PLoS ONE 7, e30225
    • (2012) PLoS ONE , vol.7
    • Dougherty, E.J.1    Guo, C.2    Simons Jr., S.S.3    Chow, C.C.4
  • 13
    • 84856757508 scopus 로고    scopus 로고
    • Selective roles for cAMP response element-binding protein-binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells
    • Ianculescu, I., Wu, D. Y., Siegmund, K. D., and Stallcup, M. R. (2012) Selective roles for cAMP response element-binding protein-binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells. J. Biol. Chem. 287, 4000-4013
    • (2012) J. Biol. Chem. , vol.287 , pp. 4000-4013
    • Ianculescu, I.1    Wu, D.Y.2    Siegmund, K.D.3    Stallcup, M.R.4
  • 14
  • 16
    • 47549090254 scopus 로고    scopus 로고
    • NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
    • DOI 10.1101/gad.1643208
    • Gilchrist, D. A., Nechaev, S., Lee, C., Ghosh, S. K., Collins, J. B., Li, L., Gilmour, D. S., and Adelman, K. (2008) NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly. Genes Dev. 22, 1921-1933 (Pubitemid 352008640)
    • (2008) Genes and Development , vol.22 , Issue.14 , pp. 1921-1933
    • Gilchrist, D.A.1    Nechaev, S.2    Lee, C.3    Ghosh, S.K.B.4    Collins, J.B.5    Li, L.6    Gilmour, D.S.7    Adelman, K.8
  • 17
    • 41549134049 scopus 로고    scopus 로고
    • Poised polymerases. On your mark... get set... go!
    • Price, D. H. (2008) Poised polymerases. On your mark . . . get set . . . go! Mol. Cell 30, 7-10
    • (2008) Mol. Cell , vol.30 , pp. 7-10
    • Price, D.H.1
  • 18
    • 70249104647 scopus 로고    scopus 로고
    • Defining mechanisms that regulate RNA polymerase II transcription in vivo
    • Fuda, N. J., Ardehali, M. B., and Lis, J. T. (2009) Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 461, 186-192
    • (2009) Nature , vol.461 , pp. 186-192
    • Fuda, N.J.1    Ardehali, M.B.2    Lis, J.T.3
  • 20
    • 77249119220 scopus 로고    scopus 로고
    • Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions
    • Paakinaho, V., Makkonen, H., Jääskeläinen, T., and Palvimo, J. J. (2010) Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions. Mol. Endocrinol. 24, 511-525
    • (2010) Mol. Endocrinol. , vol.24 , pp. 511-525
    • Paakinaho, V.1    Makkonen, H.2    Jääskeläinen, T.3    Palvimo, J.J.4
  • 21
    • 57349162149 scopus 로고    scopus 로고
    • Histone modifications, but not nucleosomal positioning, correlate with major histocompatibility complex class I promoter activity in different tissues in vivo
    • Kotekar, A. S., Weissman, J. D., Gegonne, A., Cohen, H., and Singer, D. S. (2008) Histone modifications, but not nucleosomal positioning, correlate with major histocompatibility complex class I promoter activity in different tissues in vivo. Mol. Cell. Biol. 28, 7323-7336
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 7323-7336
    • Kotekar, A.S.1    Weissman, J.D.2    Gegonne, A.3    Cohen, H.4    Singer, D.S.5
  • 22
    • 0037723918 scopus 로고    scopus 로고
    • The importance of being varied in steroid receptor transactivation
    • Stoney Simons, S., Jr. (2003) The importance of being varied in steroid receptor transactivation. Trends Pharmacol. Sci. 24, 253-259
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 253-259
    • Stoney Simons Jr., S.1
  • 23
    • 82655162285 scopus 로고    scopus 로고
    • The road less traveled. New views of steroid receptor action from the path of dose-response curves
    • Simons, S. S., Jr., and Chow, C. C. (2012) The road less traveled. New views of steroid receptor action from the path of dose-response curves. Mol. Cell. Endocrinol. 348, 373-382
    • (2012) Mol. Cell. Endocrinol. , vol.348 , pp. 373-382
    • Simons Jr., S.S.1    Chow, C.C.2
  • 24
    • 2542486258 scopus 로고    scopus 로고
    • Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors
    • DOI 10.1210/me.2003-0421
    • Wang, Q., Blackford, J. A., Jr., Song, L. N., Huang, Y., and Cho, S., Simons, S. S., Jr. (2004) Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors. Mol. Endocrinol. 18, 1376-1395 (Pubitemid 38692177)
    • (2004) Molecular Endocrinology , vol.18 , Issue.6 , pp. 1376-1395
    • Wang, Q.1    Blackford Jr., J.A.2    Song, L.-N.3    Huang, Y.4    Cho, S.5    Simons Jr., S.S.6
  • 25
    • 0035842893 scopus 로고    scopus 로고
    • BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
    • DOI 10.1083/jcb.200108049
    • Ye, Q., Hu, Y. F., Zhong, H., Nye, A. C., Belmont, A. S., and Li, R. (2001) BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J. Cell Biol. 155, 911-921 (Pubitemid 34286243)
    • (2001) Journal of Cell Biology , vol.155 , Issue.6 , pp. 911-921
    • Ye, Q.1    Hu, Y.-F.2    Zhong, H.3    Nye, A.C.4    Belmont, A.S.5    Li, R.6
  • 26
    • 0029833193 scopus 로고    scopus 로고
    • Induction properties of a transiently transfected glucocorticoid- responsive gene vary with glucocorticoid receptor concentration
    • Szapary, D., Xu, M., and Simons, S. S., Jr. (1996) Induction properties of a transiently transfected glucocorticoid-responsive gene vary with glucocorticoid receptor concentration. J. Biol. Chem. 271, 30576-30582
    • (1996) J. Biol. Chem. , vol.271 , pp. 30576-30582
    • Szapary, D.1    Xu, M.2    Simons Jr., S.S.3
  • 27
    • 0037147260 scopus 로고    scopus 로고
    • Modulation of induction properties of glucocorticoid receptor-agonist and -antagonist complexes by coactivators involves binding to receptors but is independent of ability of coactivators to augment transactivation
    • DOI 10.1074/jbc.M205536200
    • He, Y., Szapary, D., and Simons, S. S., Jr. (2002) Modulation of induction properties of glucocorticoid receptor-agonist and -antagonist complexes by coactivators involves binding to receptors but is independent of ability of coactivators to augment transactivation. J. Biol. Chem. 277, 49256-49266 (Pubitemid 36014354)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49256-49266
    • He, Y.1    Szapary, D.2    Simons Jr., S.S.3
  • 28
    • 0037066790 scopus 로고    scopus 로고
    • Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors
    • DOI 10.1074/jbc.M112330200
    • Kaul, S., Blackford, J. A., Jr., Cho, S., and Simons, S. S., Jr. (2002) Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors. J. Biol. Chem. 277, 12541-12549 (Pubitemid 34952612)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.15 , pp. 12541-12549
    • Kaul, S.1    Blackford Jr., J.A.2    Cho, S.3    Stoney Jr., S.S.4
  • 30
    • 33846912187 scopus 로고    scopus 로고
    • STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression
    • DOI 10.1128/MCB.01360-06
    • He, Y., and Simons, S. S., Jr. (2007) STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression. Mol. Cell. Biol. 27, 1467-1485 (Pubitemid 46239827)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.4 , pp. 1467-1485
    • He, Y.1    Simons Jr., S.S.2
  • 31
    • 77950682598 scopus 로고    scopus 로고
    • STAMP alters the growth of transformed and ovarian cancer cells
    • He, Y., Blackford, J. A., Jr., Kohn, E. C., and Simons, S. S., Jr. (2010) STAMP alters the growth of transformed and ovarian cancer cells. BMC Cancer 10, 128
    • (2010) BMC Cancer , vol.10 , pp. 128
    • He, Y.1    Blackford Jr., J.A.2    Kohn, E.C.3    Simons Jr., S.S.4
  • 32
    • 0035816687 scopus 로고    scopus 로고
    • Transactivation specificity of glucocorticoid versus progesterone receptors. Role of functionally different interactions of transcription factors with amino- and carboxylterminal receptor domains
    • Song, L.N., Huse, B., Rusconi, S., and Simons, S. S., Jr. (2001) Transactivation specificity of glucocorticoid versus progesterone receptors. Role of functionally different interactions of transcription factors with amino- and carboxylterminal receptor domains. J. Biol. Chem. 276, 24806-24816
    • (2001) J. Biol. Chem. , vol.276 , pp. 24806-24816
    • Song, L.N.1    Huse, B.2    Rusconi, S.3    Simons Jr., S.S.4
  • 33
    • 0030912539 scopus 로고    scopus 로고
    • The transcriptional co-activator p/CIP binds CBP and mediates nuclear- receptor function
    • DOI 10.1038/42652
    • Torchia, J., Rose, D. W., Inostroza, J., Kamei, Y., Westin, S., Glass, C. K., and Rosenfeld, M. G. (1997) The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 387, 677-684 (Pubitemid 27270601)
    • (1997) Nature , vol.387 , Issue.6634 , pp. 677-684
    • Torchia, J.1    Rose, D.W.2    Inostroza, J.3    Kamei, Y.4    Westin, S.5    Glass, C.K.6    Rosenfeld, M.G.7
  • 34
    • 0032977071 scopus 로고    scopus 로고
    • Quantity of partial agonist activity for antiglucocorticoids complexed with mutant glucocorticoid receptors is constant in two different transactivation assays but not predictable from steroid structure
    • DOI 10.1016/S0960-0760(99)00021-7, PII S0960076099000217
    • Sarlis, N. J., Bayly, S. F., Szapary, D., and Simons, S. S., Jr. (1999) Quantity of partial agonist activity for antiglucocorticoids complexed with mutant glucocorticoid receptors is constant in two different transactivation assays but not predictable from steroid structure. J. Steroid Biochem. Molec. Biol. 68, 89-102 (Pubitemid 29242838)
    • (1999) Journal of Steroid Biochemistry and Molecular Biology , vol.68 , Issue.3-4 , pp. 89-102
    • Sarlis, N.J.1    Bayly, S.F.2    Szapary, D.3    Simons Jr., S.S.4
  • 36
    • 47649127453 scopus 로고    scopus 로고
    • Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression
    • DOI 10.1021/bi800472w
    • Tao, Y. G., Xu, Y., Xu, H. E., and Simons, S. S., Jr. (2008) Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression. Biochemistry 47, 7648-7662 (Pubitemid 352019496)
    • (2008) Biochemistry , vol.47 , Issue.29 , pp. 7648-7662
    • Tao, Y.-G.1    Xu, Y.2    Xu, H.E.3    Simons Jr., S.S.4
  • 37
    • 78751483455 scopus 로고    scopus 로고
    • Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors
    • Lee, G. S., and Simons, S. S., Jr. (2011) Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors. Biochemistry 50, 356-366
    • (2011) Biochemistry , vol.50 , pp. 356-366
    • Lee, G.S.1    Simons Jr., S.S.2
  • 38
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • Chen, J. D., and Evans, R. M. (1995) A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377, 454-457
    • (1995) Nature , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 42
    • 0030998327 scopus 로고    scopus 로고
    • Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes
    • DOI 10.1210/me.11.6.682
    • Söderström, M., Vo, A., Heinzel, T., Lavinsky, R. M., Yang, W. M., Seto, E., Peterson, D. A., Rosenfeld, M. G., and Glass, C. K. (1997) Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes. Mol. Endocrinol. 11, 682-692 (Pubitemid 27225296)
    • (1997) Molecular Endocrinology , vol.11 , Issue.6 , pp. 682-692
    • Soderstrom, M.1    Vo, A.2    Heinzel, T.3    Lavinsky, R.M.4    Yang, W.-M.5    Seto, E.6    Peterson, D.A.7    Rosenfeld, M.G.8    Glass, C.K.9
  • 43
    • 0025336236 scopus 로고
    • Progesterone as a bone-trophic hormone
    • Prior, J. C. (1990) Progesterone as a bone-trophic hormone. Endocr. Rev. 11, 386-398
    • (1990) Endocr. Rev. , vol.11 , pp. 386-398
    • Prior, J.C.1
  • 44
    • 0032076866 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis. Prevention and treatment
    • Ziegler, R., and Kasperk, C. (1998) Glucocorticoid-induced osteoporosis. Prevention and treatment. Steroids 63, 344-348
    • (1998) Steroids , vol.63 , pp. 344-348
    • Ziegler, R.1    Kasperk, C.2
  • 45
    • 85047682043 scopus 로고    scopus 로고
    • Overlapping but distinct gene regulation profiles by glucocorticoids and progestins in human breast cancer cells
    • DOI 10.1210/me.16.6.1204
    • Wan, Y., and Nordeen, S. K. (2002) Overlapping but distinct gene regulation profiles by glucocorticoids and progestins in human breast cancer cells. Mol. Endocrinol. 16, 1204-1214 (Pubitemid 34621070)
    • (2002) Molecular Endocrinology , vol.16 , Issue.6 , pp. 1204-1214
    • Wan, Y.1    Nordeen, S.K.2
  • 46
    • 39149118308 scopus 로고    scopus 로고
    • Differential modulation of glucocorticoid and progesterone receptor transactivation
    • Szapary, D., Song, L. N., He, Y., and Simons, S. S., Jr. (2008) Differential modulation of glucocorticoid and progesterone receptor transactivation. Mol. Cell. Endocrinol. 283, 114-126
    • (2008) Mol. Cell. Endocrinol. , vol.283 , pp. 114-126
    • Szapary, D.1    Song, L.N.2    He, Y.3    Simons Jr., S.S.4
  • 47
    • 0035154447 scopus 로고    scopus 로고
    • New antiprogestins with partial agonist activity: Potential selective progesterone receptor modulators (SPRMs) and probes for receptor- and coregulator-induced changes in progesterone receptor induction properties
    • DOI 10.1210/me.15.2.255
    • Giannoukos, G., Szapary, D., Smith, C. L., Meeker, J. E., and Simons, S. S., Jr. (2001) New antiprogestins with partial agonist activity. Potential selective progesterone receptor modulators (SPRMs) and probes for receptorand coregulator-induced changes in progesterone receptor induction properties. Mol. Endocrinol. 15, 255-270 (Pubitemid 32128706)
    • (2001) Molecular Endocrinology , vol.15 , Issue.2 , pp. 255-270
    • Giannoukos, G.1    Szapary, D.2    Smith, C.L.3    Meeker, J.E.W.4    Stoney Jr., S.S.5
  • 50
    • 0026666791 scopus 로고
    • Ordering gene function. The interpretation of epistasis in regulatory hierarchies
    • Avery, L., and Wasserman, S. (1992) Ordering gene function. The interpretation of epistasis in regulatory hierarchies. Trends Genet. 8, 312-316
    • (1992) Trends Genet. , vol.8 , pp. 312-316
    • Avery, L.1    Wasserman, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.