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Volumn 36, Issue 3, 2005, Pages 379-386

EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development

Author keywords

Chondrocyte; Endochondral bone; Multiple Hereditary Exostoses

Indexed keywords

HEPARAN SULFATE; SONIC HEDGEHOG PROTEIN;

EID: 15544381797     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.09.025     Document Type: Article
Times cited : (65)

References (32)
  • 3
    • 0029090221 scopus 로고
    • Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)
    • J. Ahn, H.J. Ludecke, S. Lindow, W.A. Horton, B. Lee, and M.J. Wagner Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1) Nat. Genet. 11 1995 137 143
    • (1995) Nat. Genet. , vol.11 , pp. 137-143
    • Ahn, J.1    Ludecke, H.J.2    Lindow, S.3    Horton, W.A.4    Lee, B.5    Wagner, M.J.6
  • 4
    • 0029764629 scopus 로고    scopus 로고
    • The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes
    • D. Stickens, G. Clines, D. Burbee, P. Ramos, S. Thomas, and D. Hogue The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes Nat. Genet. 14 1996 25 32
    • (1996) Nat. Genet. , vol.14 , pp. 25-32
    • Stickens, D.1    Clines, G.2    Burbee, D.3    Ramos, P.4    Thomas, S.5    Hogue, D.6
  • 5
    • 0031051305 scopus 로고    scopus 로고
    • Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family
    • C.A. Wise, G.A. Clines, H. Massa, B.J. Trask, and M. Lovett Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family Genome Res. 7 1997 10 16
    • (1997) Genome Res. , vol.7 , pp. 10-16
    • Wise, C.A.1    Clines, G.A.2    Massa, H.3    Trask, B.J.4    Lovett, M.5
  • 7
    • 0032481245 scopus 로고    scopus 로고
    • Structure, chromosomal location, and expression profile of EXTR1 and EXTR2, new members of the multiple exostoses gene family
    • T. Saito, N. Seki, M. Yamauchi, S. Tsuji, A. Hayashi, and S. Kozuma Structure, chromosomal location, and expression profile of EXTR1 and EXTR2, new members of the multiple exostoses gene family Biochem. Biophys. Res. Commun. 243 1998 61 66
    • (1998) Biochem. Biophys. Res. Commun. , vol.243 , pp. 61-66
    • Saito, T.1    Seki, N.2    Yamauchi, M.3    Tsuji, S.4    Hayashi, A.5    Kozuma, S.6
  • 8
    • 0032518417 scopus 로고    scopus 로고
    • Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family
    • W. Van Hul, W. Wuyts, J. Hendrickx, F. Speleman, J. Wauters, and K. De Boulle Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family Genomics 47 1998 230 237
    • (1998) Genomics , vol.47 , pp. 230-237
    • Van Hul, W.1    Wuyts, W.2    Hendrickx, J.3    Speleman, F.4    Wauters, J.5    De Boulle, K.6
  • 9
    • 0031837107 scopus 로고    scopus 로고
    • The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate
    • C. McCormick, Y. Leduc, D. Martindale, K. Mattison, L.E. Esford, and A.P. Dyer The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate Nat. Genet. 19 1998 158 161
    • (1998) Nat. Genet. , vol.19 , pp. 158-161
    • McCormick, C.1    Leduc, Y.2    Martindale, D.3    Mattison, K.4    Esford, L.E.5    Dyer, A.P.6
  • 10
    • 0034681139 scopus 로고    scopus 로고
    • The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate
    • C. McCormick, G. Duncan, K.T. Goutsos, and F. Tufaro The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate Proc. Natl. Acad. Sci. U. S. A. 97 2000 668 673
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 668-673
    • McCormick, C.1    Duncan, G.2    Goutsos, K.T.3    Tufaro, F.4
  • 12
    • 0025976838 scopus 로고
    • Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
    • A. Yayon, M. Klagsbrun, J.D. Esko, P. Leder, and D.M. Ornitz Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor Cell 64 1991 841 848
    • (1991) Cell , vol.64 , pp. 841-848
    • Yayon, A.1    Klagsbrun, M.2    Esko, J.D.3    Leder, P.4    Ornitz, D.M.5
  • 13
    • 0033951768 scopus 로고    scopus 로고
    • FGFs, heparan sulfate and FGFRs: Complex interactions essential for development
    • D.M. Ornitz FGFs, heparan sulfate and FGFRs: complex interactions essential for development Bioessays 22 2000 108 112
    • (2000) Bioessays , vol.22 , pp. 108-112
    • Ornitz, D.M.1
  • 14
    • 0035152025 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
    • G.H. Baeg, X. Lin, N. Khare, S. Baumgartner, and N. Perrimon Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless Development 128 2001 87 94
    • (2001) Development , vol.128 , pp. 87-94
    • Baeg, G.H.1    Lin, X.2    Khare, N.3    Baumgartner, S.4    Perrimon, N.5
  • 15
    • 0242384900 scopus 로고    scopus 로고
    • Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins
    • T. Takada, T. Katagiri, M. Ifuku, N. Morimura, M. Kobayashi, and K. Hasegawa Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins J. Biol. Chem. 278 2003 43229 43235
    • (2003) J. Biol. Chem. , vol.278 , pp. 43229-43235
    • Takada, T.1    Katagiri, T.2    Ifuku, M.3    Morimura, N.4    Kobayashi, M.5    Hasegawa, K.6
  • 16
    • 0042661060 scopus 로고    scopus 로고
    • Heparan sulfate is required for bone morphogenetic protein-7 signaling
    • A. Irie, H. Habuchi, K. Kimata, and Y. Sanai Heparan sulfate is required for bone morphogenetic protein-7 signaling Biochem. Biophys. Res. Commun. 308 2003 858 865
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 858-865
    • Irie, A.1    Habuchi, H.2    Kimata, K.3    Sanai, Y.4
  • 17
    • 0037127221 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans retain Noggin at the cell surface: A potential mechanism for shaping bone morphogenetic protein gradients
    • S. Paine-Saunders, B.L. Viviano, A.N. Economides, and S. Saunders Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients J. Biol. Chem. 277 2002 2089 2096
    • (2002) J. Biol. Chem. , vol.277 , pp. 2089-2096
    • Paine-Saunders, S.1    Viviano, B.L.2    Economides, A.N.3    Saunders, S.4
  • 18
    • 0032474837 scopus 로고    scopus 로고
    • Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion
    • Y. Bellaiche, I. The, and N. Perrimon Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion Nature 394 1998 85 88
    • (1998) Nature , vol.394 , pp. 85-88
    • Bellaiche, Y.1    The, I.2    Perrimon, N.3
  • 19
    • 0028837742 scopus 로고
    • Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
    • M.J. Bitgood, and A.P. McMahon Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo Dev. Biol. 172 1995 126 138
    • (1995) Dev. Biol. , vol.172 , pp. 126-138
    • Bitgood, M.J.1    McMahon, A.P.2
  • 20
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • A. Vortkamp, K. Lee, B. Lanske, G.V. Segre, H.M. Kronenberg, and C.J. Tabin Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein Science 273 1996 613 622
    • (1996) Science , vol.273 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 21
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    • B. St-Jacques, M. Hammerschmidt, and A.P. McMahon Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation Genes Dev. 13 1999 2072 2086
    • (1999) Genes Dev. , vol.13 , pp. 2072-2086
    • St-Jacques, B.1    Hammerschmidt, M.2    McMahon, A.P.3
  • 22
    • 0035691559 scopus 로고    scopus 로고
    • Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
    • F. Long, X.M. Zhang, S. Karp, Y. Yang, and A.P. McMahon Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation Development 128 2001 5099 5108
    • (2001) Development , vol.128 , pp. 5099-5108
    • Long, F.1    Zhang, X.M.2    Karp, S.3    Yang, Y.4    McMahon, A.P.5
  • 23
    • 0034663225 scopus 로고    scopus 로고
    • Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice
    • X. Lin, G. Wei, Z. Shi, L. Dryer, J.D. Esko, and D.E. Wells Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice Dev. Biol. 224 2000 299 311
    • (2000) Dev. Biol. , vol.224 , pp. 299-311
    • Lin, X.1    Wei, G.2    Shi, Z.3    Dryer, L.4    Esko, J.D.5    Wells, D.E.6
  • 24
    • 0019126423 scopus 로고
    • Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S
    • M.J. McLeod Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S Teratology 22 1980 299 301
    • (1980) Teratology , vol.22 , pp. 299-301
    • McLeod, M.J.1
  • 25
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • P. Ducy, R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 1997 747 754
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 26
    • 0027488970 scopus 로고
    • Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition
    • O. Jacenko, P.A. LuValle, and B.R. Olsen Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition Nature 365 1993 56 61
    • (1993) Nature , vol.365 , pp. 56-61
    • Jacenko, O.1    Luvalle, P.A.2    Olsen, B.R.3
  • 27
    • 0030027059 scopus 로고    scopus 로고
    • Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
    • L.V. Goodrich, R.L. Johnson, L. Milenkovic, J.A. McMahon, and M.P. Scott Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog Genes Dev. 10 1996 301 312
    • (1996) Genes Dev. , vol.10 , pp. 301-312
    • Goodrich, L.V.1    Johnson, R.L.2    Milenkovic, L.3    McMahon, J.A.4    Scott, M.P.5
  • 28
    • 0033924650 scopus 로고    scopus 로고
    • EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis
    • D. Stickens, D. Brown, and G.A. Evans EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis Dev. Dyn. 218 2000 452 464
    • (2000) Dev. Dyn. , vol.218 , pp. 452-464
    • Stickens, D.1    Brown, D.2    Evans, G.A.3
  • 29
    • 9344241375 scopus 로고    scopus 로고
    • PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth
    • B. Lanske, A.C. Karaplis, K. Lee, A. Luz, A. Vortkamp, and A. Pirro PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth Science 273 1996 663 666
    • (1996) Science , vol.273 , pp. 663-666
    • Lanske, B.1    Karaplis, A.C.2    Lee, K.3    Luz, A.4    Vortkamp, A.5    Pirro, A.6
  • 30
    • 0034747252 scopus 로고    scopus 로고
    • BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation
    • E. Minina, H.M. Wenzel, C. Kreschel, S. Karp, W. Gaffield, and A.P. McMahon BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation Development 128 2001 4523 4534
    • (2001) Development , vol.128 , pp. 4523-4534
    • Minina, E.1    Wenzel, H.M.2    Kreschel, C.3    Karp, S.4    Gaffield, W.5    McMahon, A.P.6
  • 31
    • 0033212987 scopus 로고    scopus 로고
    • Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan
    • I. The, Y. Bellaiche, and N. Perrimon Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan Mol. Cell 4 1999 633 639
    • (1999) Mol. Cell , vol.4 , pp. 633-639
    • The, I.1    Bellaiche, Y.2    Perrimon, N.3
  • 32
    • 2942538442 scopus 로고    scopus 로고
    • Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification
    • L. Koziel, M. Kunath, O.G. Kelly, and A. Vortakmp Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification Dev. Cell 6 6 2004 801 813
    • (2004) Dev. Cell , vol.6 , Issue.6 , pp. 801-813
    • Koziel, L.1    Kunath, M.2    Kelly, O.G.3    Vortakmp, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.