Potentiation of Oxyntic Atrophy-Induced Gastric Metaplasia in Amphiregulin-Deficient Mice

Gastroenterology

Volumn 132, Issue 5, 2007, Pages 1804-1819

  Nam, Ki Taek ^a   Varro, Andrea ^b   Coffey, Robert J ^a   Goldenring, James R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; BROXURIDINE; CELL MARKER; INTRINSIC FACTOR; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE; TRANSFORMING GROWTH FACTOR ALPHA; TREFOIL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATROPHY; CELL CYCLE; CELL LINEAGE; CELL LOSS; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MOUSE; NONHUMAN; OXYNTIC ATROPHY; PRIORITY JOURNAL; SPASMOLYTIC POLYPEPTIDE EXPRESSING METAPLASIA; STOMACH MUCOSA; STOMACH PARIETAL CELL; WILD TYPE;

EID: 34247577577     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2007.03.040     Document Type: Article

References (49)

1. El-Zimaity H.M., Ota H., Graham D.Y., Akamatsu T., and Katsuyama T. Patterns of gastric atrophy in intestinal type gastric carcinoma. Cancer 94 (2002) 1428-1436
2. Parsonnet J., Friedman G.D., Vandersteen D.P., Chang Y., Vogelman J.H., Orentreich N., and Sibley R.K. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 325 (1991) 1127-1131
3. Blaser M.J., and Parsonnet J. Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J Clin Invest 94 (1994) 4-8
4. Correa P. A human model of gastric carcinogenesis. Cancer Res 48 (1988) 3554-3560
5. Smith V.C., and Genta R.M. Role of Helicobacter pylori gastritis in gastric atrophy, intestinal metaplasia, and gastric neoplasia. Microsc Res Tech 48 (2000) 313-320
6. Filipe M.I., Munoz N., Matko I., Kato I., Pompe-Kirn V., Jutersek A., Teuchmann S., Benz M., and Prijon T. Intestinal metaplasia types and the risk of gastric cancer: a cohort study in Slovenia. Int J Cancer 57 (1994) 324-329
7. Goldenring J.R., and Nomura S. Differentiation of the gastric mucosa III. Animal models of oxyntic atrophy and metaplasia. Am J Physiol 291 (2006) G999-G1004
8. Goldenring J.R., Ray G.S., Coffey R.J., Meunier P.C., Haley P.J., Barnes T.B., and Car B.D. Reversible drug-induced oxyntic atrophy in rats. Gastroenterology 118 (2000) 1080-1093
9. Schmidt P.H., Lee J.R., Joshi V., Playford R.J., Poulsom R., Wright N.A., and Goldenring J.R. Identification of a metaplastic cell lineage associated with human gastric adenocarcinoma. Lab Invest 79 (1999) 639-646
10. Wang T.C., Goldenring J.R., Dangler C., Ito S., Mueller A., Jeon W.K., Koh T.J., and Fox J.G. Mice lacking secretory phospholipase A2 show altered apoptosis and differentiation with Helicobacter felis infection. Gastroenterology 114 (1998) 675-689
11. Dhar D.K., Wang T.C., Maruyama R., Udagawa J., Kubota H., Fuji T., Tachibana M., Ono T., Otani H., and Nagasue N. Expression of cytoplasmic TFF2 is a marker of tumor metastasis and negative prognostic factor in gastric cancer. Lab Invest 83 (2003) 1343-1352
12. Halldorsdottir A.M., Sigurdardottrir M., Jonasson J.G., Oddsdottir M., Magnusson J., Lee J.R., and Goldenring J.R. Spasmolytic polypeptide-expressing metaplasia (SPEM) associated with gastric cancer in Iceland. Dig Dis Sci 48 (2003) 431-441
13. Fox J.G., Li X., Cahill R.J., Andrutis K., Rustgi A.K., Odze R., and Wang T.C. Hypertrophic gastropathy in Helicobacter felis-infected wild-type C57BL/6 mice and p53 hemizygous transgenic mice. Gastroenterology 110 (1996) 155-166
14. Wang T.C., Dangler C.A., Chen D., Goldenring J.R., Koh T., Raychowdhury R., Coffey R.J., Ito S., Varro A., Dockray G.J., and Fox J.G. Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer. Gastroenterology 118 (2000) 36-47
15. Akagi M., Yokozaki H., Kitadai Y., Ito R., Yasui W., Haruma K., Kajiyama G., and Tahara E. Expression of amphiregulin in human gastric cancer cell lines. Cancer 75 (1995) 1460-1466
16. Beauchamp R.D., Barnard J.A., McCutchen C.M., Cherner J.A., and Coffey Jr. R.J. Localization of transforming growth factor alpha and its receptor in gastric mucosal cells. Implications for a regulatory role in acid secretion and mucosal renewal. J Clin Invest 84 (1989) 1017-1023
17. Cook P.W., Pittelkow M.R., Keeble W.W., Graves-Deal R., Coffey Jr. R.J., and Shipley G.D. Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas. Cancer Res 52 (1992) 3224-3227
18. Dempsey P.J., Goldenring J.R., Soroka C.J., Modlin I.M., McClure R.W., Lind C.D., Ahlquist D.A., Pittelkow M.R., Lee D.C., Sandgren E.P., et al. Possible role of transforming growth factor alpha in the pathogenesis of Menetrier's disease: supportive evidence form humans and transgenic mice. Gastroenterology 103 (1992) 1950-1963
19. Kitadai Y., Yasui W., Yokozaki H., Kuniyasu H., Ayhan A., Haruma K., Kajiyama G., Johnson G.R., and Tahara E. Expression of amphiregulin, a novel gene of the epidermal growth factor family, in human gastric carcinomas. Jpn J Cancer Res 84 (1993) 879-884
20. Murayama Y., Miyagawa J., Higashiyama S., Kondo S., Yabu M., Isozaki K., Kayanoki Y., Kanayama S., Shinomura Y., Taniguchi N., et al. Localization of heparin-binding epidermal growth factor-like growth factor in human gastric mucosa. Gastroenterology 109 (1995) 1051-1059
21. Nomura S., Yamaguchi H., Ogawa M., Wang T.C., Lee J.R., and Goldenring J.R. Alterations in gastric mucosal lineages induced by acute oxyntic atrophy in wild-type and gastrin-deficient mice. Am J Physiol 288 (2005) G362-G375
22. Ogawa M., Nomura S., Varro A., Wang T.C., and Goldenring J.R. Altered metaplastic response of waved-2 EGF receptor mutant mice to acute oxyntic atrophy. Am J Physiol 290 (2006) G793-G804
23. Goldenring J.R., Poulsom R., Ray G.S., Wright N., Meise K.S., and Coffey Jr. R.J. Expression of trefoil peptides in the gastric mucosa of transgenic mice overexpressing transforming growth factor-alpha. Growth Factors 13 (1996) 111-119
24. Takaishi S., Cui G., Frederick D.M., Carlson J.E., Houghton J., Varro A., Dockray G.J., Ge Z., Whary M.T., Rogers A.B., Fox J.G., and Wang T.C. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer. Gastroenterology 128 (2005) 1965-1983
25. Kinoshita Y., Nakata H., Hassan S., Asahara M., Kawanami C., Matsushima Y., Naribayashi-Inomoto Y., Ping C.Y., Min D., Nakamura A., et al. Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions. Gastroenterology 109 (1995) 1068-1077
26. Miyazaki Y., Shinomura Y., Tsutsui S., Zushi S., Higashimoto Y., Kanayama S., Higashiyama S., Taniguchi N., and Matsuzawa Y. Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor. Gastroenterology 116 (1999) 78-89
27. Rutten M.J., Dempsey P.J., Solomon T.E., and Coffey Jr. R.J. TGF-alpha is a potent mitogen for primary cultures of guinea pig gastric mucous epithelial cells. Am J Physiol 265 (1993) G361-G369
28. Chung E., Graves-Deal R., Franklin J.L., and Coffey R.J. Differential effects of amphiregulin and TGF-alpha on the morphology of MDCK cells. Exp Cell Res 309 (2005) 149-160
29. Franic T.V., Judd L.M., Nguyen N.V., Samuelson L.C., Loveland K.L., Giraud A.S., Gleeson P.A., and van Driel I.R. Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis. Am J Physiol 287 (2004) G910-G918
30. Romano M., Ricci V., Di Popolo A., Sommi P., Del Vecchio Blanco C., Bruni C.B., Ventura U., Cover T.L., Blaser M.J., Coffey R.J., and Zarrilli R. Helicobacter pylori upregulates expression of epidermal growth factor-related peptides, but inhibits their proliferative effect in MKN 28 gastric mucosal cells. J Clin Invest 101 (1998) 1604-1613
31. Luetteke N.C., Qiu T.H., Fenton S.E., Troyer K.L., Riedel R.F., Chang A., and Lee D.C. Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. Development 126 (1999) 2739-2750
32. Luetteke N.C., Qiu T.H., Peiffer R.L., Oliver P., Smithies O., and Lee D.C. TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell 73 (1993) 263-278
33. Colin-Jones D.G. The role and limitations of H2-receptor antagonists in the treatment of gastro-oesophageal reflux disease. Aliment Pharmacol Ther 9 Suppl 1 (1995) 9-14
34. Dieckgraefe B.K., Seetharam B., and Alpers D.H. Developmental regulation of rat intrinsic factor mRNA. Am J Physiol 254 (1988) G913-G919
35. Maton P.N., Lack E.E., Collen M.J., Cornelius M.J., David E., Gardner J.D., and Jensen R.T. The effect of Zollinger-Ellison syndrome and omeprazole therapy on gastric oxyntic endocrine cells. Gastroenterology 99 (1990) 943-950
36. Nagata A., Ito M., Iwata N., Kuno J., Takano H., Minowa O., Chihara K., Matsui T., and Noda T. G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo. Proc Natl Acad Sci U S A 93 (1996) 11825-11830
37. Ryberg B., Axelson J., Hakanson R., Sundler F., and Mattsson H. Trophic effects of continuous infusion of [Leu15]-gastrin-17 in the rat. Gastroenterology 98 (1990) 33-38
38. Koh T.J., Goldenring J.R., Ito S., Mashimo H., Kopin A.S., Varro A., Dockray G.J., and Wang T.C. Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice. Gastroenterology 113 (1997) 1015-1025
39. Chew C.S., Nakamura K., and Petropoulos A.C. Multiple actions of epidermal growth factor and TGF-alpha on rabbit gastric parietal cell function. Am J Physiol 267 (1994) G818-G826
40. Rhodes J.A., Tam J.P., Finke U., Saunders M., Bernanke J., Silen W., and Murphy R.A. Transforming growth factor alpha inhibits secretion of gastric acid. Proc Natl Acad Sci U S A 83 (1986) 3844-3846
41. Tsutsui S., Shinomura Y., Higashiyama S., Higashimoto Y., Miyazaki Y., Kanayama S., Hiraoka S., Minami T., Kitamura S., Murayama Y., Miyagawa J., Taniguchi N., and Matsuzawa Y. Induction of heparin binding epidermal growth factor-like growth factor and amphiregulin mRNAs by gastrin in the rat stomach. Biochem Biophys Res Commun 235 (1997) 520-523
42. Beales I.L. Gastrin and interleukin-1beta stimulate growth factor secretion from cultured rabbit gastric parietal cells. Life Sci 75 (2004) 2983-2995
43. Goldenring J.R., Ray G.S., Soroka C.J., Smith J., Modlin I.M., Meise K.S., and Coffey Jr. R.J. Overexpression of transforming growth factor-alpha alters differentiation of gastric cell lineages. Dig Dis Sci 41 (1996) 773-784
44. Karam S.M., and Leblond C.P. Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell. Anat Rec 236 (1993) 259-279
45. Hanby A.M., Poulsom R., Playford R.J., and Wright N.A. The mucous neck cell in the human gastric corpus: a distinctive, functional cell lineage. J Pathol 187 (1999) 331-337
46. Karam S.M. Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss. Anat Rec 236 (1993) 314-332
47. Karam S.M., and Leblond C.P. Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells. Anat Rec 236 (1993) 297-313
48. Katz J.P., Perreault N., Goldstein B.G., Actman L., McNally S.R., Silberg D.G., Furth E.E., and Kaestner K.H. Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Gastroenterology 128 (2005) 935-945
49. Lopez-Diaz L., Hinkle K.L., Jain R.N., Zavros Y., Brunkan C.S., Keeley T., Eaton K.A., Merchant J.L., Chew C.S., and Samuelson L.C. Parietal cell hyperstimulation and autoimmune gastritis in cholera toxin transgenic mice. Am J Physiol 290 (2006) G970-G979