Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length

Developmental Biology

Volumn 385, Issue 1, 2014, Pages 67-82

  Mis, Emily K ^a   Liem, Karel F ^a   Kong, Yong ^a,b   Schwartz, Nancy B ^c   Domowicz, Miriam ^c   Weatherbee, Scott D ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Chondrocytes; CSPGs; Dwarfism; Forward genetics; Glycosaminoglycans; HSPGs; Proteoglycans; Skeletal development; Xylt1

Indexed keywords

ETHYLNITROSOUREA; GLYCOSAMINOGLYCAN; PROTEOGLYCAN; TRANSFERASE; UNCLASSIFIED DRUG; XYLOSE; XYLOSYLTRANSFERASE; XYLOSYLTRANSFERASE 1;

ACHONDROPLASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; BONE DYSPLASIA; BONE LENGTH; CARTILAGE CELL; CATALYSIS; CELL MATURATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DWARFISM; ELLIS VAN CREVELD SYNDROME; EMBRYO; ENZYME ACTIVITY; FEMALE; GENE ACTIVITY; GENE MAPPING; GENE SEQUENCE; LEG LENGTH; MALE; MISSENSE MUTATION; MOUSE; MUTAGENESIS; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; THANATOPHORIC DWARFISM; XYLT1 GENE; ADULT; ANIMAL CELL; ANIMAL TISSUE; BONE MINERALIZATION; CHONDROGENESIS; EXTRACELLULAR MATRIX; GENETIC CONSERVATION; GENETIC VARIABILITY; HIGH THROUGHPUT SEQUENCING; HOMOZYGOSITY; IMMUNOFLUORESCENCE TEST; MICRO-COMPUTED TOMOGRAPHY; MORPHOLOGY; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION;

MAMMALIA; VERTEBRATA;

EID: 84888291367     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2013.10.014     Document Type: Article

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