Mutations in fam20b and xylt1 reveal that cartilage matrix controls timing of endochondral ossification by inhibiting chondrocyte maturation

PLoS Genetics

Volumn 7, Issue 8, 2011, Pages

  Eames, B Frank ^a   Yan, Yi Lin ^a   Swartz, Mary E ^a,c   Levic, Daniel S ^b   Knapik, Ela W ^b   Postlethwait, John H ^a   Kimmel, Charles B ^a  

^a UNIVERSITY OF OREGON   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; COLLAGEN TYPE 10; COLLAGEN TYPE 10A1; PROTEOGLYCAN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR RUNX2B; UNCLASSIFIED DRUG; COLLAGEN; FAM20B PROTEIN, ZEBRAFISH; GLYCOSYLTRANSFERASE; PHOSPHOTRANSFERASE; PROTEOCHONDROITIN SULFATE; UDP XYLOSE PROTEIN XYLOSYLTRANSFERASE; UDP XYLOSE-PROTEIN XYLOSYLTRANSFERASE; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CARTILAGE CELL; CARTILAGE MATRIX; CELL MATURATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DEVELOPMENTAL GENE; EMBRYO; ENCHONDRAL OSSIFICATION; FAM20B GENE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GROWTH INHIBITION; NONHUMAN; PROTEIN EXPRESSION; PROTEOGLYCAN SYNTHESIS; XYLOSYLTRANSFERASE 1 GENE; ZEBRA FISH; ANIMAL; BIOSYNTHESIS; CARTILAGE; CELL CULTURE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; ULTRASTRUCTURE;

DANIO RERIO;

ANIMALS; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; CHONDROITIN SULFATE PROTEOGLYCANS; COLLAGEN; HEDGEHOG PROTEINS; MUTATION; OSTEOGENESIS; PENTOSYLTRANSFERASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 80052327147     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002246     Document Type: Article

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