The acid-secreting parietal cell as an endocrine source of sonic hedgehog during gastric repair

Endocrinology

Volumn 154, Issue 12, 2013, Pages 4627-4639

  Engevik, Amy C ^a   Feng, Rui ^a   Yang, Li ^a   Zavros, Yana ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; CXCL3 CHEMOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; SONIC HEDGEHOG PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; SHH PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DNA FLANKING REGION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIZATION; EXON; FEMALE; GENE EXPRESSION; GRANULATION TISSUE; IMMUNOHISTOCHEMISTRY; LOXP SITE; MALE; MOUSE; NONHUMAN; PARABIOSIS; PRIORITY JOURNAL; PROMOTER REGION; STOMACH; STOMACH ACID SECRETION; STOMACH EPITHELIUM; STOMACH PARIETAL CELL; STOMACH ULCER; TISSUE REPAIR; ULCER HEALING; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; TOXICITY; TRANSGENIC MOUSE; WOUND HEALING;

ACETIC ACID; ANIMALS; CELL LINE; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PARABIOSIS; PARIETAL CELLS, GASTRIC; STOMACH; STOMACH ULCER; WOUND HEALING;

EID: 84888272896     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1483     Document Type: Article

References (46)

1. Grassi M, Petraccia L, Mennuni G, et al. Changes, functional disorders, and diseases in the gastrointestinal tract of elderly. Nutr Hosp. 2011;26:659-668.
2. Feldman M, Cryer B, McArthur KE, Huet BA, Lee E. Effects of aging and gastritis on gastric acid and pepsin secretion in humans: a prospective study. Gastroenterology. 1996;110:1043-1052.
3. Pilotto A, Franceschi M, Leandro G, Di Mario F, Valerio G. The effect of Helicobacter pylori infection on NSAID-related gastroduodenal damage in the elderly. Eur J Gastroenterol Hepatol. 1997;9:951-956.
4. Somerville K, Faulkner G, Langman M. Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer. Lancet. 1986;1:462-464.
5. Everhart JE. Recent developments in the epidemiology of Helicobacter pylori. Gastroenterol Clin North Am. 2000;29:559-578.
6. Pleis JR, Lucas JW. Summary health statistics for US adults: National Health Interview Survey, 2007. Vital Health Stat. 2009;10:240.
7. Tarnawski AS. Cellular and molecular mechanisms of gastrointestinal ulcer healing. Dig Dis Sci. 2005;50:S24-S33.
8. Chiang C, Litingtung Y, Lee E, et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature. 1996;383:407-413.
9. Palladino M, Gatto I, Neri V, et al. Pleiotropic beneficial effects of sonic hedgehog gene therapy in an experimental model of peripheral limb ischemia. Mol Ther. 2011;19:658-666.
10. Fitch PM, Howie SE, Wallace WA. Oxidative damage and TGF-β differentially induce lung epithelial cell sonic hedgehog and tenascin-C expression: implications for the regulation of lung remodelling in idiopathic interstitial lung disease. Int J Exp Pathol. 2011;92:8-17.
11. Levi B, James AW, Nelson ER, et al. Human adipose-derived stromal cells stimulate autogenous skeletal repair via paracrine Hedgehog signaling with calvarial osteoblasts. Stem Cells. 2011;20:243-257.
12. Fujita K, Miyamoto T, Saika S. Sonic hedgehog: its expression in a healing cornea and its role in neovascularization. Mol Vis. 2009;15:1036-1044.
13. Kang DH, Han ME, Song MH, et al. The role of hedgehog signaling during gastric regeneration. J Gastroenterol. 2009;44:372-379.
14. Xiao C, Feng R, Engevik A, et al. Sonic Hedgehog contributes to gastric mucosal restitution after injury. Lab Invest. 2013;93:96-111.
15. Zavros Y, Waghray M, Tessier A, et al. Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation. J Biol Chem. 2007;282:33265-33274.
16. Zavros Y, Orr MA, Xiao C, Malinowska DH. Sonic hedgehog is associated with H+,K+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation. Am J Physiol. 2008;295:G99-G111.
17. Xiao C, Ogle SA, Schumacher MA, et al. Loss of parietal cell expression of sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells. Gastroenterology. 2010;138:550-561.
18. Beales IL. Gastrin and interleukin-1β stimulate growth factor secretion from cultured rabbit gastric parietal cells. Life Sci. 2004;75:2983-2995.
19. Miyaoka Y, Kadowaki Y, Ishihara S, et al. Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages. Oncogene. 2004;23:3572-3579.
20. Ueyama T, Shirasawa N, Numazawa M, et al. Gastric parietal cells: potent endocrine role in secreting estrogen as a possible regulator of gastro-hepatic axis. Endocrinology. 2002;143:3162-3170.
21. Le Goascogne C, Sananès N, Eychenne B, Gouézou M, Baulieu EE, Robel P. Androgen biosynthesis in the stomach: expression of cytochrome P450 17 α-hydroxylase/17,20-lyase messenger ribonucleic acid and protein, and metabolism of pregnenolone and progesterone by parietal cells of the rat gastric mucosa. Endocrinology. 1995;136:1744-1752.
22. Okabe S, Amagase K. An overview of acetic acid ulcer models-the history and state of the art of peptic ulcer research. Biol Pharm Bull. 2005;28:1321-1341.
23. Duyverman AM, Kohno M, Duda DG, Jain RK, Fukumura D. A transient parabiosis skin transplantation model in mice. Nature Protoc. 2012;7:763-770.
24. Jiang Q, Oldenburg R, Otsuru S, Grand-Pierre AE, Horwitz EM, Uitto J. Parabiotic heterogenetic pairing of Abcc6-/-/Rag1-/- mice and their wild-type counterparts halts ectopic mineralization in a murine model of pseudoxanthoma elasticum. Am J Pathol. 2010;176:1855-1862.
25. Williams KP, Rayhorn P, Chi-Rosso G, et al. Functional antagonists of sonic hedgehog reveal the importance of the N terminus for activity. J Cell Sci. 1999;112:4405-4414.
26. Wright NA, Pike CM, Elia G. Ulceration induces a novel epidermal growth factor-secreting cell lineage in human gastrointestinal mucosa. Digestion. 1990;46:125-133.
27. Longman RJ, Douthwaite J, Sylvester PA, et al. Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. Gut. 2000;47:792-800.
28. Patel K, Hanby AM, Ahnen DJ, Playford RJ, Wright NA. The kinetic organization of the ulcer-associated cell lineage (UACL): delineation of a novel putative stem-cell region. Epithelial Cell Biol. 1994;3:156-160.
29. Stone DM, Hynes M, Armanini M, et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nautre. 1996;384:129-134.
30. Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 1996;10:301-312.
31. Etheridge LA, Crawford TQ, Zhang S, Roelink H. Evidence for a role of vertebrate Disp1 in long-range Shh signaling. Development. 2010;137:133-140.
32. Ma Y, Erkner A, Gong R, et al. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell. 2002;111:63.
33. Stepan V, Ramamoorthy S, Nitsche H, Zavros Y, Merchant JL, Todisco A. Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells. J Biol Chem. 2005;280:15700-15708.
34. Van Den Brink GR, Hardwick JC, Tytgat GN, et al. Sonic hedgehog regulates gastric gland morphogenesis in man and mouse. Gastroenterology. 2001;121:317-328.
35. Nam KT, Varro A, Coffey RJ, Goldenring JR. Potentiation of oxyntic atrophy-induced gastric metaplasia in amphiregulin-deficient mice. Gastroenterology. 2007;132:1804-1819.
36. Chen MC, Lee AT, Karnes WE, et al. Paracrine control of gastric epithelial cell growth in culture by transforming growth factor-α. Am J Physiol. 1993;264:G390-G396.
37. Beauchamp RD, Barnard JA, McCutchen CM, Cherner JA, Coffey RJ Jr. Localization of transforming growth factor a and its receptor in gastric mucosal cells. J Clin Invest. 1989;84:1017-1023.
38. Stepan V, Pausawasdi N, Ramamoorthy S, Todisco A. The Akt and MAPKsignal-transduction pathways regulate growth factor actions in isolated gastric parietal cells. Gastroenterology. 2004;127:1150-1161.
39. Pietramaggiori G, Scherer SS, Alperovich M, Chen B, Orgill DP, Wagers AJ. Improved cutaneous healing in diabetic mice exposed to healthy peripheral circulation. J Invest Dermatol. 2009;129:2265-2274.
40. Schumacher MA, Donnelly JM, Engevik AC, et al. Gastric sonic hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori. Gastroenterology. 2012;142:1150-1159.
41. Wright NA, Pike C, Elia G. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells. Nature. 1990;343:82-85.
42. Pereira TA, Xie G, Choi SS, et al. Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni. Liver Int. 2013;33:149-161.
43. Stewart GA, Hoyne G, Ahmad SA, et al. Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes. J Pathol. 2003;199:488-495.
44. Stewart GA, Lowrey J, Wakelin SJ, et al. Sonic hedgehog signaling modulates activation of and cytokine production by human peripheral CD4+ T cells. J Immunol. 2002;169:5451-5457.
45. Dunaeva M, Voo S, van Oosterhoud C, Waltenberger J. Sonic hedgehog is a potent chemoattractant for human monocytes: diabetes mellitus inhibits Sonic hedgehog-induced monocyte chemotaxis. Basic Res Cardiol. 2010;105:61-71.
46. El-Zaatari M, Daignault S, Tessier A, et al. Plasma Shh levels reduced in pancreatic cancer patients. Pancreas. 2012;41:1019-1028.